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1دورية أكاديمية
المؤلفون: Colby S Shemesh, Rosie Z Yu, Hans J Gaus, Sarah Greenlee, Noah Post, Karsten Schmidt, Michael T Migawa, Punit P Seth, Thomas A Zanardi, Thazha P Prakash, Eric E Swayze, Scott P Henry, Yanfeng Wang
المصدر: Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
مصطلحات موضوعية: antisense oligonucleotide, biotransformation, metabolism, N-acetyl galactosamine, targeted drug delivery, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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المؤلفون: Tamilselvan Rajasekaran, Graeme C. Freestone, Rodrigo Galindo-Murillo, Barbara Lugato, Hans Gaus, Michael T. Migawa, Eric. E. Swayze, Thomas E. Cheatham, Punit P. Seth, Stephen Hanessian
المصدر: The Journal of Organic Chemistry. 88:3599-3614
مصطلحات موضوعية: Organic Chemistry
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3
المؤلفون: W. Brad Wan, Audrey Low, Eric E. Swayze, Michael T. Migawa, Guillermo Vasquez, Michael Tanowitz, Punit P. Seth
المصدر: Nucleic Acid Therapeutics. 32:40-50
مصطلحات موضوعية: Stereochemistry, Phosphorothioate Oligonucleotides, Endosomes, Biochemistry, Mice, chemistry.chemical_compound, Therapeutic index, Drug Discovery, Genetics, Animals, Nucleotide, Molecular Biology, chemistry.chemical_classification, Nuclease, biology, Oligonucleotide, Phosphorus, Oligonucleotides, Antisense, Phosphonate, Therapeutic Index, chemistry, biology.protein, Molecular Medicine, Chemical stability, Isopropyl, DNA
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a3100ea938ad4987b8358f461c08ec
https://doi.org/10.1089/nat.2021.0064 -
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المؤلفون: Tamilselvan Rajasekaran, Graeme C. Freestone, Rodrigo Galindo-Murillo, Barbara Lugato, Lorena Rico, Juan C. Salinas, Hans Gaus, Michael T. Migawa, Eric E. Swayze, Thomas E. Cheatham, Stephen Hanessian, Punit P. Seth
المصدر: J Am Chem Soc
Journal of the American Chemical Society, vol 144, iss 4مصطلحات موضوعية: Oligonucleotides, Organophosphonates, Nucleic Acid Hybridization, General Chemistry, Molecular Dynamics Simulation, Biochemistry, Article, Hydrocarbons, Catalysis, Kinetics, Colloid and Surface Chemistry, Chemical Sciences, Nucleic Acid Conformation, RNA
وصف الملف: application/pdf
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5
المؤلفون: Xue-hai Liang, Cheryl L De Hoyos, Punit P. Seth, Stanley T. Crooke, Graeme C Freestone, Michael E Ǿstergaard, Audrey Low, Guillermo Vasquez, Jinghua Yu, Eric E. Swayze, Michael T. Migawa, W. Brad Wan, Thazha P. Prakash
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Male, AcademicSubjects/SCI00010, Ribonuclease H, Biology, 010402 general chemistry, 01 natural sciences, Mice, 03 medical and health sciences, chemistry.chemical_compound, Organophosphorus Compounds, Therapeutic index, Chemical Biology and Nucleic Acid Chemistry, Genetics, Animals, Humans, 030304 developmental biology, Mice, Inbred BALB C, 0303 health sciences, Nuclease, DNA, Oligonucleotides, Antisense, 0104 chemical sciences, Glucose, Liver, chemistry, NIH 3T3 Cells, Biophysics, biology.protein, Nucleic acid, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4975e50676c63a8c248fb49e9635c5
https://doi.org/10.1093/nar/gkab047 -
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المؤلفون: Punit P. Seth, Haibo Jiang, Stephen G. Young, K. Swaminathan Iyer, Paul Guagliardo, Cuiwen He, Kai Chen, Thomas A. Weston, Loren G. Fong, Michael T. Migawa, C. Frank Bennett, Wenxin Song, Michael Tanowitz
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Male, Acetylgalactosamine, Resolution (mass spectrometry), AcademicSubjects/SCI00010, NAR Breakthrough Article, Cesium, Phosphorothioate Oligonucleotides, Spectrometry, Mass, Secondary Ion, Asialoglycoprotein Receptor, Biology, Kidney, Mice, 03 medical and health sciences, Narese/2, 0302 clinical medicine, 3T3-L1 Cells, Sulfur Isotopes, Gene expression, Genetics, Animals, Humans, Inner membrane, Tissue Distribution, Pseudopodia, 030304 developmental biology, 0303 health sciences, Oligonucleotide, Myocardium, HEK 293 cells, RNA, Oligonucleotides, Antisense, Cell biology, Mice, Inbred C57BL, Microscopy, Electron, HEK293 Cells, Liver, Nucleic acid, RNA, Long Noncoding, Nanoscale secondary ion mass spectrometry, Sulfur, 030217 neurology & neurosurgery, HeLa Cells, Subcellular Fractions
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397731af11f124b15e1a8b566724f089
https://doi.org/10.1093/nar/gkaa1112 -
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المؤلفون: Andres Berdeja, Michael T. Migawa, Susan F. Murray, Stanley T. Crooke, W. Brad Wan, Cheryl L De Hoyos, Audrey Low, Xue-hai Liang, Punit P. Seth, Eric E. Swayze, Michael E. Østergaard, Guillermo Vasquez, Wen Shen
المصدر: Nucleic Acids Research
مصطلحات موضوعية: RNase P, Ribonuclease H, Phosphorothioate Oligonucleotides, Cleavage (embryo), Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Chemical Biology and Nucleic Acid Chemistry, Genetics, Animals, 030304 developmental biology, 0303 health sciences, Nuclease, biology, Oligonucleotide, DNA, Oligonucleotides, Antisense, chemistry, 030220 oncology & carcinogenesis, Phosphodiester bond, biology.protein, Biophysics, RNA Cleavage, Chirality (chemistry), Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da31a5f4a9918cb691a94725195e60ae
https://doi.org/10.1093/nar/gkaa031 -
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المصدر: International Journal of Nanomedicine
مصطلحات موضوعية: Programmed cell death, Carcinoma, Hepatocellular, Cell Survival, Biophysics, Pharmaceutical Science, Bioengineering, Context (language use), Apoptosis, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, law.invention, Flow cytometry, Biomaterials, hybrid nanosystems, Confocal microscopy, law, Annexin, International Journal of Nanomedicine, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Viability assay, Molecular Targeted Therapy, Caspase, Original Research, selumetinib, Membrane Potential, Mitochondrial, biology, medicine.diagnostic_test, Chemistry, Organic Chemistry, Liver Neoplasms, General Medicine, hepatocellular carcinoma, Sorafenib, 021001 nanoscience & nanotechnology, 0104 chemical sciences, GalNAc, Nanomedicine, Caspases, Drug delivery, drug delivery, biology.protein, Cancer research, 0210 nano-technology
وصف الملف: text/html
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المصدر: Journal of the American Chemical Society. 142(21)
مصطلحات موضوعية: chemistry.chemical_classification, Mutagenesis (molecular biology technique), Sequence (biology), General Chemistry, Oligonucleotides, Antisense, 010402 general chemistry, Subcellular localization, 01 natural sciences, Biochemistry, Catalysis, In vitro, 0104 chemical sciences, Amino acid, Complementation, DNA-Binding Proteins, Kinetics, Colloid and Surface Chemistry, HEK293 Cells, chemistry, Nucleic acid, Humans, Nucleotide, HeLa Cells, Transcription Factors
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المؤلفون: Sagar S. Damle, Stanley T. Crooke, Rosanne M. Crooke, Wen Shen, Michael T. Migawa, Huynh-Hoa Bui, Xue-hai Liang, Stan Riney, Mark J. Graham, Shiyu Wang, Joyee Yao, Hong Sun
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Male, 0301 basic medicine, Untranslated region, Ribonuclease H, Protein tyrosine phosphatase, Biology, Open Reading Frames, 03 medical and health sciences, Eukaryotic translation, Proto-Oncogene Proteins, Genetics, Protein biosynthesis, Animals, Humans, RNA, Messenger, Molecular Biology, Mice, Inbred BALB C, Messenger RNA, Oligonucleotide, Translation (biology), Oligonucleotides, Antisense, Molecular biology, Cell biology, Lipoproteins, LDL, Open reading frame, 030104 developmental biology, Receptors, LDL, Protein Biosynthesis, Protein Tyrosine Phosphatases, 5' Untranslated Regions
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79dbf01f96e8f0d1acab9a1041c21e3b
https://doi.org/10.1093/nar/gkx632