المؤلفون: Faisal A. Al-Allaf, Zainularifeen Abduljaleel, Mohammad Athar, Mohiuddin M. Taher, Wajahatullah Khan, Huseyin Mehmet, Mukaddes Colakogullari, Sophia Apostolidou, Brian Bigger, Simon Waddington, Charles Coutelle, Michael Themis, Mohammed N. Al-Ahdal, Futwan A. Al-Mohanna, Zuhair N. Al-Hassnan, Abdellatif Bouazzaoui

المصدر: Non-coding RNA Research, Vol 4, Iss 1, Pp 1-14 (2019)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S246805401830088X; https://doaj.org/toc/2468-0540

URL الوصول: https://doaj.org/article/e7460ad473a841058174a80c260fe241

المؤلفون: Maha Tijani, Altar M. Munis, Christopher Perry, Khaled Sanber, Marta Ferraresso, Tarit Mukhopadhyay, Michael Themis, Ilaria Nisoli, Giada Mattiuzzo, Mary K. Collins, Yasuhiro Takeuchi

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 303-312 (2018)

مصطلحات موضوعية: Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050118300779; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/48629033056b46e6a5e465666cc2c703

المؤلفون: Anna L. David, Khalil N. Abi-Nader, Boaz Weisz, S.W. Steven Shaw, Michael Themis, Terence Cook, Charles Coutelle, Charles H. Rodeck, Donald M. Peebles

المصدر: Taiwanese Journal of Obstetrics & Gynecology, Vol 49, Iss 1, Pp 23-29 (2010)

مصطلحات موضوعية: fetus, gene therapy, injection, sheep, stomach, ultrasound, Gynecology and obstetrics, RG1-991

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1028455910600046; https://doaj.org/toc/1028-4559

URL الوصول: https://doaj.org/article/f0c16c092dc049d2a65c6b0d9db9cb04

المؤلفون: Balta Lucendo-Villarin, author¹, Hassan Rashidi, author^{1, 2}, Sharmin Alhaque, author^{1, 3}, Lena Fischer, author^{1, 4}, Jose Meseguer-Ripolles, author¹, Yu Wang, author¹, Cliona O'Farrelly, author⁴, Michael Themis, author³, David C. Hay, author¹

المصدر: Journal of Visualized Experiments. (149)

الإتاحة: http://www.jove.com/video/59965

المؤلفون: Saqlain Suleman, Annette Payne, Johnathan Bowden, Sharmin Al Haque, Marco Zahn, Serena Fawaz, Mohammad S. Khalifa, Susan Jobling, David Hay, Matteo Franco, Raffaele Fronza, Wei Wang, Olga Strobel-Freidekind, Annette Deichmann, Yasuhiro Takeuchi, Simon N. Waddington, Irene Gil-Farina, Manfred Schmidt, Michael Themis

المصدر: Suleman, S, Payne, A, Bowden, J, Al Haque, S, Zahn, M, Fawaz, S, Khalifa, M, Jobling, S, Hay, D C, Franco, M, Fronza, R, Wang, W, Strobel-Freidekind, O, Deichmann, A, Takeuchi, Y, Waddington, S, Gil-Farina, I, Schmidt, M & Themis, M 2022, ' HIV-1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survival. ', Gene Therapy . https://doi.org/10.1038/s41434-022-00335-4

مصطلحات موضوعية: Binding Sites, Virus Integration, Lentivirus, Induced Pluripotent Stem Cells, IS- insertion site, pTFBS- predicted transcription factor binding site, HIV Infections, LV- lentiviral vectors, Mice, stem-cell differentiation, Genetics, HIV-1, Molecular Medicine, Humans, Animals, cancer, genetics, Molecular Biology, Transcription Factors

وصف الملف: Print-Electronic; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9227182434eb9379cb6ad8f4b50bb72a
https://bura.brunel.ac.uk/handle/2438/24506

المؤلفون: Huseyin Mehmet, Wajahatullah Khan, Futwan Al-Mohanna, Zainularifeen Abduljaleel, Simon N. Waddington, Michael Themis, Charles Coutelle, Zuhair N. Al-Hassnan, S Apostolidou, Brian W. Bigger, Mohiuddin M. Taher, Mohammad Athar, Abdellatif Bouazzaoui, Mukaddes Colakogullari, Mohammed N. Al-Ahdal, Faisal A. Al-Allaf

المصدر: Non-coding RNA Research
Non-coding RNA Research, Vol 4, Iss 1, Pp 1-14 (2019)
Al-Allaf, F A, Abduljaleel, Z, Athar, M, Taher, M M, Khan, W, Mehmet, H, Colakogullari, M, Apostolidou, S, Bigger, B, Waddington, S, Coutelle, C, Themis, M, Al-Ahdal, M N, Al-Mohanna, F A, Al-Hassnan, Z N & Bouazzaoui, A 2019, ' Modifying inter-cistronic sequence significantly enhances IRES dependent second gene expression in bicistronic vector : Construction of optimised cassette for gene therapy of familial hypercholesterolemia ', Non-coding RNA research, vol. 4, no. 1, pp. 1-14 . https://doi.org/10.1016/j.ncrna.2018.11.005

مصطلحات موضوعية: 0301 basic medicine, lcsh:QH426-470, Base pair, Internal ribosome entry site, Familial hypercholesterolemia, Biochemistry, Article, 03 medical and health sciences, 0302 clinical medicine, Gene therapy, Cistron, IRES, Gene expression, Genetics, Inter-cistronic sequences, Molecular Biology, Gene, Messenger RNA, Chemistry, Biochemistry (medical), Translation (biology), MD simulation, Transfection, Cell biology, lcsh:Genetics, 030104 developmental biology, 030220 oncology & carcinogenesis, Protein structure modeling

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2100c1b24aef7234acaef960880fc0e2
http://europepmc.org/articles/PMC6404380

المؤلفون: Michael Themis, Rajvinder Karda, Simon N. Waddington, Kuteiba Schrubaji, Saqlain Suleman, Peter Hewitson, Svetlana Ignatova, Chrysovalanto Filippou, Jonathan Huddleston

المصدر: Journal of virological methods. 299

مصطلحات موضوعية: endocrine system, Technology, COVID-19 Vaccines, animal diseases, viruses, Genetic Vectors, Vectors in gene therapy, Biology, Virus, Adenoviridae, adenovirus type 5, chemistry.chemical_compound, viral vector purification, Plasmid, In vivo, vaccine, Virology, PEG ratio, Humans, caesium chloride, Cytotoxicity, Downstream processing, Chromatography, aqueous two-phase partitioning system, SARS-CoV-2, virus diseases, COVID-19, HEK293 Cells, chemistry, Caesium chloride

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a7ca4b1bad208937cd57152f24a440
https://pubmed.ncbi.nlm.nih.gov/34626684

المؤلفون: Michael Themis, David C. Hay, Yu Wang, Hassan Rashidi, Lena Fischer, Balta Lucendo-Villarin, Sharmin Alhaque, Cliona O'Farrelly, Jose Meseguer-Ripolles

المصدر: Lucendo-villarin, B, Rashidi, H, Alhaque, S, Fischer, L, Meseguer-ripolles, J, Wang, Y, O'farrelly, C, Themis, M & Hay, D C 2019, ' Serum Free Production of Three-Dimensional Human Hepatospheres from Pluripotent Stem Cells ', Journal of Visualized Experiments (JoVE), no. 149 . https://doi.org/10.3791/59965

مصطلحات موضوعية: Pluripotent Stem Cells, 0301 basic medicine, defined culture system, Liver cytology, General Chemical Engineering, Cellular differentiation, Induced Pluripotent Stem Cells, Cell, Cell Count, Biology, Culture Media, Serum-Free, General Biochemistry, Genetics and Molecular Biology, stable cell phenotype, 03 medical and health sciences, three-dimensional culture, Spheroids, Cellular, medicine, Humans, Induced pluripotent stem cell, hepatospheres, General Immunology and Microbiology, 030111 toxicology, General Neuroscience, drug metabolism and protein secretion, Cell Differentiation, Embryonic stem cell, Cell biology, Transplantation, 030104 developmental biology, medicine.anatomical_structure, Liver, Liver function, pluripotent stem cells, Developmental biology

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a1ddb083f047be05a00ea6dfadba6e
https://doi.org/10.3791/59965

المؤلفون: Annette M. Payne, Michael Themis, Mohammadmersad Ghorbani

المصدر: Computers in Biology and Medicine. 68:57-66

مصطلحات موضوعية: 0301 basic medicine, DNA sequence, Alu element, Health Informatics, Biology, Bioinformatics, Pattern identification, 03 medical and health sciences, Epigenetics of physical exercise, Methylation in cancer, Alu Elements, CpG, Neoplasms, microRNA, Animals, Humans, RNA, Neoplasm, Computational analysis, Gene, Genetics, Microarray analysis techniques, DNA, Neoplasm, Methylation, DNA Methylation, Neoplasm Proteins, Computer Science Applications, MicroRNAs, 030104 developmental biology, Differentially methylated regions, CpG site, Motif, CpG Islands, Pattern searching algorithm, Genome-Wide Association Study

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e0fe17c2cc1d1eea789f0ee68772d7
https://doi.org/10.1016/j.compbiomed.2015.09.023

المؤلفون: Hassan Rashidi, Michael Themis, Sharmin Alhaque

مصطلحات موضوعية: 0301 basic medicine, 3D culture, Pluripotent Stem Cells, Computer science, Cell Culture Techniques, Cell Differentiation, Computational biology, Articles, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 030104 developmental biology, Pluripotent stem cells, Cell culture, Humans, Identification (biology), Cell Lineage, General Agricultural and Biological Sciences, Induced pluripotent stem cell, Adult stem cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2623e01387079c1d6405231f0c6b60
https://europepmc.org/articles/PMC5974439/