-
1دورية أكاديمية
المؤلفون: Cheryl Tyszkiewicz, Seo-Kyoung Hwang, Balasubramanian Manickam, Ben Jakubczak, Karen M. Walters, Michael W. Bolt, Rosemary Santos, Chang-Ning Liu
المصدر: Frontiers in Toxicology, Vol 5 (2023)
مصطلحات موضوعية: retinal function, toxicity, Wistar Han, sex, electroretinography (ERG), Toxicology. Poisons, RA1190-1270
وصف الملف: electronic resource
-
2دورية أكاديمية
المؤلفون: Michael W. Bolt, Laurence O. Whiteley, Jessica L. Lynch, Brian Lauritzen, Antonio R. Fernández de Henestrosa, Timothy MacLachlan, Peter Ulrich, Binu K. Philip, Prathap Kumar Mahalingaiah, Claudette L. Fuller, David R. Compton
المصدر: Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 89-98 (2020)
وصف الملف: electronic resource
-
3دورية أكاديمية
المؤلفون: Joseph E. McClellan, Hugh D. Conlon, Michael W. Bolt, Vatche Kalfayan, Rameshraja Palaparthy, Muhammad I. Rehman, Carol F. Kirchhoff
المصدر: Therapeutic Advances in Gastroenterology, Vol 12 (2019)
مصطلحات موضوعية: Diseases of the digestive system. Gastroenterology, RC799-869
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1756-2848
-
4
المؤلفون: Peter Ulrich, Michael W. Bolt, Antonio R. Fernández de Henestrosa, Claudette L. Fuller, Prathap Kumar S. Mahalingaiah, David R. Compton, Laurence O. Whiteley, Jessica L. Lynch, Brian Lauritzen, Timothy K. MacLachlan, Binu K. Philip
المصدر: Molecular Therapy: Methods & Clinical Development, Vol 19, Iss, Pp 89-98 (2020)
Molecular Therapy. Methods & Clinical Developmentمصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, lcsh:QH426-470, Genetic enhancement, Harmonization, Viral vector, Toxicology studies, 03 medical and health sciences, 0302 clinical medicine, Genetics, Medicine, lcsh:QH573-671, Intensive care medicine, Molecular Biology, Gene, Modalities, lcsh:Cytology, business.industry, Safety pharmacology, Perspective (graphical), lcsh:Genetics, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine, Original Article, business
-
5
المؤلفون: Lawrence O Whiteley, K Nasir Khan, Michael W. Bolt, Joseph T. Brady
المصدر: The Journal of toxicological sciences. 46(2)
مصطلحات موضوعية: business.industry, Mechanism (biology), Carcinogenesis, Genetic Vectors, Authorization, Neurotoxicity, Gene Transfer Techniques, Genetic Therapy, 010501 environmental sciences, Dependovirus, Toxicology, Bioinformatics, medicine.disease, 030226 pharmacology & pharmacy, 01 natural sciences, Clinical trial, 03 medical and health sciences, 0302 clinical medicine, Mutagenesis, medicine, Humans, Regulatory agency, business, Gene, 0105 earth and related environmental sciences
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c3fde6e6e1aa190476bb02bb20e44a
https://pubmed.ncbi.nlm.nih.gov/33536390 -
6
المؤلفون: Karrie A. Brenneman, Fei Hua, Kay A. Criswell, John E Graves, Michael W. Bolt, Steven Arkin
المصدر: Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 31(1)
مصطلحات موضوعية: 030204 cardiovascular system & hematology, Pharmacology, Fibrinogen, 03 medical and health sciences, Mice, 0302 clinical medicine, Tissue factor pathway inhibitor, Thrombin, medicine, Animals, Humans, Platelet, cardiovascular diseases, Rats, Wistar, Prothrombin time, medicine.diagnostic_test, business.industry, Antithrombin, Anticoagulants, Thrombosis, Hematology, General Medicine, Haplorhini, Rats, Factor Xa, cardiovascular system, Blood Coagulation Tests, business, Protein C, Biomarkers, circulatory and respiratory physiology, 030215 immunology, medicine.drug, Partial thromboplastin time
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f96d32b26f175c9586cf1441929f11b
https://pubmed.ncbi.nlm.nih.gov/31687988 -
7
المؤلفون: Liuqing Wei, Jun Xiao, Joseph S. Warmus, Jeffrey R. Chabot, Robert Dullea, Christopher T. Salatto, David W. Piotrowski, Benjamin A. Thuma, Donna N. Petersen, Chris Limberakis, Julien Genovino, Steven B. Coffey, Michael W. Bolt, Kim F. McClure, Kevin D. Hesp, Spiros Liras, Jamie H. D. Cate, Nathanael G. Lintner, Allyn T. Londregan, Gary Erik Aspnes, Benjamin Reidich
المصدر: Journal of Medicinal Chemistry. 61:5704-5718
مصطلحات موضوعية: Male, 0301 basic medicine, 01 natural sciences, Rats, Sprague-Dawley, Structure-Activity Relationship, 03 medical and health sciences, In vivo, Drug Discovery, Animals, Structure–activity relationship, Protease Inhibitors, 010405 organic chemistry, Chemistry, PCSK9, PCSK9 Inhibitors, Subtilisin, Hit to lead, Proprotein convertase, Small molecule, Rats, 0104 chemical sciences, 030104 developmental biology, Biochemistry, Drug Design, Molecular Medicine, Kexin, Safety
-
8
المؤلفون: Dennis O. Scott, Spiros Liras, Roger B. Ruggeri, Heather Eng, Adam S. Kamlet, Ryosuke Arakawa, David W. Piotrowski, Robert Dullea, Christopher T. Salatto, Karen Atkinson, Michael W. Bolt, Anne-Marie R. Dechert-Schmitt, Paul DaSilva-Jardine, Allyn T. Londregan, Brian Raymer, Kenneth Dahl, Daniel P. Canterbury, Donna N. Petersen, Paula M. Loria, Chris Limberakis, Emi Kimoto, Kim F. McClure, Kevin Beaumont, Liuqing Wei, Akihiro Takano, Kevin P. Maresca, Jun Xiao, Amanda King-Ahmad, Christer Halldin, Benjamin Reidich, Jeffrey R. Chabot
المصدر: Angewandte Chemie International Edition. 56:16218-16222
مصطلحات موضوعية: 0301 basic medicine, Drug, media_common.quotation_subject, Ribosome, Catalysis, Small Molecule Libraries, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Humans, media_common, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, PCSK9, PCSK9 Inhibitors, Subtilisin, General Medicine, General Chemistry, Prodrug, Proprotein convertase, Small molecule, 030104 developmental biology, Liver, Biochemistry, 030220 oncology & carcinogenesis, Hepatocytes, Kexin, Proprotein Convertase 9
-
9
المؤلفون: Chuenlei Parng, Boris Gorovits, Rob Webster, Teresa M Caiazzo, Nicole Duriga, Debra D. Pittman, Michael W. Bolt, Alison Joyce, Beth A. Leary, Victoria Markiewicz, Jianqing Chen, Lisa Dyleski
المصدر: Journal of Pharmaceutical Sciences. 106:2136-2143
مصطلحات موضوعية: 0301 basic medicine, Intracerebral hemorrhage, Biodistribution, Pharmaceutical Science, Plasma protein binding, 030204 cardiovascular system & hematology, Pharmacology, Biology, medicine.disease, law.invention, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Pharmacokinetics, Coagulation, law, Pharmacodynamics, medicine, Recombinant DNA, Distribution (pharmacology)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::aa0aa25dfea0ee3ee0f2b82522f66191
https://doi.org/10.1016/j.xphs.2017.03.035 -
10
المؤلفون: Leslie G. Lorello, Jim McNally, Hugh D. Conlon, Michael W. Leach, Carol F. Kirchhoff, Teresa Annette Smolarek, Andrew Saati, Sarah Koob, Mazin Derzi, Ahmed M. Shoieb, Penny Sharpe, Michael W. Bolt, Theodore R. Johnson
المصدر: Advances in Therapy
مصطلحات موضوعية: Monoclonal antibody, Male, 0301 basic medicine, Tumor necrosis factor, medicine.drug_class, Pharmacology toxicology, Drug Evaluation, Preclinical, Remicade, Pharmacology, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, medicine, Animals, Pharmacology (medical), Biosimilar Pharmaceuticals, Original Research, Medicine(all), 030203 arthritis & rheumatology, Toxicity, Tumor Necrosis Factor-alpha, business.industry, Biosimilar, Antibodies, Monoclonal, General Medicine, Infliximab, Toxicokinetics, Rats, Human tumor, Treatment Outcome, 030104 developmental biology, Liver, Immunology, Administration, Intravenous, Tumor necrosis factor alpha, business, Immunosuppressive Agents, medicine.drug