نتائج البحث - "Michelle C. Bradley"

المساهمون: Fazakerley, Daniel J [0000-0001-8241-2903], Tumanov, Sergey [0000-0002-0557-3153], Apollo - University of Cambridge Repository, Fazakerley, Daniel [0000-0001-8241-2903]

المصدر: Redox Biology
Redox Biology, Vol 46, Iss, Pp 102127-(2021)

مصطلحات موضوعية: Medicine (General), S-Adenosylmethionine, Mitochondrial Diseases, Ubiquinone, Phosphatidylethanolamine N-Methyltransferase, Clinical Biochemistry, Mitochondrion, Medical Biochemistry and Metabolomics, medicine.disease_cause, Biochemistry, chemistry.chemical_compound, Mice, Biology (General), Phospholipids, chemistry.chemical_classification, 0303 health sciences, Chemistry, 030302 biochemistry & molecular biology, food and beverages, Pharmacology and Pharmaceutical Sciences, 3. Good health, Cell biology, Mitochondria, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Oxidation-Reduction, Research Paper, QH301-705.5, S-adenosylhomocysteine, 03 medical and health sciences, R5-920, Metabolomics, PEMT, Biosynthesis, Lipidomics, medicine, Genetics, Animals, Genetic Testing, Metabolic and endocrine, 030304 developmental biology, Nutrition, Phosphatidylethanolamine, Reactive oxygen species, S-adenosylmethionine, Organic Chemistry, Coenzyme Q, Insulin resistance, Pemt, Coenzyme Q – cytochrome c reductase, Biochemistry and Cell Biology, Oxidative stress

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a42dc8296c2423f7fa00c428c954af
https://escholarship.org/uc/item/2vq9169s

6

COQ11 deletion mitigates respiratory deficiency caused by mutations in the gene encoding the coenzyme Q chaperone protein Coq10

المؤلفون: Michelle C. Bradley, Krista Yang, Anita Ayer, Noelle Alexa Novales, Roland Stocker, Hui S. Tsui, Mario H. Barros, Jennifer Ngo, Orian S. Shirihai, Catherine F. Clarke, Lucía Fernández-del-Río

المصدر: J Biol Chem
The Journal of biological chemistry, vol 295, iss 18

مصطلحات موضوعية: 0301 basic medicine, Biochemistry & Molecular Biology, Saccharomyces cerevisiae Proteins, mitochondrial metabolism, Ubiquinone, Mutant, Saccharomyces cerevisiae, CoQ synthome, Coq10, yeast, Biochemistry, Medical and Health Sciences, Coq11, Lipid peroxidation, 03 medical and health sciences, chemistry.chemical_compound, Gene Knockout Techniques, Biosynthesis, lipid, Complementary and Integrative Health, Genetics, Humans, Molecular Biology, Nutrition, 030102 biochemistry & molecular biology, biology, Cell Biology, Biological Sciences, biology.organism_classification, Yeast, Cell biology, Mitochondria, Metabolic pathway, Protein Transport, 030104 developmental biology, Fungal, Metabolism, chemistry, Gene Expression Regulation, Chaperone (protein), Coenzyme Q – cytochrome c reductase, Chemical Sciences, biology.protein, Generic health relevance, coenzyme Q, Gene Deletion

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6edda1d3095fff542b3e1c31543ba60
https://europepmc.org/articles/PMC7196636/

7

Intragenic suppressor mutations of the COQ8 protein kinase homolog restore coenzyme Q biosynthesis and function in Saccharomyces cerevisiae

المؤلفون: Nguyen V. Pham, Juan Nathaniel, Anish Nag, Catherine F. Clarke, Michelle C. Bradley, Nour Jabassini, Agape M. Awad

المساهمون: Lustig, Arthur J

المصدر: PloS one, vol 15, iss 6
PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0234192 (2020)

مصطلحات موضوعية: Protein Conformation, Ubiquinone, Mutant, Yeast and Fungal Models, Biochemistry, Protein structure, Suppression, Genetic, Gene Expression Regulation, Fungal, Energy-Producing Organelles, Multidisciplinary, biology, Chemistry, Eukaryota, Lipids, Cell biology, Mitochondria, Enzymes, Fungal, Experimental Organism Systems, Medicine, Asparagine, Cellular Structures and Organelles, Research Article, Saccharomyces cerevisiae Proteins, General Science & Technology, Science, Saccharomyces cerevisiae, Bioenergetics, Research and Analysis Methods, Biosynthesis, Cofactor, Saccharomyces, Model Organisms, Genetic, Genetics, Point Mutation, Protein kinase A, Suppressor mutation, Suppression, Point mutation, Organisms, Fungi, Biology and Life Sciences, Polypeptides, Proteins, Cell Biology, biology.organism_classification, Yeast, Culture Media, Gene Expression Regulation, Amino Acid Substitution, Coenzyme Q – cytochrome c reductase, Mutation, biology.protein, Animal Studies, Enzymology, Generic health relevance, Peptides, Protein Kinases

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d377b4df67650bfce1ec375aa6081b
https://escholarship.org/uc/item/8rv6r0s6

8

Coenzyme Q10 deficiencies: pathways in yeast and humans

المؤلفون: Anish Nag, Agape M. Awad, Lucía Fernández-del-Río, Catherine F. Clarke, Michelle C. Bradley, Hui S. Tsui

المصدر: Essays in Biochemistry. 62:361-376

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a6eb1c50f55775115bc6462bfac21664
https://doi.org/10.1042/ebc20170106

9

Chromatin-remodeling SWI/SNF complex regulates coenzyme Q6 synthesis and a metabolic shift to respiration in yeast

المؤلفون: Lauren T. Neves, Srivats Venkataramanan, Agape M. Awad, Catherine F. Clarke, Stephen Douglass, Anoop R. Galivanche, Anish Nag, Michelle C. Bradley, Tracy L. Johnson

المصدر: The Journal of biological chemistry, vol 292, iss 36

مصطلحات موضوعية: 0301 basic medicine, Biochemistry & Molecular Biology, Spliceosome, mitochondrial metabolism, Saccharomyces cerevisiae Proteins, Ubiquinone, 1.1 Normal biological development and functioning, RNA Splicing, Saccharomyces cerevisiae, Biology, Medical and Health Sciences, Biochemistry, Chromatin remodeling, chromatin remodeling, alternative splicing, 03 medical and health sciences, Rare Diseases, Underpinning research, Protein splicing, lipid metabolism, Genetics, Protein Phosphatase 2, Molecular Biology, Adenosine Triphosphatases, 030102 biochemistry & molecular biology, SWI/SNF complex, phosphorylation, Human Genome, Alternative splicing, Cell Biology, Biological Sciences, Chromatin, SWI/SNF, Metabolism, 030104 developmental biology, Chemical Sciences, RNA splicing, gene expression, metabolic regulation, Generic health relevance, coenzyme Q, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164c4bf79607ebefcb1246502879929e
https://doi.org/10.1074/jbc.m117.798397

10

Human COQ10A and COQ10B are distinct lipid-binding START domain proteins required for coenzyme Q function

المؤلفون: Brendan R. Amer, Robert T. Clubb, Jason E. Gosschalk, Marcus Gallagher-Jones, Catherine F. Clarke, Crysten E. Blaby-Haas, Hope Ibarra, Nguyen V. Pham, Michelle C. Bradley, Hui S. Tsui

المصدر: Journal of lipid research, vol 60, iss 7
J Lipid Res
Journal of Lipid Research, Vol 60, Iss 7, Pp 1293-1310 (2019)

مصطلحات موضوعية: 0301 basic medicine, Mitochondrial Diseases, Ubiquinone, Mutant, 030204 cardiovascular system & hematology, Mitochondrion, Medical Biochemistry and Metabolomics, Biochemistry, Antioxidants, Mass Spectrometry, 0302 clinical medicine, Endocrinology, Proton transport, Research Articles, Muscle Weakness, biology, Chemistry, lipids/chemistry, food and beverages, steroidogenic acute regulatory protein-related lipid transfer, Cell biology, Mitochondria, Biochemistry & Molecular Biology, Saccharomyces cerevisiae Proteins, 1.1 Normal biological development and functioning, Saccharomyces cerevisiae, Protein domain, QD415-436, chemistry, lipids, 03 medical and health sciences, Underpinning research, Complementary and Integrative Health, Genetics, Humans, Nutrition, Cell Biology, biology.organism_classification, Phosphoproteins, Yeast, peroxidation, Oxidative Stress, 030104 developmental biology, lipids/peroxidation, Chaperone (protein), Coenzyme Q – cytochrome c reductase, biology.protein, Ataxia, Lipid Peroxidation, Generic health relevance, Biochemistry and Cell Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e36324d15742dd2fe9a7b3a36f611f
https://escholarship.org/uc/item/3qx9m140

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