المؤلفون: Eshita Khera, Cornelius Cilliers, Michael D. Smith, Michelle L. Ganno, Katharine C. Lai, Thomas A. Keating, Anna Kopp, Ian Nessler, Adnan O. Abu-Yousif, Greg M. Thurber

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 2, Pp 210-221 (2021)

مصطلحات موضوعية: ADC bystander effect, Pharmacodynamic marker, Primary human tumor xenograft, Tumor-associated macrophages, Tumor spheroids, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558620301822; https://doaj.org/toc/1476-5586

URL الوصول: https://doaj.org/article/a1d49a829b1446a5941d3e371fc652ef

المؤلفون: Jay P. McLaughlin, Ramanjaneyulu Rayala, Ashley J. Bunnell, Mukund P. Tantak, Shainnel O. Eans, Khadija Nefzi, Michelle L. Ganno, Colette T. Dooley, Adel Nefzi

المصدر: International Journal of Molecular Sciences, Vol 23, Iss 17, p 9623 (2022)

مصطلحات موضوعية: heterocyclic peptidomimetics, combinatorial chemistry, solid-phase synthesis, opioid receptors, multifunctional opioid agonist, antinociception, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/23/17/9623; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/048103fa04c04e789073971b3b5c242c

المؤلفون: Ariana C. Brice-Tutt, Sanjeewa N. Senadheera, Michelle L. Ganno, Shainnel O. Eans, Tanvir Khaliq, Thomas F. Murray, Jay P. McLaughlin, Jane V. Aldrich

المصدر: Molecules, Vol 25, Iss 17, p 3999 (2020)

مصطلحات موضوعية: opioid peptide, macrocyclic tetrapeptide, multifunctional ligands, structure-activity relationships, kappa opioid receptor, delta opioid receptor, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/17/3999; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/017a586349384007872af65cadb6d478

المؤلفون: O. Petter Veiby, Jennifer Fretland, Mark G. Qian, Jayaprakasam Bolleddula, Robbie Robertson, Maria Borland, Melissa Saylor Landen, Cindy Q. Xia, Andy Zhu, Secil Koseoglu, Kurt Eng, Afrand Kamali, Bradley Stringer, Thomas A. Keating, Katharine C. Lai, Michael D. Smith, Michelle L. Ganno, Bret M. Bannerman, Melissa Gallery, Donna Cvet, Adnan O. Abu-Yousif

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e7d56b0bf0e605a39ee70fc897c8b59
https://doi.org/10.1158/1535-7163.c.6542328.v1

المؤلفون: O. Petter Veiby, Jennifer Fretland, Mark G. Qian, Jayaprakasam Bolleddula, Robbie Robertson, Maria Borland, Melissa Saylor Landen, Cindy Q. Xia, Andy Zhu, Secil Koseoglu, Kurt Eng, Afrand Kamali, Bradley Stringer, Thomas A. Keating, Katharine C. Lai, Michael D. Smith, Michelle L. Ganno, Bret M. Bannerman, Melissa Gallery, Donna Cvet, Adnan O. Abu-Yousif

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc671e1a3ed72f6591ec22f46838181
https://doi.org/10.1158/1535-7163.22519161.v1

المؤلفون: Bruna Menezes, Eshita Khera, Melissa Calopiz, Michael D. Smith, Michelle L. Ganno, Cornelius Cilliers, Adnan O. Abu-Yousif, Jennifer J. Linderman, Greg M. Thurber

المصدر: The AAPS journal. 24(6)

مصطلحات موضوعية: Mice, Immunoconjugates, Cell Line, Tumor, Neoplasms, Pharmaceutical Science, Animals, Humans, Antineoplastic Agents, Bystander Effect, Antibodies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a066e9740ddf37500bec545b3a18358
https://pubmed.ncbi.nlm.nih.gov/36207468

المؤلفون: Katharine C. Lai, Michael D. Smith, Ian Nessler, Anna Kopp, Cornelius Cilliers, Thomas A. Keating, Adnan O. Abu-Yousif, Greg M. Thurber, Michelle L. Ganno, Eshita Khera

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 2, Pp 210-221 (2021)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Immunoconjugates, Cell, Fluorescent Antibody Technique, Mice, Antineoplastic Agents, Immunological, 0302 clinical medicine, Tumor Microenvironment, Bystander effect, Primary human tumor xenograft, biology, Chemistry, Tumor-associated macrophages, PHTX, primary human tumor xenograft, MTD, maximum tolerated dose, ADC bystander effect, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Female, Drug Monitoring, Antibody, Original article, Pharmacodynamic marker, PBS, phosphate-buffered saline, Mice, Transgenic, lcsh:RC254-282, TAM, tumor-associated macrophages, 03 medical and health sciences, Antigen, GCC, guanylyl-cyclase C, Cell Line, Tumor, medicine, Animals, Humans, Tumor microenvironment, Payload, Bystander Effect, SBE, spatial bystander effects, Penetration (firestop), Xenograft Model Antitumor Assays, Immunoglobulin Fc Fragments, Disease Models, Animal, ADCs, antibody drug conjugates, 030104 developmental biology, Cell culture, biology.protein, Cancer research, Tumor spheroids, BSA, bovine serum albumin, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303ee4292d185874883a1e4516940339
https://doi.org/10.1016/j.neo.2020.12.001

المؤلفون: Bradley Stringer, Kurt Eng, Katharine C. Lai, Mark G. Qian, Jennifer Fretland, Melissa Gallery, Robbie Robertson, Melissa Saylor Landen, Cindy Q. Xia, Adnan O. Abu-Yousif, O. Petter Veiby, Afrand Kamali, Maria Borland, Secil Koseoglu, Bret Bannerman, Andy Z. X. Zhu, Michelle L. Ganno, Thomas A. Keating, Michael D. Smith, Donna Cvet, Jayaprakasam Bolleddula

المصدر: Molecular Cancer Therapeutics. 19:2079-2088

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Biodistribution, Immunoconjugates, medicine.drug_class, Mice, Nude, Monoclonal antibody, Mice, 03 medical and health sciences, 0302 clinical medicine, In vivo, medicine, Animals, Humans, Cytotoxic T cell, Tissue Distribution, Tight junction, Chemistry, Guanylate cyclase 2C, Xenograft Model Antitumor Assays, In vitro, HEK293 Cells, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Female, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36fad95085a4edda953eff31247a4c7
https://doi.org/10.1158/1535-7163.mct-19-1102

المؤلفون: Vicky A. Appleman, Allison J. Berger, Emily R. Roberts, Angel E. Maldonado-Lopez, Michelle L. Ganno, Camilla I. Christensen, Tiquella Hatten, Yosuke Sato, Michael H. Shaw, Karim S. Malek, Neil B. Lineberry, Adnan O. Abu-Yousif, Richard C. Gregory

المصدر: Cancer Research. 82:3448-3448

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::791e47ed83283036773eb7b90ab2fc29
https://doi.org/10.1158/1538-7445.am2022-3448

المؤلفون: Thomas F. Murray, Jay P. McLaughlin, Sanjeewa N. Senadheera, Shainnel O. Eans, Ariana C. Brice-Tutt, Tanvir Khaliq, Jane V. Aldrich, Michelle L. Ganno

المصدر: Molecules
Volume 25
Issue 17
Molecules, Vol 25, Iss 3999, p 3999 (2020)

مصطلحات موضوعية: medicine.drug_class, Narcotic Antagonists, Phenylalanine, Pharmaceutical Science, Pharmacology, Motor Activity, multifunctional ligands, κ-opioid receptor, Peptides, Cyclic, Article, Analytical Chemistry, lcsh:QD241-441, δ-opioid receptor, 03 medical and health sciences, 0302 clinical medicine, lcsh:Organic chemistry, Opioid receptor, Drug Discovery, opioid peptide, medicine, Radioligand, Animals, Physical and Theoretical Chemistry, kappa opioid receptor, Opioid peptide, 030304 developmental biology, 0303 health sciences, Tetrapeptide, Chemistry, opioid liabilities, Organic Chemistry, structure-activity relationships, Stereoisomerism, Conditioned place preference, Analgesics, Opioid, Mice, Inbred C57BL, Opioid, macrocyclic tetrapeptide, Chemistry (miscellaneous), delta opioid receptor, Receptors, Opioid, analgesics, Molecular Medicine, 030217 neurology & neurosurgery, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34dae573d777f9c215bb540af03a3919