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1
المؤلفون: Mireille Cartier, Gerhard G. Steinmann, George Kukolj, Jerry O. Stern, Kristi L. Berger, Joseph Scherer, Wulf O. Böcher, Marie-Josée Massariol, Yakov Datsenko, Ibtissem Triki, Martin Marquis
المصدر: Antimicrobial Agents and Chemotherapy. 58:698-705
مصطلحات موضوعية: Aminoisobutyric Acids, Genotype, Proline, Hepatitis C virus, Hepacivirus, Population, Gene Expression, Viral Nonstructural Proteins, medicine.disease_cause, Antiviral Agents, Leucine, Drug Resistance, Viral, medicine, Humans, Protease Inhibitors, Pharmacology (medical), Protease inhibitor (pharmacology), education, Pharmacology, Clinical Trials as Topic, education.field_of_study, NS3, Polymorphism, Genetic, biology, Hepatitis C, Hepatitis C, Chronic, biology.organism_classification, medicine.disease, Virology, Thiazoles, Infectious Diseases, Amino Acid Substitution, Mutation, Faldaprevir, Quinolines, Drug Monitoring, Oligopeptides
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3cf07fb110ae329652da0f0c543634
https://doi.org/10.1128/aac.01976-13 -
2
المؤلفون: Frédéric H. Vaillancourt, George Kukolj, Richard Bethell, Louise Pilote, Michael G. Cordingley, Mireille Cartier, Michel Liuzzi, Julie Lippens
المصدر: Virology. 387:5-10
مصطلحات موضوعية: Gene Expression Regulation, Viral, viruses, Hepatitis C virus, RNA-dependent RNA polymerase, Genome, Viral, Hepacivirus, Biology, Virus Replication, medicine.disease_cause, Adenoviridae, Minor Histocompatibility Antigens, Small hairpin RNA, Cell Line, Tumor, Virology, Gene Knockdown Techniques, medicine, Humans, Replicon, RNA, Small Interfering, Gene Library, siRNA screen, Lipid kinase, Gene knockdown, Host–pathogen interaction, Reproducibility of Results, virus diseases, Hepatitis C, Molecular biology, NS2-3 protease, Phosphotransferases (Alcohol Group Acceptor), Viral replication, RNA, Viral, PI4KA
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3
المؤلفون: Mireille Cartier, Jean Rancourt, Anne-Marie Faucher, Marie-Josée Massariol, Peter W. White, Ewald Welchner, Jacques Archambault
المصدر: Antimicrobial Agents and Chemotherapy. 49:4834-4842
مصطلحات موضوعية: medicine.drug_class, ATPase, Allosteric regulation, Acetates, Antiviral Agents, Structure-Activity Relationship, Adenosine Triphosphate, Allosteric Regulation, medicine, Humans, Pharmacology (medical), Sulfones, Enzyme Inhibitors, Tyrosine, Papillomaviridae, Pharmacology, chemistry.chemical_classification, biology, Drug discovery, Hydrolysis, Biphenyl Compounds, Helicase, Oncogene Proteins, Viral, Infectious Diseases, Enzyme, Mechanism of action, Biochemistry, chemistry, biology.protein, medicine.symptom, Antiviral drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e67b29ad5296c5386f393cb4b329524
https://doi.org/10.1128/aac.49.12.4834-4842.2005 -
4
المؤلفون: Florence Dô, Gordon Bolger, Michel Liuzzi, Mireille Cartier, Gulrez Fazal, Jean Rancourt, Stephen W. Mason, Lynne Lamarre, Serge Landry, Josée Bordeleau, Paul Whitehead, Robert S. McCollum, Yvon Gaudette, Erika Scouten, Nathalie Dansereau, Bruno Simoneau, Nicole Lapeyre, Carole Lawetz, Marie-Josée Massariol, Lisette Lagacé
المصدر: Journal of Virology. 79:13105-13115
مصطلحات موضوعية: RNA Caps, viruses, Molecular Sequence Data, Immunology, Respiratory Syncytial Virus Infections, Virus Replication, Microbiology, Virus, Inhibitory Concentration 50, Mice, chemistry.chemical_compound, Catalytic Domain, Virology, RNA polymerase, Vaccines and Antiviral Agents, Animals, Amino Acid Sequence, RNA, Messenger, Enzyme Inhibitors, Administration, Intranasal, Polymerase, Subgenomic mRNA, Mice, Inbred BALB C, Messenger RNA, biology, virus diseases, RNA, respiratory system, RNA-Dependent RNA Polymerase, Reverse transcriptase, Respiratory Syncytial Viruses, Ribonucleoproteins, chemistry, Viral replication, Drug Design, Insect Science, biology.protein, Sequence Alignment
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2be81f11f22390bf40b4d0626edd700
https://doi.org/10.1128/jvi.79.20.13105-13115.2005 -
5
المؤلفون: Bruno Simoneau, Nathalie Goudreau, Steven M. Weldon, Mireille Cartier, Marc-André Poupart, Jean Rancourt, Gerhard G. Steinmann, Pierre R. Bonneau, Roger St. George, Chan-Loi Yong, Gordon Bolger, Murray D. Bailey, Lisette Lagacé, Anne-Marie Faucher, Daniel Lamarre, Michael G. Cordingley, Roel E. Sentjens, Pierre L. Beaulieu, Diane Thibeault, Hans Narjes, Youla S. Tsantrizos, Steven R. LaPlante, Stephen H. Kawai, Paul C. Anderson, Montse Llinas-Brunet, Michael Bös, Dale R. Cameron, George Kukolj
المصدر: Nature. 426:186-189
مصطلحات موضوعية: Male, Macrocyclic Compounds, Serine Proteinase Inhibitors, Hepatitis C virus, Hepacivirus, Administration, Oral, Viral Nonstructural Proteins, medicine.disease_cause, Antiviral Agents, Virus, Viral Proteins, Double-Blind Method, Interferon, medicine, Humans, Protease inhibitor (pharmacology), Polyproteins, NS3, Multidisciplinary, biology, Danoprevir, virus diseases, Viral Load, biology.organism_classification, Hepatitis C, Virology, digestive system diseases, Thiazoles, Immunology, Quinolines, Carbamates, Protein Processing, Post-Translational, Viral load, medicine.drug
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6دورية أكاديمية
المؤلفون: Daniel Lamarre, Paul C. Anderson, Murray Bailey, Pierre Beaulieu, Gordon Bolger, Pierre Bonneau, Michael Bös, Dale R. Cameron, Mireille Cartier, Michael G. Cordingley, Anne-Marie Faucher, N
المصدر: Nature, Nature. 426(6963):186-189
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7
المؤلفون: Anil Kumar Padyana, Xiang Li, Asitha Abeywardane, Pierre R. Bonneau, René Coulombe, Qiang Zhang, Araz Jakalian, Steven John Taylor, Peter W. White, Steven R. LaPlante, Shuang Liang, Ginette McKercher, Jessi Wildeson-Jones, Mireille Cartier
المصدر: Journal of medicinal chemistry. 57(5)
مصطلحات موضوعية: Drug, Models, Molecular, Magnetic Resonance Spectroscopy, media_common.quotation_subject, Hepatitis C virus, In silico, Computational biology, Hepacivirus, Viral Nonstructural Proteins, Ns3 helicase, medicine.disease_cause, Antiviral Agents, Structure-Activity Relationship, Drug Discovery, medicine, Enzyme Inhibitors, media_common, biology, Drug discovery, Serine Endopeptidases, Helicase, Surface Plasmon Resonance, Virology, Kinetics, biology.protein, Molecular Medicine, RNA Helicases
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8
المؤلفون: Sherry Zhang, Grace K. Dahmus, Guohua Pan, Michael E. Dahmus, Jacques Archambault, Mireille Cartier, Jack Greenblatt, Nicholas F. Marshall
المصدر: Journal of Biological Chemistry. 273:27593-27601
مصطلحات موضوعية: Transcription, Genetic, Molecular Sequence Data, RNA-dependent RNA polymerase, RNA polymerase II, Saccharomyces cerevisiae, Biochemistry, Transcription Factors, TFII, chemistry.chemical_compound, RNA polymerase, Phosphoprotein Phosphatases, RNA polymerase I, Humans, Amino Acid Sequence, Cloning, Molecular, Molecular Biology, RNA polymerase II holoenzyme, Polymerase, Binding Sites, biology, Sequence Analysis, DNA, Cell Biology, chemistry, biology.protein, RNA Polymerase II, Transcription factor II D, Holoenzymes, Small nuclear RNA, Protein Binding, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7a700fc240fa8a0f1834836bc97261
https://doi.org/10.1074/jbc.273.42.27593 -
9
المؤلفون: Yuen Ho, Caroline M. Kane, Ross Chambers, Jack Greenblatt, Michael S. Kobor, Mireille Cartier, Brenda J. Andrews, Diana Bolotin, Jacques Archambault
المصدر: Proceedings of the National Academy of Sciences. 94:14300-14305
مصطلحات موضوعية: Multidisciplinary, biology, General transcription factor, Molecular Sequence Data, Saccharomyces cerevisiae, RNA polymerase II, Biological Sciences, biology.organism_classification, Phosphoric Monoester Hydrolases, Fungal Proteins, Transcription Factors, TFII, Biochemistry, TAF4, TAF2, Phosphoprotein Phosphatases, biology.protein, Transcription factor II F, Amino Acid Sequence, RNA Polymerase II, CTD phosphatase activity, Sequence Analysis, Transcription Factors, Binding domain
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7caede03a1e950260cf58f6807eede72
https://doi.org/10.1073/pnas.94.26.14300 -
10
المؤلفون: George Kukolj, Joseph Scherer, Lisette Lagacé, Carol Lawetz, Martin Marquis, Mireille Cartier, Kristi L. Berger, Richard Bethell, Ibtissem Triki
المصدر: Antimicrobial agents and chemotherapy. 57(10)
مصطلحات موضوعية: Aminoisobutyric Acids, Genotype, Genotyping Techniques, Proline, medicine.medical_treatment, viruses, Hepacivirus, Biology, Viral Nonstructural Proteins, Antiviral Agents, Virus, Cell Line, chemistry.chemical_compound, Leucine, medicine, Humans, Pharmacology (medical), Protease Inhibitors, Genotyping, Pharmacology, NS3, Protease, Ribavirin, virus diseases, Virology, Thiazoles, Infectious Diseases, chemistry, Faldaprevir, Quinolines, Viral load, Oligopeptides
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830d7f7bf9093daa4894bedb982d1738
https://pubmed.ncbi.nlm.nih.gov/23877706