المؤلفون: Khalek IS; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI, New York, NY 10004, USA., Senji Laxme RR; IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA.; Evolutionary Venomics Lab, Centre for Ecological Sciences, Indian Institute of Science, Bangalore 560012, Karnataka, India., Nguyen YTK; Department of Integrative Structural and Computational Biology, Scripps Research Institute, La Jolla, CA 92037, USA., Khochare S; Evolutionary Venomics Lab, Centre for Ecological Sciences, Indian Institute of Science, Bangalore 560012, Karnataka, India., Patel RN; Centre for Snakebite Research & Interventions, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK., Woehl J; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI, New York, NY 10004, USA., Smith JM; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI, New York, NY 10004, USA., Saye-Francisco K; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA., Kim Y; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI, New York, NY 10004, USA., Misson Mindrebo L; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI, New York, NY 10004, USA., Tran Q; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI, New York, NY 10004, USA., Kędzior M; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI, New York, NY 10004, USA., Boré E; Centre for Snakebite Research & Interventions, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK., Limbo O; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI, New York, NY 10004, USA., Verma M; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI, New York, NY 10004, USA., Stanfield RL; Department of Integrative Structural and Computational Biology, Scripps Research Institute, La Jolla, CA 92037, USA., Menzies SK; Centre for Snakebite Research & Interventions, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK., Ainsworth S; Centre for Snakebite Research & Interventions, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK., Harrison RA; Centre for Snakebite Research & Interventions, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK., Burton DR; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA.; Consortium for HIV/AIDS Vaccine Development (CHAVD), Scripps Research Institute, La Jolla, CA 92037, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02139, USA., Sok D; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI, New York, NY 10004, USA.; Consortium for HIV/AIDS Vaccine Development (CHAVD), Scripps Research Institute, La Jolla, CA 92037, USA., Wilson IA; Department of Integrative Structural and Computational Biology, Scripps Research Institute, La Jolla, CA 92037, USA.; Skaggs Institute for Chemical Biology, Scripps Research Institute, La Jolla, CA 92037, USA., Casewell NR; Centre for Snakebite Research & Interventions, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK., Sunagar K; Evolutionary Venomics Lab, Centre for Ecological Sciences, Indian Institute of Science, Bangalore 560012, Karnataka, India., Jardine JG; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI, New York, NY 10004, USA.

المصدر: Science translational medicine [Sci Transl Med] 2024 Feb 21; Vol. 16 (735), pp. eadk1867. Date of Electronic Publication: 2024 Feb 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Antivenins*/chemistry , Snake Bites*/drug therapy, Humans ; Animals ; Mice ; Neurotoxins/toxicity ; Broadly Neutralizing Antibodies ; Snake Venoms

المؤلفون: Misson Mindrebo L; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; International AIDS Vaccine Initiative, New York, NY 10004., Liu H; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037., Ozorowski G; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037., Tran Q; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; International AIDS Vaccine Initiative, New York, NY 10004., Woehl J; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; International AIDS Vaccine Initiative, New York, NY 10004., Khalek I; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; International AIDS Vaccine Initiative, New York, NY 10004., Smith JM; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; International AIDS Vaccine Initiative, New York, NY 10004., Barman S; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037.; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037., Zhao F; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037.; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037., Keating C; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037.; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037., Limbo O; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; International AIDS Vaccine Initiative, New York, NY 10004., Verma M; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; International AIDS Vaccine Initiative, New York, NY 10004., Liu J; Department of Bioengineering, Stanford University, Stanford, CA 94305., Stanfield RL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037., Zhu X; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037., Turner HL; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037., Sok D; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; International AIDS Vaccine Initiative, New York, NY 10004.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037.; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037., Huang PS; Department of Bioengineering, Stanford University, Stanford, CA 94305., Burton DR; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037.; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02139., Ward AB; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037., Wilson IA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037.; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037., Jardine JG; International AIDS Vaccine Initiative Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037.; International AIDS Vaccine Initiative, New York, NY 10004.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Jun 13; Vol. 120 (24), pp. e2216612120. Date of Electronic Publication: 2023 Jun 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Single-Domain Antibodies*/chemistry , COVID-19*, Humans ; Saccharomyces cerevisiae/metabolism ; SARS-CoV-2 ; Antibodies ; Epitopes

SCR Organism: SARS-CoV-2 variants