المؤلفون: Pantoja-Escobar, Gerardo, Morales-Martínez, Mario, Vega, Gabriel G, Castro-Escarpulli, Graciela, Vega, Mario I

المصدر: Leukemia & lymphoma. 60(4)

مصطلحات موضوعية: Antineoplastic Agents: chemistry, pharmacology, Apoptosis: drug effects, CD40 Antigens: metabolism, CD40 Ligand: chemistry, Caspases: metabolism, Cell Cycle: drug effects, Cell Line, Tumor, Cell Survival: drug effects, Humans, Molecular Mimicry, Peptides: chemistry, pharmacology, Porins: chemistry, Proto-Oncogene Proteins c-bcl-6: metabolism, YY1 Transcription Factor: metabolism, p38 Mitogen-Activated Protein Kinases: metabolism

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3nj9g30m

المؤلفون: Zhong, Jian, Gavrilescu, L Cristina, Molnár, Arpád, Murray, Lauren, Garafalo, Stephen, Kehrl, John H, Simon, Amy R, Van Etten, Richard A, Kyriakis, John M

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 106(11)

مصطلحات موضوعية: Adrenomedullin: pharmacology, Animals, Bone Marrow Transplantation, Cytokines: metabolism, Extracellular Signal-Regulated MAP Kinases, Hematopoietic Stem Cells: metabolism, Inflammation: etiology, JNK Mitogen-Activated Protein Kinases: metabolism, Macrophages: metabolism, Mice, Mice, Knockout, NF-kappa B, Protein-Serine-Threonine Kinases: deficiency, physiology, Receptors, Pattern Recognition: metabolism, p38 Mitogen-Activated Protein Kinases: metabolism

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6bt8z08s

المؤلفون: Chen, Gang, Khalil, Nasreen

مصطلحات موضوعية: Animals, Antibodies: pharmacology, Asthma: metabolism, Blood Proteins: pharmacology, Cattle, Cell Division: drug effects, Cells, Cultured, Drug Synergism, Epidermal Growth Factor: immunology, metabolism, Extracellular Signal-Regulated MAP Kinases: metabolism, Fibroblast Growth Factor 2: immunology, metabolism, Insulin-Like Growth Factor I: immunology, metabolism, JNK Mitogen-Activated Protein Kinases: metabolism, MAP Kinase Signaling System: drug effects, physiology, Myocytes, Smooth Muscle: cytology, drug effects, enzymology, Phosphorylation: drug effects, Platelet-Derived Growth Factor: immunology, metabolism, Trachea: cytology, Transforming Growth Factor beta: metabolism, pharmacology, Transforming Growth Factor beta1, p38 Mitogen-Activated Protein Kinases: metabolism

URL الوصول: https://escholarship.org/uc/item/0bx747fn

المؤلفون: Million, Ryan P, Harakawa, Nari, Roumiantsev, Sergei, Varticovski, Lyuba, Van Etten, Richard A

المصدر: Molecular and cellular biology. 24(11)

مصطلحات موضوعية: Adaptor Proteins, Signal Transducing, Animals, Binding Sites, Cell Transformation, Neoplastic: genetics, metabolism, GRB2 Adaptor Protein, Leukemia: etiology, metabolism, Mice, Mitogen-Activated Protein Kinases: metabolism, Oncogene Proteins, Fusion: genetics, metabolism, Phosphatidylinositol 3-Kinases: metabolism, Protein Binding, Protein Structure, Tertiary, Protein-Tyrosine Kinases, Proteins: metabolism, Tyrosine: metabolism

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8xm3z9x2

المؤلفون: Keyse, Stephen M.

مصطلحات موضوعية: MAP Kinase Signaling System -- physiology., Mitogen-Activated Protein Kinases -- metabolism., Phosphoprotein Phosphatases., Phosphorylation.

المؤلفون: Li, S, Couvillon, A D, Brasher, B B, Van Etten, R A

المصدر: The EMBO journal. 20(23)

مصطلحات موضوعية: 3T3 Cells, Adaptor Proteins, Signal Transducing, Animals, Binding Sites, Blotting, Western, Cell Line, Cell Line, Transformed, DNA Mutational Analysis, Dose-Response Relationship, Drug, Down-Regulation, Enzyme Activation, Fibroblasts: metabolism, Fusion Proteins, bcr-abl: metabolism, GRB2 Adaptor Protein, Humans, JNK Mitogen-Activated Protein Kinases, K562 Cells, MAP Kinase Signaling System, Mass Spectrometry, Mice, Mitogen-Activated Protein Kinases: metabolism, Mutation, Peptide Mapping, Phosphopeptides: chemistry, Phosphorylation, Precipitin Tests, Protein Binding, Protein Structure, Tertiary, Proteins: metabolism, Receptor, Epidermal Growth Factor: metabolism, Signal Transduction, Son of Sevenless Protein, Drosophila: metabolism, Time Factors, Transfection, Transformation, Genetic, Tumor Cells, Cultured, Tyrosine: metabolism, ras Proteins: metabolism, src Homology Domains

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/71b8n11d

المؤلفون: Tue W. Kragstrup, Anne Sofie Sørensen, Mads Brüner, Søren Lomholt, Morten A Nielsen, Peter Schafer, Bent Deleuran

المصدر: Kragstrup, T W, Sørensen, A S, Brüner, M, Lomholt, S, Nielsen, M A, Schafer, P & Deleuran, B 2022, ' MAPK activated kinase 2 inhibition shifts the chemokine signature in arthritis synovial fluid mononuclear cells from CXCR3 to CXCR2 ', International Immunopharmacology, vol. 112, 109267, pp. 109267 . https://doi.org/10.1016/j.intimp.2022.109267

مصطلحات موضوعية: Kinase, Immunology, Synovial Fluid/chemistry, Anti-Inflammatory Agents, Hepatocyte Growth Factor/metabolism, Arthritis, Psoriatic/drug therapy, Ligands, Receptors, Interleukin-8B, Interleukin-12 Subunit p40/metabolism, Transforming Growth Factor beta, Synovial Fluid, Spondyloarthritis, Immunology and Allergy, Humans, Rheumatoid arthritis, Immune-mediated inflammatory arthritis, Cells, Cultured, Receptors, Interleukin-8B/metabolism, Pharmacology, Interleukin-12 Subunit p40, Hepatocyte Growth Factor, Arthritis, Psoriatic, Synovial Membrane, Small molecules, Transforming Growth Factor alpha, Synovial Membrane/metabolism, Anti-Inflammatory Agents/metabolism, Chemokines/metabolism, Transforming Growth Factor alpha/analysis, Psoriatic arthritis, Interferons, Mitogen-Activated Protein Kinases, Chemokines, Mitogen-Activated Protein Kinases/metabolism, Transforming Growth Factor beta/metabolism, Interferons/metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e54ab673193fa638c9316149fb2b88
https://pure.au.dk/portal/da/publications/mapk-activated-kinase-2-inhibition-shifts-the-chemokine-signature-in-arthritis-synovial-fluid-mononuclear-cells-from-cxcr3-to-cxcr2(e2c6ddf7-4075-4520-8be8-3cd04425cc32).html

المؤلفون: Edlund, Sofia, Lee, So Young, Grimsby, Susanne, Zhang, Shouthing, Aspenström, Pontus, Heldin, Carl-Henrik, Landström, Maréne

المصدر: Molecular and Cellular Biology. 25(4):1475-1488

مصطلحات موضوعية: Animals, Apoptosis/drug effects/*physiology, COS Cells, Cell Fractionation, Cercopithecus aethiops, Cytoskeletal Proteins/*metabolism, DNA-Binding Proteins/*metabolism, Glycogen Synthase Kinase 3/metabolism, Humans, Male, Mice, Phosphorylation/drug effects, Prostatic Neoplasms/metabolism, Protein Binding/drug effects, Protein-Serine-Threonine Kinases/metabolism, Proto-Oncogene Proteins/metabolism, RNA, Small Interfering/metabolism, Research Support, Non-U.S. Gov't, Serine/metabolism, Trans-Activators/*metabolism, Transcription Factors/*metabolism, Transforming Growth Factor beta/*pharmacology, Tumor Cells, Cultured, p38 Mitogen-Activated Protein Kinases/metabolism

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-72728
https://doi.org/10.1128/MCB.25.4.1475-1488.2005
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=15684397&dopt=Citation

المؤلفون: Piltti, Juha

المساهمون: Umeå universitet. Institutionen för integrativ medicinsk biologi

مصطلحات موضوعية: Rho-kinase inhibition, Y-27632, Hypoxia, Cyclic stretching, Human chondrosarcoma 2/8 cells, Chondrocyte phenotype, Fibroblasts, Proteomics, Protein pathway analytics, Amides -- pharmacology, Fibroblasts -- cytology, Protein kinase inhibitors -- pharmacology, Pyridines -- pharmacology, rho-associated kinases -- antagonists & inhibitors, Chondrocytes -- metabolism, Chondrosarcoma -- metabolism, Chondrosarcoma -- pathology, Mitogen-activated protein kinases -- metabolism, Peptide elongation factor 2 -- metabolism, Phosphoproteins -- metabolism, Proteomics

URL الوصول: http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-133851

Degree: Diss. (sammanfattning) Umeå : Umeå universitet, 2017

المؤلفون: Maria I. Kontaridis, Amy E. Roberts, Lisa Schill, Lisa Schoyer, Beth Stronach, Gregor Andelfinger, Yoko Aoki, Marni E. Axelrad, Annette Bakker, Anton M. Bennett, Alberto Broniscer, Pau Castel, Caitlin A. Chang, Lukas Cyganek, Tirtha K. Das, Jeroen Hertog, Emilia Galperin, Shruti Garg, Bruce D. Gelb, Kristiana Gordon, Tamar Green, Karen W. Gripp, Maxim Itkin, Maija Kiuru, Bruce R. Korf, Jeff R. Livingstone, Alejandro López‐Juárez, Pilar L. Magoulas, Sahar Mansour, Theresa Milner, Elisabeth Parker, Elizabeth I. Pierpont, Kevin Plouffe, Katherine A. Rauen, Suma P. Shankar, Shane B. Smith, David A. Stevenson, Marco Tartaglia, Richard Van, Morgan E. Wagner, Stephanie M. Ware, Martin Zenker

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: American journal of medical genetics. Part A, vol 188, iss 6
Kontaridis, M I, Roberts, A E, Schill, L, Schoyer, L, Stronach, B, Andelfinger, G, Aoki, Y, Axelrad, M E, Bakker, A, Bennett, A M, Broniscer, A, Castel, P, Chang, C A, Cyganek, L, Das, T K, den Hertog, J, Galperin, E, Garg, S, Gelb, B D, Gordon, K, Green, T, Gripp, K W, Itkin, M, Kiuru, M, Korf, B R, Livingstone, J R, López-Juárez, A, Magoulas, P L, Mansour, S, Milner, T, Parker, E, Pierpont, E I, Plouffe, K, Rauen, K A, Shankar, S P, Smith, S B, Stevenson, D A, Tartaglia, M, Van, R, Wagner, M E, Ware, S M & Zenker, M 2022, ' The seventh international RASopathies symposium : Pathways to a cure-expanding knowledge, enhancing research, and therapeutic discovery ', American Journal of Medical Genetics. Part A . https://doi.org/10.1002/ajmg.a.62716
American Journal of Medical Genetics, Part A, 188(6), 1915-1927. Wiley-Liss Inc.

مصطلحات موضوعية: Pediatric, neurofibromatosis, ras Proteins/genetics, Noonan Syndrome, Costello Syndrome, Clinical Sciences, cardiofaciocutaneus syndrome, Costello Syndrome/genetics, RASopathy, Good Health and Well Being, Noonan Syndrome/genetics, ras Proteins, Genetics, Humans, 2.1 Biological and endogenous factors, Mitogen-Activated Protein Kinases, Aetiology, Mitogen-Activated Protein Kinases/metabolism, signaling, Genetics (clinical), Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66770a599b697c0d77d007bd425f8e74
https://escholarship.org/uc/item/44s997fh