المؤلفون: Varghese S; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, 3052, Australia., Srivastava A; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, 3052, Australia., Wong SW; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, 3052, Australia., Le T; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, 3052, Australia., Pitcher N; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, 3052, Australia., Mesnard M; Ensemble Scientifique des Cézeaux, 24 avenue des Landais, 63170, Aubière, France., Lallemand C; Ensemble Scientifique des Cézeaux, 24 avenue des Landais, 63170, Aubière, France., Rahmani R; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, 3052, Australia., Moawad SR; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, Victoria, Australia., Huang F; School of Pharmaceutical Sciences, Nanjing Tech University, No. 30 South Puzhu Road, Nanjing, 211816, China., He T; School of Pharmaceutical Sciences, Nanjing Tech University, No. 30 South Puzhu Road, Nanjing, 211816, China., Sleebs BE; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, 3010, Australia., Barrett MP; Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Sykes ML; Discovery Biology, Centre for Cellular Phenomics, Griffith University, Nathan, Queensland, 4111, Australia., Avery VM; Discovery Biology, Centre for Cellular Phenomics, Griffith University, Nathan, Queensland, 4111, Australia; School of Environment and Science, Griffith University, Nathan, QLD, 4111, Australia., Creek DJ; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, 3052, Australia. Electronic address: darren.creek@monash.edu., Baell JB; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, 3052, Australia; School of Pharmaceutical Sciences, Nanjing Tech University, No. 30 South Puzhu Road, Nanjing, 211816, China. Electronic address: jonathan@lyterian.com.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2024 Mar 15; Vol. 268, pp. 116162. Date of Electronic Publication: 2024 Jan 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Trypanocidal Agents*/chemistry , Parasites* , Trypanosomiasis, African*/drug therapy , Trypanosomiasis, African*/parasitology , Trypanosoma* , Trypanosoma brucei brucei*, Animals ; Humans ; Trypanosoma brucei rhodesiense ; Guanidine/pharmacology ; Guanidines/pharmacology ; Energy Metabolism ; Mammals

المؤلفون: Sykes ML; Discovery Biology, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Nathan, Queensland, Australia., Baell JB, Kaiser M, Chatelain E, Moawad SR, Ganame D, Ioset JR, Avery VM

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2012; Vol. 6 (11), pp. e1896. Date of Electronic Publication: 2012 Nov 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Drug Evaluation, Preclinical/*methods , Trypanocidal Agents/*isolation & purification , Trypanosoma brucei brucei/*drug effects, Cell Line ; Cell Survival/drug effects ; High-Throughput Screening Assays/methods ; Humans ; Inhibitory Concentration 50 ; Microbial Viability/drug effects ; Oxazines/metabolism ; Staining and Labeling/methods ; Trypanosoma brucei brucei/physiology ; Xanthenes/metabolism