المؤلفون: Roboz GJ, Yee K, Verma A, Borthakur G, de la Fuente Burguera A, Sanz G, Mohammad HP, Kruger RG, Karpinich NO, Ferron-Brady G, Acusta A, Del Buono H, Collingwood T, Ballas M, Dhar A, Wei AH

المصدر: Leukemia & lymphoma
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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URL الوصول: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::e2923b92cf4577c43228ce6e5e3bac1e
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15262

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المؤلفون: seyed alireza sadr, aliasghar anvari rostami, Mohammad Hpssein Vadiee Noghabi

المصدر: راهبرد مدیریت مالی, Vol 2, Iss 3, Pp 1-25 (2014)

مصطلحات موضوعية: Finance, HG1-9999

وصف الملف: electronic resource

Relation: http://jfm.alzahra.ac.ir/article_987_d37a757cd7c51b9cd74a88a7852a1f7d.pdf; https://doaj.org/toc/2345-3214; https://doaj.org/toc/2538-1962

URL الوصول: https://doaj.org/article/a67521d159ca4e4eb5f23a736b8703a6

المؤلفون: Fedoriw A; Tumor Cell Targeting Research Unit, GlaxoSmithKline, Collegeville, Pennsylvania., Shi L; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., O'Brien S; Tumor Cell Targeting Research Unit, GlaxoSmithKline, Collegeville, Pennsylvania., Smitheman KN; Tumor Cell Targeting Research Unit, GlaxoSmithKline, Collegeville, Pennsylvania., Wang Y; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Hou J; Department of Biology and Biochemistry, University of Houston, Houston, Texas., Sherk C; Tumor Cell Targeting Research Unit, GlaxoSmithKline, Collegeville, Pennsylvania., Rajapurkar S; Tumor Cell Targeting Research Unit, GlaxoSmithKline, Collegeville, Pennsylvania., Laraio J; Tumor Cell Targeting Research Unit, GlaxoSmithKline, Collegeville, Pennsylvania., Williams LJ; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Xu C; Department of Biology and Biochemistry, University of Houston, Houston, Texas., Han G; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Feng Q; Department of Biology and Biochemistry, University of Houston, Houston, Texas., Bedford MT; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Smithville, Texas., Wang L; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Barbash O; Tumor Cell Targeting Research Unit, GlaxoSmithKline, Collegeville, Pennsylvania., Kruger RG; Tumor Cell Targeting Research Unit, GlaxoSmithKline, Collegeville, Pennsylvania., Hwu P; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Mohammad HP; Tumor Cell Targeting Research Unit, GlaxoSmithKline, Collegeville, Pennsylvania., Peng W; Department of Biology and Biochemistry, University of Houston, Houston, Texas.

المصدر: Cancer immunology research [Cancer Immunol Res] 2022 Apr 01; Vol. 10 (4), pp. 420-436.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE

مواضيع طبية MeSH: Intracellular Signaling Peptides and Proteins* , Protein-Arginine N-Methyltransferases*/genetics , Protein-Arginine N-Methyltransferases*/metabolism, Animals ; Arginine ; Humans ; Immunity ; Mice

المؤلفون: Pappalardi MB; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Keenan K; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Cockerill M; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Alderley Park, Macclesfield, UK.; These authors contributed equally: Mark Cockerill, Wendy A. Kellner., Kellner WA; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA.; These authors contributed equally: Mark Cockerill, Wendy A. Kellner., Stowell A; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Alderley Park, Macclesfield, UK., Sherk C; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Wong K; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Pathuri S; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Briand J; Medicinal Science & Technology, GlaxoSmithKline, Collegeville, PA, USA., Steidel M; Cellzome GmbH, Functional Genomics, GlaxoSmithKline, Heidelberg, Germany., Chapman P; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Alderley Park, Macclesfield, UK., Groy A; Future Pipeline Discovery, GlaxoSmithKline, Collegeville, PA, USA., Wiseman AK; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA., McHugh CF; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Campobasso N; Medicinal Science & Technology, GlaxoSmithKline, Collegeville, PA, USA., Graves AP; Medicinal Science & Technology, GlaxoSmithKline, Collegeville, PA, USA., Fairweather E; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Alderley Park, Macclesfield, UK., Werner T; Cellzome GmbH, Functional Genomics, GlaxoSmithKline, Heidelberg, Germany., Raoof A; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Alderley Park, Macclesfield, UK., Butlin RJ; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Alderley Park, Macclesfield, UK., Rueda L; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Horton JR; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Fosbenner DT; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Zhang C; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Handler JL; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Muliaditan M; Drug Metabolism and Pharmacokinetics Modelling, GlaxoSmithKline, Stevenage, UK., Mebrahtu M; Medicinal Science & Technology, GlaxoSmithKline, Collegeville, PA, USA., Jaworski JP; Medicinal Science & Technology, GlaxoSmithKline, Collegeville, PA, USA., McNulty DE; Medicinal Science & Technology, GlaxoSmithKline, Collegeville, PA, USA., Burt C; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Alderley Park, Macclesfield, UK., Eberl HC; Cellzome GmbH, Functional Genomics, GlaxoSmithKline, Heidelberg, Germany., Taylor AN; Medicinal Science & Technology, GlaxoSmithKline, Collegeville, PA, USA., Ho T; Medicinal Science & Technology, GlaxoSmithKline, Collegeville, PA, USA., Merrihew S; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Foley SW; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Rutkowska A; Cellzome GmbH, Functional Genomics, GlaxoSmithKline, Heidelberg, Germany., Li M; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Romeril SP; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Goldberg K; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Alderley Park, Macclesfield, UK., Zhang X; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kershaw CS; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Alderley Park, Macclesfield, UK., Bantscheff M; Cellzome GmbH, Functional Genomics, GlaxoSmithKline, Heidelberg, Germany., Jurewicz AJ; Medicinal Science & Technology, GlaxoSmithKline, Collegeville, PA, USA., Minthorn E; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Grandi P; Cellzome GmbH, Functional Genomics, GlaxoSmithKline, Heidelberg, Germany., Patel M; Medicinal Science & Technology, GlaxoSmithKline, Collegeville, PA, USA., Benowitz AB; Future Pipeline Discovery, GlaxoSmithKline, Collegeville, PA, USA., Mohammad HP; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Gilmartin AG; Future Pipeline Discovery, GlaxoSmithKline, Collegeville, PA, USA., Prinjha RK; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Ogilvie D; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Alderley Park, Macclesfield, UK., Carpenter C; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Heerding D; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Baylin SB; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA., Jones PA; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI, USA., Cheng X; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX, USA., King BW; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Luengo JI; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., Jordan AM; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Alderley Park, Macclesfield, UK., Waddell I; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Alderley Park, Macclesfield, UK., Kruger RG; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA., McCabe MT; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA, USA.

المصدر: Nature cancer [Nat Cancer] 2021 Oct; Vol. 2 (10), pp. 1002-1017. Date of Electronic Publication: 2021 Sep 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer

مواضيع طبية MeSH: Azacitidine*/pharmacology , Leukemia, Myeloid, Acute*/drug therapy, Animals ; DNA/metabolism ; DNA Methylation ; DNA Modification Methylases/genetics ; Decitabine/pharmacology ; Mice

المؤلفون: Noto PB; Experimental Medicine Unit, Oncology R&D, GSK, Collegeville, USA. paul.x.noto@gsk.com., Sikorski TW; Protein Mass Spectrometry, In Vitro/In Vivo Translation, Research, GSK, Collegeville, USA., Zappacosta F; Discovery Analytical, Medicinal Science and Technology, Research, GSK, Collegeville, USA., Wagner CD; Discovery Analytical, Medicinal Science and Technology, Research, GSK, Collegeville, USA., Montes de Oca R; Experimental Medicine Unit, Oncology R&D, GSK, Collegeville, USA., Szapacs ME; Protein Mass Spectrometry, In Vitro/In Vivo Translation, Research, GSK, Collegeville, USA., Annan RS; Discovery Analytical, Medicinal Science and Technology, Research, GSK, Collegeville, USA., Liu Y; Epigenetics, Oncology R&D, GSK, Collegeville, USA., McHugh CF; Discovery DMPK, In Vitro / In Vivo Translation, Research, GSK, Collegeville, USA., Mohammad HP; Epigenetics, Oncology R&D, GSK, Collegeville, USA., Piccoli SP; Experimental Medicine Unit, Oncology R&D, GSK, Collegeville, USA.; Clinical Biomarkers and Diagnostics, Sun Pharmaceutical Advanced Research Center (SPARC), Princeton, USA., Creasy CL; Epigenetics, Oncology R&D, GSK, Collegeville, USA.

المصدر: Scientific reports [Sci Rep] 2020 Dec 17; Vol. 10 (1), pp. 22155. Date of Electronic Publication: 2020 Dec 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Biomarkers*, Antineoplastic Agents/*pharmacokinetics , Heterogeneous Nuclear Ribonucleoprotein A1/*metabolism , Protein-Arginine N-Methyltransferases/*antagonists & inhibitors , Repressor Proteins/*antagonists & inhibitors, Animals ; Antineoplastic Agents/therapeutic use ; Antineoplastic Agents, Immunological/chemistry ; Antineoplastic Agents, Immunological/pharmacokinetics ; Antineoplastic Agents, Immunological/pharmacology ; Arginine/metabolism ; Cells, Cultured ; Chromatography, Liquid ; Drug Monitoring ; Enzyme Activation ; Enzyme Inhibitors/pharmacokinetics ; Enzyme Inhibitors/therapeutic use ; Gene Expression Regulation, Neoplastic/drug effects ; Heterogeneous Nuclear Ribonucleoprotein A1/blood ; Humans ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/metabolism ; Mass Spectrometry ; Methylation ; Mice ; Molecular Targeted Therapy ; Neoplasms/blood ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Protein-Arginine N-Methyltransferases/genetics ; Repressor Proteins/genetics ; Substrate Specificity

المؤلفون: Miller SA; Genome, Cell, and Developmental Biology, Department of Biology, Indiana University Bloomington, Bloomington, Indiana.; Medical Sciences Program, Indiana University School of Medicine, Bloomington, Indiana., Policastro RA; Genome, Cell, and Developmental Biology, Department of Biology, Indiana University Bloomington, Bloomington, Indiana., Savant SS; Medical Sciences Program, Indiana University School of Medicine, Bloomington, Indiana., Sriramkumar S; Medical Sciences Program, Indiana University School of Medicine, Bloomington, Indiana., Ding N; Medical Sciences Program, Indiana University School of Medicine, Bloomington, Indiana., Lu X; Center for Computational Biology and Bioinformatics, Department of Biostatistics, Indiana University School of Medicine, Indianapolis, Indiana.; Department of Biohealth Informatics, Indiana University-Purdue University, Indianapolis, Indiana., Mohammad HP; Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, Pennsylvania., Cao S; Department of Biohealth Informatics, Indiana University-Purdue University, Indianapolis, Indiana., Kalin JH; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts., Cole PA; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts., Zentner GE; Genome, Cell, and Developmental Biology, Department of Biology, Indiana University Bloomington, Bloomington, Indiana.; Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana., O'Hagan HM; Medical Sciences Program, Indiana University School of Medicine, Bloomington, Indiana. hmohagan@indiana.edu.; Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana.

المصدر: Molecular cancer research : MCR [Mol Cancer Res] 2020 Feb; Vol. 18 (2), pp. 264-277. Date of Electronic Publication: 2019 Nov 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3125 (Electronic) Linking ISSN: 15417786 NLM ISO Abbreviation: Mol Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Class I Phosphatidylinositol 3-Kinases/*genetics , Colorectal Neoplasms/*genetics , Colorectal Neoplasms/*metabolism , Histone Demethylases/*metabolism , Proto-Oncogene Proteins c-akt/*metabolism, Cell Line, Tumor ; Chromatin/genetics ; Chromatin/metabolism ; Class I Phosphatidylinositol 3-Kinases/metabolism ; Colorectal Neoplasms/pathology ; Epithelial-Mesenchymal Transition/genetics ; Gene Knockout Techniques ; HCT116 Cells ; HT29 Cells ; Histone Demethylases/genetics ; Humans ; Mutation ; Phosphorylation ; Protein Stability ; Proto-Oncogene Proteins c-akt/genetics ; Snail Family Transcription Factors/genetics ; Snail Family Transcription Factors/metabolism ; Transfection

المؤلفون: Bauer TM; Sarah Cannon Research Institute, Nashville, Tennessee; Tennessee Oncology, PLLC, Nashville, Tennessee., Besse B; Gustave-Roussy Cancer Campus, Cancer Medicine Department, Villejuif, France; Paris-Sud University, Orday, France., Martinez-Marti A; Vall d' Hebrón Institute of Oncology and University Hospital, Barcelona, Spain., Trigo JM; University Hospital Virgen de la Victoria, Málaga, Spain., Moreno V; START Madrid-FJD, Jiménez Díaz Foundation Hospital, Madrid, Spain., Garrido P; Ramón y Cajal University Hospital, IRYCIS, Alcalá University, Madrid, Spain., Ferron-Brady G; GlaxoSmithKline, Collegeville, Pennsylvania., Wu Y; GlaxoSmithKline, Collegeville, Pennsylvania., Park J; GlaxoSmithKline, Collegeville, Pennsylvania., Collingwood T; GlaxoSmithKline, Collegeville, Pennsylvania., Kruger RG; GlaxoSmithKline, Collegeville, Pennsylvania., Mohammad HP; GlaxoSmithKline, Collegeville, Pennsylvania., Ballas MS; GlaxoSmithKline, Collegeville, Pennsylvania., Dhar A; GlaxoSmithKline, Collegeville, Pennsylvania., Govindan R; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri. Electronic address: rgovindan@wustl.edu.

المصدر: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [J Thorac Oncol] 2019 Oct; Vol. 14 (10), pp. 1828-1838. Date of Electronic Publication: 2019 Jun 28.

نوع المنشور: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101274235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-1380 (Electronic) Linking ISSN: 15560864 NLM ISO Abbreviation: J Thorac Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Salvage Therapy*, Benzoates/*therapeutic use , Cyclopropanes/*therapeutic use , Drug Resistance, Neoplasm/*drug effects , Lung Neoplasms/*drug therapy , Neoplasm Recurrence, Local/*drug therapy , Small Cell Lung Carcinoma/*drug therapy, Adolescent ; Adult ; Aged ; Benzoates/pharmacokinetics ; Cyclopropanes/pharmacokinetics ; Dose-Response Relationship, Drug ; Female ; Follow-Up Studies ; Humans ; Lung Neoplasms/pathology ; Male ; Maximum Tolerated Dose ; Middle Aged ; Neoplasm Recurrence, Local/pathology ; Prognosis ; Small Cell Lung Carcinoma/pathology ; Survival Rate ; Tissue Distribution ; Young Adult

المؤلفون: Fedoriw A; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Rajapurkar SR; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., O'Brien S; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Gerhart SV; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Mitchell LH; Epizyme, Inc, Cambridge, MA 02139, USA., Adams ND; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Rioux N; Epizyme, Inc, Cambridge, MA 02139, USA., Lingaraj T; Epizyme, Inc, Cambridge, MA 02139, USA., Ribich SA; Epizyme, Inc, Cambridge, MA 02139, USA., Pappalardi MB; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Shah N; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Laraio J; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Liu Y; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Butticello M; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Carpenter CL; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Creasy C; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Korenchuk S; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., McCabe MT; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., McHugh CF; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Nagarajan R; Medicinal Science and Technology, GlaxoSmithKline, Collegeville, PA 19426, USA., Wagner C; Medicinal Science and Technology, GlaxoSmithKline, Collegeville, PA 19426, USA., Zappacosta F; Medicinal Science and Technology, GlaxoSmithKline, Collegeville, PA 19426, USA., Annan R; Medicinal Science and Technology, GlaxoSmithKline, Collegeville, PA 19426, USA., Concha NO; Medicinal Science and Technology, GlaxoSmithKline, Collegeville, PA 19426, USA., Thomas RA; Nonclinical Safety Assessment, GlaxoSmithKline, Collegeville, PA 19426, USA., Hart TK; Nonclinical Safety Assessment, GlaxoSmithKline, Collegeville, PA 19426, USA., Smith JJ; Epizyme, Inc, Cambridge, MA 02139, USA., Copeland RA; Epizyme, Inc, Cambridge, MA 02139, USA., Moyer MP; Epizyme, Inc, Cambridge, MA 02139, USA., Campbell J; Epizyme, Inc, Cambridge, MA 02139, USA., Stickland K; Epizyme, Inc, Cambridge, MA 02139, USA., Mills J; Epizyme, Inc, Cambridge, MA 02139, USA., Jacques-O'Hagan S; Epizyme, Inc, Cambridge, MA 02139, USA., Allain C; Epizyme, Inc, Cambridge, MA 02139, USA., Johnston D; Epizyme, Inc, Cambridge, MA 02139, USA., Raimondi A; Epizyme, Inc, Cambridge, MA 02139, USA., Porter Scott M; Epizyme, Inc, Cambridge, MA 02139, USA., Waters N; Epizyme, Inc, Cambridge, MA 02139, USA., Swinger K; Epizyme, Inc, Cambridge, MA 02139, USA., Boriack-Sjodin A; Epizyme, Inc, Cambridge, MA 02139, USA., Riera T; Epizyme, Inc, Cambridge, MA 02139, USA., Shapiro G; Epizyme, Inc, Cambridge, MA 02139, USA., Chesworth R; Epizyme, Inc, Cambridge, MA 02139, USA., Prinjha RK; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Kruger RG; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Barbash O; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA., Mohammad HP; Epigenetics Research Unit, GlaxoSmithKline, Collegeville, PA 19426, USA. Electronic address: helai.x.mohammad@gsk.com.

المصدر: Cancer cell [Cancer Cell] 2019 Jul 08; Vol. 36 (1), pp. 100-114.e25. Date of Electronic Publication: 2019 Jun 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Enzyme Inhibitors/*pharmacology , Protein-Arginine N-Methyltransferases/*antagonists & inhibitors , Purine-Nucleoside Phosphorylase/*deficiency, Alternative Splicing ; Antineoplastic Agents/chemistry ; Biomarkers ; Cell Line, Tumor ; Drug Synergism ; Enzyme Inhibitors/chemistry ; Humans ; Methylation ; Models, Molecular ; Molecular Conformation ; Molecular Structure ; Protein Binding ; Protein-Arginine N-Methyltransferases/chemistry ; Substrate Specificity