المؤلفون: Moles MW; Translational Tumorimmunology, Max Delbrück Center, Berlin, Germany., Erdlei H; Translational Tumorimmunology, Max Delbrück Center, Berlin, Germany., Menzel L; Translational Tumorimmunology, Max Delbrück Center, Berlin, Germany., Massaro M; Microenvironmental Regulation in Autoimmunity and Cancer, Max Delbrück Center, Berlin, Germany., Fiori A; Translational Tumorimmunology, Max Delbrück Center, Berlin, Germany., Bunse M; Microenvironmental Regulation in Autoimmunity and Cancer, Max Delbrück Center, Berlin, Germany., Schrimpf M; Translational Tumorimmunology, Max Delbrück Center, Berlin, Germany., Gerlach K; Translational Tumorimmunology, Max Delbrück Center, Berlin, Germany., Gudipati V; Center for Pathophysiology, Infectiology and Immunology, Institute for Hygiene and Applied Immunology, Medical University of Vienna, Vienna, Austria., Reiser J; Fate Therapeutics, San Diego, CA, United States., Mathavan K; Fate Therapeutics, San Diego, CA, United States., Goodrich JP; Fate Therapeutics, San Diego, CA, United States., Huppa JB; Center for Pathophysiology, Infectiology and Immunology, Institute for Hygiene and Applied Immunology, Medical University of Vienna, Vienna, Austria., Krönke J; Department of Hematology, Oncology and Tumorimmunology, Charité-University Medicine Berlin, Berlin, Germany., Valamehr B; Fate Therapeutics, San Diego, CA, United States., Höpken UE; Microenvironmental Regulation in Autoimmunity and Cancer, Max Delbrück Center, Berlin, Germany., Rehm A; Translational Tumorimmunology, Max Delbrück Center, Berlin, Germany.

المصدر: Frontiers in immunology [Front Immunol] 2024 Jun 24; Vol. 15, pp. 1383136. Date of Electronic Publication: 2024 Jun 24 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Multiple Myeloma*/immunology , Multiple Myeloma*/therapy , Receptors, CXCR4*/metabolism , Receptors, CXCR4*/genetics , B-Cell Maturation Antigen*/immunology , B-Cell Maturation Antigen*/metabolism , B-Cell Maturation Antigen*/genetics , Killer Cells, Natural*/immunology , Killer Cells, Natural*/metabolism , Receptors, Chimeric Antigen*/immunology , Receptors, Chimeric Antigen*/genetics , Receptors, Chimeric Antigen*/metabolism , Immunotherapy, Adoptive*/methods , Chemokine CXCL12*/metabolism, Humans ; Cell Line, Tumor ; Cytotoxicity, Immunologic

المؤلفون: Lees J; Paul O'Gorman Leukaemia Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Hay J; Paul O'Gorman Leukaemia Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Moles MW; Paul O'Gorman Leukaemia Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Michie AM; Paul O'Gorman Leukaemia Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.

المصدر: Frontiers in immunology [Front Immunol] 2023 May 18; Vol. 14, pp. 1179101. Date of Electronic Publication: 2023 May 18 (Print Publication: 2023).

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Forkhead Transcription Factors*/genetics , Forkhead Transcription Factors*/metabolism , Neoplasms*/pathology, Humans ; Gene Expression Regulation ; Signal Transduction ; Cell Differentiation

المؤلفون: Wirges A; Translational Tumorimmunology, Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany., Bunse M; Microenvironmental Regulation in Autoimmunity and Cancer, Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany., Joedicke JJ; Translational Tumorimmunology, Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany., Blanc E; Core Unit Bioinformatics, Berlin Institute of Health, 10117 Berlin, Germany., Gudipati V; Medical University of Vienna, Center for Pathophysiology, Infectiology and Immunology, Institute for Hygiene and Applied Immunology, 1090 Vienna, Austria., Moles MW; Translational Tumorimmunology, Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany., Shiku H; Department of Personalized Cancer Immunotherapy, Mie University Graduate School of Medicine, Tsu city, Mie, 514-8507, Japan., Beule D; Core Unit Bioinformatics, Berlin Institute of Health, 10117 Berlin, Germany., Huppa JB; Medical University of Vienna, Center for Pathophysiology, Infectiology and Immunology, Institute for Hygiene and Applied Immunology, 1090 Vienna, Austria., Höpken UE; Microenvironmental Regulation in Autoimmunity and Cancer, Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany., Rehm A; Translational Tumorimmunology, Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany. Electronic address: arehm@mdc-berlin.de.

المصدر: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2022 Nov 02; Vol. 30 (11), pp. 3358-3378. Date of Electronic Publication: 2022 Jul 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Immunotherapy, Adoptive* , Neoplasms*/therapy , Antigens, Neoplasm*/genetics, Animals ; Female ; Humans ; Mice ; MicroRNAs/genetics ; Receptors, Antigen, T-Cell/genetics ; T-Lymphocytes, Cytotoxic ; Gene Silencing ; Immune Checkpoint Proteins

المؤلفون: Hay J; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow., Moles MW; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow., Cassels J; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow., Michie AM; Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow; Alison.Michie@glasgow.ac.uk.

المصدر: Journal of visualized experiments : JoVE [J Vis Exp] 2019 Oct 23 (152). Date of Electronic Publication: 2019 Oct 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media

بيانات الدورية: Publisher: MYJoVE Corporation Country of Publication: United States NLM ID: 101313252 Publication Model: Electronic Cited Medium: Internet ISSN: 1940-087X (Electronic) Linking ISSN: 1940087X NLM ISO Abbreviation: J Vis Exp Subsets: MEDLINE

مواضيع طبية MeSH: Cell Fractionation/*methods , Leukemia, Lymphocytic, Chronic, B-Cell/*metabolism , Protein Transport/*physiology, Active Transport, Cell Nucleus ; Carrier Proteins/metabolism ; Cell Nucleus/metabolism ; Cytoplasm/metabolism ; Cytosol/metabolism ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/pathology ; Nuclear Proteins/metabolism ; Signal Transduction

المؤلفون: Cosimo E; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Tarafdar A; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Moles MW; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Holroyd AK; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Malik N; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Catherwood MA; Department of Haematology, Belfast City Hospital, Belfast, United Kingdom., Hay J; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Dunn KM; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Macdonald AM; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom., Guichard SM; Forma Therapeutics, Watertown, Massachusetts., O'Rourke D; Department of Histopathology, Belfast City Hospital, Belfast, United Kingdom., Leach MT; Department of Haematology, Gartnavel General Hospital, Glasgow, United Kingdom., Sansom OJ; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.; Cancer Research UK Beatson Institute, Garscube Estate, Glasgow, United Kingdom., Cosulich SC; Bioscience, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, United Kingdom., McCaig AM; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.; Royal Alexandra Hospital, Paisley, United Kingdom., Michie AM; Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom. Alison.Michie@glasgow.ac.uk.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2019 Mar 01; Vol. 25 (5), pp. 1574-1587. Date of Electronic Publication: 2018 Dec 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Forkhead Box Protein O1/*metabolism , Leukemia, Lymphocytic, Chronic, B-Cell/*metabolism , Leukemia, Lymphocytic, Chronic, B-Cell/*mortality , Mechanistic Target of Rapamycin Complex 2/*antagonists & inhibitors , Protein Kinase Inhibitors/*pharmacology , Proto-Oncogene Proteins c-akt/*antagonists & inhibitors , Receptors, Antigen, B-Cell/*metabolism, Animals ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Disease Models, Animal ; Drug Synergism ; Female ; Forkhead Box Protein O1/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy ; Leukemia, Lymphocytic, Chronic, B-Cell/genetics ; Male ; Mechanistic Target of Rapamycin Complex 2/metabolism ; Mice ; Mice, Transgenic ; Prognosis ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/drug effects ; Treatment Outcome ; Xenograft Model Antitumor Assays

المؤلفون: Mourabit S; Biosciences, College of Life & Environmental Sciences, University of Exeter, Exeter, United Kingdom., Moles MW; Biosciences, College of Life & Environmental Sciences, University of Exeter, Exeter, United Kingdom., Smith E; Biosciences, College of Life & Environmental Sciences, University of Exeter, Exeter, United Kingdom., van Aerle R; Biosciences, College of Life & Environmental Sciences, University of Exeter, Exeter, United Kingdom., Kudoh T; Biosciences, College of Life & Environmental Sciences, University of Exeter, Exeter, United Kingdom.

المصدر: PloS one [PLoS One] 2014 Jan 30; Vol. 9 (1), pp. e84786. Date of Electronic Publication: 2014 Jan 30 (Print Publication: 2014).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Bone Morphogenetic Proteins/*physiology , Fish Proteins/*physiology , Killifishes/*embryology, Animals ; Body Patterning/genetics ; Bone Morphogenetic Proteins/antagonists & inhibitors ; Embryo, Nonmammalian/metabolism ; Fish Proteins/antagonists & inhibitors ; Killifishes/metabolism ; Neural Tube/embryology ; Phenotype ; Pyrazoles/pharmacology ; Pyrimidines/pharmacology ; Somites/embryology