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1
المؤلفون: Montse Erra, Jordi Gràcia, Joan Taltavull, Lluís Pagès, Elena Calama, María Domínguez, J.F. Caturla, Sonia Espinosa, F.J. Bernal, M. Carrascal, Mónica Bravo, M. I. Maldonado, Begoña Hernández, M Sabate, Montserrat Miralpeix, Marta Calbet, Stephane Paris, Lehner, M. Mir
المصدر: Journal of Medicinal Chemistry. 61:9551-9567
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Drug, Class I Phosphatidylinositol 3-Kinases, Protein Conformation, media_common.quotation_subject, Perforation (oil well), Pharmacology, 01 natural sciences, Inhibitory Concentration 50, Pulmonary Disease, Chronic Obstructive, 03 medical and health sciences, chemistry.chemical_compound, Therapeutic index, Administration, Inhalation, Drug Discovery, medicine, Humans, Enzyme Inhibitors, Pneumonitis, media_common, COPD, Dose-Response Relationship, Drug, Inhalation, 010405 organic chemistry, Chemistry, medicine.disease, Duvelisib, Asthma, 0104 chemical sciences, 030104 developmental biology, Molecular Medicine, Idelalisib
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2
المؤلفون: Montserrat Miralpeix, Montse Erra, Stephane Paris, Elena Calama, Francisco Javier Bernal, Jordi Gràcia, Martin D. Lehner, María Domínguez, Joan Taltavull, Salome Soria, Mónica Bravo, Clara Armengol, Begoña Hernández, Juan Francisco Caturla, Judit Cabedo, M Sabate, Angelique Gréco
المصدر: ACS Medicinal Chemistry Letters. 8:118-123
مصطلحات موضوعية: 0301 basic medicine, Organic Chemistry, Dosing regimen, Pharmacology, Biology, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Pharmacokinetics, chemistry, Drug Discovery, Structure–activity relationship, Specific immune cell, Phosphatidylinositol
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3
المؤلفون: Montserrat Miralpeix, Manel López, Marcos Castillo, Montse Erra, Adelina Orellana, Bernat Vidal, Marta Mir, Pilar Forns, Isabel Ramis, M. I. Maldonado, Cristina Carreño
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:5419-5423
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Aminopyridines, Pharmaceutical Science, Syk, Biochemistry, Cell Degranulation, Cell Line, Drug Discovery, medicine, Humans, Syk Kinase, Mast Cells, Protein Kinase Inhibitors, Molecular Biology, IC50, Syk kinase, Binding Sites, Chemistry, Organic Chemistry, Intracellular Signaling Peptides and Proteins, Degranulation, Rational design, Protein-Tyrosine Kinases, Mast cell, Molecular Docking Simulation, medicine.anatomical_structure, Molecular Medicine
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4
المؤلفون: Jordi Sanahuja, Montse Erra, Nuria Godessart, Raquel F. Reinoso, Estrella Lozoya, Imma Moreno, Pilar Pizcueta, Julio C. Castro-Palomino, Miriam Andrés
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:7268-7272
مصطلحات موضوعية: Oxidoreductases Acting on CH-CH Group Donors, Toluidines, Stereochemistry, Clinical Biochemistry, Dihydroorotate Dehydrogenase, Hydroxybutyrates, Pharmaceutical Science, Biochemistry, Peripheral blood mononuclear cell, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Nitriles, Drug Discovery, Teriflunomide, Animals, Humans, Computer Simulation, Enzyme Inhibitors, Molecular Biology, Binding Sites, Chemistry, Biphenyl Compounds, Organic Chemistry, Arthritis, Experimental, Protein Structure, Tertiary, Rats, Crotonates, Drug Design, Dihydroorotate dehydrogenase, Molecular Medicine