المؤلفون: Polloni AE; Department of Chemical and Food Engineering, Federal University of Santa Catarina (UFSC), P.O. Box 476, Florianopolis, SC, 88040-900, Brazil., Chiaradia V; Department of Chemical and Food Engineering, Federal University of Santa Catarina (UFSC), P.O. Box 476, Florianopolis, SC, 88040-900, Brazil., Figura EM; Department of Chemical and Food Engineering, Federal University of Santa Catarina (UFSC), P.O. Box 476, Florianopolis, SC, 88040-900, Brazil., De Paoli JP; Department of Chemical and Food Engineering, Federal University of Santa Catarina (UFSC), P.O. Box 476, Florianopolis, SC, 88040-900, Brazil., de Oliveira D; Department of Chemical and Food Engineering, Federal University of Santa Catarina (UFSC), P.O. Box 476, Florianopolis, SC, 88040-900, Brazil., de Oliveira JV; Department of Chemical and Food Engineering, Federal University of Santa Catarina (UFSC), P.O. Box 476, Florianopolis, SC, 88040-900, Brazil., de Araujo PHH; Department of Chemical and Food Engineering, Federal University of Santa Catarina (UFSC), P.O. Box 476, Florianopolis, SC, 88040-900, Brazil., Sayer C; Department of Chemical and Food Engineering, Federal University of Santa Catarina (UFSC), P.O. Box 476, Florianopolis, SC, 88040-900, Brazil. claudia.sayer@ufsc.br.

المصدر: Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2018 Feb; Vol. 184 (2), pp. 659-672. Date of Electronic Publication: 2017 Aug 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 8208561 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0291 (Electronic) Linking ISSN: 02732289 NLM ISO Abbreviation: Appl Biochem Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Polyesters*/chemical synthesis , Polyesters*/chemistry, Enzymes, Immobilized/*chemistry , Fungal Proteins/*chemistry , Lipase/*chemistry, Catalysis

المؤلفون: Choi JH; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Wang KW; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Zhang D; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Zhan X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390.; Quantitative Biomedical Research Center, Department of Clinical Science, University of Texas Southwestern Medical Center, Dallas, TX 75390., Wang T; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390.; Quantitative Biomedical Research Center, Department of Clinical Science, University of Texas Southwestern Medical Center, Dallas, TX 75390., Bu CH; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Behrendt CL; Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX 75390.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390., Zeng M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Wang Y; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Misawa T; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Li X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Tang M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Zhan X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Scott L; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Hildebrand S; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Murray AR; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Moresco EM; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Hooper LV; Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX 75390.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390., Beutler B; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390; Bruce.Beutler@UTSouthwestern.edu.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Feb 14; Vol. 114 (7), pp. E1196-E1204. Date of Electronic Publication: 2017 Jan 30.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Immunoglobulin Class Switching*, Immunoglobulin D/*immunology , Lymphoid Tissue/*immunology , Microbiota/*immunology , Mucous Membrane/*immunology, Animals ; Cytidine Deaminase/genetics ; Cytidine Deaminase/immunology ; Cytidine Deaminase/metabolism ; DNA End-Joining Repair ; Female ; Immunoglobulin D/genetics ; Immunoglobulin D/metabolism ; Lymphoid Tissue/metabolism ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Microbiota/genetics ; Mucous Membrane/metabolism ; Myeloid Differentiation Factor 88/genetics ; Myeloid Differentiation Factor 88/immunology ; Myeloid Differentiation Factor 88/metabolism ; Recombination, Genetic ; Tumor Suppressor p53-Binding Protein 1/deficiency ; Tumor Suppressor p53-Binding Protein 1/genetics ; Tumor Suppressor p53-Binding Protein 1/immunology

المؤلفون: Zhang Z; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Turer E; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Li X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Zhan X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Choi M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Tang M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Press A; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Smith SR; Translational Research institute for Metabolism and Diabetes, Florida Hospital, Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827; Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827., Divoux A; Translational Research institute for Metabolism and Diabetes, Florida Hospital, Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827; Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827., Moresco EM; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390., Beutler B; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390; Bruce.Beutler@UTSouthwestern.edu.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 Oct 18; Vol. 113 (42), pp. E6418-E6426. Date of Electronic Publication: 2016 Oct 05.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease* , Insulin Resistance*/genetics, Diabetes Mellitus/*etiology , Diabetes Mellitus/*metabolism , Diet/*adverse effects, Adipocytes/metabolism ; Adipose Tissue/metabolism ; Adipose Tissue/transplantation ; Animals ; Blood Glucose ; Class Ia Phosphatidylinositol 3-Kinase/genetics ; Class Ia Phosphatidylinositol 3-Kinase/metabolism ; Cullin Proteins/metabolism ; Disease Models, Animal ; Fatty Liver/etiology ; Fatty Liver/metabolism ; Fatty Liver/pathology ; Gene Expression Regulation ; Genetic Association Studies ; Genotype ; Insulin/blood ; Lipodystrophy/etiology ; Lipodystrophy/metabolism ; Lipodystrophy/pathology ; Male ; Mice ; Mice, Knockout ; Mice, Transgenic ; Mutation ; Obesity/etiology ; Obesity/pathology ; Phenotype ; Protein Binding ; Protein Transport ; Signal Transduction ; Ubiquitination

المؤلفون: Shi H; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Wang Y; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Li X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Zhan X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Tang M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Fina M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Su L; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Pratt D; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Bu CH; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Hildebrand S; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Lyon S; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Scott L; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Quan J; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Sun Q; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Russell J; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Arnett S; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Jurek P; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Chen D; Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Kravchenko VV; Department of Immunology and Microbial Sciences, The Scripps Research Institute, La Jolla, California, USA., Mathison JC; Department of Immunology and Microbial Sciences, The Scripps Research Institute, La Jolla, California, USA., Moresco EM; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Monson NL; Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Ulevitch RJ; Department of Immunology and Microbial Sciences, The Scripps Research Institute, La Jolla, California, USA., Beutler B; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

المصدر: Nature immunology [Nat Immunol] 2016 Mar; Vol. 17 (3), pp. 250-8. Date of Electronic Publication: 2015 Dec 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Carrier Proteins/*immunology , Macrophages/*immunology , Mitosis/*immunology , Protein Serine-Threonine Kinases/*immunology, Animals ; Apoptosis ; Apoptosis Regulatory Proteins ; CARD Signaling Adaptor Proteins ; Carrier Proteins/genetics ; Caspase 1 ; Chromatography, Gel ; Colony-Forming Units Assay ; Cytokines ; Cytoskeletal Proteins ; Dendritic Cells ; Encephalomyelitis, Autoimmune, Experimental/immunology ; Female ; Flow Cytometry ; HEK293 Cells ; Humans ; Immunoprecipitation ; In Vitro Techniques ; Inflammasomes/genetics ; Inflammasomes/immunology ; Macrophages, Peritoneal/immunology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/metabolism ; Monocytes ; NIMA-Related Kinases ; NLR Family, Pyrin Domain-Containing 3 Protein ; Protein Serine-Threonine Kinases/genetics ; Reactive Oxygen Species ; Spinal Cord/immunology

المؤلفون: Wang Y; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Su L; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Morin MD; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037;, Jones BT; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037;, Whitby LR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037;, Surakattula MM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037;, Huang H; Department of Genetics, The Scripps Research Institute, La Jolla, CA 92037., Shi H; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Choi JH; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Wang KW; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Moresco EM; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Berger M; Department of Genetics, The Scripps Research Institute, La Jolla, CA 92037., Zhan X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Zhang H; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390; Bruce.Beutler@UTSouthwestern.edu boger@scripps.edu zhang@chop.swmed.edu., Boger DL; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037; Bruce.Beutler@UTSouthwestern.edu boger@scripps.edu zhang@chop.swmed.edu., Beutler B; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390; Bruce.Beutler@UTSouthwestern.edu boger@scripps.edu zhang@chop.swmed.edu.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 Feb 16; Vol. 113 (7), pp. E884-93. Date of Electronic Publication: 2016 Feb 01.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Lipopolysaccharides/*pharmacology , Lymphocyte Antigen 96/*agonists , Peptidomimetics/*pharmacology , Toll-Like Receptor 4/*agonists, Animals ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Mitogen-Activated Protein Kinases/metabolism ; NF-kappa B/metabolism ; Protein Serine-Threonine Kinases/metabolism ; Signal Transduction

المؤلفون: Simon MM; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell Campus, Oxfordshire, OX11 0RD, UK. m.simon@har.mrc.ac.uk., Moresco EM; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Bull KR; Nuffield Department of Medicine and Wellcome Trust Centre for Human Genetics, Oxford University, Oxford, UK.; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, Oxford, UK., Kumar S; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell Campus, Oxfordshire, OX11 0RD, UK., Mallon AM; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell Campus, Oxfordshire, OX11 0RD, UK., Beutler B; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Potter PK; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell Campus, Oxfordshire, OX11 0RD, UK.

المصدر: Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2015 Oct; Vol. 26 (9-10), pp. 486-500. Date of Electronic Publication: 2015 Oct 08.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Springer-Verlag Country of Publication: United States NLM ID: 9100916 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1777 (Electronic) Linking ISSN: 09388990 NLM ISO Abbreviation: Mamm Genome Subsets: MEDLINE

مواضيع طبية MeSH: High-Throughput Nucleotide Sequencing*, Genome/*drug effects , Mutation/*drug effects, Animals ; Disease Models, Animal ; Ethylnitrosourea/toxicity ; Mice ; Mutagenesis/drug effects ; Mutagenesis/genetics ; Mutation/genetics

المؤلفون: Wang T; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390; Quantitative Biomedical Research Center, Department of Clinical Science, University of Texas Southwestern Medical Center, Dallas, TX 75390; and., Zhan X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390; Quantitative Biomedical Research Center, Department of Clinical Science, University of Texas Southwestern Medical Center, Dallas, TX 75390; and., Bu CH; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Lyon S; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Pratt D; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Hildebrand S; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Choi JH; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Zhang Z; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Zeng M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Wang KW; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Turer E; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Chen Z; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Zhang D; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Yue T; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Wang Y; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Shi H; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Wang J; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Sun L; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, SoRelle J; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, McAlpine W; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Hutchins N; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Zhan X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Fina M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Gobert R; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Quan J; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Kreutzer M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Arnett S; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Hawkins K; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Leach A; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Tate C; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Daniel C; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Reyna C; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Prince L; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Davis S; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Purrington J; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Bearden R; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Weatherly J; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, White D; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Russell J; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Sun Q; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Tang M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Li X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Scott L; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, Moresco EM; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390;, McInerney GM; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, SE-171, 77 Stockholm, Sweden., Karlsson Hedestam GB; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, SE-171, 77 Stockholm, Sweden., Xie Y; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390; Quantitative Biomedical Research Center, Department of Clinical Science, University of Texas Southwestern Medical Center, Dallas, TX 75390; and., Beutler B; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390; Bruce.Beutler@UTSouthwestern.edu.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2015 Feb 03; Vol. 112 (5), pp. E440-9. Date of Electronic Publication: 2015 Jan 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Point Mutation*, Alleles ; Animals ; Female ; Genes, Lethal ; Genetic Linkage ; Male ; Mice ; Pedigree ; Phenotype ; Quantitative Trait Loci

المؤلفون: Zeng M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA., Hu Z; Department of Pediatrics and Children's Medical Center Research Institute, and McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA., Shi X; Department of Pediatrics and Children's Medical Center Research Institute, and McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA., Li X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA., Zhan X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA., Li XD; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA. Howard Hughes Medical Institute, Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9148, USA., Wang J; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA. Howard Hughes Medical Institute, Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9148, USA., Choi JH; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA., Wang KW; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA., Purrington T; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA., Tang M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA., Fina M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA., DeBerardinis RJ; Department of Pediatrics and Children's Medical Center Research Institute, and McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA., Moresco EM; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA., Pedersen G; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Nobels väg 16, SE-171 77 Stockholm, Sweden., McInerney GM; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Nobels väg 16, SE-171 77 Stockholm, Sweden., Karlsson Hedestam GB; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Nobels väg 16, SE-171 77 Stockholm, Sweden., Chen ZJ; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA. Howard Hughes Medical Institute, Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9148, USA., Beutler B; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8502, USA. Bruce.Beutler@UTSouthwestern.edu.

المصدر: Science (New York, N.Y.) [Science] 2014 Dec 19; Vol. 346 (6216), pp. 1486-92.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Retracted Publication

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Adaptor Proteins, Signal Transducing/*immunology , Antigens, T-Independent/*immunology , B-Lymphocytes/*immunology , Endogenous Retroviruses/*immunology , Nucleotidyltransferases/*immunology , RNA, Viral/*immunology, Adaptor Proteins, Signal Transducing/genetics ; Animals ; Antibody Formation ; Cytosol/immunology ; DNA/immunology ; Endogenous Retroviruses/genetics ; Lymphocyte Activation ; Membrane Proteins/immunology ; Mice ; Mice, Inbred C57BL ; NF-kappa B/metabolism ; Nucleotides, Cyclic/immunology ; Nucleotidyltransferases/genetics ; RNA, Viral/genetics ; Transcription, Genetic

المؤلفون: Chen Z; Center for Genetics of Host Defense., Holland W; Department of Internal Medicine, Touchstone Diabetes Center., Shelton JM; Department of Internal Medicine, Division of Cardiology., Ali A; Department of Internal Medicine, and., Zhan X; Center for Genetics of Host Defense., Won S; Center for Genetics of Host Defense., Tomisato W; Center for Genetics of Host Defense., Liu C; Department of Internal Medicine, Division of Hypothalamic Research, University of Texas Southwestern Medical Center, Dallas, TX 75390., Li X; Center for Genetics of Host Defense., Moresco EM; Center for Genetics of Host Defense., Beutler B; Center for Genetics of Host Defense, bruce.beutler@utsouthwestern.edu.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 May 20; Vol. 111 (20), pp. 7367-72. Date of Electronic Publication: 2014 May 05.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Mutation* , Signal Transduction*, Multiprotein Complexes/*metabolism , Repressor Proteins/*genetics , TOR Serine-Threonine Kinases/*metabolism, 14-3-3 Proteins/metabolism ; Adipocytes/cytology ; Amino Acid Motifs ; Animals ; Body Composition ; Female ; Glucose/metabolism ; Glucose Tolerance Test ; Male ; Mechanistic Target of Rapamycin Complex 1 ; Mice ; Mice, Inbred C57BL ; Mutagenesis ; Phenotype ; Phosphorylation ; RNA-Binding Proteins/metabolism ; Repressor Proteins/physiology

المؤلفون: Moresco EM; Center for Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75235-8505, USA., Li X, Beutler B

المصدر: The American journal of pathology [Am J Pathol] 2013 May; Vol. 182 (5), pp. 1462-73.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0370502 Publication Model: Print Cited Medium: Internet ISSN: 1525-2191 (Electronic) Linking ISSN: 00029440 NLM ISO Abbreviation: Am J Pathol Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Techniques/*trends, Animals ; Genetic Testing ; Genome/genetics ; High-Throughput Nucleotide Sequencing ; Humans ; Mice ; Mutagenesis/genetics ; Mutation/genetics