المؤلفون: Mosa FES; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada., Alqahtani MA; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada., El-Ghiaty MA; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada., El-Mahrouk SR; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada., Barakat K; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada., El-Kadi AOS; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada. Electronic address: aelkadi@ualberta.ca.

المصدر: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2024 Sep; Vol. 759, pp. 110088. Date of Electronic Publication: 2024 Jul 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0384 (Electronic) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE

مواضيع طبية MeSH: Imidazoles*/pharmacology , Imidazoles*/chemistry , Piperidines*/pharmacology , Piperidines*/chemistry , Pyridazines*/pharmacology , Pyridazines*/chemistry , Pyrimidines*/pharmacology , Pyrimidines*/chemistry , Receptors, Aryl Hydrocarbon*/metabolism , Receptors, Aryl Hydrocarbon*/agonists , Receptors, Aryl Hydrocarbon*/chemistry , Receptors, Aryl Hydrocarbon*/antagonists & inhibitors , Tyrosine Kinase Inhibitors*/chemistry , Tyrosine Kinase Inhibitors*/pharmacology, Humans ; Binding Sites ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 CYP1A1/antagonists & inhibitors ; Ligands ; Molecular Docking Simulation ; Protein Binding

المؤلفون: AlRawashdeh S; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada., Mosa FES; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada., Barakat KH; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.

المصدر: Frontiers in molecular biosciences [Front Mol Biosci] 2024 Aug 13; Vol. 11, pp. 1341727. Date of Electronic Publication: 2024 Aug 13 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101653173 Publication Model: eCollection Cited Medium: Print ISSN: 2296-889X (Print) Linking ISSN: 2296889X NLM ISO Abbreviation: Front Mol Biosci Subsets: PubMed not MEDLINE

المؤلفون: Mosa FES; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada., Alqahtani MA; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada., El-Ghiaty MA; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada., Dyck JRB; Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada., Barakat K; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada., El-Kadi AOS; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada.

المصدر: Drug development research [Drug Dev Res] 2024 Aug; Vol. 85 (5), pp. e22232.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print Cited Medium: Internet ISSN: 1098-2299 (Electronic) Linking ISSN: 02724391 NLM ISO Abbreviation: Drug Dev Res Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Aryl Hydrocarbon*/metabolism , Receptors, Aryl Hydrocarbon*/antagonists & inhibitors , Receptors, Aryl Hydrocarbon*/chemistry , Allosteric Site*, Humans ; Allosteric Regulation/drug effects ; Pyrimidines/pharmacology ; Pyrimidines/chemistry ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Basic Helix-Loop-Helix Transcription Factors/antagonists & inhibitors ; Basic Helix-Loop-Helix Transcription Factors/chemistry ; Molecular Dynamics Simulation ; Drug Approval ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 CYP1A1/antagonists & inhibitors

المؤلفون: Hidayat R; Faculty of Pharmacy & Pharmaceutical Sciences, 2142J Katz Group-Rexall Centre for Pharmacy and Health Research, University of Alberta, Edmonton, AL, T6G 2E1, Canada., Shoieb SM; Faculty of Pharmacy & Pharmaceutical Sciences, 2142J Katz Group-Rexall Centre for Pharmacy and Health Research, University of Alberta, Edmonton, AL, T6G 2E1, Canada., Mosa FES; Faculty of Pharmacy & Pharmaceutical Sciences, 2142J Katz Group-Rexall Centre for Pharmacy and Health Research, University of Alberta, Edmonton, AL, T6G 2E1, Canada., Barakat K; Faculty of Pharmacy & Pharmaceutical Sciences, 2142J Katz Group-Rexall Centre for Pharmacy and Health Research, University of Alberta, Edmonton, AL, T6G 2E1, Canada., Brocks DR; Faculty of Pharmacy & Pharmaceutical Sciences, 2142J Katz Group-Rexall Centre for Pharmacy and Health Research, University of Alberta, Edmonton, AL, T6G 2E1, Canada., Isse FA; Faculty of Pharmacy & Pharmaceutical Sciences, 2142J Katz Group-Rexall Centre for Pharmacy and Health Research, University of Alberta, Edmonton, AL, T6G 2E1, Canada., Gerges SH; Faculty of Pharmacy & Pharmaceutical Sciences, 2142J Katz Group-Rexall Centre for Pharmacy and Health Research, University of Alberta, Edmonton, AL, T6G 2E1, Canada., El-Kadi AOS; Faculty of Pharmacy & Pharmaceutical Sciences, 2142J Katz Group-Rexall Centre for Pharmacy and Health Research, University of Alberta, Edmonton, AL, T6G 2E1, Canada. aelkadi@ualberta.ca.

المصدر: Molecular and cellular biochemistry [Mol Cell Biochem] 2024 Jun; Vol. 479 (6), pp. 1379-1390. Date of Electronic Publication: 2023 Jul 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol Cell Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Cytochrome P-450 CYP1B1*/metabolism , Cytochrome P-450 CYP1B1*/genetics , Hydroxyeicosatetraenoic Acids*/metabolism , Hydroxyeicosatetraenoic Acids*/pharmacology, Humans ; Allosteric Regulation/drug effects

المؤلفون: Tran NH; Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada., Mosa FES; Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada., Barakat K; Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada., El-Kadi AOS; Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada., Whittal R; Department of Chemistry, Faculty of Sciences, College of Natural and Applied Sciences, University of Alberta, Edmonton, Alberta, Canada., Siraki AG; Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada. Electronic address: siraki@ualberta.ca.

المصدر: Chemico-biological interactions [Chem Biol Interact] 2024 Apr 01; Vol. 392, pp. 110942. Date of Electronic Publication: 2024 Mar 07.

نوع المنشور: Comparative Study; Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE

مواضيع طبية MeSH: Neutrophils*/metabolism , Xenobiotics*/metabolism, Humans ; Cytochrome P-450 Enzyme System/metabolism ; Heme/metabolism ; Molecular Docking Simulation ; Oxidative Stress ; Peroxidase/metabolism

المؤلفون: Mosa FES; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada., Alqahtani MA; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada., El-Ghiaty MA; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada., Barakat K; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada. Electronic address: kbarakat@ualberta.ca., El-Kadi AOS; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada. Electronic address: aelkadi@ualberta.ca.

المصدر: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2024 Apr; Vol. 754, pp. 109958. Date of Electronic Publication: 2024 Mar 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0384 (Electronic) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Aryl Hydrocarbon*/metabolism, Binding Sites ; Protein Binding ; Protein Domains ; Ligands

المؤلفون: Mosa FES; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB T6G 2E1, Canada., AlRawashdeh S; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB T6G 2E1, Canada., El-Kadi AOS; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB T6G 2E1, Canada., Barakat K; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB T6G 2E1, Canada.

المصدر: Journal of chemical information and modeling [J Chem Inf Model] 2024 Mar 25; Vol. 64 (6), pp. 2021-2034. Date of Electronic Publication: 2024 Mar 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Aryl Hydrocarbon*/metabolism , Artificial Intelligence*, Humans ; Ligands ; Aryl Hydrocarbon Receptor Nuclear Translocator/chemistry ; Aryl Hydrocarbon Receptor Nuclear Translocator/genetics ; Aryl Hydrocarbon Receptor Nuclear Translocator/metabolism

المؤلفون: Mosa FES; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada., El-Kadi AOS; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada., Barakat K; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada. Electronic address: kbarakat@ualberta.ca.

المصدر: Journal of molecular graphics & modelling [J Mol Graph Model] 2023 Jan; Vol. 118, pp. 108339. Date of Electronic Publication: 2022 Sep 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science, Inc Country of Publication: United States NLM ID: 9716237 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4243 (Electronic) Linking ISSN: 10933263 NLM ISO Abbreviation: J Mol Graph Model Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Aryl Hydrocarbon*/metabolism , Gene Expression Regulation*, Humans ; Mice ; Animals ; Ligands ; Protein Binding

المؤلفون: Abookleesh F; Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB T6G 2P5, Canada., Mosa FES; Faculty of Pharmacy & Pharmaceutical Sciences, University of Alberta, Edmonton, AB T6G 2H5, Canada., Barakat K; Faculty of Pharmacy & Pharmaceutical Sciences, University of Alberta, Edmonton, AB T6G 2H5, Canada., Ullah A; Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB T6G 2P5, Canada.

المصدر: Polymers [Polymers (Basel)] 2022 Sep 05; Vol. 14 (17). Date of Electronic Publication: 2022 Sep 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101545357 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4360 (Electronic) Linking ISSN: 20734360 NLM ISO Abbreviation: Polymers (Basel) Subsets: PubMed not MEDLINE

المؤلفون: Mosa FES; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Ab, Canada., C S; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Ab, Canada., Feng T; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Ab, Canada., Barakat K; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Ab, Canada; Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Alberta, Canada. Electronic address: kbarakat@ualberta.ca.

المصدر: Journal of molecular graphics & modelling [J Mol Graph Model] 2021 Jan; Vol. 102, pp. 107776. Date of Electronic Publication: 2020 Oct 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science, Inc Country of Publication: United States NLM ID: 9716237 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4243 (Electronic) Linking ISSN: 10933263 NLM ISO Abbreviation: J Mol Graph Model Subsets: MEDLINE

مواضيع طبية MeSH: Calcium Channel Blockers*/pharmacology , Calcium Channels, L-Type*/metabolism, Binding Sites ; Calcium ; Humans ; Ion Channels ; Ions