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المؤلفون: Shuoker, Bashar, Pichler, Michael J., Jin, Chunsheng, Sakanaka, Hiroka, Wu, Haiyang, Gascueña, Ana Martínez, Liu, Jining, Nielsen, Tine Sofie, Holgersson, Jan, Nordberg Karlsson, Eva, Juge, Nathalie, Meier, Sebastian, Morth, Jens Preben, Karlsson, Niclas G., Abou Hachem, Maher
المصدر: Nature Communications. 14
مصطلحات موضوعية: Humans, Mucins/metabolism, Neuraminidase/metabolism, alpha-L-Fucosidase/metabolism, N-Acetylneuraminic Acid/metabolism, Fucose/metabolism, Verrucomicrobia/metabolism, Polysaccharides/metabolism, Mucus/metabolism, Naturvetenskap, Biologi, Immunologi, Natural Sciences, Biological Sciences, Immunology, Mikrobiologi, Microbiology
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المصدر: Journal of experimental medicine. 220(1)
مصطلحات موضوعية: Mice, Ulcerative/metabolism, Verrucomicrobia/metabolism, Lectins, Animals, Humans, Mucus/metabolism, Colitis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___00893::41793e4819663c662a74d770dda84cdf
https://doi.org/10.1084/jem.20211938 -
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المؤلفون: Ebbesen, Morten Frendø, Kaspersen, Liselotte, Hansen, Irene M, Thomsen, Troels Kragsig, Bienk, Konrad, Cai, Yunpeng, Malle, Birgitte Mølholm, Howard, Kenneth Alan
المصدر: Ebbesen, M F, Ebbesen, M F, Kaspersen, L, Hansen, I M, Thomsen, T K, Bienk, K, Cai, Y, Malle, B M & Howard, K A 2017, ' Hyaluronic Acid Molecular Weight-Dependent Modulation of Mucin Nanostructure for Potential Mucosal Therapeutic Applications. ', Molecular Pharmaceutics, vol. 14, no. 7, pp. 2359-2367 . https://doi.org/10.1021/acs.molpharmaceut.7b00236
Hansen, I, Ebbesen, M F, Kaspersen, L, Thomsen, T B, Bienk, K, Cai, Y, Malle, B M & Howard, K 2017, ' Hyaluronic Acid Molecular Weight-Dependent Modulation of Mucin Nanostructure for Potential Mucosal Therapeutic Applications ', Molecular Pharmaceutics, vol. 14, no. 7, pp. 2359–2367 . https://doi.org/10.1021/acs.molpharmaceut.7b00236مصطلحات موضوعية: Mucins/chemistry, 0301 basic medicine, Nanostructure, Swine, Pharmaceutical Science, Nanoparticle, Nanoparticle tracking analysis, Mucus/metabolism, 02 engineering and technology, law.invention, 03 medical and health sciences, chemistry.chemical_compound, mucin, mucus, Confocal microscopy, law, hyaluronic acid, Drug Discovery, Hyaluronic acid, Animals, Hyaluronic Acid, Chemistry, Mucin, Mucins, Hydrogels, Hydrogels/chemistry, 021001 nanoscience & nanotechnology, Nanostructures, Molecular Weight, Mucus, 030104 developmental biology, Hyaluronic Acid/chemistry, Biochemistry, drug delivery, Self-healing hydrogels, Drug delivery, Biophysics, Nanoparticles, Molecular Medicine, nanoparticles, Nanoparticles/chemistry, 0210 nano-technology, Nanostructures/chemistry
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المؤلفون: Thierry Pedron, Chek Kun Tan, Kalina Duszka, Robert Ducroc, Philippe J. Sansonetti, Céline Mulet, Rémy Burcelin, Azadeh Saffarian, Béatrice Regnault, Walter Wahli, Jean-Baptiste Cavin, Julie Tomas
المساهمون: MICrobiologie de l'ALImentation au Service de la Santé (MICALIS), Institut National de la Recherche Agronomique (INRA)-AgroParisTech, Pathogénie microbienne moléculaire, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Génotypage des Eucaryotes (Plate-Forme), Institut Pasteur [Paris], Nanyang Technological University [Singapour], Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Fédérale Toulouse Midi-Pyrénées, Center for Integrative Genomics - Institute of Bioinformatics, Génopode (CIG), Swiss Institute of Bioinformatics [Lausanne] (SIB), Université de Lausanne (UNIL)-Université de Lausanne (UNIL), Chaire Microbiologie et Maladies infectieuses, Collège de France (CdF (institution)), This work was supported in part by the Société Française de Nutrition, the Fondation des Treilles created by Anne Gruner Schlumberger (www.les-treilles.com), the French Government’s Investissement d’Avenir program, Laboratoire d’Excellence 'Integrative Biology of Emerging Infectious Diseases' (Grant ANR-10-LABX-62-IBEID), the European Research Council Advanced Grants 339579-DECRYPT (to P.J.S.), a Start-Up Grant from the Lee Kong Chian School of Medicine, Nanyang Technological University, and the 7th EU program TORNADO., We thank Laurence Motreff for her help with the Illumina libraries preparation and the MiSeq run, Eeswari Paramalingam for animal handling and tissue preparation, Jacques Ravel for editing the manuscript, and Nathalie Bechon for her contribution during her fellowship. J.T. was in part funded by the Contrat Jeune Scientifique from the Institut National de la Recherche Agronomique (Jouy-en-Josas, France)., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 339579,EC:FP7:ERC,ERC-2013-ADG,DECRYPT(2014), Centre d'Immunologie de Marseille - Luminy (CIML), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Lausanne = University of Lausanne (UNIL)-Université de Lausanne = University of Lausanne (UNIL), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris] (IP), Collège de France - Chaire Microbiologie et Maladies infectieuses, TOMAS, Julie, PEDRON, Thierry, Integrative Biology of Emerging Infectious Diseases - - IBEID2010 - ANR-10-LABX-0062 - LABX - VALID, Decrypting signals in the crypt. - DECRYPT - - EC:FP7:ERC2014-04-01 - 2019-03-31 - 339579 - VALID, Sansonetti, Philippe J., Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Toulouse (UT), Lee Kong Chian School of Medicine (LKCMedicine)
المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (40), pp.E5934-E5943. ⟨10.1073/pnas.1612559113⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (40), ⟨10.1073/pnas.1612559113⟩
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (40), ⟨10.1073/pnas.1612559113⟩
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (40), pp.E5934-E5943. ⟨10.1073/pnas.1612559113⟩
Proceedings of the National Academy of Sciences of the United States of America 40 (113), E5934-E5943. (2016)مصطلحات موضوعية: Male, 0301 basic medicine, Cystic Fibrosis Transmembrane Conductance Regulator, Peroxisome proliferator-activated receptor, MESH: Cecum/microbiology, Candidatus Arthromitus, MESH: Thiazolidinediones/pharmacology, Feces, antimicrobial peptides, MESH: Chlorides/metabolism, 0302 clinical medicine, Intestine, Small, [SDV.EE.ECO] Life Sciences [q-bio]/Ecology, environment/Ecosystems, MESH: Cystic Fibrosis Transmembrane Conductance Regulator/metabolism, MESH: Diet, High-Fat, MESH: Animals, CFTR, Receptor, Cecum, [SDV.EE]Life Sciences [q-bio]/Ecology, environment, 2. Zero hunger, chemistry.chemical_classification, Multidisciplinary, biology, Microbiota, MESH: Intestine, Small/drug effects, MESH: Laser Capture Microdissection, MESH: Feces/microbiology, MESH: Gastrointestinal Microbiome*/drug effects, MESH: Intestine, Small/physiology, Cystic fibrosis transmembrane conductance regulator, 3. Good health, High-fat diet, Phenotype, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, medicine.anatomical_structure, high-fat diet, PNAS Plus, Biochemistry, Signal Transduction, medicine.medical_specialty, PPAR-γ, MESH: PPAR gamma/genetics, MESH: Rosiglitazone, Ileum, Laser Capture Microdissection, Diet, High-Fat, MESH: Phenotype, Rosiglitazone, 03 medical and health sciences, [SDV.EE.ECO]Life Sciences [q-bio]/Ecology, environment/Ecosystems, Chlorides, MESH: Mice, Inbred C57BL, Internal medicine, medicine, microbiota, Animals, MESH: Antimicrobial Cationic Peptides/metabolism, Intestinal permeability, MESH: Signal Transduction*/drug effects, [SDV.EE.IEO] Life Sciences [q-bio]/Ecology, environment/Symbiosis, medicine.disease, biology.organism_classification, Mucus, MESH: Gene Expression Regulation/drug effects, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, Small intestine, MESH: Male, Gastrointestinal Microbiome, Mice, Inbred C57BL, PPAR gamma, [SDV.AEN] Life Sciences [q-bio]/Food and Nutrition, MESH: PPAR gamma/metabolism, ecosytem, 030104 developmental biology, Endocrinology, Gene Expression Regulation, chemistry, MESH: Antimicrobial Cationic Peptides/genetics, biology.protein, Thiazolidinediones, MESH: Intestine, Small/microbiology, MESH: Mucus/metabolism, [SDV.MP.BAC] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, 030217 neurology & neurosurgery, Antimicrobial Cationic Peptides, [SDV.EE.IEO]Life Sciences [q-bio]/Ecology, environment/Symbiosis
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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d715e572206c92d4584b1dc57bc59c5
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المؤلفون: Jeanna Bugaytsova, Thomas Borén, Joana Gomes, Celso A. Reis, Emmanuel Maes, Anna Shevtsova, Yannick Rossez, Catherine Robbe-Masselot, Ana Magalhães
المساهمون: Instituto de Patologia e Imunologia Molecular da Universidade do Porto (IPATIMUP), Unité de Glycobiologie Structurale et Fonctionnelle UMR 8576 (UGSF), Université de Lille-Centre National de la Recherche Scientifique (CNRS), Umeå University, CNRS, Université de Lille, Unité de Glycobiologie Structurale et Fonctionnelle (UGSF) - UMR 8576, Instituto de Patologia e Imunologia Molecular da Universidade do Porto [IPATIMUP], Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576 [UGSF], Unité de Glycobiologie Structurale et Fonctionnelle UMR 8576 [UGSF], Université de Lille-Institut National de la Recherche Agronomique (INRA)-Centre National de la Recherche Scientifique (CNRS), Instituto de Investigação e Inovação em Saúde
المصدر: Scientific Reports
Scientific Reports, 2016, 6, pp.25575. ⟨10.1038/srep25575⟩
Scientific Reports, Nature Publishing Group, 2016, 6, pp.25575. ⟨10.1038/srep25575⟩
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAPمصطلحات موضوعية: 0301 basic medicine, Glycosylation, Helicobacter pylori/metabolism, Mucus/metabolism, Mucin 5AC, Bacterial Adhesion, chemistry.chemical_compound, 0302 clinical medicine, fluids and secretions, Helicobacter, Fucosylation, Gastric Mucosa/metabolism, Mice, Knockout, Infections/microbiology, Multidisciplinary, Fucosyltransferases/genetics, respiratory system, Fucosyltransferases, 3. Good health, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Helicobacter pylori/physiology, Protein Binding, Biology, Article, Microbiology in the medical area, Microbiology, Helicobacter Infections, Glycocalyx, 03 medical and health sciences, Lewis Blood Group Antigens, Polysaccharides, Mikrobiologi inom det medicinska området, Gastric mucosa, medicine, Animals, Humans, Polysaccharides/metabolism, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Adhesins, Bacterial, Mucin 5AC/metabolism, Cancer och onkologi, Helicobacter pylori, Gastric Mucins, Mucin, biology.organism_classification, Mucus, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, Lewis Blood-Group System/metabolism, Helicobacter Infections/metabolism, Mice, Inbred C57BL, 030104 developmental biology, chemistry, Gastric Mucosa, Cancer and Oncology, Gastric Mucins/metabolism, Fucosyltransferases/metabolism, Adhesins, Bacterial/metabolism
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المؤلفون: Adèle De Arcangelis, Michel Labouesse, Sylvain Normand, Patricia Simon-Assmann, Fabien Alpy, Doulaye Dembélé, Emilie Bruyère, Elisabeth Georges-Labouesse, Stéphanie Siebert, Sophie Rodius, Patrice Laquerriere, Agnès Méchine-Neuville, Patricia Lepage, Mathias Chamaillard, Sylvie Robine, Isabelle Van Seuningen, Véronique Pfister, Hussein Hamade, Michèle Kedinger, Olivier Lefebvre, Anne Delanoye-Crespin
المساهمون: Forces mécaniques et morphogénèse des tissus = Mechanical forces behind tissue morphogenesis (LBD-E08), Laboratoire de Biologie du Développement (LBD), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), CNRS, Inserm, Universite de Strasbourg, Association pour la Recherche sur le Cancer and Ligue Regionale contre le Cancer (EG-L), Fondation pour la Recherche Medicale ('Equipe FRM'), Institut National du Cancer (Appel a projets 'Formes precoces du cancer colorectal'), Agence Nationale pour la Recherche, LabEx INRT (IGBMC, UdS), Ligue contre le Cancer, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), De Arcangelis, Adèle, Labouesse, Michel
المصدر: Gut
Gut, 2016, 66 (10), pp.gutjnl--2015--310847. ⟨10.1136/gutjnl-2015-310847⟩
Gut, BMJ Publishing Group, 2016, 66 (10), pp.gutjnl--2015--310847. ⟨10.1136/gutjnl-2015-310847⟩
Gut 10 (66), 1748-1760. (2017)مصطلحات موضوعية: 0301 basic medicine, Basement Membrane/physiopathology, Integrins, Pathology, INTESTINAL BARRIER FUNCTION, T-Lymphocytes, Aucun, Intestinal Mucosa/*metabolism/pathology/physiopathology, Mucus/metabolism, Adaptive Immunity, Integrin alpha6, Intestinal barrier function, Lymphocyte Activation, Severity of Illness Index, Basement Membrane, Caspase 1/metabolism, Mice, Intestinal mucosa, Colorectal Neoplasms/genetics/metabolism/*physiopathology, intestinal inflammation, Homeostasis, genetics, physiology, Myeloid Differentiation Factor 88/genetics, Intestinal Mucosa, [SDV.BDD]Life Sciences [q-bio]/Development Biology, ComputingMilieux_MISCELLANEOUS, COLORECTAL CANCER, B-Lymphocytes, Hemidesmosome, Caspase 1, alpha-6-beta-4 integrin, CELL MATRIX INTERACTION, Gastroenterology, tumor-growth, Hyperplasia, Colitis, Epithelial Cells/metabolism, Cell matrix interaction, 3. Good health, barrier, Adenocarcinoma, Cytokines, medicine.symptom, Colorectal Neoplasms, Signal Transduction, Integrin alpha6/*genetics, medicine.medical_specialty, Ibd, IBD, metabolism, physiopathology, Inflammation, inflammatory-bowel-disease, epidermolysis-bullosa, mice, cells, expression, absence, Biology, Physique [physics]/Physique [physics], digestive system, pathology, Permeability, 03 medical and health sciences, Hemidesmosomes/genetics/*physiology, medicine, Animals, Neoplastic transformation, Adenocarcinoma/genetics/metabolism/*physiopathology, Integrin alpha6beta4, Keratin-18, Keratin-8, Inflammatory Bowel Disease, Epithelial Cells, Hemidesmosomes, Homeostasis/genetics, Keratin-18/metabolism, Keratin-8/metabolism, medicine.disease, Colorectal cancer, INTEGRINS, Mucus, 030104 developmental biology, Colitis/genetics/metabolism/pathology/*physiopathology, Dysplasia, Myeloid Differentiation Factor 88, Integrin alpha6beta4/*metabolism, Cytokines/genetics/*metabolism
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المؤلفون: Dijkstra, Akkelies E., Smolonska, J, Van Den Berge, M, Wijmenga, C, Zanen, P, Luinge, MA, Platteel, M, Lammers, JW, Dahlback, M, Tosh, K, Hiemstra, PS, Sterk, PJ, Spira, A, Vestbo, J, Nordestgaard, BG, Benn, M, Nielsen, SF, Dahl, M, Verschuren, WM, Picavet, HSJ, Smit, HA, Owsijewitsch, M, Kauczor, HU, De Koning, HJ, Nizankowska-Mogilnicka, E, Mejza, F, Nastalek, P, Van Diemen, CC, Cho, MH, Silverman, EK, Crapo, JD, Beaty, TH, Lomas, DA, Bakke, Per, Gulsvik, Amund, Bosse, Y, Obeidat, MA, Loth, DW, Lahousse, L, Rivadeneira, F, Uitterlinden, AG, Hofman, A, Stricker, BH, Brusselle, GG, Van Duijn, CM, Brouwer, U, Koppelman, GH, Vonk, JM, Nawijn, MC, Groen, HJM, Timens, W, Boezen, HM, Postma, DS, Alizadeh, BZ, De Boer, RA, Bruinenberg, M, Franke, L, Van Der Harst, P, Hillege, HL, Van Der Klauw, MM, Navis, G, Ormel, J, Rosmalen, J, Slaets, JP, Snieder, H, Stolk, RP, Wolffenbuttel, B
المساهمون: Amsterdam institute for Infection and Immunity, Pulmonology, Clinical Chemistry, Public Health, Otorhinolaryngology and Head and Neck Surgery, Epidemiology, Internal Medicine, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Life Course Epidemiology (LCE), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS)
المصدر: PLoS ONE
Dijkstra, A E, Smolonska, J, van den Berge, M, Wijmenga, C, Zanen, P, Luinge, M A, Platteel, M, Lammers, J W, Dahlback, M, Tosh, K, Hiemstra, P S, Sterk, P J, Spira, A, Vestbo, J, Nordestgaard, B G, Benn, M, Nielsen, S F, Dahl, M, Verschuren, W M, Picavet, H S J, Smit, H A, Owsijewitsch, M, Kauczor, H U, de Koning, H J, Nizankowska-Mogilnicka, E, Mejza, F, Nastalek, P, van Diemen, C C, Cho, M H, Silverman, E K, Crapo, J D, Beaty, T H, Lomas, D A, Bakke, P, Gulsvik, A, Bosse, Y, Obeidat, M A, Loth, D W, Lahousse, L, Rivadeneira, F, Uitterlinden, A G, Hofman, A, Stricker, B H, Brusselle, G G, van Duijn, C, Brouwer, U, Koppelman, G H, Vonk, J M, Nawijn, M C, Groen, H J M, Timens, W, Boezen, H M, Postma, D S & LifeLines Cohort, S 2014, ' Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study ', P L o S One, vol. 9, no. 4, e91621, pp. 13 . https://doi.org/10.1371/journal.pone.0091621
LifeLines Cohort Study 2014, ' Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study ', PLoS ONE, vol. 9, no. 4, e91621 . https://doi.org/10.1371/journal.pone.0091621
e91621
PLoS ONE, 9(4). Public Library of Science
PLoS One (print), 9(4). Public Library of Science
PLoS ONE, Vol 9, Iss 4, p e91621 (2014)
PLoS ONE, 9(4)
PLOS ONE
PLoS ONE, 9(4):e91621. PUBLIC LIBRARY SCIENCE
PLoS ONE; Vol 9مصطلحات موضوعية: CHROMATIN, Male, Chronic bronchitis, Pulmonology, Epidemiology, OBSTRUCTIVE PULMONARY-DISEASE CHRONIC-BRONCHITIS GENETIC EPIDEMIOLOGY GENERAL-POPULATION BINDING-PROTEIN RISK-FACTORS COPD CHROMATIN SATB1 EXPRESSION, lcsh:Medicine, Genome-wide association study, Lung/metabolism, Mucus/metabolism, Drug Addiction, Matrix Attachment Region Binding Proteins/genetics, Recreational Drug Addiction, Cohort Studies, Pulmonary Disease, Chronic Obstructive, Medicine and Health Sciences, Psychology, Clinical Epidemiology, lcsh:Science, Lung, Cells, Cultured, GENETIC EPIDEMIOLOGY, GENERAL-POPULATION, Aged, 80 and over, education.field_of_study, Multidisciplinary, Medical sciences: 700::Basic medical, dental and veterinary sciences: 710::Medical genetics: 714 [VDP], Genomics, respiratory system, Middle Aged, 3. Good health, Functional Genomics, BINDING-PROTEIN, medicine.anatomical_structure, CHRONIC-BRONCHITIS, Genetic Epidemiology, Medical sciences: 700::Clinical medical sciences: 750::Lung diseases: 777 [VDP], Epidemiological Methods and Statistics, Female, medicine.symptom, Transcriptome Analysis, Medisinske fag: 700::Klinisk medisinske fag: 750::Lungesykdommer: 777 [VDP], Research Article, EXPRESSION, Adult, Chronic Obstructive Pulmonary Disease, Population, Addiction, Single-nucleotide polymorphism, Biology, Environmental and Occupational Lung Diseases, OBSTRUCTIVE PULMONARY-DISEASE, Polymorphism, Single Nucleotide, Environmental Epidemiology, SATB1, SDG 3 - Good Health and Well-being, medicine, Genome-Wide Association Studies, Genetics, SNP, COPD, Humans, education, Lifecourse Epidemiology, Aged, lcsh:R, Biology and Life Sciences, Computational Biology, Correction, Matrix Attachment Region Binding Proteins, Genome Analysis, Pulmonary Disease, Chronic Obstructive/genetics, Medisinske fag: 700::Basale medisinske, odontologiske og veterinærmedisinske fag: 710::Medisinsk genetikk: 714 [VDP], Mucus, Genetic epidemiology, Immunology, Respiratory Infections, Chronic Disease, RISK-FACTORS, Sputum, lcsh:Q, Genome Expression Analysis, Genome-Wide Association Study
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المؤلفون: K E Ludwig, Scheckenbach, Davide, Losa, Tecla, Dudez, Marc, Bacchetta, Scott, O'Grady, Sophie, Crespin, Marc, Chanson
المصدر: American Journal of Respiratory Cell and Molecular Biology, Vol. 44, No 1 (2011) pp. 74-82
مصطلحات موضوعية: Adenosine, Time Factors, Epithelial Cells/drug effects/metabolism, Cell Communication/drug effects, Receptors, Prostaglandin E/metabolism, Cystic Fibrosis Transmembrane Conductance Regulator, Chlorides/metabolism, Cell Communication, Mucus/metabolism, Connexins, Membrane Potentials, Signal Transduction/drug effects, Homeostasis, 5'-Nucleotidase, ddc:618, Microscopy, Confocal, Reverse Transcriptase Polymerase Chain Reaction, Gap Junctions, Cell Polarity, Gap Junctions/drug effects/metabolism, Articles, Cyclooxygenase Inhibitors/pharmacology, Mucociliary Clearance, RNA Interference, 5'-Nucleotidase/metabolism, Signal Transduction, Phospholipase A2 Inhibitors, Surface Properties, Blotting, Western, Respiratory Mucosa, GPI-Linked Proteins, Respiratory Mucosa/drug effects/metabolism, Dinoprostone, Cell Line, GPI-Linked Proteins/metabolism, Mucociliary Clearance/drug effects, Chlorides, Receptors, Purinergic P1/metabolism, Receptors, Prostaglandin E, Humans, Cyclooxygenase Inhibitors, Adenosine/metabolism, Phospholipases A2/antagonists & inhibitors/metabolism, Receptors, Purinergic P1, Cystic Fibrosis Transmembrane Conductance Regulator/genetics/metabolism, Epithelial Cells, Mucus, Phospholipases A2, Dinoprostone/metabolism, Connexins/metabolism
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المؤلفون: Ruiz, Lorena, Gueimonde, Miguel, Couté, Yohann, Salminen, Seppo, Sanchez, Jean-Charles, de los Reyes-Gavilán, Clara G., Margolles, Abelardo
المساهمون: European Commission, Ministerio de Economía y Competitividad (España), Consejo Superior de Investigaciones Científicas (España)
المصدر: FEMS Microbiology Letters, Vol. 314, No 2 (2011) pp. 125-30
Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: Cytoplasm, Bacterial Proteins/analysis, Glycoside Hydrolases, Proteome, Amino Acids/metabolism, Isotopes/metabolism, Glycoproteins/metabolism, Mucus/metabolism, Bifidobacterium/chemistry/growth & development/metabolism, Glycoside Hydrolases/metabolism, fluids and secretions, Bacterial Proteins, Isotopes, Proteome/analysis, Humans, ddc:576, Amino Acids, Glycoproteins, Staining and Labeling, food and beverages, Culture Media, Mucus, Bifidobacterium, Culture Media/chemistry, Staining and Labeling/methods, Cytoplasm/chemistry
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