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1دورية أكاديمية
المصدر: PLoS ONE, Vol 13, Iss 2, p e0192286 (2018)
وصف الملف: electronic resource
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المؤلفون: Mukarram El-Banna, Haiyan Zheng, Amenah Soherwardy, David E. Sleat, Caifeng Zhao, Dirk F. Moore, Jennifer A. Wiseman, Peter Lobel
المصدر: Mol Cell Proteomics
مصطلحات موضوعية: Male, Pathology, medicine.medical_specialty, Proteome, Biology, Biochemistry, Aminopeptidases, Analytical Chemistry, Pathogenesis, 03 medical and health sciences, Mice, Cerebrospinal fluid, Neuronal Ceroid-Lipofuscinoses, Lysosome, medicine, Animals, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Molecular Biology, Neuroinflammation, 030304 developmental biology, chemistry.chemical_classification, Mice, Knockout, 0303 health sciences, Membrane Glycoproteins, Tripeptidyl-Peptidase 1, Research, 030302 biochemistry & molecular biology, Brain, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, medicine.anatomical_structure, chemistry, CLN3, Neuronal ceroid lipofuscinosis, Female, Thiolester Hydrolases, Serine Proteases, Glycoprotein, Lysosomes, Biomarkers, Molecular Chaperones
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253a6fb8bb5beee9c2a0e4f9ba5b46b6
https://pubmed.ncbi.nlm.nih.gov/31501224 -
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المؤلفون: Dana Cruz, David E. Sleat, Amitabha Majumdar, Frederick R. Maxfield, Michelle Muldowney, Mukarram El-Banna, Peter Lobel
مصطلحات موضوعية: Macrophage colony-stimulating factor, chemistry.chemical_classification, 0303 health sciences, Microglia, medicine.disease, Tripeptidyl peptidase, Cell biology, Pathogenesis, 03 medical and health sciences, 0302 clinical medicine, Enzyme, medicine.anatomical_structure, chemistry, medicine, Degradation (geology), Alzheimer's disease, Beta (finance), 030217 neurology & neurosurgery, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86bc0eff1ce7e88e8ba55404f0a738e
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المصدر: PLoS ONE, Vol 13, Iss 2, p e0192286 (2018)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, lcsh:Medicine, Artificial Gene Amplification and Extension, Aminopeptidases, Polymerase Chain Reaction, Biochemistry, Tripeptidyl peptidase, Mice, 0302 clinical medicine, Transgenes, lcsh:Science, Regulation of gene expression, Multidisciplinary, Tripeptidyl-Peptidase 1, Genetically Modified Organisms, Chinese hamster ovary cell, Animal Models, Proteases, Transfection, Enzymes, Cell biology, Experimental Organism Systems, Cell lines, Genetic Engineering, Biological cultures, Research Article, Biotechnology, Genetically modified mouse, Transgene, Mice, Transgenic, Mouse Models, CHO Cells, Biology, Research and Analysis Methods, Gene Expression Regulation, Enzymologic, 03 medical and health sciences, Cricetulus, Model Organisms, Neuronal Ceroid-Lipofuscinoses, Genetics, medicine, Animals, Animal Models of Disease, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Molecular Biology Techniques, Molecular Biology, Alleles, Genetically Modified Animals, lcsh:R, Biology and Life Sciences, Proteins, medicine.disease, Disease Models, Animal, Tamoxifen, 030104 developmental biology, Genetic Loci, Enzymology, Animal Studies, Neuronal ceroid lipofuscinosis, lcsh:Q, Serine Proteases, Homologous recombination, 030217 neurology & neurosurgery
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المؤلفون: Dirk F. Moore, Istvan Sohar, Jennifer A. Wiseman, Haiyan Zheng, Mukarram El-Banna, David E. Sleat, Peter Lobel
المصدر: PROTEOMICS. 12:3499-3509
مصطلحات موضوعية: Proteomics, Vesicular Transport Proteins, Mannose 6-phosphate, Biology, Biochemistry, Article, Mice, chemistry.chemical_compound, Niemann-Pick C1 Protein, Tandem Mass Spectrometry, hemic and lymphatic diseases, Lysosome, medicine, Animals, Molecular Biology, Niemann-Pick Diseases, Prosaposin, Mice, Inbred BALB C, Mannose 6-phosphate receptor, Intracellular Signaling Peptides and Proteins, Brain, Proteins, nutritional and metabolic diseases, medicine.disease, Transmembrane protein, Transport protein, Cell biology, medicine.anatomical_structure, chemistry, lipids (amino acids, peptides, and proteins), NPC1, Transcriptome, Niemann–Pick disease, Gene Deletion
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المؤلفون: David E. Sleat, Lingling Wang, Peter Lobel, Istvan Sohar, Su Xu, Mukarram El-Banna
المصدر: Molecular Therapy. 19(10):1842-1848
مصطلحات موضوعية: Central nervous system, Lysosomal storage disorders, Pharmacology, Biology, Intrathecal, Aminopeptidases, Mice, Cerebrospinal fluid, Neuronal Ceroid-Lipofuscinoses, Drug Discovery, medicine, Clinical endpoint, Genetics, Animals, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Molecular Biology, Injections, Spinal, chemistry.chemical_classification, Tripeptidyl-Peptidase 1, Original Articles, Phenotype, Recombinant Proteins, Disease Models, Animal, Enzyme, medicine.anatomical_structure, chemistry, Immunology, Molecular Medicine, Late infantile neuronal ceroid lipofuscinosis, Serine Proteases
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المؤلفون: Steven U. Walkley, G. Stephen Tint, Sandy Price, Lucie Verot, Peter Lobel, Marie T. Vanier, Mukarram El-Banna, David E. Sleat, Jennifer A. Wiseman, Michael M. Shen
المصدر: Proceedings of the National Academy of Sciences. 101:5886-5891
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Genotype, Blotting, Western, Vesicular Transport Proteins, Biology, medicine.disease_cause, Polymerase Chain Reaction, Mice, Niemann-Pick C1 Protein, hemic and lymphatic diseases, Lysosome, medicine, Animals, Lipid Transport, DNA Primers, Glycoproteins, chemistry.chemical_classification, Mutation, Multidisciplinary, Base Sequence, Cholesterol binding, Intracellular Signaling Peptides and Proteins, Proteins, nutritional and metabolic diseases, Biological Transport, Lipid metabolism, Biological Sciences, Blotting, Northern, Lipid Metabolism, Transmembrane protein, Cell biology, medicine.anatomical_structure, chemistry, Biochemistry, lipids (amino acids, peptides, and proteins), NPC1, Carrier Proteins, Glycoprotein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752eee6816677c93425bc1657351386b
https://doi.org/10.1073/pnas.0308456101 -
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المؤلفون: Haiyan Zheng, David E. Sleat, Mukarram El-Banna, Peter Lobel, Ling Huang, Jennifer A. Wiseman, Dirk F. Moore, Pengling Sun
المصدر: Molecularcellular proteomics : MCP. 12(7)
مصطلحات موضوعية: Proteome, Acid Phosphatase, Mannose, Mannose 6-phosphate, Biochemistry, Analytical Chemistry, chemistry.chemical_compound, Mice, Tandem Mass Spectrometry, Lysosome, medicine, Animals, Molecular Biology, chemistry.chemical_classification, Mice, Knockout, Mannose 6-phosphate receptor, Mannosephosphates, biology, Tartrate-Resistant Acid Phosphatase, Research, Acid phosphatase, Fusion protein, Isoenzymes, medicine.anatomical_structure, chemistry, biology.protein, Glycoprotein, Lysosomes
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75f0ad6815c99389546eeab9fcff6dd
https://pubmed.ncbi.nlm.nih.gov/23478313 -
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المؤلفون: Kwi Hye Kim, Istvan Sohar, Steven U. Walkley, Peter Lobel, Mukarram El-Banna, David E. Sleat, Kostantin Dobrenis
مصطلحات موضوعية: Pathology, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Genetic enhancement, Mice, Transgenic, Disease, Biology, Biochemistry, Aminopeptidases, Article, Mice, Endocrinology, Species Specificity, Neuronal Ceroid-Lipofuscinoses, Internal medicine, Endopeptidases, Genetics, medicine, Lysosomal storage disease, Animals, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Molecular Biology, Gene, Tripeptidyl-Peptidase 1, Gene targeting, Brain, Genetic Therapy, Mitochondrial Proton-Translocating ATPases, medicine.disease, Enzyme assay, Disease Models, Animal, Liver, Gene Targeting, biology.protein, Neuronal ceroid lipofuscinosis, Serine Proteases, Lysosomes, Tripeptidyl-peptidase I activity
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc64bf058281973dbbcd69f6c5145e82
https://europepmc.org/articles/PMC2467442/ -
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المؤلفون: Qi Zhao, Sandy M. Price, Mukarram El-Banna, Gregory R. Stewart, Marco A. Passini, Kwi Hye Kim, Peter Lobel, Qinwen Mao, Richard L. Sidman, Michael M. Shen, Beverly L. Davidson, David E. Sleat, Shannon L. Macauley, Jennifer A. Wiseman
المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience. 24(41)
مصطلحات موضوعية: Male, Cerebellum, Pathology, medicine.medical_specialty, Ataxia, Mice, Transgenic, Degeneration (medical), Neuropathology, Endosomes, Biology, Motor Activity, Aminopeptidases, Tripeptidyl peptidase, Mice, Purkinje Cells, Neuronal Ceroid-Lipofuscinoses, Seizures, Lysosome, Neurobiology of Disease, Endopeptidases, Tremor, medicine, Animals, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Cells, Cultured, Neurons, Tripeptidyl-Peptidase 1, General Neuroscience, Brain, medicine.disease, Tripeptidyl peptidase I, Clone Cells, Mice, Inbred C57BL, Survival Rate, Disease Models, Animal, medicine.anatomical_structure, Phenotype, Gene Targeting, Disease Progression, Neuronal ceroid lipofuscinosis, Female, medicine.symptom, Serine Proteases, Lysosomes, Peptide Hydrolases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd5d8dac510f0d9e17f5dad2cb7d6f0
https://pubmed.ncbi.nlm.nih.gov/15483130
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