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المؤلفون: Mary Aderayo Bamimore, Jeanine E. Roeters van Lennep, Giuliana Fortunato, Vasiliki Mollaki, Eran Leitersdorf, Antonietta D'Angelo, Sonia Shah, Euridiki Drogari, Philippa J. Talmud, Steve E. Humphries, Albert Wiegman, Mahtab Sharifi, Małgorzata Waluś-Miarka, Maria Nicoletta D'Agostino, KaWah Li, Paolo Rubba, Monique T. Mulder, Ros Whittall, Jackie A. Cooper, Ronen Durst, Marta Futema, Olivia Goldberg, Robert A. Hegele, Eric J.G. Sijbrands, Joep C. Defesche, John C. Whittaker

المساهمون: Internal Medicine, Futema, M, Shah, S, Cooper, Ja, Li, K, Whittall, Ra, Sharifi, M, Goldberg, O, Drogari, E, Mollaki, V, Wiegman, A, Defesche, J, D'Agostino, MARIA NICOLETTA, D'Angelo, A, Rubba, PAOLO OSVALDO FEDERICO, Fortunato, Giuliana, Walu?? Miarka, M, Hegele, Ra, Aderayo Bamimore, M, Durst, R, Leitersdorf, E, Mulder, Mt, Roeters van Lennep, Je, Sijbrands, Ej, Whittaker, Jc, Talmud, Pj, Humphries, S. E., Paediatric Metabolic Diseases, ACS - Amsterdam Cardiovascular Sciences, Experimental Vascular Medicine

المصدر: Clinical Chemistry, 61(1), 231-238. American Association for Clinical Chemistry Inc.
Clinical chemistry, 61(1), 231-238. American Association for Clinical Chemistry Inc.

مصطلحات موضوعية: Adult, Male, Canada, Multifactorial Inheritance, Adolescent, Clinical Biochemistry, Single-nucleotide polymorphism, Familial hypercholesterolemia, Biology, medicine.disease_cause, Bioinformatics, Polymorphism, Single Nucleotide, Article, Cohort Studies, Hyperlipoproteinemia Type II, Young Adult, chemistry.chemical_compound, Risk Factors, Polymorphism (computer science), medicine, Humans, Israel, Allele, Child, Gene, Alleles, Apolipoproteins B, Genetics, Mutation, Cholesterol, Serine Endopeptidases, Biochemistry (medical), Case-control study, Cholesterol, LDL, Middle Aged, medicine.disease, Europe, ROC Curve, Receptors, LDL, chemistry, Case-Control Studies, lipids (amino acids, peptides, and proteins), Female, Proprotein Convertases, Proprotein Convertase 9

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b4d47d19b710c509d83e586b9ccd15
https://doi.org/10.1373/clinchem.2014.231365

المؤلفون: Palmiotti A; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Berk KA; Department of Internal Medicine, Division of Endocrinology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Koehorst M; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Hovingh MV; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Pranger AT; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., van Faassen M; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., de Boer JF; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., van der Valk ES; Department of Internal Medicine, Division of Endocrinology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Internal Medicine, Obesity Centre CGG, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., van Rossum EFC; Department of Internal Medicine, Division of Endocrinology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Internal Medicine, Obesity Centre CGG, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Mulder MT; Department of Internal Medicine, Division of Endocrinology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Kuipers F; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department for the Biology of Ageing, European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

المصدر: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2024 Sep; Vol. 26 (9), pp. 4019-4029. Date of Electronic Publication: 2024 Jul 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

مواضيع طبية MeSH: Insulin Resistance* , Bile Acids and Salts*/blood , Bile Acids and Salts*/metabolism , Obesity*/therapy , Obesity*/blood , Obesity*/metabolism , Weight Loss*/physiology , Diabetes Mellitus, Type 2*/blood , Diabetes Mellitus, Type 2*/therapy , Diabetes Mellitus, Type 2*/metabolism, Humans ; Male ; Female ; Middle Aged ; Adult ; Life Style ; Aged ; Cohort Studies

المؤلفون: Tan L; Division of Vascular Medicine and Pharmacology Department of Internal Medicine Erasmus MC Rotterdam The Netherlands.; Clinical Research Center The First Affiliated Hospital of Shantou University Medical College Shantou China., Wang N; Division of Vascular Medicine and Pharmacology Department of Internal Medicine Erasmus MC Rotterdam The Netherlands.; Clinical Research Center The First Affiliated Hospital of Shantou University Medical College Shantou China., Galema-Boers AMH; Division of Vascular Medicine and Pharmacology Department of Internal Medicine Erasmus MC Rotterdam The Netherlands., van Vark-van der Zee L; Division of Vascular Medicine and Pharmacology Department of Internal Medicine Erasmus MC Rotterdam The Netherlands., van Lennep JR; Division of Vascular Medicine and Pharmacology Department of Internal Medicine Erasmus MC Rotterdam The Netherlands., Mulder MT; Division of Vascular Medicine and Pharmacology Department of Internal Medicine Erasmus MC Rotterdam The Netherlands., Lu X; Clinical Research Center The First Affiliated Hospital of Shantou University Medical College Shantou China., Danser AHJ; Division of Vascular Medicine and Pharmacology Department of Internal Medicine Erasmus MC Rotterdam The Netherlands., Verdonk K; Division of Vascular Medicine and Pharmacology Department of Internal Medicine Erasmus MC Rotterdam The Netherlands.

المصدر: MedComm [MedComm (2020)] 2024 Aug 31; Vol. 5 (9), pp. e681. Date of Electronic Publication: 2024 Aug 31 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons, Inc Country of Publication: China NLM ID: 101769925 Publication Model: eCollection Cited Medium: Internet ISSN: 2688-2663 (Electronic) Linking ISSN: 26882663 NLM ISO Abbreviation: MedComm (2020) Subsets: PubMed not MEDLINE

المؤلفون: Tan L; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands. (L.T., A.C.M.K., L.v.V.-v.d.Z., M.T.M., A.H.J.D., K.V.).; Women and Children's Hospital of Chongqing Medical University, China (L.T.).; Clinical Research Center, The First Affiliated Hospital of Shantou University Medical College, China (L.T., X.L.)., van Heugten MH; Nephrology and transplantation, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands. (M.H.H.)., Kluivers ACM; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands. (L.T., A.C.M.K., L.v.V.-v.d.Z., M.T.M., A.H.J.D., K.V.).; Department of Obstetrics and Gynaecology, Erasmus MC, Rotterdam, The Netherlands. (A.C.M.K.)., van Vark-van der Zee L; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands. (L.T., A.C.M.K., L.v.V.-v.d.Z., M.T.M., A.H.J.D., K.V.)., Mulder MT; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands. (L.T., A.C.M.K., L.v.V.-v.d.Z., M.T.M., A.H.J.D., K.V.)., Lu X; Clinical Research Center, The First Affiliated Hospital of Shantou University Medical College, China (L.T., X.L.)., Danser AHJ; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands. (L.T., A.C.M.K., L.v.V.-v.d.Z., M.T.M., A.H.J.D., K.V.)., Verdonk K; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands. (L.T., A.C.M.K., L.v.V.-v.d.Z., M.T.M., A.H.J.D., K.V.).

المصدر: Hypertension (Dallas, Tex. : 1979) [Hypertension] 2024 Jul 30. Date of Electronic Publication: 2024 Jul 30.

نوع المنشور: Letter

بيانات الدورية: Publisher: Lippincott, Williams & Wilkins Country of Publication: United States NLM ID: 7906255 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4563 (Electronic) Linking ISSN: 0194911X NLM ISO Abbreviation: Hypertension Subsets: MEDLINE

المؤلفون: den Hoedt S; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Crivelli SM; Department of Neuroscience, School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands., Dorst-Lagerwerf KY; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Leijten FPJ; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Losen M; Department of Neuroscience, School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands., de Vries HE; Amsterdam UMC, Department of Molecular Cell Biology and Immunology, Amsterdam Neuroscience, VU Medical Center, Amsterdam, the Netherlands., Sijbrands EJG; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Verhoeven AJM; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Martinez-Martinez P; Department of Neuroscience, School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands., Mulder MT; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.

المصدر: Journal of neurochemistry [J Neurochem] 2024 Jul 13. Date of Electronic Publication: 2024 Jul 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE

المؤلفون: Geurts KAM; Department of Internal Medicine, Erasmus University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands., Meijer S; Department of Internal Medicine, Erasmus University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands., Roeters van Lennep JE; Department of Internal Medicine, Erasmus University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands., Wang X; Department of Internal Medicine, Erasmus University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands., Özcan B; Department of Internal Medicine, Erasmus University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands., Voortman G; Department of Internal Medicine, Erasmus University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands., Liu H; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266100, China., Castro Cabezas M; Department of Internal Medicine, Franciscus Gasthuis & Vlietland, Schiedamse Vest 180, 3011 BH Rotterdam, The Netherlands., Berk KA; Department of Internal Medicine, Erasmus University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands., Mulder MT; Department of Internal Medicine, Erasmus University Medical Center, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.

المصدر: Nutrients [Nutrients] 2024 Jun 12; Vol. 16 (12). Date of Electronic Publication: 2024 Jun 12.

نوع المنشور: Journal Article; Randomized Controlled Trial

بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2*/blood , Diabetes Mellitus, Type 2*/drug therapy , Sargassum* , Blood Glucose*/metabolism , Blood Glucose*/drug effects , Fucus*/chemistry, Humans ; Double-Blind Method ; Male ; Female ; Middle Aged ; Pilot Projects ; Overweight/blood ; Feasibility Studies ; Aged ; Adult ; Seaweed ; Hypoglycemic Agents/therapeutic use ; Hypoglycemic Agents/pharmacology ; Edible Seaweeds

SCR Organism: Sargassum fusiforme

المؤلفون: van Drie RWA; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.; Laboratory of Vascular Medicine, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., van de Wouw J; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands., Zandbergen LM; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.; Walter Brendel Center of Experimental Medicine (WBex), University Clinic Munich, 81377 LMU, Munich, Germany., Dehairs J; Laboratory of Lipid Metabolism and Cancer, Department of Oncology, KU Leuven-University of Leuven, Leuven, Belgium., Swinnen JV; Laboratory of Lipid Metabolism and Cancer, Department of Oncology, KU Leuven-University of Leuven, Leuven, Belgium., Mulder MT; Laboratory of Vascular Medicine, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Verhaar MC; Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands., MaassenVanDenBrink A; Laboratory of Vascular Medicine, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Duncker DJ; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands., Sorop O; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands., Merkus D; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands. d.merkus@erasmusmc.nl.; Walter Brendel Center of Experimental Medicine (WBex), University Clinic Munich, 81377 LMU, Munich, Germany. d.merkus@erasmusmc.nl.; Center for Cardiovascular Research (DZHK), Munich Heart Alliance (MHA), Partner Site Munich, 81377, Munich, Germany. d.merkus@erasmusmc.nl.; Interfaculty Center for Endocrine and Cardiovascular Disease Network Modelling and Clinical Transfer (ICONLMU), University Clinic Munich, LMU, Munich, Germany. d.merkus@erasmusmc.nl.

المصدر: Basic research in cardiology [Basic Res Cardiol] 2024 May 25. Date of Electronic Publication: 2024 May 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Steinkopff Country of Publication: Germany NLM ID: 0360342 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-1803 (Electronic) Linking ISSN: 03008428 NLM ISO Abbreviation: Basic Res Cardiol Subsets: MEDLINE

المؤلفون: Martens N; Department of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.; Department of Neuroscience, Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, B-3590 Hasselt, Belgium., Zhan N; Department of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China., Yam SC; Department of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands., Leijten FPJ; Department of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands., Palumbo M; Department of Food and Drug, University of Parma, 43124 Parma, Italy., Caspers M; Department of Microbiology and Systems Biology, The Netherlands Organization for Applied Scientific Research (TNO), 2333 BE Leiden, The Netherlands., Tiane A; Department of Neuroscience, Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, B-3590 Hasselt, Belgium.; Department Psychiatry and Neuropsychology, Division Translational Neuroscience, Mental Health and Neuroscience Institute, Maastricht University, 6200 MD Maastricht, The Netherlands., Friedrichs S; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, D-53127 Bonn, Germany., Li Y; Department of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.; Department of Immunology, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.; Department of Ophthalmology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands., van Vark-van der Zee L; Department of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands., Voortman G; Department of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands., Zimetti F; Department of Food and Drug, University of Parma, 43124 Parma, Italy., Jaarsma D; Department of Neuroscience, Erasmus University Medical Center, 3015 CN Rotterdam, The Netherlands., Verschuren L; Department of Microbiology and Systems Biology, The Netherlands Organization for Applied Scientific Research (TNO), 2333 BE Leiden, The Netherlands., Jonker JW; Department of Pediatrics, Section of Molecular Metabolism and Nutrition, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands., Kuipers F; Department of Pediatrics, Section of Molecular Metabolism and Nutrition, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.; European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen, University of Groningen, 9713 AV Groningen, The Netherlands., Lütjohann D; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, D-53127 Bonn, Germany., Vanmierlo T; Department of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.; Department of Neuroscience, Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, B-3590 Hasselt, Belgium.; Department Psychiatry and Neuropsychology, Division Translational Neuroscience, Mental Health and Neuroscience Institute, Maastricht University, 6200 MD Maastricht, The Netherlands., Mulder MT; Department of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.

المصدر: Nutrients [Nutrients] 2024 May 25; Vol. 16 (11). Date of Electronic Publication: 2024 May 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/drug therapy , Disease Models, Animal* , Dietary Supplements* , Seaweed*/chemistry, Animals ; Mice ; Hippocampus/drug effects ; Hippocampus/metabolism ; Plant Extracts/pharmacology ; Mice, Transgenic ; Sargassum/chemistry ; Humans ; Plaque, Amyloid ; Cholesterol/metabolism ; Cholesterol/blood ; Male ; Amyloid beta-Protein Precursor/genetics ; Amyloid beta-Protein Precursor/metabolism ; tau Proteins/metabolism

المؤلفون: Al Fatly M; Department of Internal Medicine, section of Pharmacology, Vascular and Metabolic Diseases, Erasmus University Medical Center, Rotterdam, the Netherlands., Mulder MT; Department of Internal Medicine, section of Pharmacology, Vascular and Metabolic Diseases, Erasmus University Medical Center, Rotterdam, the Netherlands., Roeters van Lennep J; Department of Internal Medicine, section of Pharmacology, Vascular and Metabolic Diseases, Erasmus University Medical Center, Rotterdam, the Netherlands., Blom HJ; Laboratory of Genetic Metabolic Diseases, Department of Clinical Genetics, Center of lysosomal and metabolic disorders, Erasmus University Medical Center, Rotterdam, The Netherlands., Berk KAC; Department of Internal Medicine, section of Pharmacology, Vascular and Metabolic Diseases, Erasmus University Medical Center, Rotterdam, the Netherlands. k.berk@erasmusmc.nl.; Department of Internal Medicine, section of Dietetics, Erasmus University Medical Center, Rotterdam, The Netherlands. k.berk@erasmusmc.nl.

المصدر: Nutrition journal [Nutr J] 2024 Jan 03; Vol. 23 (1), pp. 2. Date of Electronic Publication: 2024 Jan 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101152213 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2891 (Electronic) Linking ISSN: 14752891 NLM ISO Abbreviation: Nutr J Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2* , Cardiovascular Diseases*, Male ; Adult ; Humans ; Female ; Middle Aged ; Aged ; Overweight ; Obesity ; Diet, Reducing/methods ; Folic Acid ; Vitamin B 12 ; Lipids ; Weight Loss ; Homocysteine