المؤلفون: Durcik, Martina, Cotman, Andrej Emanuel, Toplak, Zan, Mozina, Stefan, Skok, Ziga, Szili, Petra Eva, Czikkely, Marton, Maharramov, Elvin, Vu, Thu Hien, Piras, Maria Vittoria, Zidar, Nace, Ilas, Janez, Zega, Anamarija, Trontelj, Jurij, Pardo, Luis A., Hughes, Diarmaid, 1956, Huseby, Douglas, Berruga-Fernández, Tália, Cao, Sha, Simoff, Ivailo, Svensson, Richard, Korol, Sergiy V., Jin, Zhe, Vicente, Francisca, Ramos, Maria C., Mundy, Julia E. A., Maxwell, Anthony, Stevenson, Clare E. M., Lawson, David M., Glinghammar, Bjorn, Sjostrom, Eva, Bohlin, Martin, Oreskar, Joanna, Alver, Sofie, Janssen, Guido V., Sterk, Geert Jan, Kikelj, Danijel, Pal, Csaba, Tomasic, Tihomir, Masic, Lucija Peterlin

المصدر: Journal of Medicinal Chemistry. 66(6):3968-3994

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-501871
https://doi.org/10.1021/acs.jmedchem.2c01905
https://uu.diva-portal.org/smash/get/diva2:1757322/FULLTEXT01.pdf

المؤلفون: Cotman, Andrej Emanuel, Durcik, Martina, Tiz, Davide Benedetto, Fulgheri, Federica, Secci, Daniela, Sterle, Masa, Mozina, Stefan, Skok, Ziga, Zidar, Nace, Zega, Anamarija, Ilas, Janez, Masic, Lucija Peterlin, Tomasic, Tihomir, Hughes, Diarmaid, 1956, Huseby, Douglas L., Cao, Sha, Garoff, Linnea, Fernandez, Talia Berruga, Giachou, Paraskevi, Crone, Lisa, Simoff, Ivailo, Svensson, Richard, Birnir, Bryndis, Korol, Sergiy, Jin, Zhe, Vicente, Francisca, Ramos, Maria C., de la Cruz, Mercedes, Glinghammar, Bjorn, Lenhammar, Lena, Henderson, Sara R., Mundy, Julia E. A., Maxwell, Anthony, Stevenson, Clare E. M., Lawson, David M., Janssen, Guido V., Sterk, Geert Jan, Kikelj, Danijel

المصدر: Journal of Medicinal Chemistry. 66(2):1380-1425

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-497765
https://doi.org/10.1021/acs.jmedchem.2c01597
https://uu.diva-portal.org/smash/get/diva2:1742239/FULLTEXT01.pdf

المؤلفون: Feng, Lipeng, Mundy, Julia E. A., Stevenson, Clare E. M., Mitchenall, Lesley A., Lawson, David M., Mi, Kaixia, Maxwell, Anthony

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2021 Mar . 118(11), 1-12.

URL الوصول: https://www.jstor.org/stable/27027618

المؤلفون: Cotman, Andrej Emanuel, Durcik, Martina, Benedetto Tiz, Davide, Fulgheri, Federica, Secci, Daniela, Sterle, Maša, Možina, Štefan, Skok, Žiga, Zidar, Nace, Zega, Anamarija, Ilaš, Janez, Peterlin Mašič, Lucija, Tomašič, Tihomir, Hughes, Diarmaid, Huseby, Douglas L., Cao, Sha, Garoff, Linnéa, Berruga Fernández, Talía, Giachou, Paraskevi, Crone, Lisa, Simoff, Ivailo, Svensson, Richard, Birnir, Bryndis, Korol, Sergiy V., Jin, Zhe, Vicente, Francisca, Ramos, Maria C., de la Cruz, Mercedes, Glinghammar, Björn, Lenhammar, Lena, Henderson, Sara R., Mundy, Julia E. A., Maxwell, Anthony, Stevenson, Clare E. M., Lawson, David M., Janssen, Guido V., Sterk, Geert Jan, Kikelj, Danijel

المصدر: Journal of Medicinal Chemistry; January 2023, Vol. 66 Issue: 2 p1380-1425, 46p

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المؤلفون: Lipeng Feng, Mundy, Julia E. A., Stevenson, Clare E. M., Mitchenall, Lesley A., Lawson, David M., Kaixia Mi, Maxwell, Anthony

المصدر: Proceedings of the National Academy of Sciences of the United States of America; 3/16/2021, Vol. 118 Issue 11, p1-12, 12p

مصطلحات موضوعية: DNA topoisomerase II, DOUBLE-strand DNA breaks, PROTEINS, MYCOBACTERIUM smegmatis, COMMERCIAL products, X-ray crystallography

المؤلفون: Zidar N; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Emanuel Cotman A; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Sinnige W; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia; Vrije Universiteit Amsterdam, Medicinal Chemistry Division, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands., Benek O; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Barančokova M; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Zega A; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Peterlin Mašič L; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Tomašič T; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Ilaš J; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia., Henderson SR; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK., Mundy JEA; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK., Maxwell A; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK., Stevenson CEM; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK., Lawson DM; Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK., Jan Sterk G; Vrije Universiteit Amsterdam, Medicinal Chemistry Division, De Boelelaan 1108, 1081 HZ Amsterdam, the Netherlands., Tosso R; Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, Instituto Multidisciplinario de Investigaciones Biológicas (IMIBIO-SL), Ejercito de los Andes 950, 5700 San Luis, Argentina., Gutierrez L; Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, Instituto Multidisciplinario de Investigaciones Biológicas (IMIBIO-SL), Ejercito de los Andes 950, 5700 San Luis, Argentina., Enriz RD; Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, Instituto Multidisciplinario de Investigaciones Biológicas (IMIBIO-SL), Ejercito de los Andes 950, 5700 San Luis, Argentina. Electronic address: danielenriz@gmail.com., Kikelj D; University of Ljubljana, Faculty of Pharmacy, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia. Electronic address: danijel.kikelj@ffa.uni-lj.si.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2024 Jul 15; Vol. 109, pp. 117798. Date of Electronic Publication: 2024 Jun 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Topoisomerase II Inhibitors*/pharmacology , Topoisomerase II Inhibitors*/chemistry , Topoisomerase II Inhibitors*/chemical synthesis , DNA Gyrase*/metabolism , DNA Gyrase*/chemistry , Escherichia coli*/enzymology , Escherichia coli*/drug effects, Binding Sites ; Structure-Activity Relationship ; Benzothiazoles/chemistry ; Benzothiazoles/pharmacology ; Benzothiazoles/chemical synthesis ; Adenosine Triphosphate/metabolism ; Adenosine Triphosphate/chemistry ; Molecular Structure ; Quantum Theory ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/chemical synthesis ; Models, Molecular