المؤلفون: Ashmore, T, Roberts, LD, Morash, AJ, Kotwica, AO, Finnerty, J, West, JA, Murfitt, SA, Fernandez, BO, Branco, C, Cowburn, AS, Clarke, K, Johnson, RS, Feelisch, M, Griffin, JL, Murray, AJ

المصدر: BMC biology. 13:110

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:132633190

المؤلفون: McNally BD; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK., Ashley DF; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK., Hänschke L; Life & Medical Sciences Institute (LIMES) Development, Genetics & Molecular Physiology Unit, University of Bonn, Carl-Troll-Straße, 31, 53115, Bonn, Germany., Daou HN; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK., Watt NT; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK., Murfitt SA; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK., MacCannell ADV; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK., Whitehead A; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK., Bowen TS; Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Sanders FWB; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK., Vacca M; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK.; Clinica Medica 'Frugoni', Interdisciplinar Department of Medicine, University of Bari 'Aldo Moro', Bari, Italy., Witte KK; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK., Davies GR; Bioscience Metabolism, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Bauer R; Life & Medical Sciences Institute (LIMES) Development, Genetics & Molecular Physiology Unit, University of Bonn, Carl-Troll-Straße, 31, 53115, Bonn, Germany., Griffin JL; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Roberts LD; School of Medicine, University of Leeds, Leeds, LS2 9JT, UK. L.D.Roberts@leeds.ac.uk.

المصدر: Nature communications [Nat Commun] 2022 Apr 01; Vol. 13 (1), pp. 1748. Date of Electronic Publication: 2022 Apr 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Ceramides*/metabolism , Endoplasmic Reticulum Stress*/physiology, Animals ; Endoplasmic Reticulum/metabolism ; Mice ; Muscle, Skeletal/metabolism ; Unfolded Protein Response

المؤلفون: Whitehead A; School of Medicine, University of Leeds, Leeds, UK., Krause FN; Department of Biochemistry, University of Cambridge, Cambridge, UK., Moran A; School of Medicine, University of Leeds, Leeds, UK., MacCannell ADV; School of Medicine, University of Leeds, Leeds, UK., Scragg JL; School of Medicine, University of Leeds, Leeds, UK., McNally BD; Department of Biochemistry, University of Cambridge, Cambridge, UK., Boateng E; School of Medicine, University of Leeds, Leeds, UK., Murfitt SA; Department of Biochemistry, University of Cambridge, Cambridge, UK., Virtue S; Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Wright J; School of Medicine, University of Leeds, Leeds, UK., Garnham J; School of Medicine, University of Leeds, Leeds, UK., Davies GR; Bioscience Metabolism, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Dodgson J; Phenotypic Screening and High Content Imaging, Antibody Discovery & Protein Engineering, R&D, AstraZeneca, Cambridge, UK., Schneider JE; School of Medicine, University of Leeds, Leeds, UK., Murray AJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK., Church C; Bioscience Metabolism, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Vidal-Puig A; Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Witte KK; School of Medicine, University of Leeds, Leeds, UK., Griffin JL; Department of Biochemistry, University of Cambridge, Cambridge, UK., Roberts LD; School of Medicine, University of Leeds, Leeds, UK. L.D.Roberts@leeds.ac.uk.

المصدر: Nature communications [Nat Commun] 2021 Mar 26; Vol. 12 (1), pp. 1905. Date of Electronic Publication: 2021 Mar 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Adipose Tissue, Beige/*metabolism , Adipose Tissue, Brown/*metabolism , Energy Metabolism/*genetics , Homeostasis/*genetics , Signal Transduction/*genetics, Adipocytes, Brown/metabolism ; Adipocytes, White/metabolism ; Adipose Tissue, Beige/cytology ; Adipose Tissue, Brown/cytology ; Animals ; Cell Line ; Cells, Cultured ; Chromatography, Liquid ; Gas Chromatography-Mass Spectrometry ; Gene Expression Profiling/methods ; Humans ; Male ; Mass Spectrometry ; Metabolomics/methods ; Mice, Inbred C57BL ; Mice

المؤلفون: McNally BD; Medical Research Council - Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, U.K.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K., Moran A; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, U.K., Watt NT; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, U.K., Ashmore T; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, U.K., Whitehead A; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, U.K., Murfitt SA; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K., Kearney MT; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, U.K., Cubbon RM; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, U.K., Murray AJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, U.K., Griffin JL; Medical Research Council - Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, U.K.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, U.K., Roberts LD; Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, U.K. l.d.roberts@leeds.ac.uk.

المصدر: Diabetes [Diabetes] 2020 May; Vol. 69 (5), pp. 893-901. Date of Electronic Publication: 2020 Feb 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE

مواضيع طبية MeSH: Adipose Tissue, White/*drug effects , Adipose Tissue, White/*metabolism , Glucose/*metabolism , Nitrates/*pharmacology , Nitric Oxide/*metabolism , Xanthine Dehydrogenase/*metabolism, Adipocytes/drug effects ; Adipocytes/metabolism ; Animals ; Cells, Cultured ; Gene Expression Regulation, Enzymologic/drug effects ; Gene Expression Regulation, Enzymologic/physiology ; Male ; Metabolism ; Nitrates/administration & dosage ; Oxidation-Reduction ; Rats ; Rats, Wistar

المؤلفون: Murfitt SA; Department of Biochemistry, University of Cambridge , The Sanger Building, 80 Tennis Court Road, Cambridge CB2 1GA, U.K., Zaccone P; Department of Pathology, University of Cambridge , Tennis Court Road, Cambridge CB2 1QP, U.K., Wang X; Department of Biochemistry, University of Cambridge , The Sanger Building, 80 Tennis Court Road, Cambridge CB2 1GA, U.K., Acharjee A; Medical Research Council Human Nutrition Research, The Elsie Widdowson Laboratory , 120 Fulbourn Road, Cambridge CB1 9NL, U.K., Sawyer Y; Department of Pathology, University of Cambridge , Tennis Court Road, Cambridge CB2 1QP, U.K., Koulman A; Medical Research Council Human Nutrition Research, The Elsie Widdowson Laboratory , 120 Fulbourn Road, Cambridge CB1 9NL, U.K., Roberts LD; Medical Research Council Human Nutrition Research, The Elsie Widdowson Laboratory , 120 Fulbourn Road, Cambridge CB1 9NL, U.K., Cooke A; Department of Pathology, University of Cambridge , Tennis Court Road, Cambridge CB2 1QP, U.K., Griffin JL; Department of Biochemistry, University of Cambridge , The Sanger Building, 80 Tennis Court Road, Cambridge CB2 1GA, U.K.; Medical Research Council Human Nutrition Research, The Elsie Widdowson Laboratory , 120 Fulbourn Road, Cambridge CB1 9NL, U.K.

المصدر: Journal of proteome research [J Proteome Res] 2018 Mar 02; Vol. 17 (3), pp. 946-960. Date of Electronic Publication: 2018 Feb 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3907 (Electronic) Linking ISSN: 15353893 NLM ISO Abbreviation: J Proteome Res Subsets: MEDLINE

مواضيع طبية MeSH: Lipid Metabolism*, Diabetes Mellitus, Type 1/*metabolism , Islets of Langerhans/*metabolism , Prediabetic State/*metabolism , Purines/*metabolism , Tryptophan/*metabolism, Animals ; Autoimmunity ; Chromatography, Liquid ; Diabetes Mellitus, Type 1/immunology ; Diabetes Mellitus, Type 1/pathology ; Discriminant Analysis ; Disease Models, Animal ; Female ; Gas Chromatography-Mass Spectrometry ; Gene Expression ; Histocompatibility Antigens Class II/genetics ; Histocompatibility Antigens Class II/immunology ; Islets of Langerhans/immunology ; Islets of Langerhans/pathology ; Kynurenic Acid/metabolism ; Lysophospholipids/metabolism ; Metabolomics/methods ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Mice, Transgenic ; Prediabetic State/immunology ; Prediabetic State/pathology ; Principal Component Analysis ; Protein Multimerization

المؤلفون: Roberts LD; Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, U.K. l.d.roberts@leeds.ac.uk.; Medical Research Council-Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, U.K.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K., Ashmore T; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, U.K., McNally BD; Medical Research Council-Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, U.K.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K., Murfitt SA; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K., Fernandez BO; Faculty of Medicine, Clinical and Experimental Sciences, University of Southampton, Southampton General Hospital, Southampton, U.K., Feelisch M; Faculty of Medicine, Clinical and Experimental Sciences, University of Southampton, Southampton General Hospital, Southampton, U.K., Lindsay R; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, U.K., Siervo M; Human Nutrition Research Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, U.K., Williams EA; Human Nutrition Unit, Department of Oncology, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, U.K., Murray AJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, U.K., Griffin JL; Medical Research Council-Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, U.K.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, U.K.

المصدر: Diabetes [Diabetes] 2017 Mar; Vol. 66 (3), pp. 674-688. Date of Electronic Publication: 2016 Dec 27.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE

مواضيع طبية MeSH: Physical Conditioning, Animal*, Fibronectins/*drug effects , Muscle Fibers, Skeletal/*drug effects , Nitrates/*pharmacology , Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/*drug effects, Adipocytes/drug effects ; Adipocytes/metabolism ; Aged ; Aminoisobutyric Acids ; Animals ; Beta vulgaris ; Chromatography, Liquid ; Double-Blind Method ; Female ; Fibronectins/metabolism ; Fruit and Vegetable Juices ; Gas Chromatography-Mass Spectrometry ; Growth Hormone/metabolism ; Humans ; Immunohistochemistry ; In Vitro Techniques ; Insulin Resistance ; Male ; Mass Spectrometry ; Mice ; Mice, Transgenic ; Middle Aged ; Muscle Fibers, Fast-Twitch/drug effects ; Muscle Fibers, Fast-Twitch/metabolism ; Muscle Fibers, Skeletal/metabolism ; Muscle Fibers, Slow-Twitch/drug effects ; Muscle Fibers, Slow-Twitch/metabolism ; Muscle, Skeletal/drug effects ; Muscle, Skeletal/metabolism ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/genetics ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; Rats ; Rats, Wistar ; Transcriptome ; gamma-Aminobutyric Acid/drug effects ; gamma-Aminobutyric Acid/metabolism

المؤلفون: Roberts LD; Medical Research Council - Human Nutrition Research, Elsie Widdowson Laboratory, 120 Fulbourn Road, Cambridge, CB2 9NL, UK.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, 80 Tennis Court Road, Old Addenbrooke's Site, Cambridge, CB2 1GA, UK., Ashmore T; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, 80 Tennis Court Road, Old Addenbrooke's Site, Cambridge, CB2 1GA, UK.; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3EG, UK., Kotwica AO; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3EG, UK., Murfitt SA; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, 80 Tennis Court Road, Old Addenbrooke's Site, Cambridge, CB2 1GA, UK., Fernandez BO; Faculty of Medicine, Clinical & Experimental Sciences, University of Southampton, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK., Feelisch M; Faculty of Medicine, Clinical & Experimental Sciences, University of Southampton, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK., Murray AJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3EG, UK., Griffin JL; Medical Research Council - Human Nutrition Research, Elsie Widdowson Laboratory, 120 Fulbourn Road, Cambridge, CB2 9NL, UK.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, 80 Tennis Court Road, Old Addenbrooke's Site, Cambridge, CB2 1GA, UK.

المصدر: Diabetes [Diabetes] 2015 Feb; Vol. 64 (2), pp. 471-484. Date of Electronic Publication: 2014 Sep 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE

مواضيع طبية MeSH: Adipose Tissue, White/*drug effects , Adipose Tissue, White/*metabolism , Nitrates/*metabolism , Nitrates/*pharmacology , Nitric Oxide/*metabolism , Nitrites/*metabolism, Adipocytes, Brown/physiology ; Adipocytes, White/drug effects ; Adipocytes, White/physiology ; Adipose Tissue, Brown ; Animals ; Cells, Cultured ; Cyclic GMP ; Cyclic GMP-Dependent Protein Kinases ; Dose-Response Relationship, Drug ; Male ; Mice ; Mice, Inbred C57BL ; Rats ; Rats, Wistar

المؤلفون: Castro C; Department of Biochemistry and the Cambridge Systems Biology Centre, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK., Krumsiek J, Lehrbach NJ, Murfitt SA, Miska EA, Griffin JL

المصدر: Molecular bioSystems [Mol Biosyst] 2013 Jul; Vol. 9 (7), pp. 1632-42. Date of Electronic Publication: 2013 Mar 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101251620 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-2051 (Electronic) Linking ISSN: 17422051 NLM ISO Abbreviation: Mol Biosyst Subsets: MEDLINE

مواضيع طبية MeSH: Metabolomics*/methods , Mutant Proteins* , Signal Transduction*, Caenorhabditis elegans/*genetics , Caenorhabditis elegans/*metabolism , Caenorhabditis elegans Proteins/*metabolism , Receptor, Insulin/*metabolism, Amino Acids/metabolism ; Animals ; Caenorhabditis elegans Proteins/genetics ; Fatty Acids/metabolism ; Metabolic Networks and Pathways ; Receptor, Insulin/genetics ; Temperature