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المؤلفون: Leif A, Havton, Natalia P, Biscola, Esther, Stern, Plamen V, Mihaylov, Chandrashekhar A, Kubal, John M, Wo, Anita, Gupta, Elizabeth, Baronowsky, Matthew P, Ward, Deborah M, Jaffey, Terry L, Powley
المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reportsمصطلحات موضوعية: Adult, Male, Nerve Fibers, Unmyelinated, Multidisciplinary, Myelin biology and repair, Science, Vagus Nerve, Middle Aged, Nerve Fibers, Myelinated, Article, Microscopy, Electron, nervous system, Limit of Detection, Humans, Medicine, Female, Peripheral nervous system, Myelin Sheath
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2
المؤلفون: C. Bartlett, Melinda Fitzgerald, Sarah C Hellewell, Alexander J Wright, Brittney R. Lins, Terence McGonigle, Chidozie C. Anyaegbu, Melissa Papini, Lillian M. Toomey, Andrew Warnock
المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reportsمصطلحات موضوعية: Male, Pathology, medicine.medical_specialty, Multiple Sclerosis, Myelin biology and repair, Science, Oligodendrocyte progenitor, Article, Corpus Callosum, Cuprizone, Mice, medicine, Demyelinating disease, Animals, Gliosis, Chelating Agents, Inflammation, Multidisciplinary, Chemistry, Multiple sclerosis, Body Weight, Reproducibility of Results, medicine.disease, Animal Feed, Astrogliosis, Mice, Inbred C57BL, Disease Models, Animal, Oligodendroglia, Astrocytes, Medicine, Microglia, DNA Damage, Demyelinating Diseases
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3
المؤلفون: Katy Lh Marshall-Phelps, Rebecca Frawley, Boguslawa Sadowski, Wiebke Möbius, Damien Marechal, Sunniva M. K. Bøstrand, Yong-hui Jiang, David A. Lyons, Patrizia Casaccia, Sarah Moyon, Dennis Huang, Linde Kegel
المساهمون: Neuroscience Initiative Advanced Science Research Center, CUNY, 85 St Nicholas Terrace, New York, NY 10031, USA, Centre for Discovery Brain Sciences, Edinburgh, UK, Department of Neurogenetics, Göttingen, Germany. 4 Electron Microscopy Core Unit, Max-Planck-Institute of Experimental Medicine, Göttingen, Germany., Department of Neurobiology and Pediatrics, Duke University School of Medicine, Durham, NC, USA
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications, 2023, 12 (1), pp.3359. ⟨10.1038/s41467-021-23735-3⟩مصطلحات موضوعية: 0301 basic medicine, DNA Hydroxymethylation, Transgene, Myelin biology and repair, [SDV]Life Sciences [q-bio], Science, General Physics and Astronomy, Mice, Transgenic, Biology, medicine.disease_cause, Molecular neuroscience, Article, General Biochemistry, Genetics and Molecular Biology, Animals, Genetically Modified, 03 medical and health sciences, Myelin, 0302 clinical medicine, Proto-Oncogene Proteins, medicine, Animals, Solute Carrier Family 12, Member 2, RNA-Seq, Remyelination, Cells, Cultured, Myelin Sheath, Zebrafish, Mice, Knockout, Mutation, Multidisciplinary, DNA methylation, Gene Expression Profiling, General Chemistry, Oligodendrocyte, Solute carrier family, Cell biology, DNA-Binding Proteins, Oligodendroglia, 030104 developmental biology, medicine.anatomical_structure, nervous system, 030217 neurology & neurosurgery
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4
المؤلفون: Piotr Walczak, Manuel Guizar-Sicairos, Jennifer A. McNab, Marianne Liebi, Mark Augath, Michael Zeineh, Timothy M. Shepherd, Aileen Schroeter, Aleezah Balolia, Lin Yang, Markus Rudin, Marios Georgiadis, Oliver Bunk, Zirui Gao, Els Fieremans, Phillip DiGiacomo, Ivan Rajkovic, Christoph Leuze, Valerio Zerbi, Jiangyang Zhang, Dmitry S. Novikov, Benjamin Ades-Aron, Sung-Lyoung Kim, Jelle Veraart, Choong H. Lee, Thomas M. Weiss, Stefan Sommer, Gergely David, Shirish Chodankar
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, 12 (1)
Nature Communicationsمصطلحات موضوعية: Central Nervous System, Male, 0301 basic medicine, Myelin biology and repair, General Physics and Astronomy, Imaging techniques, Imaging, Mice, Myelin, 0302 clinical medicine, Mouse Spinal Cord, Axon, Myelin Sheath, Mice, Knockout, Multidisciplinary, Chemistry, Brain, SAXS, Magnetic Resonance Imaging, 3. Good health, medicine.anatomical_structure, Spinal Cord, Child, Preschool, Female, Tomography, Myelin Proteins, Nervous system, Multiple Sclerosis, Nanostructure, Brain development, Science, Neuroimaging, Proof of Concept Study, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Scattering, Small Angle, medicine, Animals, Humans, X-Rays, Nervous tissue, fungi, General Chemistry, Axons, Nanostructures, Mice, Inbred C57BL, 030104 developmental biology, nervous system, Molecular imaging, Tomography, X-Ray Computed, Neuroscience, 030217 neurology & neurosurgery
وصف الملف: application/application/pdf
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المؤلفون: Michael Polydefkis, Jing Zhu, Yuan Sun, Ahmet Hoke, Ruifa Mi, Osefame Ewaleifoh, Josh Wei, Ying Liu
المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reportsمصطلحات موضوعية: medicine.medical_specialty, Diabetic neuropathy, Myelin biology and repair, Science, Neural Conduction, 030209 endocrinology & metabolism, Hindlimb, Neuroprotection, DNA, Mitochondrial, Article, Diabetes Mellitus, Experimental, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Ethoxyquin, Diabetic Neuropathies, Internal medicine, medicine, Animals, Autonomic nervous system, Multidisciplinary, business.industry, medicine.disease, Sciatic Nerve, Db/db Mouse, Disease Models, Animal, Endocrinology, medicine.anatomical_structure, Peripheral neuropathy, Neuroprotective Agents, chemistry, Diabetes Mellitus, Type 2, Peripheral nervous system, Mutation, Diseases of the nervous system, Medicine, Sciatic nerve, business, Somatic system, 030217 neurology & neurosurgery
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المؤلفون: Brighton Payne, Karen M. Gorse, Sabrina Lee, Phillip Stone, Audrey D. Lafrenaye, Jane Ryu
المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Scientific Reportsمصطلحات موضوعية: Male, Pathology, medicine.medical_specialty, Traumatic brain injury, Myelin biology and repair, Science, Neuroimmunology, Article, Rats, Sprague-Dawley, Myelin, Amyloid beta-Protein Precursor, Brain Injuries, Traumatic, Brain Injuries, Diffuse, Medicine, Animals, Neuroinflammation, Myelin Sheath, Multidisciplinary, biology, Microglia, business.industry, Myelin Basic Protein, medicine.disease, Oligodendrocyte, Cellular neuroscience, Myelin basic protein, Buprenorphine, Rats, Analgesics, Opioid, medicine.anatomical_structure, nervous system, Astrocytes, biology.protein, Cytokines, Diseases of the nervous system, business, Astrocyte, Neuroglia, Neuroscience
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المؤلفون: Kleopas A. Kleopa, Christina Tryfonos, Alexia Kagiava, Irene Sargiannidou, Amanda Heslegrave, Christos Karaiskos, Henrik Zetterberg, Rita Horvath, Matthew J. Jennings, Marina Stavrou, Mary M. Reilly, Jan Richter, Christina Christodoulou
المساهمون: Kagiava, Alexia [0000-0002-3903-1299], Kleopa, Kleopas A [0000-0002-4103-8094], Apollo - University of Cambridge Repository, Kleopa, Kleopas A. [0000-0002-4103-8094]
المصدر: Gene Therapy
مصطلحات موضوعية: 82/29, Pathology, medicine.medical_specialty, 631/378/2606, Myelin biology and repair, Genetic enhancement, Schwann cell, Inflammation, 631/378/1959, Biology, Article, Connexins, Mice, Myelin, 692/53, Charcot-Marie-Tooth Disease, Genetics, medicine, 692/699/375, Animals, Tissue Distribution, Molecular Biology, Mice, Knockout, Myelin protein zero, 101/28, 64/110, Genetic Therapy, medicine.anatomical_structure, Peripheral nervous system, 13/51, Molecular Medicine, Biomarker (medicine), Schwann Cells, Sciatic nerve, medicine.symptom, Neurological disorders, Biomarkers
وصف الملف: application/pdf; text/xml; application/zip
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المؤلفون: John Patrick Aggleton, Emma Jane Kidd, Jilu P. Mole, John Evans, Claudia Metzler-Baddeley, Fabrizio Fasano, Rebecca Sims
المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-25 (2020)
Scientific Reportsمصطلحات موضوعية: Adult, Male, 0301 basic medicine, Neurite, Myelin biology and repair, Apolipoprotein E4, Thalamus, Hippocampus, lcsh:Medicine, Blood Pressure, Grey matter, Asymptomatic, Article, 03 medical and health sciences, Myelin, 0302 clinical medicine, Risk Factors, medicine, Humans, Dementia, Prospective Studies, Gray Matter, lcsh:Science, Aged, Multidisciplinary, Cognitive ageing, business.industry, Papez circuit, Interleukin-8, lcsh:R, Middle Aged, Neural ageing, medicine.disease, Magnetic Resonance Imaging, White Matter, C-Reactive Protein, 030104 developmental biology, medicine.anatomical_structure, Female, lcsh:Q, medicine.symptom, business, Neuroscience, Biomarkers, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Douglas N. Greve, Sreekanth Kura, Ichun Anderson Chen, Caroline Magnain, Hui Wang, Bruce Fischl, Shuaibin Chang, Jean C. Augustinack, David A. Boas, Divya Varadarajan, Jiarui Yang
المصدر: Scientific Reports
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)مصطلحات موضوعية: Adult, Male, Scattering coefficient, Science, Myelin biology and repair, Neuroimaging, Article, Micrometre, Myelin, Imaging, Three-Dimensional, Optical coherence tomography, Predictive Value of Tests, Cadaver, medicine, Humans, Scattering, Radiation, Myelin Sheath, Aged, Neurons, Physics, Multidisciplinary, medicine.diagnostic_test, Scattering, Lasers, Resolution (electron density), Brain, Reproducibility of Results, Human brain, Middle Aged, Cellular neuroscience, medicine.anatomical_structure, nervous system, Medicine, Female, Neuron, Neuroscience, Tomography, Optical Coherence
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10Rab35-regulated lipid turnover by myotubularins represses mTORC1 activity and controls myelin growth
المؤلفون: Kerstin Klinkert, Volker Haucke, Alessandra Bolino, Genaro Patino-Lopez, Linda Sawade, Francina Langa-Vives, Federica Grandi, Marianna Mignanelli, Roberta Di Guardo, Arnaud Echard
المساهمون: Leibniz Forschungsinstitut für Molekulare Pharmakolgie = Leibniz Institute for Molecular Pharmacology [Berlin, Allemagne] (FMP), Leibniz Association, IRCCS Ospedale San Raffaele [Milan, Italy], Universita Vita Salute San Raffaele = Vita-Salute San Raffaele University [Milan, Italie] (UniSR), Hospital Infantil de México Federico Gómez (HIMFG), Trafic membranaire et Division cellulaire - Membrane Traffic and Cell Division, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Sorbonne Université (SU), Centre d'Ingénierie génétique murine - Mouse Genetics Engineering Center (CIGM), Institut Pasteur [Paris] (IP), Freie Universität Berlin, Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], Supported by grants from the German Research Foundation (DFG) (SFB958/A01 and HA2686/15-1 to V.H.), from Muscular Dystrophy Association (MDA574294) and AFM-Telethon France (#21528) to A.B., V.H. and A.B. are funded by E-Rare-3 JTC 2017 and are members of the eRARE Consortium 'Treat-MTMs'. Part of this work has been supported by Institut Pasteur and CNRS to A.E., K.K. was supported by the Pasteur - Paris University (PPU) International PhD Program and by and a fellowship from FRM (FDT20150532389)., Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris]
المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications, 2020, 11 (1), pp.2835. ⟨10.1038/s41467-020-16696-6⟩
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.2835. ⟨10.1038/s41467-020-16696-6⟩مصطلحات موضوعية: 0301 basic medicine, Myelin biology and repair, General Physics and Astronomy, GTPase, mTORC1, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], Small GTPases, chemistry.chemical_compound, Myelin, 0302 clinical medicine, Charcot-Marie-Tooth Disease, Gene Knock-In Techniques, Lipid signalling, lcsh:Science, Myelin Sheath, Multidisciplinary, Hyperactivation, Chemistry, Protein Tyrosine Phosphatases, Non-Receptor, Phenotype, 3. Good health, Cell biology, medicine.anatomical_structure, Signal Transduction, congenital, hereditary, and neonatal diseases and abnormalities, Science, Primary Cell Culture, Down-Regulation, Mice, Transgenic, Mechanistic Target of Rapamycin Complex 1, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, medicine, Animals, Humans, Phosphatidylinositol, Gene, General Chemistry, Nutrient signalling, Lipid Metabolism, nervous system diseases, 030104 developmental biology, HEK293 Cells, rab GTP-Binding Proteins, Astrocytes, Mutation, lcsh:Q, 030217 neurology & neurosurgery, Biogenesis, HeLa Cells