المؤلفون: Gilles Lalmanach, Ahlame Saidi, Paul Bigot, Thibault Chazeirat, Fabien Lecaille, Mylène Wartenberg

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 6, p 1944 (2020)

مصطلحات موضوعية: cathepsin, chronic obstructive pulmonary disease (copd), cysteine, cysteine protease, lung inflammation, oxidation, proteolysis, thiol, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/21/6/1944; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/6c7b4a393cfe4a20aea2f64def0236b0

المؤلفون: Vincent Aucagne, Mylène Wartenberg, Gilles Lalmanach, Jean-Baptiste Madinier, Seda Seren, Fabien Lecaille, Guy Ilango, Ahlame Saidi, Brice Korkmaz

المساهمون: Centre d’Etude des Pathologies Respiratoires (CEPR), UMR 1100 (CEPR), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de biophysique moléculaire (CBM), Université d'Orléans (UO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Plateforme IBISA de Microscopie Electronique [CHRU de Tours] (UNIV Tours), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)-Université de Tours (UT), Aucagne, Vincent, Lalmanach, Gilles

المصدر: Bioconjugate Chemistry
Bioconjugate Chemistry, 2021, 32 (8), pp.1782-1790. ⟨10.1021/acs.bioconjchem.1c00267⟩

مصطلحات موضوعية: Proteinase 3, Spectrophotometry, Infrared, Cell Survival, Neutrophils, Myeloblastin, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Near-infrared fluorescence (NIRF), Cathepsin G, Gene Expression Regulation, Enzymologic, Neutrophil Activation, Cathepsin, law.invention, chemistry.chemical_compound, Confocal microscopy, law, Elastase, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, Dark quencher, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], [SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], Fluorescent Dyes, Pharmacology, Microscopy, Confocal, Molecular Structure, biology, Neutrophil serine protease (NSP), Ionomycin, Organic Chemistry, Fluorescence, Förster resonance energy transfer, chemistry, Neutrophil elastase, biology.protein, Biophysics, Norvaline, Biotechnology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b3ebee5c9187042616e5df44f7be9b
https://doi.org/10.1021/acs.bioconjchem.1c00267

المؤلفون: Lydie Nadal-Desbarats, Pierre-Marie Andrault, Gilles Lalmanach, Ahlame Saidi, Paul Bigot, Mylène Wartenberg, Fabien Lecaille

المساهمون: Centre d’Etude des Pathologies Respiratoires (CEPR), UMR 1100 (CEPR), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Imagerie et cerveau (iBrain - Inserm U1253 - UNIV Tours ), Lalmanach, Gilles, Pathologies Respiratoires : Protéolyse et Aérosolthérapie, Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d'Etude des Pathologies Respiratoires (CEPR), UMR 1100. Equipe 2 'Mécanismes Protéolytiques dans l'Inflammation' (CEPR. Equipe 2), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Tours (UT)

المصدر: Free Radical Biology and Medicine
Free Radical Biology and Medicine, Elsevier, 2020, 150, pp.53-65. ⟨10.1016/j.freeradbiomed.2020.02.013⟩

مصطلحات موضوعية: 0301 basic medicine, Protein Carbonylation, [SDV]Life Sciences [q-bio], Sulfinic acid, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Smoke, Physiology (medical), Tobacco, Hydrogen peroxide, ComputingMilieux_MISCELLANEOUS, chemistry.chemical_classification, Smoking, Acrolein, Glutathione, Cathepsins, 3. Good health, [SDV] Life Sciences [q-bio], 030104 developmental biology, chemistry, Sulfenic acid, Oxidation-Reduction, 030217 neurology & neurosurgery, Peroxynitrite, Cysteine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ee722b0e527abc3c86ea7d05e86889
https://hal.archives-ouvertes.fr/hal-03677268

المؤلفون: Ahlame Saidi, Thibault Chazeirat, Paul Bigot, Mylène Wartenberg, Fabien Lecaille, Gilles Lalmanach

المساهمون: Centre d’Etude des Pathologies Respiratoires (CEPR), UMR 1100 (CEPR), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM), Lalmanach, Gilles

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 6, p 1944 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (6), pp.1944. ⟨10.3390/ijms21061944⟩

مصطلحات موضوعية: Review, medicine.disease_cause, lcsh:Chemistry, 0302 clinical medicine, Catalytic Domain, Papain, cysteine protease, [SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], cysteine, lcsh:QH301-705.5, ComputingMilieux_MISCELLANEOUS, Spectroscopy, chemistry.chemical_classification, 0303 health sciences, biology, medicine.diagnostic_test, Chemistry, thiol, General Medicine, Oxidants, Cysteine protease, 3. Good health, Computer Science Applications, Cysteine Endopeptidases, Biochemistry, 030220 oncology & carcinogenesis, Thiol, Oxidation-Reduction, proteolysis, oxidation, Proteolysis, Catalysis, chronic obstructive pulmonary disease (copd), Inorganic Chemistry, 03 medical and health sciences, medicine, biochemistry, Animals, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, cathepsin, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], Physical and Theoretical Chemistry, Molecular Biology, 030304 developmental biology, Cathepsin, Organic Chemistry, lung inflammation, Active site, Cathepsins, Enzyme, lcsh:Biology (General), lcsh:QD1-999, biology.protein, Oxidative stress, Cysteine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a60663dd4834805100a015cfca60f8
https://www.mdpi.com/1422-0067/21/6/1944

المؤلفون: Thomas Baranek, Agnès Petit-Courty, Andrea C. Schamberger, Fabien Lecaille, Ahlame Saidi, Pierre-Marie Andrault, Oliver Eickelberg, Thibault Chazeirat, Damien Sizaret, Mylène Wartenberg, Serge Guyétant, Elisabeth Hennen, Gilles Lalmanach, Justine Renault, Yves Courty, Claudia A. Staab-Weijnitz

المساهمون: Université de Tours (UT), Centre d’Etude des Pathologies Respiratoires (CEPR), UMR 1100 (CEPR), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Ludwig-Maximilians-Universität München (LMU), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), brea, deborah, Centre d'Etude des Pathologies Respiratoires (CEPR), UMR 1100. Equipe 2 'Mécanismes Protéolytiques dans l'Inflammation' (CEPR. Equipe 2), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Comprehensive Pneumology Center - Institute of Lung Biology and Disease (iLBD), German Center for Lung Research, Anatomie et cytologie pathologique [Tours], Infectiologie et Santé Publique (UMR ISP), Institut National de la Recherche Agronomique (INRA)-Université de Tours (UT), INSERM, Université de Tours, Région Centre-Val de Loire (project BPCO-LYSE no. 2015103986), Deutsche Forschungsgemeinschaft (DFG) within the Research Training Group DFG GRK2338, Helmholtz Zentrum München = German Research Center for Environmental Health, Lalmanach, Gilles, Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Recherche Agronomique (INRA)-Université de Tours, Gonzalez, Loïc

المصدر: American Journal of Physiology-Lung Cellular and Molecular Physiology
American Journal of Physiology-Lung Cellular and Molecular Physiology, American Physiological Society, 2019, 317 (5), pp.L625-L638. ⟨10.1152/ajplung.00061.2019⟩
Am. J. Physiol. Lung Cell Mol. Physiol. 317, L625-L638 (2019)

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Male, Physiology, oxidation, medicine.medical_treatment, [SDV]Life Sciences [q-bio], Respiratory Mucosa, smokers, medicine.disease_cause, Cigarette Smoking, 03 medical and health sciences, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Cigarette smoking, Physiology (medical), Cigarette smoke, Medicine, Humans, COPD, cysteine protease, Cigarette Smoke, Copd, Cysteine Protease, Oxidation, Smokers, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], [SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], Cells, Cultured, Cathepsin S, Aged, Protease, business.industry, cigarette smoke, Epithelial Cells, Cell Biology, Middle Aged, medicine.disease, Cysteine protease, Cathepsins, 3. Good health, respiratory tract diseases, [SDV] Life Sciences [q-bio], Oxidative Stress, 030104 developmental biology, 030228 respiratory system, Case-Control Studies, Immunology, Female, business, Lung tissue, Oxidative stress

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ccbff970691c72a8be55cbc9f06d21
https://hal.archives-ouvertes.fr/hal-03604585

المؤلفون: Mylène Wartenberg, Ahlame Saidi, Mathieu Galibert, Vincent Aucagne, Alix Joulin-Giet, Gilles Lalmanach, Christopher J. Scott, Julien Burlaud-Gaillard, Agnès F. Delmas, Fabien Lecaille

المساهمون: Pathologies Respiratoires : Protéolyse et Aérosolthérapie, Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM), Queen's University [Belfast] (QUB), Centre de biophysique moléculaire (CBM), Université d'Orléans (UO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Lalmanach, Gilles, Centre d’Etude des Pathologies Respiratoires (CEPR), UMR 1100 (CEPR), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université d'Orléans (UO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Plateforme IBISA de Microscopie Electronique [CHRU de Tours] (UNIV Tours), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)-Université de Tours (UT)

المصدر: Biochimie
Biochimie, Elsevier, 2019, ⟨10.1016/j.biochi.2019.03.013⟩
Biochimie, 2019, 166, pp.84-93. ⟨10.1016/j.biochi.2019.03.013⟩

مصطلحات موضوعية: 0301 basic medicine, THP-1 Cells, Macrophage, [SDV]Life Sciences [q-bio], Peptide, Near-infrared fluorescence (NIRF), 7. Clean energy, Biochemistry, Substrate Specificity, Cysteine cathepsin, Mice, 03 medical and health sciences, Fluorescence Resonance Energy Transfer, Extracellular, Animals, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Enzyme kinetics, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], [SDV.BBM.BC] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], Fluorescent Dyes, Cathepsin S, chemistry.chemical_classification, Spectroscopy, Near-Infrared, CATS, 030102 biochemistry & molecular biology, biology, Chemistry, Macrophages, General Medicine, Förster resonance energy transfer (FRET), Probe, Cathepsins, Fluorescence, Molecular Imaging, Protease, 030104 developmental biology, Förster resonance energy transfer, Neutrophil elastase, biology.protein, Biophysics, Oligopeptides, Spleen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c30922a20f92e3d2404edaef0e51b62
https://hal.archives-ouvertes.fr/hal-02088627

المؤلفون: Gilles Lalmanach, Andrea C. Schamberger, Thibault Chazeirat, Serge Guyétant, Damien Sizaret, Oliver Eickelberg, Justine Renault, Mylène Wartenberg, Yves Courty, Pierre-Marie Andrault, Ahlame Saidi, Agnès Petit, Fabien Lecaille

المصدر: Airway Cell Biology and Immunopathology.

مصطلحات موضوعية: COPD, Lung, CATS, business.industry, Inflammation, respiratory system, Airway obstruction, medicine.disease, medicine.disease_cause, respiratory tract diseases, medicine.anatomical_structure, Immunology, medicine, Immunohistochemistry, medicine.symptom, business, Oxidative stress, Cathepsin S

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0f7f43333076b40d33f58d6d5cc8809a
https://doi.org/10.1183/13993003.congress-2018.pa4272

المؤلفون: Fabien Lecaille, Gilles Lalmanach, Lydie Nadal-Desbarats, Mylène Wartenberg, Ahlame Saidi, Pierre-Marie Andrault

المصدر: Mechanisms of Lung Injury and Repair.

مصطلحات موضوعية: chemistry.chemical_classification, CATS, business.industry, Acrolein, Oxidative phosphorylation, Sulfinic acid, chemistry.chemical_compound, chemistry, Biochemistry, Medicine, Sulfenic acid, business, Peroxynitrite, Cysteine, Cathepsin S

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5d1c66888df529cbb52245558f4187ef
https://doi.org/10.1183/13993003.congress-2018.pa4312

المؤلفون: Fabien Lecaille, Brice Korkmaz, Alix Joulin-Giet, Sylvie Mavel, Mylène Wartenberg, Dieter Brömme, Agnès F. Delmas, Ahlame Saidi, Vincent Aucagne, Gilles Lalmanach, Matthieu Galibert

المساهمون: Centre de biophysique moléculaire (CBM), Université d'Orléans (UO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Centre d'Etude des Pathologies Respiratoires (CEPR), UMR 1100. Equipe 2 'Mécanismes Protéolytiques dans l'Inflammation' (CEPR. Equipe 2), Centre d’Etude des Pathologies Respiratoires (CEPR), UMR 1100 (CEPR), Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM), Imagerie et cerveau (iBrain - Inserm U1253 - UNIV Tours ), Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of Oral Biological and Medical Science, University of British Columbia (UBC), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2018, 144, pp.201-210. ⟨10.1016/j.ejmech.2017.12.012⟩

مصطلحات موضوعية: 0301 basic medicine, Proteases, Peptidomimetic, medicine.medical_treatment, [SDV]Life Sciences [q-bio], Cathepsin K, Pharmacology, 01 natural sciences, Substrate Specificity, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, medicine, Structure–activity relationship, Animals, Humans, Protease Inhibitors, Amino Acid Sequence, Cathepsin, Semicarbazide, Protease, 010405 organic chemistry, Organic Chemistry, General Medicine, Triazoles, Cathepsins, Protease inhibitor (biology), 3. Good health, 0104 chemical sciences, Mice, Inbred C57BL, Molecular Docking Simulation, 030104 developmental biology, chemistry, Peptidomimetics, Peptides, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171ca37c9797298d5213f24fc37790a2
https://pubmed.ncbi.nlm.nih.gov/29272750