المؤلفون: Cheng D; Department of Chinese Medicine, The University of Hong Kong-Shenzhen Hospital (HKU-SZH), Shenzhen, China.; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Lei ZG; Department of Neuroscience, City University of Hong Kong, Hong Kong, China., Chu K; Department of Psychology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Lam OJH; School of Biomedical Sciences, Faculty of Science, The University of Hong Kong, Hong Kong, China., Chiang CY; Digital Centre of State Key Laboratory of Quality Research in Chinese Medicine, Macau, China., Zhang ZJ; Department of Chinese Medicine, The University of Hong Kong-Shenzhen Hospital (HKU-SZH), Shenzhen, China. zhangzj@hku.hk.; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China. zhangzj@hku.hk.

المصدر: Alzheimer's research & therapy [Alzheimers Res Ther] 2024 May 01; Vol. 16 (1), pp. 95. Date of Electronic Publication: 2024 May 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, sigma*/metabolism , Receptors, sigma*/agonists , Sigma-1 Receptor* , Alzheimer Disease*/metabolism , Alzheimer Disease*/drug therapy , Alzheimer Disease*/pathology , Endoplasmic Reticulum*/drug effects , Endoplasmic Reticulum*/metabolism , Mice, Transgenic* , Mitochondria*/drug effects , Mitochondria*/metabolism , Hallucinogens*/pharmacology , N,N-Dimethyltryptamine*/pharmacology, Animals ; Mice ; Neurons/drug effects ; Neurons/metabolism ; Male

المؤلفون: White E; Biomedicine Discovery Institute, Department of Physiology, Monash University, Melbourne, VIC, Australia., Kennedy T; The University of Queensland, Brisbane, QLD, Australia., Ruffell S; Psychae Institue, Melbourne, VIC, Australia.; Onaya Science, Iquitos, Peru., Perkins D; Psychae Institue, Melbourne, VIC, Australia.; School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia.; School of Social and Political Science, University of Melbourne, Melbourne, VIC, Australia.; Centre for Mental Health, Swinburne University of Technology, Melbourne, VIC, Australia., Sarris J; Psychae Institue, Melbourne, VIC, Australia.; Centre for Mental Health, Swinburne University of Technology, Melbourne, VIC, Australia.; NICM Health Research Institute, Western Sydney University, Westmead, NSW, Australia.; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia.

المصدر: International journal of toxicology [Int J Toxicol] 2024 May-Jun; Vol. 43 (3), pp. 327-339. Date of Electronic Publication: 2024 Feb 16.

نوع المنشور: Journal Article; Systematic Review; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Sage Publications Country of Publication: United States NLM ID: 9708436 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1092-874X (Electronic) Linking ISSN: 10915818 NLM ISO Abbreviation: Int J Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Banisteriopsis*/chemistry , N,N-Dimethyltryptamine*/toxicity, Humans ; Animals ; Plant Extracts/toxicity ; Harmine/analogs & derivatives ; Harmine/toxicity ; Harmaline/toxicity

المؤلفون: Witowski CG; Psilera Inc., 3802 Spectrum Blvd., Suite 136B, Tampa, FL 33612, United States., Hess MR; University of Wisconsin-Madison, School of Pharmacy, 777 Highland Ave., Madison, WI 53705, United States., Jones NT; University of Wisconsin-Madison, School of Pharmacy, 777 Highland Ave., Madison, WI 53705, United States., Pellitteri Hahn MC; University of Wisconsin-Madison, School of Pharmacy, 777 Highland Ave., Madison, WI 53705, United States., Razidlo J; University of Wisconsin-Madison, School of Pharmacy, 777 Highland Ave., Madison, WI 53705, United States., Bhavsar R; University of Wisconsin-Madison, School of Pharmacy, 777 Highland Ave., Madison, WI 53705, United States., Beer C; University of Wisconsin-Madison, School of Pharmacy, 777 Highland Ave., Madison, WI 53705, United States., Gonzalez-Velazquez N; University of Wisconsin-Madison, School of Pharmacy, 777 Highland Ave., Madison, WI 53705, United States., Scarlett CO; University of Wisconsin-Madison, School of Pharmacy, 777 Highland Ave., Madison, WI 53705, United States., Wenthur CJ; University of Wisconsin-Madison, School of Pharmacy, 777 Highland Ave., Madison, WI 53705, United States; Transdisciplinary Center for Research in Psychoactive Substances, 777 Highland Ave., Madison, WI 53705, United States. Electronic address: wenthur@wisc.edu., von Salm JL; Psilera Inc., 3802 Spectrum Blvd., Suite 136B, Tampa, FL 33612, United States. Electronic address: jsalm@psilera.com.

المصدر: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2024 Aug 01; Vol. 199, pp. 106803. Date of Electronic Publication: 2024 May 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9317982 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0720 (Electronic) Linking ISSN: 09280987 NLM ISO Abbreviation: Eur J Pharm Sci Subsets: MEDLINE

مواضيع طبية MeSH: Hallucinogens*/administration & dosage , Hallucinogens*/pharmacokinetics , Delayed-Action Preparations*/administration & dosage , Delayed-Action Preparations*/pharmacokinetics , Administration, Cutaneous* , N,N-Dimethyltryptamine*/administration & dosage , N,N-Dimethyltryptamine*/pharmacokinetics, Animals ; Male ; Female ; Mice ; Transdermal Patch ; Skin Absorption/drug effects ; Brain/metabolism ; Brain/drug effects ; Behavior, Animal/drug effects

المؤلفون: Falchi-Carvalho M; Biomind Labs, Brookfield Place, 181 Bay Street, Suite 1800, Toronto, ON M5J 2T9, Canada; Department of Clinical Medicine, Health Science Center, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Wießner I; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Silva SRB; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., O Maia L; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Barros H; Graduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Laborde S; Graduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Arichelle F; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Tullman S; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Silva-Costa N; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Assunção A; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Almeida R; Department of Physiology and Behavior, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Pantrigo ÉJ; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Bolcont R; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Costa-Macedo JV; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Arcoverde E; University Hospital Onofre Lopes, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Galvão-Coelho N; Department of Physiology and Behavior, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Araujo DB; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil; Graduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil. Electronic address: draulio@neuro.ufrn.br., Palhano-Fontes F; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil. Electronic address: fernandapalhano@neuro.ufrn.br.

المصدر: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology [Eur Neuropsychopharmacol] 2024 Mar; Vol. 80, pp. 27-35. Date of Electronic Publication: 2023 Dec 22.

نوع المنشور: Clinical Trial, Phase I; Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9111390 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7862 (Electronic) Linking ISSN: 0924977X NLM ISO Abbreviation: Eur Neuropsychopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: N,N-Dimethyltryptamine*/adverse effects , N,N-Dimethyltryptamine*/metabolism , Hallucinogens*/pharmacology, Humans ; Lysergic Acid Diethylamide/pharmacology ; Psilocybin ; Blood Pressure

المؤلفون: Timmermann C; Centre for Psychedelic Research, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK. c.timmermann-slater15@imperial.ac.uk., Zeifman RJ; Centre for Psychedelic Research, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK.; NYU Langone Center for Psychedelic Medicine, NYU Grosssman School of Medicine, New York, USA., Erritzoe D; Centre for Psychedelic Research, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK., Nutt DJ; Centre for Psychedelic Research, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK.; Centre for Psychiatry, Division of Brain Sciences, Faculty of Medicine, Imperial College, London, UK., Carhart-Harris RL; Centre for Psychedelic Research, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK.; Psychedelics Division, Neuroscape, Department of Neurology, University of California, San Francisco, USA.

المصدر: Scientific reports [Sci Rep] 2024 Feb 07; Vol. 14 (1), pp. 3097. Date of Electronic Publication: 2024 Feb 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: N,N-Dimethyltryptamine* , Hallucinogens*/pharmacology, Humans ; Psilocybin ; Healthy Volunteers ; Prospective Studies ; Outcome Assessment, Health Care

المؤلفون: Eckernäs E; Unit for Pharmacokinetics and Drug Metabolism, Department of Pharmacology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden., Macan-Schönleben A; Toxicological Centre, University of Antwerp, Wilrijk, Belgium., Andresen-Bergström M; Laboratory of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden.; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Birgersson S; Unit for Pharmacokinetics and Drug Metabolism, Department of Pharmacology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden., Hoffmann KJ; Unit for Pharmacokinetics and Drug Metabolism, Department of Pharmacology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden., Ashton M; Unit for Pharmacokinetics and Drug Metabolism, Department of Pharmacology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

المصدر: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2023 Dec; Vol. 53 (8-9), pp. 515-522. Date of Electronic Publication: 2023 Nov 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE

مواضيع طبية MeSH: Cytochrome P-450 CYP2D6*/metabolism , N,N-Dimethyltryptamine*/metabolism, Humans ; Monoamine Oxidase/metabolism ; Cytochromes/metabolism ; Microsomes, Liver/metabolism

المؤلفون: Coutinho LP; Departamento de Química Analítica e Físico-Química, Centro de Ciências, Universidade Federal do Ceará, 60021-970, Fortaleza, CE, Brazil., Silva SRB; Instituto do Cérebro, Universidade Federal do Rio Grande do Norte, 59078-900, Natal, RN, Brazil., de Lima-Neto P; Departamento de Química Analítica e Físico-Química, Centro de Ciências, Universidade Federal do Ceará, 60021-970, Fortaleza, CE, Brazil., Monteiro NKV; Departamento de Química Analítica e Físico-Química, Centro de Ciências, Universidade Federal do Ceará, 60021-970, Fortaleza, CE, Brazil. Electronic address: norbertokv@ufc.br.

المصدر: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Oct 20; Vol. 678, pp. 148-157. Date of Electronic Publication: 2023 Aug 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

مواضيع طبية MeSH: N,N-Dimethyltryptamine* , Tryptophan*, Humans ; Animals ; Tryptamines ; Amino Acids

المؤلفون: Vogt SB; Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Ley L; Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Erne L; Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Straumann I; Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Becker AM; Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Klaiber A; Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Holze F; Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Vandersmissen A; Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Mueller L; Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Duthaler U; Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Rudin D; Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Luethi D; Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Varghese N; Psychiatric University Hospital, University of Basel, Basel, Switzerland.; Transfaculty Research Platform Molecular and Cognitive Neuroscience, University of Basel, Basel, Switzerland., Eckert A; Psychiatric University Hospital, University of Basel, Basel, Switzerland.; Transfaculty Research Platform Molecular and Cognitive Neuroscience, University of Basel, Basel, Switzerland., Liechti ME; Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland. matthias.liechti@usb.ch.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland. matthias.liechti@usb.ch.

المصدر: Translational psychiatry [Transl Psychiatry] 2023 May 23; Vol. 13 (1), pp. 172. Date of Electronic Publication: 2023 May 23.

نوع المنشور: Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE

مواضيع طبية MeSH: N,N-Dimethyltryptamine* , Hallucinogens*, Humans ; Healthy Volunteers ; Administration, Intravenous ; Anxiety

المؤلفون: Good M; Small Pharma, 6-8 Bonhill Street, London, EC2A 4BX, UK. meghan.good@smallpharma.co.uk., Joel Z; Small Pharma, 6-8 Bonhill Street, London, EC2A 4BX, UK., Benway T; Small Pharma, 6-8 Bonhill Street, London, EC2A 4BX, UK., Routledge C; Small Pharma, 6-8 Bonhill Street, London, EC2A 4BX, UK., Timmermann C; Department of Brain Sciences, The Centre for Psychedelic Research, Faculty of Medicine, Imperial College London, London, UK., Erritzoe D; Department of Brain Sciences, The Centre for Psychedelic Research, Faculty of Medicine, Imperial College London, London, UK., Weaver R; Sygnature Discovery, Nottingham, UK., Allen G; AllenPK, Grantham, UK., Hughes C; Hammersmith Medicines Research (HMR), London, UK., Topping H; Hammersmith Medicines Research (HMR), London, UK., Bowman A; Pharmaron UK Ltd., Rushden, UK., James E; Small Pharma, 6-8 Bonhill Street, London, EC2A 4BX, UK.

المصدر: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2023 May; Vol. 48 (3), pp. 311-327. Date of Electronic Publication: 2023 Apr 22.

نوع المنشور: Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article

بيانات الدورية: Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2107-0180 (Electronic) Linking ISSN: 03787966 NLM ISO Abbreviation: Eur J Drug Metab Pharmacokinet Subsets: MEDLINE

مواضيع طبية MeSH: N,N-Dimethyltryptamine* , Depressive Disorder, Major*/drug therapy, Adult ; Humans ; Cytochrome P-450 CYP2D6/metabolism ; Monoamine Oxidase/metabolism ; Kinetics ; Double-Blind Method ; Dose-Response Relationship, Drug

المؤلفون: Hess EM; Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA., Gould TD; Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, USA.; Baltimore Veterans Affairs Medical Center, Veterans Affairs Maryland Health Care System, Baltimore, MD, USA.

المصدر: Science (New York, N.Y.) [Science] 2023 Feb 17; Vol. 379 (6633), pp. 642-643. Date of Electronic Publication: 2023 Feb 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Hallucinogens*/pharmacology , Hallucinogens*/therapeutic use , N,N-Dimethyltryptamine*/pharmacology , N,N-Dimethyltryptamine*/therapeutic use , Receptor, Serotonin, 5-HT2A*/metabolism , Serotonin*/metabolism , Serotonin*/pharmacology , Serotonin 5-HT2 Receptor Agonists*/pharmacology , Serotonin 5-HT2 Receptor Agonists*/therapeutic use , Depression*/drug therapy, Humans ; Animals