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1
المؤلفون: Frank J. Dekker, Rob M. J. Liskamp, N. J. de Mol
المساهمون: Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Medicinal Chemistry and Bioanalysis (MCB)
المصدر: Journal of Peptide Science, 16(7), 322-328
مصطلحات موضوعية: Peptidomimetic, Stereochemistry, Entropy, Enthalpy, SIGNAL-TRANSDUCTION, Peptide, Protein Engineering, Biochemistry, src Homology Domains, Peptoids, symbols.namesake, chemistry.chemical_compound, DESIGN, Structural Biology, Amide, CRYSTAL-STRUCTURES, Surface plasmon resonance, Phosphotyrosine, Molecular Biology, Pharmacology, chemistry.chemical_classification, Binding Sites, COMPLEX, P56(LCK), Hydrogen bond, Chemistry, Organic Chemistry, Peptoid, General Medicine, N-alkylation, hydrogen bonding, Gibbs free energy, van't Hoff analysis, protein-ligand interaction, DRUG DISCOVERY, Lymphocyte Specific Protein Tyrosine Kinase p56(lck), Drug Design, peptidomimetics, symbols, SOLID-PHASE, Thermodynamics, Molecular Medicine, LIGANDS, INHIBITORS, surface plasmon resonance (SPR), Protein Binding, SRC
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المؤلفون: Marcel J.E. Fischer, N. J. de Mol
المصدر: Inflammation Research. 48:569-574
مصطلحات موضوعية: Erythrocytes, Thapsigargin, Lipid Bilayers, Immunology, Inositol 1,4,5-Trisphosphate, Receptors, Fc, In Vitro Techniques, Pharmacology, Hemolysis, Exocytosis, Cell Line, chemistry.chemical_compound, medicine, Animals, Inositol, Mast Cells, Oxazoles, Calcium signaling, Arachidonic Acid, Voltage-dependent calcium channel, Receptors, IgE, Chemistry, Receptors, Purinergic P1, beta-N-Acetylhexosaminidases, Fibronectins, Rats, Mechanism of action, Antiallergic agent, Liposomes, Histamine H1 Antagonists, Biophysics, Cattle, Indicators and Reagents, Calcium Channels, Inflammation Mediators, medicine.symptom, Intracellular
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المؤلفون: Jeannette J.C. Paulussen, Lambert H.M. Janssen, Marcel J.E. Fischer, N. J. de Mol, V. C. Van Der Heijden, R. L. Roozendaal, P. Van Dijken
المصدر: Biochemical Pharmacology. 56:693-701
مصطلحات موضوعية: Hyperphosphorylation, Inositol 1,4,5-Trisphosphate, Biology, Biochemistry, Exocytosis, Piperazines, Anti-Allergic Agents, Cell Adhesion, Tumor Cells, Cultured, medicine, Animals, Enzyme Inhibitors, Phosphorylation, Tyrosine, Inositol phosphate, Pharmacology, chemistry.chemical_classification, Receptors, IgE, Calcium Radioisotopes, Mast cell, Fibronectins, Neoplasm Proteins, Rats, Cell biology, medicine.anatomical_structure, Leukemia, Basophilic, Acute, chemistry, Cell culture, Thapsigargin, Calcium, Oxatomide, Signal transduction, Extracellular Space, Signal Transduction, medicine.drug
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المؤلفون: R. L. Roozendaal, Jeannette J.C. Paulussen, Marcel J.E. Fischer, N. J. de Mol, Lambert H.M. Janssen, R. C. Tiemessen
المصدر: Inflammation Research. 45:564-573
مصطلحات موضوعية: Intracellular Fluid, Immunology, Biology, Exocytosis, chemistry.chemical_compound, Anti-Allergic Agents, Tumor Cells, Cultured, medicine, Animals, Phosphorylation, Phosphotyrosine, Pharmacology, Receptors, IgE, Erythrocyte Membrane, Tyrosine phosphorylation, Haemolysis, Rats, Cell biology, Leukemia, Basophilic, Acute, Mechanism of action, chemistry, Thapsigargin, Calcium, Calcium Channels, medicine.symptom, Signal transduction, Extracellular Space, Cell activation, Histamine, Signal Transduction
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المؤلفون: N. J. de Mol, Lambert H.M. Janssen, Willem Verboom, David N. Reinhoudt, Klaas J. Lusthof, W. Richter
المساهمون: Faculty of Science and Technology, Molecular Nanofabrication
المصدر: Archives of biochemistry and biophysics, 277(1), 137-142. Academic Press Inc.
مصطلحات موضوعية: Xanthine Oxidase, Semiquinone, Aziridines, Biophysics, chemistry.chemical_element, Antineoplastic Agents, Cytochrome c Group, Photochemistry, Biochemistry, Oxygen, Redox, Superoxide dismutase, Structure-Activity Relationship, chemistry.chemical_compound, Cyclohexenes, Benzoquinones, Xanthine oxidase, Molecular Biology, Biotransformation, biology, Superoxide Dismutase, Superoxide, Cytochrome c, IR-72902, Catalase, Quinone, Kinetics, chemistry, biology.protein, Oxidation-Reduction
وصف الملف: application/pdf
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المؤلفون: Marcel J.E. Fischer, N. J. de Mol, R. C. Tiemessen, J. A. E. Kok-Van Esterik, Lambert H.M. Janssen, Jeannette J.C. Paulussen
المصدر: European journal of pharmacology. 312(1)
مصطلحات موضوعية: Thapsigargin, Inositol 1,4,5-Trisphosphate, Biology, Exocytosis, Piperazines, chemistry.chemical_compound, Anti-Allergic Agents, medicine, Tumor Cells, Cultured, Animals, Mast Cells, Phosphorylation, Calcimycin, Pharmacology, Tyrosine phosphorylation, Mast cell, Rats, medicine.anatomical_structure, Biochemistry, chemistry, Biophysics, Tyrosine, Calcium, Oxatomide, Signal transduction, Intracellular, medicine.drug, Signal Transduction
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المؤلفون: M, Maliepaard, S E, Groot, N J, de Mol, L H, Janssen, M, Freriks, W, Verboom, D N, Reinhoudt, M, Stephens, I J, Stratford
المصدر: Anti-cancer drug design. 11(5)
مصطلحات موضوعية: Male, Xanthine Oxidase, Cell Survival, Circular Dichroism, Antineoplastic Agents, Stereoisomerism, DNA, Cell Line, Mitomycins, Rats, Structure-Activity Relationship, Cricetulus, Cross-Linking Reagents, Liver, Cricetinae, Rhabdomyosarcoma, Tumor Cells, Cultured, Animals, Humans, Rats, Wistar, Oxidation-Reduction, Dihydrolipoamide Dehydrogenase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::03733ab8b79ec223845a57f28a6b05fc
https://pubmed.ncbi.nlm.nih.gov/8765532 -
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المؤلفون: J J, Paulussen, M J, Fischer, E P, Roelofsen, D A, Horbach, N J, de Mol, L H, Janssen
المصدر: Arzneimittel-Forschung. 46(5)
مصطلحات موضوعية: Arachidonic Acid, Ionophores, L-Lactate Dehydrogenase, Histamine Release, Exocytosis, Piperazines, beta-N-Acetylhexosaminidases, Rats, Structure-Activity Relationship, Anti-Allergic Agents, Histamine H1 Antagonists, Animals, Tetradecanoylphorbol Acetate, Mast Cells, Calcimycin, Cells, Cultured, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::aa7ee3e7cf56129879109c75a601846e
https://pubmed.ncbi.nlm.nih.gov/8737634 -
9Indoloquinone EO9: DNA interstrand cross-linking upon reduction by DT-diaphorase or xanthine oxidase
المؤلفون: S. E. Groot, A. Wolfs, Lambert H.M. Janssen, N. J. De Mol, Marc Maliepaard
المصدر: British Journal of Cancer
مصطلحات موضوعية: Male, Cancer Research, Dicumarol, Xanthine Oxidase, Indoles, Mitomycin, Aziridines, Antineoplastic Agents, chemistry.chemical_compound, medicine, NAD(P)H Dehydrogenase (Quinone), Animals, Indolequinones, Rats, Wistar, Xanthine oxidase, Biotransformation, chemistry.chemical_classification, Biological activity, DNA, Dicoumarol, Xanthine, Rats, Enzyme, Cross-Linking Reagents, Oncology, Biochemistry, Mechanism of action, chemistry, Liver, medicine.symptom, Oxidation-Reduction, medicine.drug, Research Article
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57207256bc21a437924b65f977e76158
https://pubmed.ncbi.nlm.nih.gov/7536024 -
10
المؤلفون: E. P. W. Roelofsen, D. A. Horbach, Jeannette J.C. Paulussen, J.C. van Miltenburg, Marcel J.E. Fischer, N. J. de Mol, Lambert H.M. Janssen
المصدر: Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 44(2)
مصطلحات موضوعية: 1,2-Dipalmitoylphosphatidylcholine, Immunology, Ionophore, Phospholipid, chemistry.chemical_element, Calcium, Exocytosis, Piperazines, chemistry.chemical_compound, Meclizine, Structure-Activity Relationship, medicine, Tumor Cells, Cultured, Animals, Mast Cells, Antigens, Pharmacology, Liposome, Calorimetry, Differential Scanning, Receptors, IgE, Cell Membrane, Astemizole, Cetirizine, beta-N-Acetylhexosaminidases, Rats, Membrane, chemistry, Biochemistry, Leukemia, Basophilic, Acute, Hydroxyzine, Lipophilicity, Histamine H1 Antagonists, Tetradecanoylphorbol Acetate, Oxatomide, medicine.drug, Signal Transduction