المؤلفون: Ruobing Qi, Wenhua Yang, Sixian Zhu, Jie Mao, Bei Yang, Anhui Xu, Qiang Fu

المصدر: Frontiers in Oncology, Vol 14 (2024)

مصطلحات موضوعية: NET G2, HCC, camrelizumab (SHR1210), apatinib, PD-1, TACE, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1278340/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/f44f77e8dbfa4d06861987a799d7d8e8

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

المؤلفون: Peerawitch Petchmak, Punnawat Chandrachamnong

مصطلحات موضوعية: appendicitis, NET G2, carcinoid tumors, appendix, appendiceal neuroendocrine tumors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::75d08b8bc4ef5adcd288aecedeb137a5

المؤلفون: Giorgia Marchesini, Claudio Zardini, Giuseppe Zamboni, Corrado Rubini, Massimo Falconi, Paola Castelli, Stefano Partelli, Stefano Crippa, Ilaria Pergolini

المساهمون: Crippa, Stefano, Pergolini, Ilaria, Rubini, Corrado, Castelli, Paola, Partelli, Stefano, Zardini, Claudio, Marchesini, Giorgia, Zamboni, Giuseppe, Falconi, Massimo

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, endocrine system diseases, medicine.medical_treatment, Medical Overuse, 030230 surgery, Diagnosis, Differential, Background Segmental/diffuse dilatation of the main pancreatic duct (MPD) is the typical feature of combined/main-duct intraductal papillary mucinous neoplasms (CMD-IPMNs). MPD dilation in IPMNs may be also expression of mucus hypersecretion/obstructive chronic pancreatitis (OCP). The aim of this study was to evaluate the presence and extension of MPD involvement by tumor/OCP and assess the risk of overtreatment. Methods Retrospective analysis of suspected CMD-IPMNs resected between January 2009 and October 2014 were included. Pathologic correlations among MPD dilatation, IPMN, and OCP was searched. Results Overall, 93 patients were resected for suspected CMD-IPMNs. At pathology, CMD-IPMNs were found in 69 patients (74%). Branch-duct IPMNs (BD-IPMNs) were found in 8 cases (9%), pancreatic ductal adenocarcinoma (PDAC) in absence of IPMN in 9 (10%), cystic neuroendocrine tumor (NET G2) in 1 (1%), serous cystadenoma in 2 (2%), and OCP alone/mucinous metaplasia in 4 patients (4%). Overall, 18 patients (19%) underwent an overtreatment because unnecessary (2 BD-IPMNs, 2 serous cystadenomas, and 4 OCPs only) or too extensive resections (9 CMD-IPMNs and 1 PDAC with associated OCP). In these, total pancreatectomy was the most common procedure (67%). Median size of MPD in IPMN-involved area was 12 mm compared with 7 mm when only OCP was found (P <, 03 medical and health sciences, Pancreatectomy, 0302 clinical medicine, MPD dilation, Pancreatitis, Chronic, Carcinoma, medicine, Humans, Diagnostic Errors, Pancreatitis, chronic, Aged, Retrospective Studies, Aged, 80 and over, Pancreatic duct, main pancreatic duct (MPD), mucus hypersecretion/obstructive chronic pancreatitis (OCP), business.industry, main pancreatic duct (MPD),combined/main-duct intraductal papillary mucinous neoplasms (CMD-IPMNs), MPD dilation, mucus hypersecretion/obstructive chronic pancreatitis (OCP), Pancreatic Ducts, Middle Aged, medicine.disease, Serous Cystadenoma, Surgery, Pancreatic Neoplasms, Partial Pancreatectomy, medicine.anatomical_structure, 05). Conclusion There is a considerable risk of overtreatment in patients with a preoperative morphologic diagnosis of CMD-IPMNs. Partial pancreatectomy with margin examination should be performed instead of upfront total pancreatectomy. Radiologic observation can be considered in asymptomatic patients with "worrisome" MPD dilatation (5-9 mm) and lacking other high-risk stigmata, Pancreatitis, Female, 030211 gastroenterology & hepatology, combined/main-duct intraductal papillary mucinous neoplasms (CMD-IPMNs), Radiology, Differential diagnosis, business, Carcinoma, Pancreatic Ductal, Dilatation, Pathologic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6406d422afc66adc79f674cbde14993
http://hdl.handle.net/11562/935228

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.