المؤلفون: Mehmet Gul, Esra Ayan, Ebru Destan, J. Austin Johnson, Alaleh Shafiei, Abdullah Kepceoğlu, Merve Yilmaz, Fatma Betül Ertem, İlkin Yapici, Bilge Tosun, Nilüfer Baldir, Nurettin Tokay, Zeliş Nergiz, Gözde Karakadioğlu, Seyide Seda Paydos, Cahine Kulakman, Cengiz Kaan Ferah, Ömür Güven, Necati Atalay, Enver Kamil Akcan, Haluk Cetinok, Nazlı Eylül Arslan, Kardelen Şabanoğlu, Bengisu Aşci, Serra Tavli, Helin Gümüsboğa, Sevde Altuntaş, Masami Otsuka, Mikako Fujita, Şaban Teki̇n, Halilibrahim Çi̇ftçi̇, Serdar Durdaği, Ezgi Karaca, Burcu Kaplan Türköz, Burak Veli Kabasakal, Ahmet Kati, Hasan DeMi̇rci̇

المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/f18f8cb3aa204e4c80e833bbd23b31ce

المؤلفون: Omur Guven, Mehmet Gul, Esra Ayan, J Austin Johnson, Baris Cakilkaya, Gozde Usta, Fatma Betul Ertem, Nurettin Tokay, Busra Yuksel, Oktay Gocenler, Cengizhan Buyukdag, Sabine Botha, Gihan Ketawala, Zhen Su, Brandon Hayes, Frederic Poitevin, Alexander Batyuk, Chun Hong Yoon, Christopher Kupitz, Serdar Durdagi, Raymond G. Sierra, Hasan DeMirci

المصدر: Crystals, Vol 11, Iss 12, p 1579 (2021)

مصطلحات موضوعية: SARS-CoV-2, main protease, serial femtosecond crystallography, high-throughput drug screening, Crystallography, QD901-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4352/11/12/1579; https://doaj.org/toc/2073-4352

URL الوصول: https://doaj.org/article/304b6058372a49cd8edb08044f9a1e25

المؤلفون: NECATİ ATALAY, ENVER KAMİL AKCAN, MEHMET GÜL, ESRA AYAN, EBRU DESTAN, FATMA BETÜL ERTEM KUZUCU, NURETTİN TOKAY, BARIŞ ÇAKILKAYA, ZELİŞ NERGİZ, GÖZDE KARAKADIOĞLU USTA, ABDULLAH KEPCEOĞLU, İLKİN YAPICI, BİLGE TOSUN, NİLÜFER BALDIR, GÜNSELİ YILDIRIM, J AUSTIN JOHNSON, ÖMÜR GÜVEN, ALALEH SHAFIEI, NAZLI EYLÜL ARSLAN, MERVE YILMAZ, CAHİNE KULAKMAN, SEYİDE SEDA PAYDOS, SEYNEP SENA ÇİNAL, KARDELEN ŞABANOĞLU, AYŞEGÜL PAZARÇEVİREN, AYŞENUR YILMAZ, BAŞAK CANBAY, BENGİSU AŞÇI, ESRA KARTAL, SERRA TAVLI, MEHMET ÇALISEKİ, GÜNCE GÖÇ, ARİF MERMER, GAMZE YEŞİLAY, SEVDE ALTUNTAŞ, HIROSHI TATEISHI, MASAMI OTSUKA, MIKAKO FUJITA, ŞABAN TEKİN, HALİLİBRAHİM ÇİFTÇİ, SERDAR DURDAĞI, GİZEM DİNLER DOĞANAY, EZGİ KARACA, BURCU KAPLAN TÜRKÖZ, BURAK VELİ KABASAKAL, AHMET KATI, HASAN DEMİRCİ

المصدر: Turkish Journal of Biology. 47:1-13

مصطلحات موضوعية: Physiology, Genetics, Cell Biology, General Agricultural and Biological Sciences, Molecular Biology, Microbiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f9e3128c4624e7210b66fb0c70894391
https://doi.org/10.55730/1300-0152.2637

المؤلفون: Ece Erdemoglu, Nurettin Tokay, Şaban Tekin, Lalehan Oktay, Elif Acar, Hasan DeMirci, Timucin Avsar, Alpsu Olkan, Yesim Yumak, Bertan Koray Balcioglu, Muge Didem Orhan, Seyma Calis, Hasan Umit Ozturk, Sehriban Buyukkilic, Yuksel Cetin, Yasar Enes Butun, Aysenur Ozcan, Atilla Akdemir, Muge Serhatli, Şeyma Işık, Tugba Bagci-Onder, Seyma Aydinlik, Mustafa Guzel, Serdar Durdagi, Alisan Kayabolen, Ilayda Tolu

المساهمون: Kayabölen, Alişan, Önder, Tuğba Bağcı (ORCID 0000-0003-3646-2613 & YÖK ID 184359), Demirci, Hasan (ORCID 0000-0002-9135-5397 & YÖK ID 307350), Durdağı, Serdar, Avşar, Timuçin, Orhan, Müge Didem, Serhatlı, Müge, Balcıoğlu, Bertan Koray, Öztürk, Hasan Ümit, Çetin, Yüksel, Aydınlık, Şeyma, Tekin, Şaban, Güzel, Mustafa, Akdemir, Atilla, Çalış, Şeyma, Oktay, Lalehan, Tolu, İlayda, Bütün, Yaşar Enes, Erdemoğlu, Ece, Olkan, Alpsu, Tokay, Nurettin, Işık, Şeyma, Özcan, Ayşenur, Acar, Elif, Büyükkılıç, Şehriban, Yumak, Yeşim, Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM), School of Medicine, College of Sciences, Department of Molecular Biology and Genetics, AKDEMİR, ATİLLA

المصدر: Molecular Therapy

مصطلحات موضوعية: Cyclopropanes, Models, Molecular, Vitro Studies, pseudovirus neutralization, Protein Conformation, medicine.medical_treatment, Pharmacology, Acetates, Neutralization, Drug Discovery, Chlorocebus aethiops, MD simulations, Leukotriene, drug repurposing, Molecular Structure, Chemistry, Biotechnology and applied microbiology, Serine Endopeptidases, Small molecule, Molecular Docking Simulation, montelukast, virus neutralization, Quinolines, Molecular Medicine, Original Article, Angiotensin-Converting Enzyme 2, medicine.drug, Cell Survival, COVID-19, Drug repurposing, Molecular docking, Montelukast, Pseudovirus Neutralization, Virus neutralization, Sulfides, Virus, Viral entry, Neutralization Tests, Genetics, medicine, Animals, Humans, Molecular Biology, Vero Cells, Protease, SARS-CoV-2, Silico Simulations, Drug Repositioning, molecular docking, Virus Internalization, In vitro, respiratory tract diseases, HEK293 Cells, A549 Cells

وصف الملف: pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7b5bf178ea2423fe4889fd0a1d910a
https://pubmed.ncbi.nlm.nih.gov/34678509

المؤلفون: Nurettin Tokay, Pelin Balcik-Ercin, Irem Yalim-Camci, Metin Çetin, Tamer Yagci, A. Emre Sayan, Gorkem Odabas

المصدر: Molecular Carcinogenesis. 58:1068-1081

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Epithelial-Mesenchymal Transition, Biology, Proto-Oncogene Mas, Proto-Oncogene Protein c-ets-1, 03 medical and health sciences, 0302 clinical medicine, ETS1, Cell Movement, Cell Line, Tumor, Neoplasms, Humans, Epithelial–mesenchymal transition, Molecular Biology, Transcription factor, Zinc Finger E-box Binding Homeobox 2, Gene knockdown, Binding Sites, Twist-Related Protein 1, Nuclear Proteins, Promoter, Hep G2 Cells, Cell biology, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Matrix Metalloproteinase 9, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Cancer cell, Chromatin immunoprecipitation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3fd106006af6185a609b595e2cc1497
https://doi.org/10.1002/mc.22994

المؤلفون: Yesim Yumak, Ece Erdemoglu, Elif Acar, Aysenur Ozcan, Ilayda Tolu, Muge Didem Orhan, Yuksel Cetin, Alisan Kayabolen, Alpsu Olkan, Şaban Tekin, Şeyma Işık, Hasan DeMirci, Timucin Avsar, Sehriban Buyukkilic, Muge Serhatli, Tugba Bagci-Onder, Bertan Koray Balcioglu, Nurettin Tokay, Yasar Enes Butun, Serdar Durdagi, Atilla Akdemir, Lalehan Oktay, Seyma Calis, Hasan Umit Ozturk, Seyma Aydinlik, Mustafa Guzel

مصطلحات موضوعية: Leukotriene, Chemistry, In silico, medicine, Pharmacology, Favipiravir, Cytotoxicity, Small molecule, In vitro, Montelukast, Neutralization, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8788d857d84e850cdf2d2aa14fde6598
https://doi.org/10.1101/2020.12.26.424423

المؤلفون: Gozde Usta, Fatma Betul Ertem, Nurettin Tokay, Chun Hong Yoon, Raymond G. Sierra, Christopher Kupitz, Oktay Gocenler, Mehmet Gul, Busra Yuksel, Baris Cakilkaya, Frédéric Poitevin, Zhen Su, Gihan K. Ketawala, Cengizhan Buyukdag, Sabine Botha, Serdar Durdagi, Brandon Hayes, Hasan DeMirci, Omur Guven, Esra Ayan, J. Austin Johnson, Alexander Batyuk

المساهمون: Güven, Ömür, Gül, Mehmet, Ayan, Esra, Johnson, Jerome Austin, Çakılkaya, Barış, Usta, Gözde Karakadıoğlu, Ertem, Fatma Betül, Tokay, Nurettin, Yüksel, Büşra, Göcenler, Oktay, Büyükdağ, Cengizhan, Demirci, Hasan (ORCID 0000-0002-9135-5397 & YÖK ID 307350), Botha, Sabine, Ketawala, Gihan, Su, Zhen, Hayes, Brandon, Poitevin, Frederic, Batyuk, Alexander, Yoon, Chun Hong, Kupitz, Christopher, Durdağı, Serdar, Sierra, Raymond G., Koç Üniversitesi İş Bankası Enfeksiyon Hastalıkları Uygulama ve Araştırma Merkezi (EHAM) / Koç University İşbank Center for Infectious Diseases (KU-IS CID), Graduate School of Sciences and Engineering, College of Sciences, Department of Molecular Biology and Genetics, Department of Chemical and Biological Engineering

المصدر: Crystals, Vol 11, Iss 1579, p 1579 (2021)
Crystals; Volume 11; Issue 12; Pages: 1579
Crystals

مصطلحات موضوعية: Drug, serial femtosecond crystallography, Data collection, Crystallography, Coronavirus disease 2019 (COVID-19), Computer science, Drug candidate, SARS-CoV-2, media_common.quotation_subject, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), General Chemical Engineering, high-throughput drug screening, Computational biology, Condensed Matter Physics, Main protease, Serial femtosecond crystallography, High-throughput drug screening, Inorganic Chemistry, Drug repositioning, Materials science, main protease, QD901-999, Femtosecond, General Materials Science, Throughput (business), media_common

وصف الملف: application/pdf; pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12460459ee1a2eca344a500571f03022
https://doi.org/10.3390/cryst11121579

المؤلفون: Irem Yalim-Camci, Tamer Yagci, Pelin Balcik-Ercin, Nurettin Tokay, A. Emre Sayan, Metin Çetin, Gorkem Odabas

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Epithelial-Mesenchymal Transition, Blotting, Western, Human Protein Atlas, Biology, 03 medical and health sciences, Cell Line, Tumor, medicine, Humans, Gene, Zinc Finger E-box Binding Homeobox 2, Regulation of gene expression, Binding Sites, General Medicine, medicine.disease, Molecular biology, Primary tumor, Chromatin, ChIP-sequencing, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Oncology, Regulatory sequence, N-Acetylgalactosaminyltransferases, Molecular Medicine, Human genome, Genome-Wide Association Study

وصف الملف: text

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8993def7f22e96c0b622f4210fde2ca
https://aperta.ulakbim.gov.tr/record/36631