المؤلفون: Patel NR; a Nemucore Medical Innovations, Inc. , Wellesley , MA., Piroyan A; a Nemucore Medical Innovations, Inc. , Wellesley , MA., Ganta S; a Nemucore Medical Innovations, Inc. , Wellesley , MA., Morse AB; a Nemucore Medical Innovations, Inc. , Wellesley , MA., Candiloro KM; a Nemucore Medical Innovations, Inc. , Wellesley , MA., Solon AL; a Nemucore Medical Innovations, Inc. , Wellesley , MA., Nack AH; a Nemucore Medical Innovations, Inc. , Wellesley , MA., Galati CA; a Nemucore Medical Innovations, Inc. , Wellesley , MA., Bora C; a Nemucore Medical Innovations, Inc. , Wellesley , MA., Maglaty MA; b Molecular Therapeutics Program, Fox Chase Cancer Center , 333 Cottman Avenue, Philadelphia , PA., O'Brien SW; b Molecular Therapeutics Program, Fox Chase Cancer Center , 333 Cottman Avenue, Philadelphia , PA., Litwin S; b Molecular Therapeutics Program, Fox Chase Cancer Center , 333 Cottman Avenue, Philadelphia , PA.; c Biostatistics Facility, Fox Chase Cancer Center , 333 Cottman Avenue, Philadelphia , PA., Davis B; a Nemucore Medical Innovations, Inc. , Wellesley , MA., Connolly DC; b Molecular Therapeutics Program, Fox Chase Cancer Center , 333 Cottman Avenue, Philadelphia , PA., Coleman TP; a Nemucore Medical Innovations, Inc. , Wellesley , MA.

المصدر: Cancer biology & therapy [Cancer Biol Ther] 2018 Jul 03; Vol. 19 (7), pp. 554-564. Date of Electronic Publication: 2018 May 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137842 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-8576 (Electronic) Linking ISSN: 15384047 NLM ISO Abbreviation: Cancer Biol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*administration & dosage , Docetaxel/*administration & dosage , Drug Carriers/*chemistry , Folate Receptor 1/*metabolism , Ovarian Neoplasms/*drug therapy, Animals ; Antineoplastic Agents/pharmacokinetics ; Cell Line, Tumor ; Disease Models, Animal ; Docetaxel/pharmacokinetics ; Drug Carriers/pharmacology ; Emulsions ; Endocytosis ; Female ; Folic Acid/metabolism ; Gadolinium/chemistry ; Gadolinium/pharmacology ; Humans ; Magnetic Resonance Imaging/methods ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Molecular Imaging/methods ; Nanoparticles/chemistry ; Neoplasm Recurrence, Local ; Ovarian Neoplasms/diagnostic imaging ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/pathology ; Theranostic Nanomedicine/methods

المؤلفون: Patel NR; Nemucore Medical Innovations, Inc. , Worcester, Massachusetts 01608, United States., Piroyan A; Nemucore Medical Innovations, Inc. , Worcester, Massachusetts 01608, United States., Nack AH; Nemucore Medical Innovations, Inc. , Worcester, Massachusetts 01608, United States.; Blue Ocean Biomanufacturing, Inc. , Worcester, Massachusetts 01608, United States., Galati CA; Nemucore Medical Innovations, Inc. , Worcester, Massachusetts 01608, United States.; Blue Ocean Biomanufacturing, Inc. , Worcester, Massachusetts 01608, United States., McHugh M; Nemucore Medical Innovations, Inc. , Worcester, Massachusetts 01608, United States., Orosz S; Nemucore Medical Innovations, Inc. , Worcester, Massachusetts 01608, United States., Keeler AW; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States., O'Neal S; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.; Translational Oncology and Nanoparticle Drug Development Initiative (TOND2I) Lab, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.; Carolina Center of Cancer Nanotechnology Excellence, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.; University of North Carolina Lineberger Comprehensive Cancer Center , Chapel Hill, North Carolina 27514, United States., Zamboni WC; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.; Translational Oncology and Nanoparticle Drug Development Initiative (TOND2I) Lab, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.; Carolina Center of Cancer Nanotechnology Excellence, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.; Center of Pharmacogenomics and Individualized Therapy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.; University of North Carolina Lineberger Comprehensive Cancer Center , Chapel Hill, North Carolina 27514, United States., Davis B; Nemucore Medical Innovations, Inc. , Worcester, Massachusetts 01608, United States.; Blue Ocean Biomanufacturing, Inc. , Worcester, Massachusetts 01608, United States., Coleman TP; Nemucore Medical Innovations, Inc. , Worcester, Massachusetts 01608, United States.; Blue Ocean Biomanufacturing, Inc. , Worcester, Massachusetts 01608, United States.; Foundation for the Advancement of Personalized Medicine Manufacturing , Phoenix, Arizona 85013, United States.

المصدر: Molecular pharmaceutics [Mol Pharm] 2016 Jun 06; Vol. 13 (6), pp. 1996-2009. Date of Electronic Publication: 2016 May 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Emulsions/*administration & dosage , Emulsions/*chemistry , Folic Acid/*administration & dosage , Folic Acid/*chemistry , Organoplatinum Compounds/*administration & dosage , Organoplatinum Compounds/*chemistry , Ovarian Neoplasms/*drug therapy, Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Drug Carriers/chemistry ; Drug Delivery Systems/methods ; Drug Resistance, Multiple/drug effects ; Female ; Folate Receptor 1/metabolism ; Gadolinium DTPA/chemistry ; HeLa Cells ; Humans ; Mice ; Ovarian Neoplasms/metabolism ; Particle Size ; Polyethylene Glycols/chemistry ; Theranostic Nanomedicine/methods