نتائج البحث - "Nadilly Bonagas"

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دورية أكاديمية

Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/a5be37faa19d4d1fbbb9c428f096c524

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Supplementary Table S1 from Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

المؤلفون: Pål Stenmark, Thomas Helleday, Evert Homan, Yasmin Andersson, Martin Henriksson, Maria Häggblad, Sabin Llona-Minguez, Leif Dahllund, Nadilly Bonagas, Elisée Wiita, Olga Loseva, Katarina Färnegårdh, Nina M.S. Gustafsson, Ann-Sofie Jemth, Robert Gustafsson

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b582a3653a74d99a229e83fd3a02ea1e
https://doi.org/10.1158/0008-5472.22414455

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Supplementary Methods and References from Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

المؤلفون: Pål Stenmark, Thomas Helleday, Evert Homan, Yasmin Andersson, Martin Henriksson, Maria Häggblad, Sabin Llona-Minguez, Leif Dahllund, Nadilly Bonagas, Elisée Wiita, Olga Loseva, Katarina Färnegårdh, Nina M.S. Gustafsson, Ann-Sofie Jemth, Robert Gustafsson

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0bc9eb2d0df2cb71d1f9ae89c01980c
https://doi.org/10.1158/0008-5472.22414458

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Data from Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

المؤلفون: Pål Stenmark, Thomas Helleday, Evert Homan, Yasmin Andersson, Martin Henriksson, Maria Häggblad, Sabin Llona-Minguez, Leif Dahllund, Nadilly Bonagas, Elisée Wiita, Olga Loseva, Katarina Färnegårdh, Nina M.S. Gustafsson, Ann-Sofie Jemth, Robert Gustafsson

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::27b1c130815606c4da40d07eee51a98b
https://doi.org/10.1158/0008-5472.c.6508983.v1

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Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

المؤلفون: Nadilly Bonagas, Nina M. S. Gustafsson, Martin Henriksson, Petra Marttila, Robert Gustafsson, Elisée Wiita, Sanjay Borhade, Alanna C. Green, Karl S. A. Vallin, Antonio Sarno, Richard Svensson, Camilla Göktürk, Therese Pham, Ann-Sofie Jemth, Olga Loseva, Victoria Cookson, Nicole Kiweler, Lars Sandberg, Azita Rasti, Judith E. Unterlass, Martin Haraldsson, Yasmin Andersson, Emma R. Scaletti, Christoffer Bengtsson, Cynthia B. J. Paulin, Kumar Sanjiv, Eldar Abdurakhmanov, Linda Pudelko, Ben Kunz, Matthieu Desroses, Petar Iliev, Katarina Färnegårdh, Andreas Krämer, Neeraj Garg, Maurice Michel, Sara Häggblad, Malin Jarvius, Christina Kalderén, Amanda Bögedahl Jensen, Ingrid Almlöf, Stella Karsten, Si Min Zhang, Maria Häggblad, Anders Eriksson, Jianping Liu, Björn Glinghammar, Natalia Nekhotiaeva, Fredrik Klingegård, Tobias Koolmeister, Ulf Martens, Sabin Llona-Minguez, Ruth Moulson, Helena Nordström, Vendela Parrow, Leif Dahllund, Birger Sjöberg, Irene L. Vargas, Duy Duc Vo, Johan Wannberg, Stefan Knapp, Hans E. Krokan, Per I. Arvidsson, Martin Scobie, Johannes Meiser, Pål Stenmark, Ulrika Warpman Berglund, Evert J. Homan, Thomas Helleday

المصدر: Nature Cancer

مصطلحات موضوعية: Methylenetetrahydrofolate Dehydrogenase (NADP), Cancer och onkologi, Leukemia, Myeloid, Acute, Cancer Research, Oncology, Cellbiologi, Aminohydrolases, Hydrolases, Cancer and Oncology, Humans, Cell Biology, Multifunctional Enzymes, Thymidine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc803a4ce48681e11987b33fd0a94af
https://doi.org/10.1038/s43018-022-00331-y

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Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells

مصطلحات موضوعية: Cancer och onkologi, Cellbiologi, Physiology (medical), Endocrinology, Diabetes and Metabolism, Cancer and Oncology, Internal Medicine, Cell Biology, Cell and Molecular Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef4c9b031ee478e94f3df8742d2401f
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-206656

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Supplementary methods for 'Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress'

المؤلفون: Nadilly Bonagas, Nina Gustafsson, Martin Henriksson, Petra Marttila, Robert Gustafsson, Elisée Wiita, Sanjay Borhade, Alanna Green, Karl Vallin, Antonio Sarno, Richard Svensson, Camilla Göktürk, Therese Pham, Ann-Sofie Jemth, Olga Loseva, Victoria Cookson, Nicole Kiweler, Lars Sandberg, Azita Rasti, Judith Unterlass, Martin Haraldsson, Yasmin Andersson, Emma Scaletti, Christoffer Bengtsson, Cynthia Paulin, Kumar Sanjiv, Eldar Abdurakhmanov, Linda Pudelko, Ben Kunz, Matthieu Desroses, Petar Iliev, Katarina Färnegårdh, Andreas Krämer, Neeraj Garg, Maurice Michel, Sara Häggblad, Malin Jarvius, Christina Kalderén, Amanda Bögedahl Jensen, Ingrid Almlöf, Stella Karsten, Si Min Zhang, Maria Häggblad, Anders Eriksson, Jianping Liu, Björn Glinghammar, Natalia Nekhotiaeva, Fredrik Klingegård, Tobias Koolmeister, Ulf Martens, Sabin Llona-Minguez, Ruth Moulson, Helena Nordström, Vendela Parrow, Leif Dahllund, Birger Sjöberg, Irene Vargas, Duy Duc Vo, Johan Wannberg, Stefan Knapp, Hans Krokan, Per Arvidsson, Martin Scobie, Johannes Meiser, Pål Stenmark, Ulrika Warpman Berglund, Evert Homan, Thomas Helleday

مصطلحات موضوعية: hemic and lymphatic diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::032514cb5181fdda8fdfefd73848c5d0
https://doi.org/10.21203/rs.3.pex-1730/v1

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Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor

المؤلفون: Sabin Llona-Minguez, Katarina Färnegårdh, Leif Dahllund, Maria Häggblad, Nina M. S. Gustafsson, Yasmin Andersson, Pål Stenmark, Nadilly Bonagas, Ann-Sofie Jemth, Thomas Helleday, Olga Loseva, Elisee Wiita, Robert Gustafsson, Martin Henriksson, Evert Homan

المصدر: Cancer Research. 77:937-948

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3256f9ed83d8d25e89cf16c10030ce33
https://doi.org/10.1158/0008-5472.can-16-1476

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Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Cell Survival, Phosphofructokinase-2, DNA damage, DNA repair, Science, General Physics and Astronomy, Antineoplastic Agents, Radiation Tolerance, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, chemistry.chemical_compound, Cell Line, Tumor, Neoplasms, Radiation, Ionizing, Hydroxybenzoates, medicine, Humans, DNA Breaks, Double-Stranded, Sulfones, Enzyme Inhibitors, RNA, Small Interfering, lcsh:Science, chemistry.chemical_classification, Multidisciplinary, Biphenyl Compounds, Recombinational DNA Repair, Cancer, Chemoradiotherapy, General Chemistry, medicine.disease, Small molecule, 3. Good health, Cell biology, 030104 developmental biology, Enzyme, chemistry, Cancer cell, lcsh:Q, Homologous recombination, DNA, Dideoxynucleotides

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ea467c334b76d93f503c7eee3f7fb8

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