المؤلفون: Christopher T. Smith, Linh C. Dang, Leah L. Burgess, David H. Zald, Darcy K. Smith, Ronald L. Cowan, Scott F. Perkins, Nam T. Le, Gregory R. Samanez-Larkin, Robert M. Kessler, M. Danica San Juan

المصدر: Psychopharmacology. 236:581-590

مصطلحات موضوعية: Adult, Male, Fluorine Radioisotopes, medicine.medical_specialty, Dextroamphetamine, Dopamine, media_common.quotation_subject, Placebo, Article, Young Adult, 03 medical and health sciences, Sex Factors, 0302 clinical medicine, Dopamine receptor D2, Internal medicine, medicine, Humans, Young adult, Amphetamine, Menstrual cycle, Aged, media_common, Pharmacology, Sex Characteristics, Receptors, Dopamine D2, business.industry, Dopaminergic, Receptors, Dopamine D3, Middle Aged, 030227 psychiatry, Endocrinology, Fallypride, Positron-Emission Tomography, Benzamides, Ventral Striatum, Central Nervous System Stimulants, Female, business, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1bfbb74f73142952077f89984c7167c
https://doi.org/10.1007/s00213-018-5083-5

المؤلفون: David H. Zald, Ronald L. Cowan, Scott F. Perkins, Nam T. Le, Gregory R. Samanez-Larkin, Linh C. Dang, Jaime J. Castrellon

المصدر: NeuroImage. 148:123-129

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Aging, medicine.medical_specialty, Cognitive Neuroscience, Physical activity, Degeneration (medical), Striatum, Article, Midbrain, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Dopamine, Internal medicine, Dopamine receptor D2, medicine, Humans, Exercise, Aged, Aged, 80 and over, Receptors, Dopamine D2, Dopaminergic, Receptors, Dopamine D3, Brain, Middle Aged, Magnetic Resonance Imaging, Cross-Sectional Studies, 030104 developmental biology, Endocrinology, Neurology, Fallypride, Positron-Emission Tomography, Benzamides, Female, Radiopharmaceuticals, Psychology, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e9f738109e591ecc8202c6b4cc9d14
https://doi.org/10.1016/j.neuroimage.2017.01.018

المؤلفون: Shaoqing Chen, Paul Gillespie, Sung-Sau So, Steven Gregory Mischke, David Robert Bolin, Nam T. Le, Frank Mennona, Mushtaq Ahmad, Karin Conde-Knape, Charles Burghardt, Hong Wang, Shahid Tannu, Yimin Qian, Jarema Peter Kochan

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:6264-6269

مصطلحات موضوعية: Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing), chemistry.chemical_classification, Ketone, biology, High-throughput screening, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Fructose 6-phosphate, Isoquinolines, Biochemistry, Glutamine, Inhibitory Concentration 50, chemistry.chemical_compound, chemistry, Pharmacokinetics, Enzyme inhibitor, Drug Discovery, biology.protein, Molecular Medicine, Potency, Enzyme Inhibitors, Molecular Biology, Glutamine amidotransferase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ce41d6fc54e9d94c3232db8c5a857f
https://doi.org/10.1016/j.bmcl.2011.09.009

المؤلفون: Jin-Jun Liu, Christophe Michoud, Feng Chi, Yang Wen, Qing Xiang, Nam T. Le, Shaoqing Chen, Nicole Jackson, Jian Ping Lou, Li Chen, Chunlin Zhao, Achyutharao Sidduri, Louis Portland, Lyubomir T. Vassilev, Fred Konzelmann, Yingsi Chen, Christian Tovar

المصدر: Bioorganic & Medicinal Chemistry Letters. 17:2134-2138

مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Biochemistry, Chemical synthesis, Structure-Activity Relationship, Cyclin-dependent kinase, Cell Line, Tumor, CDC2 Protein Kinase, Drug Discovery, Humans, Structure–activity relationship, Protein kinase A, Protein Kinase Inhibitors, Molecular Biology, Cyclin-dependent kinase 1, biology, Chemistry, Kinase, Organic Chemistry, Thiazoles, biology.protein, Molecular Medicine, Drug Screening Assays, Antitumor, Signal transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab9e1e7142c358c44595074f3b33ef8
https://doi.org/10.1016/j.bmcl.2007.01.081

المؤلفون: Cheryl Janson, Martin Weisel, Barry Goggin, Liang Weiling, Adrian J. Fretland, Robert Francis Kester, Christine Lukacs, Edmund Lee, Jennifer Lo, J. Heather Hogg, Xiaochun Han, Kyoungja Hong, Stacy Remiszewski, Shirley Li, Ann Polonskaia, John Anthony Moliterni, Kang Le, Lin Gao, Nam T. Le, Christophe Michoud, A. Schutt, Shahid Tannu, Andrew F. Donnell, Shaoqing Chen, Louis J. Lombardo, Steven Gregory Mischke, Mark T. Dvorozniak, Yan Lou, Christine Tardell, Kenneth Carey Rupert, Doug Aguilar, Dave S. Solis

المصدر: Journal of medicinal chemistry. 56(20)

مصطلحات موضوعية: Models, Molecular, Cell Survival, Ubiquitin-Protein Ligases, Blotting, Western, Mice, Nude, Apoptosis, X-Linked Inhibitor of Apoptosis Protein, Inhibitor of apoptosis, Crystallography, X-Ray, Inhibitor of Apoptosis Proteins, Mice, Heterocyclic Compounds, Cell Line, Tumor, Drug Discovery, Animals, Humans, Caspase, Caspase-9, Caspase 7, Benzodiazepinones, Alanine, biology, Molecular Structure, Chemistry, Caspase 3, Xenograft Model Antitumor Assays, In vitro, Cell biology, XIAP, Protein Structure, Tertiary, Models, Chemical, Cell culture, Cancer cell, biology.protein, Molecular Medicine, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54996c22c1d8fb8749b427ec42349aeb
https://pubmed.ncbi.nlm.nih.gov/24093940

المؤلفون: Nam T. Le, Kang Le, Zhi Chen, Yingsi Chen, Tom Nevins, Shaoqing Chen, Steve Mischke, David Joseph Bartkovitz, Jianping Cai, Goli Naderi-Oboodi, Weiguo Qing, Xin-Jie Chu, John Frederick Boylan, Kin Chun Luk, Yi Chen, Peter Michael Wovkulich

المصدر: Bioorganicmedicinal chemistry letters. 22(2)

مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Cell Cycle Proteins, Polo-like kinase, Protein Serine-Threonine Kinases, Biochemistry, PLK1, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Cell Line, Tumor, Proto-Oncogene Proteins, Drug Discovery, Potency, Structure–activity relationship, Animals, Humans, Molecular Biology, Protein Kinase Inhibitors, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, Kinase, Chemistry, Organic Chemistry, Stereoisomerism, Azepines, Neoplasms, Experimental, In vitro, Pyrimidines, Cell culture, Molecular Medicine, Lead compound

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edcb14437e7b95274bb866375731eb92
https://pubmed.ncbi.nlm.nih.gov/22172702