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1
المؤلفون: Colin, Zhang, Meizhong, Xu, Chunhong, He, Jincong, Zhuo, David M, Burns, Ding-Quan, Qian, Qiyan, Lin, Yun-Long, Li, Lihua, Chen, Eric, Shi, Costas, Agrios, Linkai, Weng, Vaqar, Sharief, Ravi, Jalluri, Yanlong, Li, Peggy, Scherle, Sharon, Diamond, Deborah, Hunter, Maryanne, Covington, Cindy, Marando, Richard, Wynn, Kamna, Katiyar, Nancy, Contel, Kris, Vaddi, Swamy, Yeleswaram, Gregory, Hollis, Reid, Huber, Steve, Friedman, Brian, Metcalf, Wenqing, Yao
المصدر: SSRN Electronic Journal.
مصطلحات موضوعية: Metabolic Syndrome, History, Hydrocortisone, Polymers and Plastics, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Industrial and Manufacturing Engineering, Diabetes Mellitus, Type 2, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Drug Discovery, Humans, Molecular Medicine, Enzyme Inhibitors, Business and International Management, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3692552a04b6f880ed62ecd30b202590
https://doi.org/10.2139/ssrn.4056120 -
2
المؤلفون: Brian Metcalf, Sharon Diamond, Taisheng Huang, Lixin Shao, Swamy Yeleswaram, D. Joseph Rogier, Greg Hollis, Michael Xia, Ke Zhang, Ganfeng Cao, Nancy Contel, Lingquan Kong, Peggy Scherle, Maryanne Covington, Tom Emm, Robert Hughes, Joseph Glenn, Robert C. Newton, Kris Vaddi, Changsheng Zheng, Lou Storace, Chu-Biao Xue, Rajan Anand, Hao Feng, Meloni David, Anlai Wang, Mei Li, Philip A. Morton, Robinson Darius J, Qi Han, Rajesh V. Devraj, Yingxin Zhang
المصدر: ACS Medicinal Chemistry Letters. 2:913-918
مصطلحات موضوعية: CCR2, biology, business.industry, Organic Chemistry, High selectivity, hERG, Antagonist, Pharmacology, Biochemistry, In vitro, Bioavailability, In vivo, Drug Discovery, Ccr2 antagonist, biology.protein, Medicine, business
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3
المؤلفون: Beth Thomas, Gregory Hollis, Patrick J. Haley, Brian Metcalf, Kris Vaddi, Claire L. Neilan, Jack G. Shi, Paul Collier, Nancy Contel, Steven Friedman, Swamy Yeleswaram, Jordan S. Fridman, Denise Hertel, Robert Collins, Stacey Shepard, Peggy Scherle, Timothy Burn, Robert C. Newton, James D. Rodgers
المصدر: Journal of Investigative Dermatology. 131:1838-1844
مصطلحات موضوعية: Keratinocytes, STAT3 Transcription Factor, Thymic stromal lymphopoietin, Swine, T-Lymphocytes, medicine.medical_treatment, Dermatology, Biochemistry, stat, Dermatitis, Atopic, Pathogenesis, Mice, Psoriasis, Nitriles, Ustekinumab, medicine, Animals, Humans, Hypersensitivity, Delayed, Phosphorylation, Protein Kinase Inhibitors, Molecular Biology, Cells, Cultured, business.industry, Monocyte, Janus Kinase 1, Cell Biology, Atopic dermatitis, Janus Kinase 2, medicine.disease, Pyrimidines, Cytokine, medicine.anatomical_structure, Epidermal Cells, Immunology, Pyrazoles, Swine, Miniature, Chemokines, business, Signal Transduction, medicine.drug
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4
المؤلفون: Francesco Passamonti, Bijoyesh Mookerjee, Nancy Contel, Mario Cazzola, Hagop M. Kantarjian, Srdan Verstovsek, Victor Sandor, Peter Rosen, Elisa Rumi, Tiziano Barbui, Alessandro Rambaldi, Giovanni Barosi, Alessandro M. Vannucchi, Lisa Pieri, Chiara Elena, Elisabetta Gattoni, Paola Guglielmelli, Shui He
المصدر: Cancer
مصطلحات موضوعية: Oncology, Male, Cancer Research, Ruxolitinib, ruxolitinib, myeloproliferative neoplasm, Phases of clinical research, Hematocrit, Polycythemia vera, hemic and lymphatic diseases, 80 and over, Hydroxyurea, Aged, 80 and over, Janus kinase 2, medicine.diagnostic_test, biology, Anemia, Middle Aged, Janus kinase (JAK) inhibitor, Female, medicine.drug, Adult, medicine.medical_specialty, Drug-Related Side Effects and Adverse Reactions, Young Adult, phase 2, polycythemia vera, Aged, Granulocytes, Humans, Janus Kinase 1, Janus Kinase 2, Polycythemia Vera, Pyrazoles, Thrombocytopenia, Refractory, Internal medicine, Nitriles, medicine, Myeloproliferative neoplasm, business.industry, Contraindications, Original Articles, medicine.disease, Clinical trial, Pyrimidines, Immunology, biology.protein, business
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5
المؤلفون: Frédéric Baribaud, Philip L Liu, Peggy Scherle, Brian Metcalf, Maryanne B. Covington, Gregory Hollis, Steve Friedman, Timothy Burn, Niu Shin, Philip Czerniak, Susan Erickson-Viitanen, Kris Vaddi, Nancy Contel, Kathy Wang, Robert Newton, Naiming Zhou, Swamy Yeleswaram, Yanlong Li, Chu-Biao Xue, Vasudha Garlapati, Kim Solomon, Beth Thomas
المصدر: The Journal of pharmacology and experimental therapeutics. 338(1)
مصطلحات موضوعية: Receptors, CCR5, Stereochemistry, Anti-HIV Agents, Allosteric regulation, Context (language use), HIV Infections, CCR5 receptor antagonist, Monocytes, Piperazines, Chemokine receptor, Cell Movement, Radioligand, medicine, Animals, Humans, Binding site, Cells, Cultured, Pharmacology, Dose-Response Relationship, Drug, Chemistry, Ligand binding assay, Macaca fascicularis, HEK293 Cells, Pyrimidines, CCR5 Receptor Antagonists, HIV-1, Molecular Medicine, Vicriviroc, Allosteric Site, medicine.drug, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc42edb4cc7e96ce80679d5240d5207
https://pubmed.ncbi.nlm.nih.gov/21459966 -
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المؤلفون: Greg Hollis, Changsheng Zheng, Hao Feng, Mei Li, Peggy Scherle, Taisheng Huang, Joseph Glenn, Chu-Biao Xue, Kris Vaddi, Lixin Shao, Brian Metcalf, Tom Emm, Nancy Contel, Ke Zhang, Ganfeng Cao, Dilip P. Modi, Lou Storace, Anlai Wang, Sharon Diamond, Robert C. Newton, Chen Lihua, Steven Friedman, Rajan Anand, Vaqar Sharief, Lingquan Kong, Hiroyuki Tanaka, Meloni David, Maryanne Covington, Michael Xia, Laurine G. Galya, Robinson Darius J, Qi Han, Swamy Yeleswaram, Yingxin Zhang
المصدر: ACS medicinal chemistry letters. 2(6)
مصطلحات موضوعية: CCR2, Chemokine, biology, business.industry, Organic Chemistry, hERG, Antagonist, Chemotaxis, Pharmacology, Biochemistry, Chemokine receptor, Drug Discovery, biology.protein, Medicine, business, Receptor, Antagonism
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7
المؤلفون: Gregory Hollis, Tom Emm, Joseph Glenn, Kris Vaddi, Rajan Anand, Brian Metcalf, Douglas Keller, Peggy Scherle, Chen Lihua, Ke Zhang, Ganfeng Cao, Taisheng Huang, Sharon Diamond, Kim Solomon, Robert C. Newton, Chu-Biao Xue, Jiacheng Zhou, Meloni David, Steven Friedman, Nancy Contel, Anlai Wang, Changsheng Zheng, Bitao Zhao, Swamy Yeleswaram, Hao Feng, Ling Kong, Laurine G. Galya, Fredric Baribaud, Michael Xia, Niu Shin, Mei Li
مصطلحات موضوعية: Anti hiv 1, business.industry, Organic Chemistry, Indane, Antagonist, virus diseases, CCR5 receptor antagonist, Pharmacology, Biochemistry, Entry inhibitor, Bioavailability, Receptor selectivity, Safety profile, chemistry.chemical_compound, chemistry, Drug Discovery, medicine, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0734e1759782a0457a497299b8c836bd
https://europepmc.org/articles/PMC4007949/ -
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المؤلفون: Bijoyesh Mookerjee, Peter Rosen, Giovanni Barosi, Tiziano Barbui, Elisabetta Gattoni, Lisa Pieri, Mario Cazzola, Francesco Passamonti, Nancy Contel, Elisa Rumi, Alessandro Rambaldi, Hagop M. Kantarjian, Alessandro M. Vannucchi, Shui He, Srdan Verstovsek
المصدر: Blood. 120:804-804
مصطلحات موضوعية: medicine.medical_specialty, Ruxolitinib, medicine.diagnostic_test, business.industry, Anemia, Essential thrombocythemia, Immunology, Cell Biology, Hematology, Phlebotomy, Hematocrit, medicine.disease, Biochemistry, Gastroenterology, Surgery, Polycythemia vera, Internal medicine, medicine, Leukocytosis, medicine.symptom, Myelofibrosis, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::69ccd24200b439f7e718aa158b20e9c5
https://doi.org/10.1182/blood.v120.21.804.804 -
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المؤلفون: Lisa Pieri, Srdan Verstovsek, Enrico Tagliarico, Roberta Zini, Nancy Contel, Alberto Bosi, Ruggiero Norfo, Paola Guglielmelli, Alessandro M. Vannucchi, Timothy Burn, Kris Vaddi, Rossella Manfredini
المصدر: ResearcherID
مصطلحات موضوعية: Oncology, Ruxolitinib, medicine.medical_specialty, business.industry, Essential thrombocythemia, Immunology, Phases of clinical research, Cell Biology, Hematology, medicine.disease, Biochemistry, Polycythemia vera, Internal medicine, microRNA, medicine, In patient, Clinical efficacy, DNA microarray, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e4225155c4e224b6a914697b079847
https://doi.org/10.1182/blood.v118.21.3852.3852 -
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المؤلفون: Alessandro M. Vannucchi, Kris Vaddi, Lee P. Schacter, Tiziano Barbui, Elisa Rumi, Reid Huber, Elisabetta Gattoni, Richard S. Levy, Elisabetta Antonioli, Nancy Contel, Lisa Pieri, Srdan Verstovsek, Edward C Bradley, Giovanni Barosi, Francesco Passamonti, William M. Garrett, Alessandro Rambaldi, Mario Cazzola, Peter J. Rosen, Hagop M. Kantarjian, Victor Sandor
المصدر: Blood. 116:313-313
مصطلحات موضوعية: medicine.medical_specialty, Leukopenia, Thrombocytosis, Essential thrombocythemia, business.industry, Immunology, Phases of clinical research, Cell Biology, Hematology, Phlebotomy, Neutropenia, medicine.disease, Biochemistry, Gastroenterology, Surgery, Polycythemia vera, Internal medicine, medicine, Leukocytosis, medicine.symptom, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cfb6e402372ef164a10ec23c173b4393
https://doi.org/10.1182/blood.v116.21.313.313