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1
المؤلفون: Lee-Yuh Pai, Aaron Corona, Harry R. Chobanian, John P. Felix, Matthew J. Clements, Karen Owens, Haifeng Tang, Brande Thomas-Fowlkes, Kathleen A. Sullivan, Alexander Pasternak, Caryn Hampton, Jessica Frie, Vincent Tong, Ron Ferguson, Jessica Liu, Birgit T. Priest, Barbara Pio, Yan Guo, Elizabeth Joshi, Nardos Teumelsan, Ling Xu, Martin Köhler, Joseph M. Metzger, Zach Guo, Kevin M. Maloney
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:1109-1114
مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, hERG, Pharmaceutical Science, Diuresis, Biochemistry, Natriuresis, Sulfone, 03 medical and health sciences, chemistry.chemical_compound, Heterocyclic Compounds, Rats, Inbred SHR, Drug Discovery, medicine, Animals, Moiety, Organic chemistry, Sulfones, Enzyme Inhibitors, Potassium Channels, Inwardly Rectifying, Diuretics, Molecular Biology, biology, Chemistry, Organic Chemistry, Rats, 030104 developmental biology, Drug Design, ROMK, biology.protein, Molecular Medicine, Diuretic, Selectivity
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2
المؤلفون: Shawn P. Walsh, Lee-Yuh Pai, Yuping Zhu, John P. Felix, Caryn Hampton, Xiaoyan Zhou, Melba Hernandez, Brande Thomas-Fowlkes, Richard M. Brochu, Nardos Teumelsan, Gregory J. Kaczorowski, Emma R. Parmee, Maria L. Garcia, Alexander Pasternak, Jinlong Jiang, Sookhee Ha, Sophie Roy, Kathleen A. Sullivan, Haifeng Tang, Lihu Yang, Karen Owens, Reynalda K. de Jesus, Xin Gu, Birgit T. Priest, Barbara Pio, Fa-Xiang Ding, Andrew M. Swensen, Magdalena Alonso-Galicia, Aurash Shahripour, Juliann Ehrhart, Timothy Bailey
المصدر: Bioorganic & Medicinal Chemistry Letters. 26:5695-5702
مصطلحات موضوعية: 0301 basic medicine, QTC PROLONGATION, Clinical Biochemistry, hERG, Pharmaceutical Science, Pharmacology, Biochemistry, Dog model, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Dogs, 0302 clinical medicine, Transcriptional Regulator ERG, Pharmacokinetics, In vivo, Oxazines, Drug Discovery, Animals, Humans, Potassium Channels, Inwardly Rectifying, Molecular Biology, Heart Failure, biology, Chemistry, Organic Chemistry, Macaca mulatta, Small molecule, Diuresis, Piperazine, 030104 developmental biology, 030220 oncology & carcinogenesis, Hypertension, ROMK, biology.protein, Molecular Medicine
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3
المؤلفون: Michael J. Forrest, John P. Felix, Lee-Yuh Pai, Melba Hernandez, Yuping Zhu, Aaron Corona, Joseph M. Metzger, Gregory J. Kaczorowski, Nardos Teumelsan, Lihu Yang, Karen Owens, Timothy Bailey, Caryn Hampton, Vincent Tong, Alexander Pasternak, Brande Thomas-Fowlkes, Shawn P. Walsh, Emma R. Parmee, Haifeng Tang, Richard M. Brochu, Maria L. Garcia, Xiaoyan Zhou, Magdalena Alonso-Galicia, Sophie Roy, Birgit T. Priest, Andrew M. Swensen, Aurash Shahripour
المصدر: ACS Medicinal Chemistry Letters. 7:697-701
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Kidney, biology, Chemistry, Organic Chemistry, hERG, Diuresis, Nephron, Pharmacology, Biochemistry, Natriuresis, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Internal medicine, Drug Discovery, medicine, biology.protein, Loop of Henle, ROMK, Thiazide, medicine.drug
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4
المؤلفون: Lee-Yuh Pai, Yuping Zhu, Richard Visconti, Xiaoyan Zhou, John P. Felix, Melba Hernandez, Jing Chen, Michael Margulis, Nardos Teumelsan, Sophie Roy, Kathleen A. Sullivan, Jessica Liu, Joseph M. Metzger, Aaron Corona, Gregory J. Kaczorowski, Maria L. Garcia, Lihu Yang, Shawn P. Walsh, Birgit T. Priest, Alexander Pasternak, Caryn Hampton, Emma R. Parmee, Vincent Tong, Brande Thomas-Fowlkes, Haifeng Tang, Magdalena Alonso-Galicia, Kashmira Shah, Michael J. Forrest, Richard M. Brochu, Ross Bentley, Sookhee Ha, Karen Owens, Aurash Shahripour, Andrew M. Swensen, Jessica Frie, Adam B. Weinglass, Timothy Bailey
المصدر: ACS Medicinal Chemistry Letters. 6:747-752
مصطلحات موضوعية: Pharmacokinetics, Chemistry, Pharmacodynamics, Organic Chemistry, Drug Discovery, ROMK, Pharmacology, Biochemistry
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5
المؤلفون: Shawn P. Walsh, Jessica Frie, Nardos Teumelsan, Maria L. Garcia, Karen Owens, Sophie Roy, Caryn Hampton, Reynalda K. de Jesus, Birgit T. Priest, Magdalena Alonso-Galicia, Aurash Shahripour, Richard M. Brochu, Juliann Ehrhart, Andrew M. Swensen, Haifeng Tang, Timothy Bailey, Alexander Pasternak, Lee-Yuh Pai, Yuping Zhu, Lihu Yang, Gregory J. Kaczorowski, John P. Felix, Melba Hernandez, Brande Thomas-Fowlkes, Xiaoyan Zhou
المصدر: Bioorganicmedicinal chemistry letters. 26(9)
مصطلحات موضوعية: 0301 basic medicine, ERG1 Potassium Channel, medicine.medical_treatment, Clinical Biochemistry, hERG, Pharmaceutical Science, Pharmacology, Biochemistry, Piperazines, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, In vivo, Heterocyclic Compounds, Drug Discovery, medicine, Potency, Structure–activity relationship, Molecular Biology, biology, Chemistry, Organic Chemistry, Small molecule, Piperazine, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, ROMK, Molecular Medicine, Diuretic
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6
المؤلفون: Nardos Teumelsan, Xuefei Huang
المصدر: The Journal of Organic Chemistry. 72:8976-8979
مصطلحات موضوعية: chemistry.chemical_classification, Glycosylation, Anomer, Stereochemistry, Molecular Sequence Data, Organic Chemistry, Diastereomer, Oligosaccharides, Stereoisomerism, Glycosidic bond, Oligosaccharide, Chemical synthesis, Article, chemistry.chemical_compound, Carbohydrate Sequence, chemistry, Carbohydrate Conformation, Carbohydrate conformation, Mannose
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7
المؤلفون: Nardos Teumelsan, Xuefei Huang, Lijun Huang
المصدر: Chemistry - A European Journal. 12:5246-5252
مصطلحات موضوعية: Spectrometry, Mass, Electrospray Ionization, Magnetic Resonance Spectroscopy, Molecular Sequence Data, Thioacetal, Carboxylic Acids, Oligosaccharides, Alcohol, Article, Antioxidants, Catalysis, Cyclic N-Oxides, chemistry.chemical_compound, Hyaluronic acid, Benzyl Compounds, Organic chemistry, Chondroitin, Glycosaminoglycans, chemistry.chemical_classification, Perchlorates, Primary (chemistry), Organic Chemistry, Aromaticity, Glycosidic bond, General Medicine, General Chemistry, Oxidation of primary alcohols to carboxylic acids, Carbohydrate Sequence, chemistry, Alcohols, Alcohol oxidation, Oxidation-Reduction
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8
المؤلفون: Nardos Teumelsan, Alexander Pasternak, John P. Felix, Yan Yan, Reynalda K. de Jesus, Brande Thomas-Fowlkes, Maria L. Garcia, Gregory J. Kaczorowski, Lihu Yang, Haifeng Tang, Sophie Roy, Richard M. Brochu, Jessica Liu, Sookhee Ha, Shawn P. Walsh, Karen Owens, Birgit T. Priest, Magdalena Alonso-Galicia, Aurash Shahripour, Martin Köhler, Sander G. Mills, Yuping Zhu, Timothy Bailey
مصطلحات موضوعية: biology, Inward-rectifier potassium ion channel, business.industry, Organic Chemistry, hERG, Drug target, RENAL OUTER-MEDULLARY POTASSIUM CHANNEL, Pharmacology, Biochemistry, Small molecule, Potassium channel, In vivo, Drug Discovery, ROMK, biology.protein, Medicine, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fdeb1e8a7f5b59825e6d5dc44ae674d
https://europepmc.org/articles/PMC4025819/ -
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المؤلفون: Nardos Teumelsan, Xuefei Huang
المصدر: ChemInform. 39
مصطلحات موضوعية: Stereochemistry, Chemistry, General Medicine
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10دورية أكاديمية
المؤلفون: Lijun Huang, Nardos Teumelsan, Xuefei Huang
المصدر: Chemistry - A European Journal; Jul2006, Vol. 12 Issue 20, p5246-5252, 7p