المؤلفون: Liang SQ; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Navia AW; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA., Ramseier M; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA., Zhou X; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Martinez M; Departments of Pediatrics and Cell Biology and Human Anatomy, School of Medicine, and California National Primate Research Center, University of California, Davis, California, USA., Lee C; Departments of Pediatrics and Cell Biology and Human Anatomy, School of Medicine, and California National Primate Research Center, University of California, Davis, California, USA., Zhou C; Horae Gene Therapy Center and Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Wu J; Department of Pediatrics, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Xie J; Horae Gene Therapy Center and Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Viral Vector Core, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Su Q; Horae Gene Therapy Center and Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Viral Vector Core, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Wang D; Horae Gene Therapy Center and Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Flotte TR; Horae Gene Therapy Center and Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Anderson DG; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Harvard and MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Tarantal AF; Departments of Pediatrics and Cell Biology and Human Anatomy, School of Medicine, and California National Primate Research Center, University of California, Davis, California, USA., Shalek AK; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA., Gao G; Horae Gene Therapy Center and Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Viral Vector Core, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Xue W; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA.

المصدر: Human gene therapy [Hum Gene Ther] 2024 Jul 03. Date of Electronic Publication: 2024 Jul 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: M.A. Liebert Country of Publication: United States NLM ID: 9008950 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7422 (Electronic) Linking ISSN: 10430342 NLM ISO Abbreviation: Hum Gene Ther Subsets: MEDLINE

المؤلفون: Winter PS; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Institute for Medical Engineering & Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Ramseier ML; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Institute for Medical Engineering & Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Navia AW; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Institute for Medical Engineering & Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Saksena S; Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, USA.; Computational and Systems Biology Program, MIT, Cambridge, MA, USA., Strouf H; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA., Senhaji N; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., DenAdel A; Center for Computational Molecular Biology, Brown University, Providence, RI, USA.; Department of Biostatistics, Brown University, Providence, RI, USA., Mirza M; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA., An HH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Bilal L; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA., Dennis P; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Leahy CS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Shigemori K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Galves-Reyes J; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Institute for Medical Engineering & Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Zhang Y; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Department of Biological Engineering, MIT, Cambridge, MA, USA., Powers F; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Mulugeta N; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Institute for Medical Engineering & Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Gupta AJ; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA., Calistri N; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA., Van Scoyk A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Jones K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Liu H; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Stevenson KE; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA USA., Ren S; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA USA., Luskin MR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Couturier CP; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Institute for Medical Engineering & Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Amini AP; Microsoft Research, Cambridge, MA, USA., Raghavan S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Kimmerling RJ; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA., Stevens MM; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA., Crawford L; Center for Computational Molecular Biology, Brown University, Providence, RI, USA.; Department of Biostatistics, Brown University, Providence, RI, USA.; Microsoft Research, Cambridge, MA, USA., Weinstock DM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Current Address: Merck and Co., Rahway, NJ, USA., Manalis SR; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biological Engineering, MIT, Cambridge, MA, USA., Shalek AK; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Institute for Medical Engineering & Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Murakami MA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 10. Date of Electronic Publication: 2024 Jun 10.

نوع المنشور: Journal Article; Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Ziegler CGK; Program in Health Sciences & Technology, Harvard Medical School & MIT, Boston, Massachusetts, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Harvard Graduate Program in Biophysics, Harvard University, Cambridge, Massachusetts, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Owings AH; Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA., Galeas-Pena M; Department of Medicine, Section of Gastroenterology and Hepatology, Tulane University School of Medicine, New Orleans, Los Angeles, USA., Kazer SW; Program in Immunology, Harvard Medical School, Boston, Massachusetts, USA.; Division of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts, USA., Miao VN; Program in Health Sciences & Technology, Harvard Medical School & MIT, Boston, Massachusetts, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Navia AW; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Tang Y; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, Massachusetts, USA., Bromley JD; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Department of Microbiology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Lotfy P; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, Massachusetts, USA., Sloan M; Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA., Laird H; Division of Digestive Diseases, University of Mississippi Medical Center, Jackson, Mississippi, USA., Williams HB; Division of Digestive Diseases, University of Mississippi Medical Center, Jackson, Mississippi, USA., George M; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Drake RS; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Pride Y; Division of Digestive Diseases, University of Mississippi Medical Center, Jackson, Mississippi, USA., Abraham GE 3rd; Division of Pulmonary, Critical Care, and Sleep Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA., Senitko M; Division of Pulmonary, Critical Care, and Sleep Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA., Robinson TO; Division of Digestive Diseases, University of Mississippi Medical Center, Jackson, Mississippi, USA., Diamond G; Department of Oral Immunology and Infectious Diseases, University of Louisville, Louisville, Kentucky, USA., Lionakis MS; Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology (LCIM), National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, Maryland, USA., Shalek AK; Program in Health Sciences & Technology, Harvard Medical School & MIT, Boston, Massachusetts, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Harvard Graduate Program in Biophysics, Harvard University, Cambridge, Massachusetts, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Program in Immunology, Harvard Medical School, Boston, Massachusetts, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Harvard Stem Cell Institute, Cambridge, Massachusetts, USA., Ordovas-Montanes J; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Immunology, Harvard Medical School, Boston, Massachusetts, USA.; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, Massachusetts, USA.; Harvard Stem Cell Institute, Cambridge, Massachusetts, USA., Horwitz BH; Program in Immunology, Harvard Medical School, Boston, Massachusetts, USA.; Division of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, Massachusetts, USA., Glover SC; Division of Digestive Diseases, University of Mississippi Medical Center, Jackson, Mississippi, USA.; Center for Immunology and Microbial Research, Department of Cell & Molecular Biology, University of Mississippi Medical Center, Jackson, Mississippi, USA.

المصدر: Microbiology spectrum [Microbiol Spectr] 2024 Jun 04; Vol. 12 (6), pp. e0351623. Date of Electronic Publication: 2024 Apr 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2165-0497 (Electronic) Linking ISSN: 21650497 NLM ISO Abbreviation: Microbiol Spectr Subsets: MEDLINE

مواضيع طبية MeSH: Interleukin-17*/metabolism , Interleukin-17*/genetics , Interleukin-17*/immunology , COVID-19*/immunology , Coinfection*/immunology , Coinfection*/microbiology , Coinfection*/virology , Interferon Type I*/metabolism , Interferon Type I*/immunology , SARS-CoV-2*/immunology , Epithelial Cells*/immunology , Epithelial Cells*/microbiology, Humans ; Male ; Middle Aged ; Female ; Adult ; Nasal Mucosa/immunology ; Nasal Mucosa/microbiology ; Aged ; Nasopharynx/microbiology ; Candidiasis/immunology ; Candidiasis/microbiology ; Mycoses/immunology

المؤلفون: Nwizu C; Center for Computational Molecular Biology, Brown University, Providence, RI, USA.; Warren Alpert Medical School of Brown University, Providence, RI, USA., Hughes M; Microsoft Research, Cambridge, MA, USA., Ramseier ML; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Navia AW; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Shalek AK; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA., Fusi N; Microsoft Research, Cambridge, MA, USA., Raghavan S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Winter PS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Amini AP; Microsoft Research, Cambridge, MA, USA., Crawford L; Center for Computational Molecular Biology, Brown University, Providence, RI, USA.; Microsoft Research, Cambridge, MA, USA.; Department of Biostatistics, Brown University, Providence, RI, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Feb 12. Date of Electronic Publication: 2024 Feb 12.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Williams HL; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Dias Costa A; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Zhang J; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Raghavan S; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Winter PS; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts.; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts., Kapner KS; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Ginebaugh SP; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Väyrynen SA; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Väyrynen JP; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.; Cancer and Translational Medicine Research Unit, Medical Research Center Oulu, Oulu University Hospital, University of Oulu, Oulu, Finland., Yuan C; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Navia AW; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts.; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts., Wang J; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Yang A; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Bosse TL; Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Kalekar RL; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Lowder KE; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Lau MC; Department of Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts., Elganainy D; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Morales-Oyarvide V; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Rubinson DA; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Singh H; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Perez K; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Cleary JM; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Clancy TE; Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts., Wang J; Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts., Mancias JD; Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts., Brais LK; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Hill ER; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Kozak MM; Department of Radiation Oncology, Stanford Cancer Institute, Stanford, California., Linehan DC; Department of Surgery, University of Rochester Medical Center, Rochester, New York., Dunne RF; Department of Medicine, Division of Hematology and Oncology, Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York., Chang DT; Department of Radiation Oncology, Stanford Cancer Institute, Stanford, California., Koong AC; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Hezel AF; Department of Medicine, Division of Hematology and Oncology, Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York., Hahn WC; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Shalek AK; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts.; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts., Aguirre AJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Nowak JA; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Wolpin BM; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

المصدر: Cancer research [Cancer Res] 2023 Feb 03; Vol. 83 (3), pp. 441-455.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Pancreatic Neoplasms*/pathology , Carcinoma, Pancreatic Ductal*/genetics , Carcinoma, Pancreatic Ductal*/pathology, Humans ; Prognosis ; Phenotype ; RNA ; Gene Expression Regulation, Neoplastic ; Claudins

المؤلفون: Ziegler CGK; Program in Health Sciences & Technology, Harvard Medical School & MIT, Boston, MA, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Graduate Program in Biophysics, Harvard University, Cambridge, MA, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA., Owings AH; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Miao VN; Program in Health Sciences & Technology, Harvard Medical School & MIT, Boston, MA, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA., Navia AW; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA., Tang Y; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA, USA., Bromley JD; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Microbiology, Massachusetts Institute of Technology, Cambridge, MA, USA., Lotfy P; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA, USA., Sloan M; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Laird H; Division of Digestive Diseases, University of Mississippi Medical Center, Jackson, MS, USA., Williams HB; Division of Digestive Diseases, University of Mississippi Medical Center, Jackson, MS, USA., George M; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA., Drake RS; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA., Pride Y; Division of Digestive Diseases, University of Mississippi Medical Center, Jackson, MS, USA., Abraham GE 3rd; Division of Pulmonary, Critical Care, and Sleep Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Senitko M; Division of Pulmonary, Critical Care, and Sleep Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Robinson TO; Division of Digestive Diseases, University of Mississippi Medical Center, Jackson, MS, USA., Lionakis MS; Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology (LCIM), National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, MD, USA., Shalek AK; Program in Health Sciences & Technology, Harvard Medical School & MIT, Boston, MA, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Graduate Program in Biophysics, Harvard University, Cambridge, MA, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Program in Immunology, Harvard Medical School, Boston, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA., Ordovas-Montanes J; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA, USA.; Program in Immunology, Harvard Medical School, Boston, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA., Horwitz BH; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA, USA.; Program in Immunology, Harvard Medical School, Boston, MA, USA.; Division of Emergency Medicine, Boston Children's Hospital, Boston, MA, USA., Glover SC; Division of Digestive Diseases, University of Mississippi Medical Center, Jackson, MS, USA.; Center for Immunology and Microbial Research, Department of Cell & Molecular Biology, University of Mississippi Medical Center, Jackson, MS, USA.

المصدر: MedRxiv : the preprint server for health sciences [medRxiv] 2022 Oct 26. Date of Electronic Publication: 2022 Oct 26.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE

المؤلفون: Alvarez-Breckenridge C; Departments of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts., Markson SC; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.; Evergrande Center for Immunological Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts.; Broad Institute, Harvard University and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts., Stocking JH; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Nayyar N; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Lastrapes M; Broad Institute, Harvard University and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Strickland MR; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts.; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., Kim AE; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts.; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., de Sauvage M; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Dahal A; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Larson JM; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Mora JL; Broad Institute, Harvard University and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts.; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., Navia AW; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, Massachusetts.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.; Ragon Institute, Harvard University, Massachusetts Institute of Technology, and Massachusetts General Hospital, Cambridge, Massachusetts., Klein RH; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Kuter BM; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Gill CM; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Bertalan M; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Shaw B; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Kaplan A; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Subramanian M; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Jain A; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Kumar S; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Danish H; Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Medical Center, New York, New York., White M; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Shahid O; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts., Pauken KE; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.; Evergrande Center for Immunological Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts., Miller BC; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.; Evergrande Center for Immunological Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts.; Broad Institute, Harvard University and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Frederick DT; Division of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts., Hebert C; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Shaw M; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Martinez-Lage M; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Frosch M; C. S. Kubik Laboratory for Neuropathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Wang N; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Gerstner E; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., Nahed BV; Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts., Curry WT; Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts., Carter B; Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts., Cahill DP; Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts., Boland GM; Division of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts., Izar B; Division of Hematology and Oncology, Columbia University Irving Medical Center, New York, New York.; Columbia Center for Translational Immunology, New York, New York., Davies MA; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Sharpe AH; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.; Evergrande Center for Immunological Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts.; Broad Institute, Harvard University and Massachusetts Institute of Technology, Cambridge, Massachusetts., Suvà ML; Broad Institute, Harvard University and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Sullivan RJ; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts.; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., Brastianos PK; Broad Institute, Harvard University and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts.; Massachusetts General Hospital Cancer Center, Boston, Massachusetts., Carter SL; Broad Institute, Harvard University and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts.

المصدر: Cancer immunology research [Cancer Immunol Res] 2022 Aug 03; Vol. 10 (8), pp. 996-1012.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE

مواضيع طبية MeSH: Brain Neoplasms* , Melanoma*, Humans ; Immune Checkpoint Inhibitors ; Tumor Microenvironment

المؤلفون: Raghavan S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Winter PS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: pswinter@mit.edu., Navia AW; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Williams HL; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA., DenAdel A; Center for Computational Molecular Biology, Brown University, Providence, RI 02912, USA; Division of Applied Mathematics, Brown University, Providence, RI 02912, USA., Lowder KE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Galvez-Reyes J; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Kalekar RL; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Mulugeta N; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Kapner KS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Raghavan MS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Borah AA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Liu N; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Väyrynen SA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA., Costa AD; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA., Ng RWS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Wang J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Hill EK; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Ragon DY; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Brais LK; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Jaeger AM; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Spurr LF; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Li YY; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Cherniack AD; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard Medical School, Boston, MA 02115, USA., Booker MA; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Cohen EF; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Tolstorukov MY; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Wakiro I; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Rotem A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Cancer Genomics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Johnson BE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Center for Cancer Genomics, Dana-Farber Cancer Institute, Boston, MA 02215, USA., McFarland JM; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Sicinska ET; Harvard Medical School, Boston, MA 02115, USA; Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Jacks TE; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Sullivan RJ; Harvard Medical School, Boston, MA 02115, USA; Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA., Shapiro GI; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Clancy TE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA., Perez K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Rubinson DA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Ng K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Cleary JM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Crawford L; Center for Computational Molecular Biology, Brown University, Providence, RI 02912, USA; Department of Biostatistics, Brown University, Providence, RI 02912, USA; Microsoft Research New England, Cambridge, MA 02142, USA., Manalis SR; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA., Nowak JA; Harvard Medical School, Boston, MA 02115, USA; Center for Cancer Genomics, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA., Wolpin BM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Hahn WC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Aguirre AJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA. Electronic address: andrew_aguirre@dfci.harvard.edu., Shalek AK; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard Medical School, Boston, MA 02115, USA; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA. Electronic address: shalek@mit.edu.

المصدر: Cell [Cell] 2021 Dec 09; Vol. 184 (25), pp. 6119-6137.e26.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Tumor Microenvironment*, Biomarkers, Tumor/*metabolism , Carcinoma, Pancreatic Ductal/*metabolism , Pancreatic Neoplasms/*metabolism, Adult ; Aged ; Cell Line, Tumor ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Single-Cell Analysis

المؤلفون: Prakadan SM; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Ragon Institute, Harvard University, Massachusetts Institute of Technology, & Massachusetts General Hospital, Cambridge, MA, USA., Alvarez-Breckenridge CA; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Neurosurgery, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA., Markson SC; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, USA.; Division of Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Kim AE; Department of Medicine, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA.; Massachusetts General Hospital Cancer Center, Boston, MA, USA., Klein RH; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, USA.; Division of Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Nayyar N; Department of Medicine, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA., Navia AW; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Ragon Institute, Harvard University, Massachusetts Institute of Technology, & Massachusetts General Hospital, Cambridge, MA, USA., Kuter BM; Department of Medicine, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA., Kolb KE; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Ragon Institute, Harvard University, Massachusetts Institute of Technology, & Massachusetts General Hospital, Cambridge, MA, USA., Bihun I; Department of Medicine, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA., Mora JL; Department of Medicine, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA., Bertalan MS; Department of Medicine, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA., Shaw B; Department of Medicine, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA., White M; Department of Medicine, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA., Kaplan A; Department of Medicine, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA., Stocking JH; Department of Medicine, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA., Wadsworth MH 2nd; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Ragon Institute, Harvard University, Massachusetts Institute of Technology, & Massachusetts General Hospital, Cambridge, MA, USA., Lee EQ; Division of Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Chukwueke U; Division of Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Wang N; Massachusetts General Hospital Cancer Center, Boston, MA, USA., Subramanian M; Department of Medicine, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA., Rotem D; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, USA., Cahill DP; Department of Neurosurgery, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA., Adalsteinsson VA; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, USA., Miller JW; Department of Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA., Sullivan RJ; Department of Medicine, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA.; Massachusetts General Hospital Cancer Center, Boston, MA, USA., Carter SL; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, USA. carter.scott@jimmy.harvard.edu.; Division of Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA. carter.scott@jimmy.harvard.edu.; Department of Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA. carter.scott@jimmy.harvard.edu., Brastianos PK; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, USA. pbrastianos@mgh.harvard.edu.; Department of Medicine, Harvard Medical School & Massachusetts General Hospital, Boston, MA, USA. pbrastianos@mgh.harvard.edu.; Massachusetts General Hospital Cancer Center, Boston, MA, USA. pbrastianos@mgh.harvard.edu., Shalek AK; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA. shalek@mit.edu.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA. shalek@mit.edu.; Broad Institute, Harvard University & Massachusetts Institute of Technology, Cambridge, MA, USA. shalek@mit.edu.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. shalek@mit.edu.; Ragon Institute, Harvard University, Massachusetts Institute of Technology, & Massachusetts General Hospital, Cambridge, MA, USA. shalek@mit.edu.; Division of Health Science & Technology, Harvard Medical School, Cambridge, MA, USA. shalek@mit.edu.; Program in Computational & Systems Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. shalek@mit.edu.

المصدر: Nature communications [Nat Commun] 2021 Nov 25; Vol. 12 (1), pp. 7007. Date of Electronic Publication: 2021 Nov 25.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Bein A; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Kim S; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Goyal G; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Cao W; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Fadel C; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Naziripour A; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Sharma S; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Swenor B; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., LoGrande N; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Nurani A; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Miao VN; Program in Health Sciences & Technology, Harvard Medical School & MIT, Cambridge, MA, United States.; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Cambridge, MA, United States.; Broad Institute of MIT and Harvard, Cambridge, MA, United States.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, United States., Navia AW; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Cambridge, MA, United States.; Broad Institute of MIT and Harvard, Cambridge, MA, United States.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, United States., Ziegler CGK; Program in Health Sciences & Technology, Harvard Medical School & MIT, Cambridge, MA, United States.; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Cambridge, MA, United States.; Broad Institute of MIT and Harvard, Cambridge, MA, United States.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.; Harvard Graduate Program in Biophysics, Harvard University, Cambridge, MA, United States., Montañes JO; Broad Institute of MIT and Harvard, Cambridge, MA, United States.; Harvard Stem Cell Institute, Cambridge, MA, United States.; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA, United States., Prabhala P; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Kim MS; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Prantil-Baun R; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Rodas M; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Jiang A; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., O'Sullivan L; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Tillya G; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States., Shalek AK; Program in Health Sciences & Technology, Harvard Medical School & MIT, Cambridge, MA, United States.; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Cambridge, MA, United States.; Broad Institute of MIT and Harvard, Cambridge, MA, United States.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, United States., Ingber DE; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States.; Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, United States.; Vascular Biology Program and Department of Surgery, Harvard Medical School and Boston Children's Hospital, Boston, MA, United States.

المصدر: Frontiers in pharmacology [Front Pharmacol] 2021 Oct 25; Vol. 12, pp. 718484. Date of Electronic Publication: 2021 Oct 25 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE