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1
المؤلفون: Michael James, Gordon A. Hamlin, Stefan Gerhardt, David Ryan, Nash Ian Alun, Attilla Ting, Stephen J. Norris, Galith Karoutchi, Chris De Savi, Neil Rankine, David J. Hargreaves, Christine M. Wood, Sarah V. Baker, Philip A. MacFaul, Andrew David Morley, Kostas Karabelas
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:4215-4219
مصطلحات موضوعية: Molecular model, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Stereoisomerism, Carboxamide, Matrix Metalloproteinase Inhibitors, Crystallography, X-Ray, Biochemistry, Structure-Activity Relationship, Catalytic Domain, Matrix Metalloproteinase 13, Drug Discovery, Hydrolase, medicine, Structure–activity relationship, Protease Inhibitors, Binding site, Molecular Biology, Binding Sites, biology, Chemistry, Organic Chemistry, Zinc, Enzyme inhibitor, biology.protein, Molecular Medicine, Selectivity
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2
المؤلفون: Stefan Gerhardt, Andrew David Morley, Peter W. Kenny, Hannes Simader, Emma V. Jones, Galith Karoutchi, Stephan Krapp, Neil Rankine, Keith Oldham, Paul A. Bethel, Stefan Steinbacher, Martin Augustin
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:4622-4625
مصطلحات موضوعية: Cathepsin, biology, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Cathepsins, Biochemistry, Cathepsin B, Cathepsin L, Structure-Activity Relationship, Molecular recognition, Drug Design, Drug Discovery, Cathepsin L2, Cathepsin K, biology.protein, Molecular Medicine, Computer Simulation, Protease Inhibitors, Cathepsin V, Molecular Biology, Cathepsin S
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3
المؤلفون: Neil Rankine, Linda J. Wood, Galith Karoutchi, Michelle Coulson, Keith Oldham, Emma V. Jones, Paul A. Bethel, Stephan Krapp, Susannah J. Ford, Stefan Gerhardt, David Ryan, Matthew Grist, Peter W. Kenny, Hannes Simader, Andrew David Morley, Stuart L. Wells, Gordon A. Hamlin, Stefan Steinbacher, Jack E. Dawson, Nabil Asaad, Martin Augustin, Michael James
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:4280-4283
مصطلحات موضوعية: Cartilage, Articular, Stereochemistry, Cathepsin L, Chemistry, Pharmaceutical, Clinical Biochemistry, Pharmaceutical Science, Mice, Transgenic, Crystallography, X-Ray, Ligands, Biochemistry, Catalysis, Cathepsin B, Mice, Structure-Activity Relationship, Cathepsin O, Nitriles, Drug Discovery, Cathepsin L2, Cathepsin K, Animals, Humans, Cathepsin V, skin and connective tissue diseases, Molecular Biology, Cathepsin S, Cathepsin, biology, Chemistry, fungi, Organic Chemistry, Proteins, body regions, Drug Design, biology.protein, Molecular Medicine, Peptides
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4
المؤلفون: Peter Newham, Eleanor Henshaw, Philip A. MacFaul, Keith Oldham, Andrew David Morley, Neil Rankine, Christine M. Wood, David Elliot, Ken Page, Attilla Ting, Paul T. Sharpe
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:4832-4835
مصطلحات موضوعية: biology, Cell adhesion molecule, medicine.drug_class, Chemistry, Organic Chemistry, Clinical Biochemistry, Integrin, Pharmaceutical Science, Carboxamide, Biochemistry, In vitro, embryonic structures, Drug Discovery, cardiovascular system, medicine, biology.protein, Molecular Medicine, Structure–activity relationship, Potency, Binding site, Arginine binding, Molecular Biology
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5
المؤلفون: Neil Rankine, Andrea M. Bamford, Daniel S. James, Vanessa Torr, Brown George Robert, Jonathan Bowyer, Eric J. Culbert, Eric Tang
المصدر: Bioorganic & Medicinal Chemistry Letters. 10:575-579
مصطلحات موضوعية: Ketone, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Enzyme-Linked Immunosorbent Assay, Naphthalenes, Biochemistry, Chemical synthesis, Aminoketone, Mannich Bases, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Structure–activity relationship, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, biology, Janus kinase 3, Organic Chemistry, Janus Kinase 3, Ketones, Protein-Tyrosine Kinases, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Indicators and Reagents, Enone, Tyrosine kinase
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6
المؤلفون: Jonathan Bowyer, Vanessa Torr, Daniel S. James, Neil Rankine, Eric Tang, Brown George Robert, Andrea M. Bamford, Eric J. Culbert
المصدر: ChemInform. 31
مصطلحات موضوعية: chemistry.chemical_classification, Ketone, chemistry, Stereochemistry, Janus kinase 3, General Medicine, Janus, Elisa assay, Tyrosine kinase, In vitro
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7
المؤلفون: David, Elliot, Eleanor, Henshaw, Philip A, MacFaul, Andrew D, Morley, Peter, Newham, Keith, Oldham, Ken, Page, Neil, Rankine, Paul, Sharpe, Attilla, Ting, Christine M, Wood
المصدر: Bioorganicmedicinal chemistry letters. 19(16)
مصطلحات موضوعية: Small Molecule Libraries, Structure-Activity Relationship, Binding Sites, Drug Design, Animals, Humans, Computer Simulation, Integrin alphaVbeta3, Oligopeptides, Rats