المؤلفون: Zhuang X; 1] School of Immunity and Infection, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK [2] School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK., Herbert JM; 1] School of Immunity and Infection, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK [2] Technology Hub Sequencing and Bioinformatics, College of Medical and Dental Sciences, Birmingham B15, UK., Lodhia P; School of Immunity and Infection, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK., Bradford J; AstraZeneca, Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Turner AM; 1] School of Clinical and Experimental Medicine, University of Birmingham, QEHB Research Laboratories, Mindelsohn Way, Birmingham B15 2WB, UK [2] Birmingham Heartlands Hospital, Bordesley Green, Birmingham B9 5SS, UK., Newby PM; School of Immunity and Infection, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK., Thickett D; School of Clinical and Experimental Medicine, University of Birmingham, QEHB Research Laboratories, Mindelsohn Way, Birmingham B15 2WB, UK., Naidu U; 1] School of Clinical and Experimental Medicine, University of Birmingham, QEHB Research Laboratories, Mindelsohn Way, Birmingham B15 2WB, UK [2] Birmingham Heartlands Hospital, Bordesley Green, Birmingham B9 5SS, UK., Blakey D; AstraZeneca, Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Barry S; AstraZeneca, Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Cross DA; AstraZeneca, Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK., Bicknell R; 1] School of Immunity and Infection, Institute for Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK [2] School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

المصدر: British journal of cancer [Br J Cancer] 2015 Feb 03; Vol. 112 (3), pp. 485-94. Date of Electronic Publication: 2014 Dec 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Targeted Therapy*, Carcinoma, Non-Small-Cell Lung/*blood supply , Carcinoma, Non-Small-Cell Lung/*genetics , Lung Neoplasms/*blood supply , Lung Neoplasms/*genetics , Neovascularization, Pathologic/*genetics, Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/pathology ; Female ; Gene Expression Profiling ; Genetic Association Studies/methods ; Humans ; Lung/blood supply ; Lung/metabolism ; Lung/pathology ; Lung Neoplasms/drug therapy ; Male ; Microarray Analysis ; Middle Aged ; Neovascularization, Pathologic/drug therapy ; Real-Time Polymerase Chain Reaction ; Sequence Analysis, RNA