نتائج البحث - "Nichole Coleman"

المساهمون: National Institute of Neurological Disorders and Stroke (US), Ministerio de Economía y Competitividad (España), Instituto de Salud Carlos III, Gobierno de Aragón, Danish Heart Foundation, European Commission, German Research Foundation

المصدر: Oliván-Viguera, A, Valero, M S, Pinilla, E, Amor, S, García-Villalón, Á L, Coleman, N, Laría, C, Calvín-Tienza, V, García-Otín, Á-L, Fernández-Fernández, J M, Murillo, M D, Gálvez, J A, Díaz-de-Villegas, M D, Badorrey, R, Simonsen, U, Rivera, L, Wulff, H & Köhler, R 2016, ' Vascular reactivity profile of novel KC a 3.1-selective positive-gating modulators in the coronary vascular bed ', Basic & Clinical Pharmacology & Toxicology, vol. 119, no. 2, pp. 184-92 . https://doi.org/10.1111/bcpt.12560
Oliván-Viguera, A; Valero, MS; Pinilla, E; Amor, S; García-Villalón, ÁL; Coleman, N; et al.(2016). Vascular Reactivity Profile of Novel KCa3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed. Basic and Clinical Pharmacology and Toxicology, 119(2), 184-192. doi: 10.1111/bcpt.12560. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/79p117fm
Digital.CSIC. Repositorio Institucional del CSIC
instname
Basic & clinical pharmacology & toxicology, vol 119, iss 2
R-USJ: Repositorio Institucional de la Universidad San Jorge
Universidad San Jorge (USJ)

مصطلحات موضوعية: Male, 0301 basic medicine, Patch-Clamp Techniques, Swine, Vasodilator Agents, Messenger, Vasodilation, 030204 cardiovascular system & hematology, Pharmacology, Cardiovascular, Toxicology, Rats, Sprague-Dawley, 0302 clinical medicine, Pharmacology & Pharmacy, Endothelial dysfunction, Oxazoles, Cells, Cultured, Membrane potential, Cultured, Heart, Pharmacology and Pharmaceutical Sciences, General Medicine, Hyperpolarization (biology), Intermediate-Conductance Calcium-Activated Potassium Channels, Coronary Vessels, Potassium channel, 3. Good health, Heart Disease, medicine.anatomical_structure, Nitric Oxide Synthase Type III, Cells, Bradykinin, Article, 03 medical and health sciences, Coronary circulation, Vascular, Coronary Circulation, medicine, Animals, Endothelium, RNA, Messenger, Patch clamp, business.industry, Endothelial Cells, Membrane hyperpolarization, medicine.disease, Rats, 030104 developmental biology, Gene Expression Regulation, RNA, Pyrazoles, KCa3.1, Sprague-Dawley, Endothelium, Vascular, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ec50c019e846880bc52178cda3e572
https://pure.au.dk/portal/da/publications/vascular-reactivity-profile-of-novel-kc-a-31selective-positivegating-modulators-in-the-coronary-vascular-bed(263cb911-53a5-49e9-a16d-8de7747e950a).html

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The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant

المؤلفون: Heike Wulff, Isaac N. Pessah, Brandon M. Brown, Hai M. Nguyen, Zhengyu Cao, Nichole Coleman, Alan L. Goldin, Yi-Je Chen, Brian S. Tanaka, David Paul Jenkins, Dorota Zolkowska, Michael A. Rogawski

المصدر: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, vol 12, iss 1
Neurotherapeutics, vol 12, iss 1
Coleman, N; Nguyen, HM; Cao, Z; Brown, BM; Jenkins, DP; Zolkowska, D; et al.(2014). The Riluzole Derivative 2-Amino-6-trifluoromethylthio-benzothiazole (SKA-19), a Mixed KCa2 Activator and NaV Blocker, is a Potent Novel Anticonvulsant. Neurotherapeutics. doi: 10.1007/s13311-014-0305-y. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2df5806k

مصطلحات موضوعية: Male, medicine.medical_treatment, Voltage-Gated Sodium Channels, Pharmacology, Neurodegenerative, Rats, Sprague-Dawley, Mice, Oral administration, Anticonvulsant, Afterhyperpolarization, Pharmacology (medical), ED50, Riluzole, Chemistry, Pain Research, Pharmacology and Pharmaceutical Sciences, 5.1 Pharmaceuticals, Neurological, Public Health and Health Services, Original Article, Anticonvulsants, Chronic Pain, Development of treatments and therapeutic interventions, medicine.drug, Pain Threshold, Analgesic, Pain Conditions - Chronic, Calcium-activated potassium channel, Seizures, medicine, Voltage-gated sodium channel, Animals, Epilepsy, Neurology & Neurosurgery, Animal, Sodium channel, Neurosciences, Rats, Brain Disorders, Disease Models, Animal, Disease Models, Seizure models, Neurology (clinical), Sprague-Dawley

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6b673de12a5d613a6b10f3680ace34
https://escholarship.org/uc/item/2df5806k

5

Positive KCa channel gating modulators with selectivity for KCa3.1 (1057.6)

المؤلفون: Heike Wulff, Nichole Coleman, Aida Oliván-Viguera, Brandon M. Brown, Ralf Köhler

المصدر: The FASEB Journal. 28

مصطلحات موضوعية: Calmodulin, biology, Calmodulin binding domain, Gating, Biochemistry, Cell biology, chemistry.chemical_compound, Benzothiazole, chemistry, Genetics, biology.protein, Potency, Ca2 channels, Selectivity, Membrane excitability, Molecular Biology, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4910a1b4c5b4c36423a8285b4624ea74
https://doi.org/10.1096/fasebj.28.1_supplement.1057.6

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6

The therapeutic potential of small-conductance KCa2 channels in neurodegenerative and psychiatric diseases

المؤلفون: Heike Wulff, April L. Garing, Jenny Lam, Nichole Coleman

المصدر: Lam, J; Coleman, N; Garing, ALA; & Wulff, H. (2013). The therapeutic potential of small-conductance KCa2 channels in neurodegenerative and psychiatric diseases. Expert Opinion on Therapeutic Targets, 17(10), 1203-1220. doi: 10.1517/14728222.2013.823161. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/4zp6694g
Expert opinion on therapeutic targets, vol 17, iss 10

مصطلحات موضوعية: Parkinson's disease, Small-Conductance Calcium-Activated Potassium Channels, Clinical Biochemistry, small-conductance, Neurodegenerative, chemistry.chemical_compound, Alcohol Use and Health, Substance Misuse, Drug Discovery, 2.1 Biological and endogenous factors, Aetiology, Mental Disorders, NS13001, KCa2, Afterhyperpolarization, Neurodegenerative Diseases, Pharmacology and Pharmaceutical Sciences, Alzheimer's disease, alcohol dependence and withdrawal, riluzole, Riluzole, Alcoholism, medicine.anatomical_structure, SKA-31, Neurological, Molecular Medicine, Mental health, medicine.symptom, learning and memory, medicine.drug, medicine.medical_specialty, Ataxia, Artificial Intelligence and Image Processing, Central nervous system, Apamin, Article, calcium-activated potassium channel, Membrane Transport Modulators, medicine, Genetics, Animals, Humans, Oncology & Carcinogenesis, Psychiatry, Pharmacology, Episodic ataxia, Cerebellar ataxia, business.industry, ataxia, Neurosciences, medicine.disease, Brain Disorders, schizophrenia, NS309, Good Health and Well Being, chemistry, business, apamin, EBIO, afterhyperpolarization

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e7141030cbab6179509f9911390ab81
http://www.escholarship.org/uc/item/4zp6694g

7

Triarylmethanes, a new class of cx50 inhibitors

المؤلفون: Miduturu Srinivas, Maria Pilar Trelles, David Paul Jenkins, Clio Rubinos, Silke B. Bodendiek, Nichole Coleman, Heike Wulff

المصدر: Frontiers in Pharmacology, Vol 3 (2012)
Frontiers in Pharmacology

مصطلحات موضوعية: Structure-activity-relationship, lens, channel, Connexin, Pharmacology, Inhibitory postsynaptic potential, 03 medical and health sciences, 0302 clinical medicine, inhibitors, medicine, Structure–activity relationship, Pharmacology (medical), Ion channel, gap junctions, Original Research, 030304 developmental biology, 0303 health sciences, lens epithelial cells, pharmacophore, Chemistry, lcsh:RM1-950, Gap junction, Gap Junctions, triarylmethane, Pharmacology and Pharmaceutical Sciences, 3. Good health, medicine.anatomical_structure, lcsh:Therapeutics. Pharmacology, connexin 50, 5.1 Pharmaceuticals, Lens (anatomy), ion channel, Biophysics, sense organs, Pharmacophore, Development of treatments and therapeutic interventions, Selectivity, 030217 neurology & neurosurgery, SAR

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f75a4859cc4f9f671bef4d9ac6b499
https://escholarship.org/uc/item/5588p10b

8

Positive KCa Channel Gating Modulators with Selectivity for KCa3.1

المؤلفون: Brandon M. Brown, Heike Wulff, Vladimir Yarov-Yarovoy, Nichole Coleman

المصدر: Brown, BM; Coleman, N; Yarov-Yarovoy, V; & Wulff, H. (2015). Positive KCa Channel Gating Modulators with Selectivity for KCa3.1. BIOPHYSICAL JOURNAL, 108(2), 20A-20A. doi: 10.1016/j.bpj.2014.11.134. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/0kx2n0d2
Biophysical Journal, vol 108, iss 2
BIOPHYSICAL JOURNAL, vol 108, iss 2

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6c8a78909f618029778a9f797624a8
https://doi.org/10.1016/j.bpj.2014.11.134

View record from ScienceDirect

9

SKA-111, a Positive KCa Channel Gating Modulator with Selectivity for KCa3.1

المؤلفون: Ralf Köhler, Paul David Jenkins, Heike Wulff, Brandon M. Brown, Nichole Coleman

المصدر: Biophysical Journal. 106:642a

مصطلحات موضوعية: Calmodulin, biology, Endothelium, Calmodulin binding domain, Biophysics, Gating, Pharmacology, Biochemistry, chemistry.chemical_compound, medicine.anatomical_structure, Benzothiazole, chemistry, In vivo, Genetics, biology.protein, medicine, Structure–activity relationship, Ca2 channels, Pharmacophore, Selectivity, Molecular Biology, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2cfe6bdf6b5362019955ace692f7963
https://doi.org/10.1016/j.bpj.2013.11.3556

View record from ScienceDirect

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