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المؤلفون: JC Liu, Lauren Kalinowski, QC Xu, M Bettington, Stephen B. Fox, JM Saunus, Puay Hoon Tan, E Kalaw, Kate J. Johnstone, Sunil R. Lakhani, Sandra A O'Toole, Katia Nones, A.E. McCart Reed, Kaltin Ferguson, Gary Tse, Irma Gresshoff, Colleen Niland, Peter T. Simpson, Rin Yamaguchi, David Papadimos, Stephen H. Kazakoff, LE Reid, Nick Waddell, Jamie R. Kutasovic, Gavin Harris, D Black, James Bennett, Andrew Scott Reid, Morgan R. Davidson, Rajadurai Pathmanathan, John V. Pearson, Malcolm Lim, Nirmala Pathmanathan, Ashwini Raghavendra
المصدر: Cancer Research. 79:P3-08
مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, biology, CD44, Cancer, medicine.disease, Breast cancer, Internal medicine, Cohort, biology.protein, medicine, PTEN, Stage (cooking), Survival rate, Exome sequencing
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e8f555c7b2b84c06eafb0a764a1282bd
https://doi.org/10.1158/1538-7445.sabcs18-p3-08-03 -
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المؤلفون: Heather Thorne, A-M Patch, John F. Pearson, F Newell, Georgia Chenevix-Trench, Sriganesh Srihari, Vanessa Lakis, Katia Nones, Conrad Leonard, Sunil R. Lakhani, J Beasley, Peter T. Simpson, Michael T. Parsons, Mark A. Ragan, Aimee L Davidson, Amanda B. Spurdle, Andrea Degasperi, K. K. Khanna, Oliver Holmes, Julie K. Johnson, Kaltin Ferguson, Stephen H. Kazakoff, Serena Nik-Zainal, Scott Wood, Nick Waddell, Pamela Mukhopadhyay, Qinying Xu, X. M. De Luca, A.E. McCart Reed, Lynne Reid
المصدر: Cancer Research. 79:P5-10
مصطلحات موضوعية: Genetics, Whole genome sequencing, Cancer Research, Mutation, endocrine system diseases, PALB2, Cancer, Single-nucleotide polymorphism, Biology, medicine.disease, medicine.disease_cause, Germline mutation, Breast cancer, Oncology, medicine, skin and connective tissue diseases, CHEK2
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::317682359e8da6428f3291f702dbfddd
https://doi.org/10.1158/1538-7445.sabcs18-p5-10-01 -
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المؤلفون: Stephan B. Dreyer, Rosie Upstill-Goddard, Viola Paulus-Hock, Clara Paris, Eirini-Maria Lampraki, Eloise Dray, Bryan Serrels, Giuseppina Caligiuri, Selma Rebus, Dennis Plenker, Zachary Galluzzo, Holly Brunton, Richard Cunningham, Mathias Tesson, Craig Nourse, Ulla-Maja Bailey, Marc Jones, Kim Moran-Jones, Derek W. Wright, Fraser Duthie, Karin Oien, Lisa Evers, Colin J. McKay, Grant A. McGregor, Aditi Gulati, Rachel Brough, Ilirjana Bajrami, Stephan Pettitt, Michele L. Dziubinski, Juliana Candido, Frances Balkwill, Simon T. Barry, Robert Grützmann, Lola Rahib, Amber Johns, Marina Pajic, Fieke E.M. Froeling, Phillip Beer, Elizabeth A. Musgrove, Gloria M. Petersen, Alan Ashworth, Margaret C. Frame, Howard C. Crawford, Diane M. Simeone, Chris Lord, Debabrata Mukhopadhyay, Christian Pilarsky, David A. Tuveson, Susanna L. Cooke, Nigel B. Jamieson, Jennifer P. Morton, Owen J. Sansom, Peter J. Bailey, Andrew V. Biankin, David K. Chang, Sarah Allison, Dario Beraldi, Euan Cameron, Stephan Dreyer, Paul Grimwood, Shane Kelly, John Marshall, Sancha Martin, Brian McDade, Daniel McElroy, Donna Ramsay, Derek Wright, Marc D. Jones, Jane Hair, Paul Westwood, Nicola Williams, Amber L. Johns, Amanda Mawson, Christopher J. Scarlett, Mary-Anne L. Brancato, Sarah J. Rowe, Skye H. Simpson, Mona Martyn-Smith, Michelle T. Thomas, Lorraine A. Chantrill, Venessa T. Chin, Angela Chou, Mark J. Cowley, Jeremy L. Humphris, R. Scott Mead, Adnan M. Nagrial, Jessica Pettit, Mark Pinese, Ilse Rooman, Jianmin Wu, Jiang Tao, Renee DiPietro, Clare Watson, Angela Steinmann, Hong Ching Lee, Rachel Wong, Andreia V. Pinho, Marc Giry-Laterriere, Roger J. Daly, Robert L. Sutherland, Sean M. Grimmond, Nicola Waddell, Karin S. Kassahn, David K. Miller, Peter J. Wilson, Ann-Marie Patch, Sarah Song, Ivon Harliwong, Senel Idrisoglu, Ehsan Nourbakhsh, Suzanne Manning, Shivangi Wani, Milena Gongora, Matthew Anderson, Oliver Holmes, Conrad Leonard, Darrin Taylor, Scott Wood, Christina Xu, Katia Nones, J. Lynn Fink, Angelika Christ, Tim Bruxner, Nicole Cloonan, Felicity Newell, John V. Pearson, Peter Bailey, Michael Quinn, Shivashankar Nagaraj, Stephen Kazakoff, Nick Waddell, Keerthana Krisnan, Kelly Quek, David Wood, Jaswinder S. Samra, Anthony J. Gill, Nick Pavlakis, Alex Guminski, Christopher Toon, Ray Asghari, Neil D. Merrett, Darren Pavey, Amitabha Das, Peter H. Cosman, Kasim Ismail, Chelsie O’Connnor, Vincent W. Lam, Duncan McLeod, Henry C. Pleass, Arthur Richardson, Virginia James, James G. Kench, Caroline L. Cooper, David Joseph, Charbel Sandroussi, Michael Crawford, James Gallagher, Michael Texler, Cindy Forest, Andrew Laycock, Krishna P. Epari, Mo Ballal, David R. Fletcher, Sanjay Mukhedkar, Nigel A. Spry, Bastiaan DeBoer, Ming Chai, Nikolajs Zeps, Maria Beilin, Kynan Feeney, Nan Q. Nguyen, Andrew R. Ruszkiewicz, Chris Worthley, Chuan P. Tan, Tamara Debrencini, John Chen, Mark E. Brooke-Smith, Virginia Papangelis, Henry Tang, Andrew P. Barbour, Andrew D. Clouston, Patrick Martin, Thomas J. O’Rourke, Amy Chiang, Jonathan W. Fawcett, Kellee Slater, Shinn Yeung, Michael Hatzifotis, Peter Hodgkinson, Christopher Christophi, Mehrdad Nikfarjam, Angela Mountain, Victorian Cancer Biobank, James R. Eshleman, Ralph H. Hruban, Anirban Maitra, Christine A. Iacobuzio-Donahue, Richard D. Schulick, Christopher L. Wolfgang, Richard A. Morgan, Mary Hodgin, Aldo Scarpa, Rita T. Lawlor, Stefania Beghelli, Vincenzo Corbo, Maria Scardoni, Claudio Bassi, Margaret A. Tempero, Janet S. Graham
المساهمون: Basic (bio-) Medical Sciences
المصدر: Dreyer, S B, Upstill-goddard, R, Paulus-hock, V, Paris, C, Lampraki, E, Dray, E, Serrels, B, Caligiuri, G, Rebus, S, Plenker, D, Galluzzo, Z, Brunton, H, Cunningham, R, Tesson, M, Nourse, C, Bailey, U, Jones, M, Moran-jones, K, Wright, D W, Duthie, F, Oien, K, Evers, L, Mckay, C J, Mcgregor, G A, Gulati, A, Brough, R, Bajrami, I, Pettitt, S, Dziubinski, M L, Candido, J, Balkwill, F, Barry, S T, Grützmann, R, Rahib, L, Johns, A, Pajic, M, Froeling, F E M, Beer, P, Musgrove, E A, Petersen, G M, Ashworth, A, Frame, M C, Crawford, H C, Simeone, D M, Lord, C, Mukhopadhyay, D, Pilarsky, C, Tuveson, D A, Cooke, S L, Jamieson, N B, Morton, J P, Sansom, O J, Bailey, P J, Biankin, A V, Chang, D K, Allison, S, Bailey, P J, Bailey, U, Biankin, A V, Beraldi, D, Brunton, H, Caligiuri, G, Cameron, E, Chang, D K, Cooke, S L, Cunningham, R, Dreyer, S, Grimwood, P, Kelly, S, Lampraki, E, Marshall, J, Martin, S, Mcdade, B, Mcelroy, D, Musgrove, E A, Nourse, C, Paulus-hock, V, Ramsay, D, Upstill-goddard, R, Wright, D W, Jones, M D, Evers, L, Rebus, S, Rahib, L, Serrels, B, Hair, J, Jamieson, N B, Mckay, C J, Westwood, P, Williams, N, Duthie, F, Biankin, A V, Johns, A L, Mawson, A, Chang, D K, Scarlett, C J, Brancato, M L, Rowe, S J, Simpson, S H, Martyn-smith, M, Thomas, M T, Chantrill, L A, Chin, V T, Chou, A, Cowley, M J, Humphris, J L, Jones, M D, Mead, R S, Nagrial, A M, Pajic, M, Pettit, J, Pinese, M, Rooman, I, Wu, J, Tao, J, Dipietro, R, Watson, C, Steinmann, A, Lee, H C, Wong, R, Pinho, A V, Giry-laterriere, M, Daly, R J, Musgrove, E A, Sutherland, R L, Grimmond, S M, Waddell, N, Kassahn, K S, Miller, D K, Wilson, P J, Patch, A, Song, S, Harliwong, I, Idrisoglu, S, Nourse, C, Nourbakhsh, E, Manning, S, Wani, S, Gongora, M, Anderson, M, Holmes, O, Leonard, C, Taylor, D, Wood, S, Xu, C, Nones, K, Fink, J L, Christ, A, Bruxner, T, Cloonan, N, Newell, F, Pearson, J V, Bailey, P, Quinn, M, Nagaraj, S, Kazakoff, S, Waddell, N, Krisnan, K, Quek, K, Wood, D, Samra, J S, Gill, A J, Pavlakis, N, Guminski, A, Toon, C, Asghari, R, Merrett, N D, Pavey, D, Das, A, Cosman, P H, Ismail, K, O’connnor, C, Lam, V W, Mcleod, D, Pleass, H C, Richardson, A, James, V, Kench, J G, Cooper, C L, Joseph, D, Sandroussi, C, Crawford, M, Gallagher, J, Texler, M, Forest, C, Laycock, A, Epari, K P, Ballal, M, Fletcher, D R, Mukhedkar, S, Spry, N A, Deboer, B, Chai, M, Zeps, N, Beilin, M, Feeney, K, Nguyen, N Q, Ruszkiewicz, A R, Worthley, C, Tan, C P, Debrencini, T, Chen, J, Brooke-smith, M E, Papangelis, V, Tang, H, Barbour, A P, Clouston, A D, Martin, P, O’rourke, T J, Chiang, A, Fawcett, J W, Slater, K, Yeung, S, Hatzifotis, M, Hodgkinson, P, Christophi, C, Nikfarjam, M, Mountain, A, Biobank, V C, Eshleman, J R, Hruban, R H, Maitra, A, Iacobuzio-donahue, C A, Schulick, R D, Wolfgang, C L, Morgan, R A, Hodgin, M, Scarpa, A, Lawlor, R T, Beghelli, S, Corbo, V, Scardoni, M, Bassi, C, Tempero, M A, Biankin, A V, Grimmond, S M, Chang, D K, Musgrove, E A, Jones, M D, Nourse, C, Jamieson, N B, Graham, J S, Biankin, A V, Chang, D K, Jamieson, N B & Graham, J S 2020, ' Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer ', Gastroenterology, vol. 160, no. 1, pp. 362-377.e13 . https://doi.org/10.1053/j.gastro.2020.09.043
Gastroenterologyمصطلحات موضوعية: 0301 basic medicine, HRD, homologous recombination deficiency, DNA Repair, PDAC, pancreatic ductal adenocarcinoma, Cell Culture Techniques, DMSO, dimethyl sulfoxide, Transcriptome, 0302 clinical medicine, Molecular Targeted Therapy, SV, structural variation, Original Research, Cancer, PDCL, patient-derived cell line, Gastroenterology, Organoids, PC, pancreatic cancer, oncology, PARP inhibitor, RNAseq, RNA sequencing, 030211 gastroenterology & hepatology, DNA Damage Response, ICGC, International Cancer Genome Consortium, DNA Replication, DNA repair, DNA damage, RPPA, reverse-phase protein array, EC50, median effective concentration, MTS, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, Adenocarcinoma, Biology, DDR, DNA damage response, TOM, topological overlap measure, 03 medical and health sciences, Pancreatic Cancer, Cell Line, Tumor, Pancreatic cancer, GO, Gene Ontology, medicine, Humans, PDX, patient-derived xenograft, Hepatology, DNA replication, Personalized Medicine, Replication Stress, medicine.disease, Xenograft Model Antitumor Assays, Pancreatic Neoplasms, body regions, 030104 developmental biology, siRNA, small interfering RNA, Cancer research, Full Report: Basic and Translational—Pancreas, HR, homologous recombination, Homologous recombination, Biomarkers, DNA Damage
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a3f9673fbfb1bdd5184962a42fdfee
http://hdl.handle.net/11562/1045585 -
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المؤلفون: Holly Brunton, Giuseppina Caligiuri, Richard Cunningham, Rosie Upstill-Goddard, Ulla-Maja Bailey, Ian M. Garner, Craig Nourse, Stephan Dreyer, Marc Jones, Kim Moran-Jones, Derek W. Wright, Viola Paulus-Hock, Colin Nixon, Gemma Thomson, Nigel B. Jamieson, Grant A. McGregor, Lisa Evers, Colin J. McKay, Aditi Gulati, Rachel Brough, Ilirjana Bajrami, Stephen J. Pettitt, Michele L. Dziubinski, Simon T. Barry, Robert Grützmann, Robert Brown, Edward Curry, Marina Pajic, Elizabeth A. Musgrove, Gloria M. Petersen, Emma Shanks, Alan Ashworth, Howard C. Crawford, Diane M. Simeone, Fieke E.M. Froeling, Christopher J. Lord, Debabrata Mukhopadhyay, Christian Pilarsky, Sean E. Grimmond, Jennifer P. Morton, Owen J. Sansom, David K. Chang, Peter J. Bailey, Andrew V. Biankin, Sarah Allison, Susanna L. Cooke, Paul Grimwood, Shane Kelly, John Marshall, Brian McDade, Daniel McElroy, Donna Ramsay, Selma Rebus, Jane Hair, Paul Westwood, Nicola Williams, Fraser Duthie, Amber L. Johns, Amanda Mawson, Christopher J. Scarlett, Mary-Anne L. Brancato, Sarah J. Rowe, Skye H. Simpson, Mona Martyn-Smith, Michelle T. Thomas, Lorraine A. Chantrill, Venessa T. Chin, Angela Chou, Mark J. Cowley, Jeremy L. Humphris, R. Scott Mead, Adnan M. Nagrial, Jessica Pettit, Mark Pinese, Ilse Rooman, Jianmin Wu, Jiang Tao, Renee DiPietro, Clare Watson, Angela Steinmann, Hong Ching Lee, Rachel Wong, Andreia V. Pinho, Marc Giry-Laterriere, Roger J. Daly, Robert L. Sutherland, Sean M. Grimmond, Nicola Waddell, Karin S. Kassahn, David K. Miller, Peter J. Wilson, Ann-Marie Patch, Sarah Song, Ivon Harliwong, Senel Idrisoglu, Ehsan Nourbakhsh, Suzanne Manning, Shivangi Wani, Milena Gongora, Matthew Anderson, Oliver Holmes, Conrad Leonard, Darrin Taylor, Scott Wood, Christina Xu, Katia Nones, J. Lynn Fink, Angelika Christ, Tim Bruxner, Nicole Cloonan, Felicity Newell, John V. Pearson, Michael Quinn, Shivashankar Nagaraj, Stephen Kazakoff, Nick Waddell, Keerthana Krisnan, Kelly Quek, David Wood, Jaswinder S. Samra, Anthony J. Gill, Nick Pavlakis, Alex Guminski, Christopher Toon, Ray Asghari, Neil D. Merrett, Darren Pavey, Amitabha Das, Peter H. Cosman, Kasim Ismail, Chelsie O’Connnor, Vincent W. Lam, Duncan McLeod, Henry C. Pleass, Arthur Richardson, Virginia James, James G. Kench, Caroline L. Cooper, David Joseph, Charbel Sandroussi, Michael Crawford, James Gallagher, Michael Texler, Cindy Forest, Andrew Laycock, Krishna P. Epari, Mo Ballal, David R. Fletcher, Sanjay Mukhedkar, Nigel A. Spry, Bastiaan DeBoer, Ming Chai, Nikolajs Zeps, Maria Beilin, Kynan Feeney, Nan Q. Nguyen, Andrew R. Ruszkiewicz, Chris Worthley, Chuan P. Tan, Tamara Debrencini, John Chen, Mark E. Brooke-Smith, Virginia Papangelis, Henry Tang, Andrew P. Barbour, Andrew D. Clouston, Patrick Martin, Thomas J. O’Rourke, Amy Chiang, Jonathan W. Fawcett, Kellee Slater, Shinn Yeung, Michael Hatzifotis, Peter Hodgkinson, Christopher Christophi, Mehrdad Nikfarjam, Angela Mountain, James R. Eshleman, Ralph H. Hruban, Anirban Maitra, Christine A. Iacobuzio-Donahue, Richard D. Schulick, Christopher L. Wolfgang, Richard A. Morgan, Mary Hodgin, Aldo Scarpa, Rita T. Lawlor, Stefania Beghelli, Vincenzo Corbo, Maria Scardoni, Claudio Bassi, Margaret A. Tempero, Janet S. Graham
المساهمون: Basic (bio-) Medical Sciences
مصطلحات موضوعية: 0301 basic medicine, Biology, Adenocarcinoma, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, GATA6, GSK-3, Pancreatic cancer, Cell Line, Tumor, GATA6 Transcription Factor, medicine, Biomarkers, Tumor, Humans, GSK3B, chromatin landscapes, metabolic targeting, intronic and distal promoters, medicine.disease, Phenotype, HNF4A, Chromatin, 030104 developmental biology, Hepatocyte nuclear factor 4, Hepatocyte Nuclear Factor 4, PDAC subtypes, oncology, Cancer research, therapeutic tolerance, 030217 neurology & neurosurgery, Carcinoma, Pancreatic Ductal
وصف الملف: application/pdf
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المؤلفون: Anna Fitzgerald, John V. Pearson, Andrew J. Spillane, Loretta Lau, Nuria Lopez-Bigas, Peter Johansson, Catherine A. Shang, Richard A. Scolyer, John F. Thompson, Scott Wood, Valerie Jakrot, Peter Hersey, Katia Nones, Rebecca A. Dagg, Antonia L. Pritchard, Conrad Leonard, Andreas Behren, Varsha Tembe, Robyn P. M. Saw, Loris Mularoni, Nick Waddell, Mark Shackleton, Hojabr Kakavand, Ping Shang, Jean Y. Yang, Graham J. Mann, Radhakrishnan Sabarinathan, Gulietta M. Pupo, Ricardo De Paoli-Iseppi, Jonathan Cebon, Richard F. Kefford, Ricardo E. Vilain, Hilda A. Pickett, Stephen H. Kazakoff, Ludmil B. Alexandrov, Oliver Holmes, Nicholas K. Hayward, Nicola Waddell, Ken Dutton-Regester, Jonathan R. Stretch, Sean M. Grimmond, Felicity Newell, Qinying Xu, James S. Wilmott, Hazel Burke, Georgina V. Long, Sarah-Jane Schramm, Matthew A. Field, Ann-Marie Patch
المصدر: Nature
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelonaمصطلحات موضوعية: Proto-Oncogene Proteins B-raf, 0301 basic medicine, Neuroblastoma RAS viral oncogene homolog, X-linked Nuclear Protein, Neurofibromatosis 1, Ultraviolet Rays, Biology, medicine.disease_cause, GTP Phosphohydrolases, 03 medical and health sciences, 0302 clinical medicine, CDKN2A, medicine, Humans, Càncer, skin and connective tissue diseases, Melanoma, Telomerase, neoplasms, ATRX, Cancer, Genetics, Mutation, Multidisciplinary, Genome, Human, Genes, p16, DNA Helicases, Mucosal melanoma, Membrane Proteins, Nuclear Proteins, Telomere, Phosphoproteins, medicine.disease, 3. Good health, 030104 developmental biology, 030220 oncology & carcinogenesis, Cutaneous melanoma, Cancer research, RNA Splicing Factors, Mitogen-Activated Protein Kinases, Tumor Suppressor Protein p53, Signal Transduction
وصف الملف: application/pdf
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المؤلفون: Ana Cristina Vargas, L. da Silva, Peter T. Simpson, Katia Nones, Sunil R. Lakhani, MM Cummings, Janani Jayanthan, Alan Porter, Jamie R. Kutasovic, Lewis Melville, Jodi M. Saunus, A.E. McCart Reed, Elizabeth Evans, Lynne Reid, Nick Waddell
المصدر: Cancer Research. 77:P1-07
مصطلحات موضوعية: Cancer Research, Pathology, medicine.medical_specialty, Lobular carcinoma, Clone (cell biology), Cancer, Ductal carcinoma, Biology, medicine.disease, Somatic evolution in cancer, Phenotype, CDH1, Breast cancer, Oncology, medicine, biology.protein, skin and connective tissue diseases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fa545e9de06d3d43a7315c006881e7b7
https://doi.org/10.1158/1538-7445.sabcs16-p1-07-08 -
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المؤلفون: Mythily Mariasegaram, Ann-Marie Patch, Conrad Leonard, Admire Matsika, Sean M. Grimmond, Fares Al-Ejeh, Margaret C. Cummings, Rosalind L. Jeffree, Georgia Chenevix-Trench, Oliver Holmes, Leonard Da Silva, Nur Aishah Taib, Adrienne M. Flanagan, Teresa K. Withers, Matthew J. Anderson, Vairavan Narayanan, Ehsan Nourbakhsh, Queenie Lau, Sunil R. Lakhani, J. Lynn Fink, kConFab, Felicity Newell, Katia Nones, Stephen H. Kazakoff, Colleen Niland, Parmjit S. Jat, Ivon Harliwong, Peter T. Simpson, Lynne Reid, Nicola Waddell, Soo Hwang Teo, Karin S. Kassahn, Sebastian Brandner, John V. Pearson, Nick Waddell, Qinying Xu, Scott Wood, Darrin Taylor, Senel Idrisoglu, Peter Wilson, Timothy J. C. Bruxner, Kum Kum Khanna, Craig Nourse, Shivangi Wani, Angelika N. Christ, David Miller, Amy E. McCart Reed, Michael C.J. Quinn, Yock Ping Chow, Jodi M. Saunus, Suzanne Manning, Peter Bailey
المصدر: The Journal of Pathology. 237:363-378
مصطلحات موضوعية: medicine.medical_treatment, Cancer, Genomic signature, Biology, medicine.disease, Bioinformatics, Pathology and Forensic Medicine, Targeted therapy, Gene expression profiling, Breast cancer, ErbB, medicine, Cancer research, skin and connective tissue diseases, Exome, Brain metastasis
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المؤلفون: Borislav Rusev, Krishna Epari, Peter Bailey, Christopher J. Scarlett, Suzanne Manning, Marina Pajic, Conrad Leonard, Skye McKay, Michael C.J. Quinn, Oliver Hofmann, Margaret A. Tempero, Anthony J. Gill, Nikolajs Zeps, Marc Giry-Laterriere, James G. Kench, Christian Pilarsky, Karin A. Oien, Christine A. Iacobuzio-Donahue, Jennifer P. Morton, Janet Graham, Ilse Rooman, Ehsan Nourbakhsh, Euan J. Dickson, Felicity Newell, Ann-Marie Patch, Sean M. Grimmond, Amber L. Johns, Mark J. Cowley, Timothy J. C. Bruxner, C. Ross Carter, Ivana Cataldo, Rita T. Lawlor, Andrew V. Biankin, David K. Chang, Peter J. Wilson, Christopher L. Wolfgang, Mark Pinese, Roberto Salvia, Karin S. Kassahn, Ralph H. Hruban, Richard D. Schulick, Adnan Nagrial, David Miller, Elizabeth A. Musgrove, Venessa T. Chin, Owen J. Sansom, Ronald S Mead, Angela Chou, Nam Q. Nguyen, J. Lynn Fink, Katia Nones, Craig Nourse, Robert Grützmann, Andreia V. Pinho, Lorraine A. Chantrill, Matthew J. Anderson, Nigel B. Jamieson, Fraser Duthie, Qinying Xu, Stephen H. Kazakoff, Jianmin Wu, Nicola Waddell, Amanda Mawson, Neil D. Merrett, Ivon Harliwong, Andrew Stone, Jaswinder S. Samra, Scott Wood, James R. Eshleman, Jeremy L. Humphris, Vincenzo Corbo, Anirban Maitra, Colin J. McKay, Andrew Barbour, Christopher W. Toon, Aldo Scarpa, Oliver Holmes, Angelika N. Christ, John V. Pearson, Giampaolo Tortora, Nick Waddell, Marc D. Jones, Jane Hair, Senel Idrisoglu, Richard A. Morgan
المساهمون: Cell Differentiation, Basic (bio-) Medical Sciences, Laboratory for Medical and Molecular Oncology
مصطلحات موضوعية: 0301 basic medicine, Male, DNA Mutational Analysis, Carcinoma, Pancreatic Ductal/genetics, DNA Mismatch Repair/genetics, medicine.disease_cause, DNA Mismatch Repair, 0302 clinical medicine, Sequencing, Pancreatic Adenocarcinoma, Aged, 80 and over, Mutation, Genome, Gastroenterology, Middle Aged, 3. Good health, MutS Homolog 2 Protein, 030220 oncology & carcinogenesis, Somatic Rearrangement, Cancer Genetics, DNA mismatch repair, Female, MutL Protein Homolog 1, MutS Homolog 2 Protein/genetics, Carcinoma, Pancreatic Ductal, Adult, DNA repair, Somatic hypermutation, Biology, MLH1, Proto-Oncogene Proteins p21(ras)/genetics, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Pancreatic cancer, medicine, Humans, Aged, Settore MED/06 - ONCOLOGIA MEDICA, Hepatology, MutL Protein Homolog 1/genetics, Cancer, medicine.disease, Pancreatic Neoplasms/genetics, Pancreatic Neoplasms, 030104 developmental biology, MSH2, Cancer research, Transcriptome
وصف الملف: application/pdf
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المؤلفون: Irene Dalai, Conrad Leonard, Eliana Amato, Andrew B. Barbour, Marc D. Jones, Rita T. Lawlor, Andreia V. Pinho, Amanda Mawson, Neil D. Merrett, Caterina Vicentini, Matteo Fassan, Ivon Harliwong, J. Lynn Fink, Giovanni Butturini, Anthony J. Gill, David Miller, Senel Idrisoglu, James G. Kench, Andrew V. Biankin, Ilse Rooman, Angela Chou, Marie-Claude Gingras, Katia Nones, Venessa T. Chin, Marco Miotto, Davide Antonello, Borislav Rusev, Paola Capelli, Rebecca A. Dagg, Christopher W. Toon, Jeremy L. Humphris, Samantha Bersani, David K. Chang, Nigel B. Jamieson, George Van Buren, Vincenzo Corbo, Jaswinder S. Samra, Stephen H. Kazakoff, Scott Wood, Claudio Bassi, Emily K. Colvin, Stefano Barbi, Amber L. Johns, Christopher J. Scarlett, Nicola Waddell, Jianmin Wu, Michael Lee, Michele Simbolo, Luca Landoni, Katarzyna O. Sikora, Michael C.J. Quinn, John V. Pearson, Nam Q. Nguyen, Angelo Paolo Dei Tos, Mark J. Cowley, Adnan Nagrial, Peter Bailey, Roger R. Reddel, Sean M. Grimmond, Peter Wilson, Skye McKay, Richard A. Gibbs, Jessica A. Lovell, Nikolajs Zeps, Kum Kum Khanna, Stefano Partelli, Timothy J. C. Bruxner, Janelle L. Harris, Andrea Mafficini, Barbara A. Leggett, Angelika N. Christ, Oliver Holmes, Craig Nourse, Krishna Epari, Felicity Newell, Ivana Cataldo, Paolo Pederzoli, Vicki L. J. Whitehall, Matthew J. Anderson, William E. Fisher, Maria Scardoni, Loretta Lau, Massimo Falconi, Ann-Marie Patch, Aldo Scarpa, Lorraine A. Chantrill, Shivashankar H. Nagaraj, Giampaolo Tortora, Sara Cingarlini, Elizabeth A. Musgrove, Ehsan Nourbakhsh, Maria Vittoria Davì, David A. Wheeler, Suzanne McLean, Fraser Duthie, Qinying Xu, Mark Pinese, Anna Malpaga, Nick Waddell, Emily S. Humphrey, Jonathan M. Harris, Marina Pajic, Hilda A. Pickett
المصدر: Nature. 550:548-548
مصطلحات موضوعية: 0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, Multidisciplinary, Breakpoint, RNA splicing, Computational biology, Biology, Genome
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المؤلفون: Jodi M, Saunus, Michael C J, Quinn, Ann-Marie, Patch, John V, Pearson, Peter J, Bailey, Katia, Nones, Amy E, McCart Reed, David, Miller, Peter J, Wilson, Fares, Al-Ejeh, Mythily, Mariasegaram, Queenie, Lau, Teresa, Withers, Rosalind L, Jeffree, Lynne E, Reid, Leonard, Da Silva, Admire, Matsika, Colleen M, Niland, Margaret C, Cummings, Timothy J C, Bruxner, Angelika N, Christ, Ivon, Harliwong, Senel, Idrisoglu, Suzanne, Manning, Craig, Nourse, Ehsan, Nourbakhsh, Shivangi, Wani, Matthew J, Anderson, J Lynn, Fink, Oliver, Holmes, Stephen, Kazakoff, Conrad, Leonard, Felicity, Newell, Darrin, Taylor, Nick, Waddell, Scott, Wood, Qinying, Xu, Karin S, Kassahn, Vairavan, Narayanan, Nur Aishah, Taib, Soo-Hwang, Teo, Yock Ping, Chow, kConFab, Parmjit S, Jat, Sebastian, Brandner, Adrienne M, Flanagan, Kum Kum, Khanna, Georgia, Chenevix-Trench, Sean M, Grimmond, Peter T, Simpson, Nicola, Waddell, Sunil R, Lakhani
المصدر: The Journal of pathology. 237(3)
مصطلحات موضوعية: Receptor, ErbB-4, Receptor, ErbB-3, Brain Neoplasms, Receptor, ErbB-2, Gene Expression Profiling, DNA Mutational Analysis, Gene Amplification, Gene Dosage, Genomics, Ligands, Immunohistochemistry, Enzyme Activation, Gene Expression Regulation, Neoplastic, Phenotype, Predictive Value of Tests, Mutation, Biomarkers, Tumor, Tumor Microenvironment, Humans, Genetic Predisposition to Disease, Molecular Targeted Therapy, Phosphorylation, Precision Medicine, Protein Kinase Inhibitors, Genetic Association Studies
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