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1دورية أكاديمية
المؤلفون: Adam J. Davenport, Ioana Neagoe, Nico Bräuer, Markus Koch, Andrea Rotgeri, Jens Nagel, Alexis Laux-Biehlmann, Frederic Machet, Anne-Marie Coelho, Susan Boyce, Nikisha Carty, Mark J. Gemkow, Stephen D. Hess, Thomas M. Zollner, Oliver M. Fischer
المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-2322
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2
المؤلفون: Douglas L, Orsi, Elisabeth, Pook, Nico, Bräuer, Anders, Friberg, Philip, Lienau, Christopher T, Lemke, Timo, Stellfeld, Ulf, Brüggemeier, Vera, Pütter, Hanna, Meyer, Maria, Baco, Stephanie, Tang, Andrew D, Cherniack, Lindsay, Westlake, Samantha A, Bender, Mustafa, Kocak, Craig A, Strathdee, Matthew, Meyerson, Knut, Eis, Jonathan T, Goldstein
المصدر: Journal of medicinal chemistry. 65(21)
مصطلحات موضوعية: PPAR gamma, Ligands
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3Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069
المؤلفون: Douglas L. Orsi, Elisabeth Pook, Nico Bräuer, Anders Friberg, Philip Lienau, Christopher T. Lemke, Timo Stellfeld, Ulf Brüggemeier, Vera Pütter, Hanna Meyer, Maria Baco, Stephanie Tang, Andrew D. Cherniack, Lindsay Westlake, Samantha A. Bender, Mustafa Kocak, Craig A. Strathdee, Matthew Meyerson, Knut Eis, Jonathan T. Goldstein
المصدر: Journal of Medicinal Chemistry. 65:14843-14863
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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المؤلفون: Douglas L. Orsi, Elisabeth Pook, Nico Bräuer, Anders Friberg, Philip Lienau, Christopher T. Lemke, Timo Stellfeld, Ulf Brüggemeier, Vera Pütter, Hanna Meyer, Maria Baco, Stephanie Tang, Andrew D. Cherniack, Lindsay Westlake, Samantha A. Bender, Mustafa Kocak, Craig A. Strathdee, Matthew Meyerson, Knut Eis, Jonathan T. Goldstein
المصدر: Journal of Medicinal Chemistry. 66:1082-1082
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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المؤلفون: Roman C. Hillig, Ioana Neagoe, Andreas Steinmeyer, Thomas M. Zollner, Stefanie Mesch, Henrik Dahllöf, Julie Klint, Simone Schulz, Vera Puetter, Reinhard Nubbemeyer, Antonius Ter Laak, Stefan Werner, Alexis Laux-Biehlmann, Nico Bräuer, Michaela Bairlein
المصدر: Journal of Medicinal Chemistry. 62:11194-11217
مصطلحات موضوعية: 0303 health sciences, Pregnane X receptor, CYP3A4, biology, Drug discovery, Chemistry, Cell growth, Antagonist, Pharmacology, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, In vivo, Drug Discovery, biology.protein, Molecular Medicine, Enzyme inducer, Receptor, 030304 developmental biology
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المؤلفون: Thomas M. Zollner, Antonius Ter Laak, Daryl S. Walter, Jens Nagel, Anne-Marie Coelho, Horst Irlbacher, Michaele Peters, Andrea Rotgeri, Marcus Koppitz, Andreas Steinmeyer, Nico Bräuer
المصدر: Bioorganic & Medicinal Chemistry Letters. 29:2700-2705
مصطلحات موضوعية: medicine.medical_treatment, Clinical Biochemistry, Carboxylic Acids, Endometriosis, Pain, Pharmaceutical Science, Prostaglandin, Inflammation, Pharmacology, 01 natural sciences, Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Downregulation and upregulation, In vivo, Drug Discovery, medicine, Animals, Humans, Enzyme Inhibitors, Prostaglandin E2, Molecular Biology, Prostaglandin-E Synthases, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Organic Chemistry, In vitro, Rats, 0104 chemical sciences, Molecular Docking Simulation, Disease Models, Animal, 010404 medicinal & biomolecular chemistry, Enzyme, chemistry, Molecular Medicine, Female, medicine.symptom, Prostaglandin E, medicine.drug
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7
المؤلفون: Mark J. Gemkow, Jens Nagel, Nikisha Carty, Alexis Laux-Biehlmann, Ioana Neagoe, Thomas M. Zollner, Frederic Machet, Markus Koch, Adam James Davenport, Nico Bräuer, Andrea Rotgeri, Stephen D. Hess, Anne-Marie Coelho, Oliver Fischer, Susan Boyce
المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)مصطلحات موضوعية: Purinergic P2X Receptor Antagonists, Reproductive disorders, Science, Endometriosis, Gene Expression, Bioinformatics, Ion channels in the nervous system, Article, Target validation, Cell Line, Membrane Potentials, Mice, Adenosine Triphosphate, Nerve Fibers, medicine, Animals, Humans, Receptor, Sensitization, Pharmacology, Neurogenic inflammation, Multidisciplinary, business.industry, Drug discovery, Pelvic pain, Antagonist, medicine.disease, Rats, body regions, Disease Models, Animal, medicine.anatomical_structure, Overactive bladder, Hyperalgesia, Neuroinflammatory Diseases, Somatosensory Disorders, Medicine, Female, medicine.symptom, business, Receptors, Purinergic P2X3
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المؤلفون: Stefan, Werner, Stefanie, Mesch, Roman C, Hillig, Antonius, Ter Laak, Julie, Klint, Ioana, Neagoe, Alexis, Laux-Biehlmann, Henrik, Dahllöf, Nico, Bräuer, Vera, Puetter, Reinhard, Nubbemeyer, Simone, Schulz, Michaela, Bairlein, Thomas M, Zollner, Andreas, Steinmeyer
المصدر: Journal of medicinal chemistry. 62(24)
مصطلحات موضوعية: Inflammation, Male, Purinergic P2X Receptor Antagonists, Cytochrome P-450 CYP3A Inducers, Pain, Apoptosis, Ligands, Rats, Mice, Inbred C57BL, Mice, Gene Expression Regulation, Enzyme Induction, Acetamides, Drug Discovery, Animals, Cytochrome P-450 CYP3A, Humans, Female, Rats, Wistar, Receptors, Purinergic P2X4, Cells, Cultured, Cell Proliferation
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المؤلفون: Stefan Bäurle, Olaf Peters, Gernot Langer, Ludwig Zorn, Antonius Ter Laak, Nico Bräuer, Ulrich Bothe, Daryl S. Walter, Jens Nagel, Thomas M. Zollner, Thorsten Blume, Cornelia Preusse, Antje Rottmann, Andreas Steinmeyer, Dieter Heldmann
المصدر: Journal of medicinal chemistry. 62(5)
مصطلحات موضوعية: medicine.medical_treatment, Prostaglandin E2 receptor, Endometriosis, Glucuronidation, Pharmacology, 01 natural sciences, 03 medical and health sciences, Structure-Activity Relationship, Drug Discovery, medicine, Structure–activity relationship, Humans, Prostaglandin E2, Receptor, 030304 developmental biology, 0303 health sciences, Chemistry, Antagonist, medicine.disease, 0104 chemical sciences, High-Throughput Screening Assays, 010404 medicinal & biomolecular chemistry, Molecular Medicine, lipids (amino acids, peptides, and proteins), Benzimidazoles, Female, Receptors, Prostaglandin E, EP4 Subtype, Prostaglandin E, medicine.drug
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المؤلفون: Ernst Schaumann, Nico Bräuer, Sylvia Dreeßen
المصدر: Tetrahedron Letters. 40:2921-2924
مصطلحات موضوعية: Silicon, chemistry, Cascade reaction, Organic Chemistry, Drug Discovery, chemistry.chemical_element, Biochemistry, Combinatorial chemistry, Domino