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1دورية أكاديمية
المؤلفون: Jonathan Wilson, Lei Cui, Costa Salojin, Anna Gardberg, Valerie Vivat, Jeffrey Lauer, Nico Cantone, Jacob Stuckey, Florence Poy, Ingrid Almeciga, Richard Cummings, Julian Levell, Jennifer Rocnik, Patrick Trojer
المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2051-1426
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المؤلفون: Alexander M. Taylor, Chris Bailey, Lisa D. Belmont, Robert Campbell, Nico Cantone, Alexandre Côté, Terry D. Crawford, Richard Cummings, Kevin DeMent, Martin Duplessis, Megan Flynn, Andrew C. Good, Hon-Ren Huang, Shivangi Joshi, Yves Leblanc, Jeremy Murray, Christopher G. Nasveschuk, Adrianne Neiss, Florence Poy, F. Anthony Romero, Peter Sandy, Yong Tang, Vickie Tsui, Laura Zawadzke, Robert J. Sims, James E. Audia, Steven F. Bellon, Steven R. Magnuson, Brian K. Albrecht, Andrea G. Cochran
المصدر: Journal of medicinal chemistry. 65(16)
مصطلحات موضوعية: DNA-Binding Proteins, Protein Domains, Drug Discovery, DNA Helicases, Molecular Medicine, Humans, Nuclear Proteins, Transcription Factors
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المؤلفون: Nico, Cantone, Richard T, Cummings, Patrick, Trojer
المصدر: Methods in molecular biology (Clifton, N.J.). 2529
مصطلحات موضوعية: Histone Methyltransferases, Methyltransferases, Enzyme Inhibitors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e6307eb2e796ea7fb058f60519f5bbdc
https://pubmed.ncbi.nlm.nih.gov/35733027 -
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المؤلفون: Nico Cantone, Richard T. Cummings, Patrick Trojer
المصدر: Histone Methyltransferases ISBN: 9781071624807
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::94aa147fd5e76b5acf64df6cd47d396b
https://doi.org/10.1007/978-1-0716-2481-4_20 -
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المؤلفون: Anna S. Gardberg, Francois Brucelle, Robert J. Sims, Nico Cantone, Richard T. Cummings, Florence Poy, Archana Bommi-Reddy, Julian Levell, Jonathan E. Wilson, Chirag Patel, Annissa J. Huhn, Gaurav Patel
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Indole test, Histone Acetyltransferases, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Neurodegeneration, Histone acetyltransferase, Pharmacology, medicine.disease, 01 natural sciences, Biochemistry, 0104 chemical sciences, Bioavailability, 010404 medicinal & biomolecular chemistry, Drug Discovery, biology.protein, medicine, Potency, CREB-binding protein, EP300
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المؤلفون: Ingrid Almeciga, Costa Salojin, Julian Levell, Anna Gardberg, Patrick Trojer, Lei Cui, Richard D. Cummings, Jennifer Rocnik, Valerie Vivat, Jacob I. Stuckey, Nico Cantone, Florence Poy, Jonathan E. Wilson, Jeffrey Lauer
المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
مصطلحات موضوعية: Pharmacology, Cancer Research, Innate immune system, Chemistry, Immunology, Cell, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Transfection, Acquired immune system, Immune checkpoint, Immune system, medicine.anatomical_structure, Oncology, Cell culture, Immunity, Cancer research, medicine, Molecular Medicine, Immunology and Allergy, RC254-282
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المؤلفون: Srividya Balasubramanian, Robert K. Campbell, Patrick Trojer, Christina O. Lee, Jon R. Wilson, Emmanuel Normant, Les A. Dakin, Martin Duplessis, Brian K. Albrecht, Jean-Christophe Harmange, Rishi G. Vaswani, James E. Audia, Priyadarshini Iyer, Andrew Simon Cook, Neil Justin, Steven J. Gamblin, Nico Cantone, Andrew C. Good, Feng Zhao, Richard T. Cummings, Steven F. Bellon, Christopher G. Nasveschuk, Shuyang Chen, Ying Zhang, Victor S. Gehling
المصدر: Journal of Medicinal Chemistry. 59:9928-9941
مصطلحات موضوعية: 0301 basic medicine, Indole test, biology, medicine.drug_class, Chemistry, EZH2, Carboxamide, macromolecular substances, Methylation, 3. Good health, 03 medical and health sciences, 030104 developmental biology, Histone, Biochemistry, Histone methyltransferase, Drug Discovery, medicine, biology.protein, Molecular Medicine, Structure–activity relationship, PRC2
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المؤلفون: Valérie Vivat, Patrick Trojer, Jehrod Burnett Brenneman, James E. Audia, Jennifer A. Mertz, Victor S. Gehling, Shilpi Arora, Ashwin Ramakrishnan, Richard T. Cummings, Ludivine Moine, Jacob I. Stuckey, Robert J. Sims, Nico Cantone, Alexandre Côté, Avinash Khanna, Julian Levell
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, DMSO, dimethylsulfoxide, SPR, surface plasmon resonance, Mice, SCID, macromolecular substances, Computational biology, small-molecule kinetics, Biochemistry, TR-FRET-binding kinetics, Small Molecule Libraries, 03 medical and health sciences, Allosteric Regulation, femtomolar, TR-FRET, time-resolved fluorescence energy transfer, SAR, structure–activity relationship, Drug Discovery, Animals, Humans, Structure–activity relationship, Enhancer of Zeste Homolog 2 Protein, Single agent, Biological evidence, EZH2, Enzyme Inhibitors, Molecular Biology, residence time, Binding affinities, 030102 biochemistry & molecular biology, biology, Chemistry, SA-APC, streptavidin allophycocyanin, Biological activity, Cell Biology, SKR, structure–kinetic relationship, 030104 developmental biology, Histone methyltransferase, biology.protein, Female, PRC2, Research Article, PRC2, polycomb repressive complex 2, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d7df285623b842ff86e83d86e40d53
https://doi.org/10.1016/j.jbc.2021.100349 -
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المؤلفون: Robert M. Campbell, Yves Leblanc, James E. Audia, Jennifer A. Mertz, Brian K. Albrecht, Michael R. Cooper, Jeffrey G. Supko, Emmanuel Normant, Florence Poy, Christopher G. Nasveschuk, Richard T. Cummings, Michael C. Hewitt, Adrianne Neiss, Victor S. Gehling, Louise Bergeron, Jean-Christophe Harmange, Peter Sandy, Michael O'Meara, Alexander M. Taylor, Robert J. Sims, Nico Cantone, Eneida Pardo, Alexandre Côté, Shivangi Joshi, Hariharan Jayaram, Rishi G. Vaswani, Steve Bellon
المصدر: Journal of Medicinal Chemistry. 59:1330-1339
مصطلحات موضوعية: 0301 basic medicine, Genes, myc, Antineoplastic Agents, Cell Cycle Proteins, Biology, Proto-Oncogene Proteins c-myc, Mice, 03 medical and health sciences, Dogs, 0302 clinical medicine, In vivo, Cell Line, Tumor, Drug Discovery, Gene expression, Animals, Humans, Nuclear protein, Transcription factor, Gene, Clinical Trials as Topic, Nuclear Proteins, hemic and immune systems, Azepines, Xenograft Model Antitumor Assays, Molecular biology, Rats, Bromodomain, Chromatin, Gene Expression Regulation, Neoplastic, Leukemia, Myeloid, Acute, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, Molecular Medicine, Transcription Factors
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المؤلفون: Barbara M. Bryant, Patrick Trojer, Emmanuel Normant, Richard T. Cummings, Nico Cantone, Victor S. Gehling, William D. Bradley, Les A. Dakin, Rishi G. Vaswani, Chih-Chi Yuan, Kaylyn E. Williamson, Robert E. Campbell, Jean-Christophe Harmange, James E. Audia, Jacqui Méndez, Jennifer Busby, Christopher G. Nasveschuk, Feng Zhao, Danette L. Daniels, Brian K. Albrecht, Shivani Garapaty-Rao, Andrew S. Cook, Charlie Hatton, Srividya Balasubramanian, Shilpi Arora, Priyadarshini Iyer
المصدر: Chemistry & Biology. 21(11):1463-1475
مصطلحات موضوعية: Transplantation, Heterologous, Clinical Biochemistry, Follicular lymphoma, Mice, Nude, Apoptosis, macromolecular substances, Biology, Methylation, Biochemistry, Article, Histones, Small Molecule Libraries, Histone H3, Mice, immune system diseases, Cell Line, Tumor, hemic and lymphatic diseases, Drug Discovery, medicine, Animals, Humans, Amino Acid Sequence, Enzyme Inhibitors, Molecular Biology, Cell Proliferation, Pharmacology, Lymphoma, Non-Hodgkin, EZH2, fungi, Polycomb Repressive Complex 2, Germinal center, General Medicine, medicine.disease, BCL10, Lymphoma, Non-Hodgkin's lymphoma, Disease Models, Animal, Kinetics, Mutation, Cancer research, Molecular Medicine, lipids (amino acids, peptides, and proteins), Lymphoma, Large B-Cell, Diffuse, Peptides, Diffuse large B-cell lymphoma