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1دورية أكاديمية
المؤلفون: Amélie Laversin, Robin Dufossez, Raphaël Bolteau, Romain Duroux, Séverine Ravez, Sergio Hernandez-Tapia, Martin Fossart, Mathilde Coevoet, Maxime Liberelle, Saïd Yous, Nicolas Lebègue, Patricia Melnyk
المصدر: Molecules, Vol 29, Iss 16, p 3847 (2024)
مصطلحات موضوعية: A2A receptor antagonist, quinazoline, fluorescence polarization, cAMP assay, Organic chemistry, QD241-441
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Aurélie Hurtevent, Morgan Le Naour, Veronique Leclerc, Pascal Carato, Patricia Melnyk, Nathalie Hennuyer, Bart Staels, Monique Beucher-Gaudin, Daniel-Henri Caignard, Catherine Dacquet, Nicolas Lebegue
المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 524-538 (2020)
مصطلحات موضوعية: type 2 diabetes, ppar, spparγm, benzothiazol-2-one, body weight gain, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: Camille Quenon, Thierry Hennebelle, Jean-François Butaud, Raimana Ho, Jennifer Samaillie, Christel Neut, Tamatoa Lehartel, Céline Rivière, Ali Siah, Natacha Bonneau, Sevser Sahpaz, Sébastien Anthérieu, Nicolas Lebegue, Phila Raharivelomanana, Vincent Roumy
المصدر: Life, Vol 12, Iss 5, p 733 (2022)
مصطلحات موضوعية: Society Islands, traditional medicine, phytochemical, antimicrobial, salicylic compounds, Syzygium malaccense, Science
وصف الملف: electronic resource
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4دورية أكاديمية
المؤلفون: Joel T. Mague, Shaaban K. Mohamed, Mehmet Akkurt, Hussein El-Kashef, Nicolas Lebegue, Mustafa R. Albayati
المصدر: IUCrData, Vol 1, Iss 12, p x161959 (2016)
مصطلحات موضوعية: crystal structure, hydrogen bonds, C—H...π(ring) interactions, thiazolidinones, azomethene, Crystallography, QD901-999
وصف الملف: electronic resource
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المؤلفون: Nathalie Hennuyer, Nicolas Lebegue, Morgan Le Naour, Monique Beucher-Gaudin, Daniel-Henri Caignard, Pascal Carato, Catherine Dacquet, Bart Staels, Veronique Leclerc, Patricia Melnyk, Aurelie Hurtevent
المساهمون: Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837 [JPArc], CIC - Poitiers, Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 [RNMCD], Institut de Recherches Internationales Servier [Suresnes] [IRIS], Institut de Recherches SERVIER [IRS], Université de Lille, Inserm, CHU Lille, Université de Lille, LillOA, Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837 (JPArc), Université Lille Nord de France (COMUE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Université de Poitiers-Centre hospitalier universitaire de Poitiers (CHU Poitiers)-Direction Générale de l'Organisation des Soins (DGOS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires (RNMCD - U1011), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 (RNMCD), Institut de Recherches SERVIER (IRS), Lille Neurosciences & Cognition - U 1172 (LilNCog (ex-JPARC)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de Recherches Internationales Servier [Suresnes] (IRIS), Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U1172 Inserm - U837 (JPArc), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Lille Nord de France (COMUE)-Université de Lille, Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U1011 (RNMCD)
المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020, 35 (1), pp.524-538. ⟨10.1080/14756366.2020.1713771⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2020, Journal of Enzyme Inhibition and Medicinal Chemistry, 35 (1), pp.524-538. ⟨10.1080/14756366.2020.1713771⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2020, 35 (1), pp.524-538. ⟨10.1080/14756366.2020.1713771⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 524-538 (2020)مصطلحات موضوعية: Male, Agonist, Scaffold, body weight gain, medicine.drug_class, Stereochemistry, [SDV]Life Sciences [q-bio], [CHIM.THER] Chemical Sciences/Medicinal Chemistry, Mice, Obese, Peroxisome proliferator-activated receptor, RM1-950, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Ligands, PPAR, 01 natural sciences, Article, PPAR agonist, Mice, Structure-Activity Relationship, SPPARγM, Chlorocebus aethiops, Drug Discovery, medicine, Animals, Hypoglycemic Agents, PPAR alpha, Benzothiazoles, [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Pharmacology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, Phenylpropionates, 010405 organic chemistry, Chemistry, Type 2 diabetes, General Medicine, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, 3. Good health, 0104 chemical sciences, Molecular Docking Simulation, PPAR gamma, 010404 medicinal & biomolecular chemistry, Diabetes Mellitus, Type 2, COS Cells, benzothiazol-2-one, Therapeutics. Pharmacology, SPPARM
وصف الملف: application/octet-stream; application/pdf
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المؤلفون: Maxime Liberelle, Philippe Delagrange, Amélie Laversin, Daniel Henri Caignard, Nicolas Lebegue, Mohamed Ettaoussi, Saïd Yous, Marouane Rami, Patricia Melnyk, Brandon Vreulz
المصدر: ChemMedChem. 17(3)
مصطلحات موضوعية: Agonist, Stereochemistry, medicine.drug_class, Receptors, Melatonin, Ligands, Biochemistry, Melatonin receptor, Partial agonist, chemistry.chemical_compound, Structure-Activity Relationship, Cricetulus, Drug Discovery, medicine, Agomelatine, Animals, Humans, General Pharmacology, Toxicology and Pharmaceutics, Isoquinoline, Cells, Cultured, Naphthalene, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Tetrahydroisoquinoline, Organic Chemistry, Isoquinolines, Melatonergic, Molecular Docking Simulation, Molecular Medicine, medicine.drug
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المؤلفون: Romain Vasseur, Romain Magnez, N Jonckheere, Nicolas Renault, Nicolas Stoup, Nicolas Lebegue, Isabelle Van Seuningen, Patricia Melnyk, Xavier Thuru, Maxime Liberelle, Céline Schulz
المصدر: The FASEB Journal. 35
مصطلحات موضوعية: Chemistry, Cancer cell, Genetics, Cancer research, Molecular Biology, Biochemistry, Biotechnology
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المؤلفون: Nicolas Lebegue, Nicolas Jonckheere, Patricia Melnyk, Isabelle Van Seuningen, Maxime Liberelle
المساهمون: Lille Neurosciences & Cognition - U 1172 (LilNCog (ex-JPARC)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Cancer Heterogeneity, Plasticity and Resistance to Therapies - UMR 9020 - U 1277 (CANTHER), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Lille Neurosciences & Cognition - U 1172 (LilNCog)
المصدر: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2020, 63 (10), pp.5074-5088. ⟨10.1021/acs.jmedchem.9b02001⟩
Journal of Medicinal Chemistry, 2020, 63 (10), pp.5074-5088. ⟨10.1021/acs.jmedchem.9b02001⟩مصطلحات موضوعية: Cell signaling, Receptor, ErbB-2, Druggability, Antineoplastic Agents, [SDV.CAN]Life Sciences [q-bio]/Cancer, Computational biology, 01 natural sciences, Protein Structure, Secondary, Receptor tyrosine kinase, 03 medical and health sciences, Drug Delivery Systems, Protein structure, Drug Discovery, medicine, Animals, Humans, Amino Acid Sequence, Receptor, Peptide sequence, 030304 developmental biology, 0303 health sciences, Epidermal Growth Factor, biology, Chemistry, Cell Membrane, Mucin, Mucins, Epithelium, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, medicine.anatomical_structure, biology.protein, Molecular Medicine, Signal Transduction
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المؤلفون: Isabelle Van Seuningen, Nicolas Lebegue, Romain Magnez, Xavier Thuru, Nicolas Stoup, Patricia Melnyk, Céline Schulz, Maxime Liberelle, Romain Vasseur, Nicolas Renault, Nicolas Jonckheere
المصدر: Cancer Research. 81:LB106-LB106
مصطلحات موضوعية: Cancer Research, Chemistry, Cell growth, Cancer, medicine.disease, Oncology, Tumor progression, Pancreatic cancer, Cancer cell, medicine, Cancer research, Protein kinase B, PI3K/AKT/mTOR pathway, Proto-oncogene tyrosine-protein kinase Src
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2619faad55df45b123a05345003031ed
https://doi.org/10.1158/1538-7445.am2021-lb106 -
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المؤلفون: Patricia Melnyk, Isabelle Van Seuningen, Nicolas Lebegue, Maxime Liberelle, Anne-Sophie Drucbert, Catherine Foulon, Romain Magnez, Séverine Ravez, Yamina Bencheikh, Camille Quenon, Xavier Thuru
المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
مصطلحات موضوعية: Multidisciplinary, Microscale thermophoresis, Chemistry, lcsh:R, lcsh:Medicine, Nanotechnology, lcsh:Q, lcsh:Science