المؤلفون: Caroline Eykens, Elisabeth Rossaert, Sandra Duqué, Laura Rué, André Bento-Abreu, Nicole Hersmus, Annette Lenaerts, Axelle Kerstens, Nikky Corthout, Sebastian Munck, Philip Van Damme, Matthew G. Holt, Georg von Jonquires, Matthias Klugmann, Ludo Van Den Bosch, Wim Robberecht

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 508-519 (2021)

مصطلحات موضوعية: amyotrophic lateral sclerosis, oligodendrocytes, monocarboxylate transporter 1, adeno-associated virus, gene therapy, Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050121000061; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/5b90cd6bd1ee48538c98aa1f5b5b50c6

المؤلفون: Elke Bogaert, Steven Boeynaems, Masato Kato, Lin Guo, Thomas R. Caulfield, Jolien Steyaert, Wendy Scheveneels, Nathalie Wilmans, Wanda Haeck, Nicole Hersmus, Joost Schymkowitz, Frederic Rousseau, James Shorter, Patrick Callaerts, Wim Robberecht, Philip Van Damme, Ludo Van Den Bosch

المصدر: Cell Reports, Vol 24, Iss 3, Pp 529-537.e4 (2018)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124718309975; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/4c45c2f32f6344e9bdc9bf9b4b22882d

المؤلفون: Wenting Guo, Haibo Wang, Arun Kumar Tharkeshwar, Julien Couthouis, Elke Braems, Pegah Masrori, Evelien Van Schoor, Yannan Fan, Karan Ahuja, Matthieu Moisse, Maarten Jacquemyn, Rodrigo Furtado Madeiro da Costa, Madhavsai Gajjar, Sriram Balusu, Tine Tricot, Laura Fumagalli, Nicole Hersmus, Rekin's Janky, Francis Impens, Pieter Vanden Berghe, Ritchie Ho, Dietmar Rudolf Thal, Rik Vandenberghe, Muralidhar L. Hegde, Siddharthan Chandran, Bart De Strooper, Dirk Daelemans, Philip Van Damme, Ludo Van Den Bosch, Catherine Verfaillie

المصدر: Guo, W, Wang, H, Kumar Tharkeshwar, A, Couthouis, J, Braems, E, Masrori, P, Van Schoor, E, Fan, Y, Ahuja, K, Moisse, M, Jacquemyn, M, Furtado Madeiro Da Costa, R, Gajjar, M, Balusu, S, Tricot, T, Fumagalli, L, Hersmus, N, Janky, R, Impens, F, Vanden Berghe, P, Ho, R, Thal, D R, Vandenberghe, R, Hegde, M L, Chandran, S, De Strooper, B, Daelemans, D, Van Damme, P, Van Den Bosch, L & Verfaillie, C 2022, ' CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity ', Alzheimer's & Dementia . https://doi.org/10.1002/alz.12760
ALZHEIMERS & DEMENTIA

مصطلحات موضوعية: p53, amyotrophic lateral sclerosis, Epidemiology, Cas9 screen, frontotemporal dementia, P53 TRANSACTIVATION DOMAIN, Cellular and Molecular Neuroscience, CRISPR/Cas9 screen, Developmental Neuroscience, C9orf72, PR toxicity, BINDING, Medicine and Health Sciences, human pluripotent stem cells, Health Policy, KINASES, NEURODEGENERATION, Biology and Life Sciences, Psychiatry and Mental health, CRISPR, CELLS, DNA damage, Neurology (clinical), Geriatrics and Gerontology, REGULATOR, NEK6

وصف الملف: application/pdf; Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5deef81adf4bd7c539926b067aaf727
https://doi.org/10.1002/alz.12760

المؤلفون: Pegah Masrori, Baukje Bijnens, Kristofer Davie, Suresh Kumar Poovathingal, Annet Storm, Nicole Hersmus, Laura Fumagalli, Ludo Van Den Bosch, Mark Fiers, Dietmar Thal, Renzo Mancuzo, Philip Van Damme

المصدر: Sunday, April 23.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7afee838032a84341897783371083e4d
https://doi.org/10.1212/wnl.0000000000203562

المؤلفون: Alberto Catanese, Sandeep Rajkumar, Daniel Sommer, Pegah Masrori, Nicole Hersmus, Philip Van Damme, Simon Witzel, Albert Ludolph, Ritchie Ho, Tobias M Boeckers, Medhanie Mulaw

المصدر: Brain Advance online publication, 1-13 (2023). doi:10.1093/brain/awad075

مصطلحات موضوعية: deep learning, motor neurons, Neurology (clinical), ddc:610, ALS, omics

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eeffc6de1cc5c84207d6b60a926ae5e

المؤلفون: Pegah Masrori, Baukje Bijnens, Kristofer Davie, Suresh Kumar Poovathingal, Annet Storm, Nicole Hersmus, Laura Fumagalli, Ludo Van Den Bosch, Mark Fiers, Dietmar Rudolf Thal, Renzo Mancuso, Philip Van Damme

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47a6baf180e3336075a981c453f852e
https://doi.org/10.21203/rs.3.rs-2163908/v1

المؤلفون: Elke Braems, Valérie Bercier, Evelien Van Schoor, Kara Heeren, Jimmy Beckers, Laura Fumagalli, Lieselot Dedeene, Matthieu Moisse, Ilse Geudens, Nicole Hersmus, Arpan R. Mehta, Bhuvaneish T. Selvaraj, Siddharthan Chandran, Ritchie Ho, Dietmar R. Thal, Philip Van Damme, Bart Swinnen, Ludo Van Den Bosch

المصدر: Braems, E, Bercier, V, Van Schoor, E, Heeren, K, Beckers, J, Fumagalli, L, Dedeene, L, Moisse, M, Geudens, I, Hersmus, N, Mehta, A R, Selvaraj, B T, Chandran, S, Ho, R, Thal, D R, Van Damme, P, Swinnen, B & Van Den Bosch, L 2022, ' HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS ', Acta Neuropathologica . https://doi.org/10.1007/s00401-022-02471-y

مصطلحات موضوعية: EXPRESSION, Clinical Neurology, AMYOTROPHIC-LATERAL-SCLEROSIS, Pathology and Forensic Medicine, Heterogeneous-Nuclear Ribonucleoprotein K, Cellular and Molecular Neuroscience, Pick Disease of the Brain, C9orf72, BINDING, Pathology, Animals, RNA, Antisense, PHOSPHORYLATION, Zebrafish, RIBONUCLEOTIDE REDUCTASE M2, P53, DNA Repeat Expansion, Science & Technology, HEXANUCLEOTIDE REPEAT, C9orf72 Protein, HNRNPK, Amyotrophic Lateral Sclerosis, Neurosciences, NEURODEGENERATION, RNA toxicity, REPEAT EXPANSION, Frontotemporal Dementia, RRM2, RNA, DNA damage, MOTOR-NEURONS, Neurology (clinical), Neurosciences & Neurology, ALS, Life Sciences & Biomedicine, DNA Damage

وصف الملف: Print-Electronic; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9240636f5d047c2ad0640a9104ed31da
https://lirias.kuleuven.be/handle/20.500.12942/702190

المؤلفون: Mafalda Rizzuti, Valentina Melzi, Delia Gagliardi, Davide Resnati, Megi Meneri, Laura Dioni, Pegah Masrori, Nicole Hersmus, Koen Poesen, Martina Locatelli, Fabio Biella, Rosamaria Silipigni, Valentina Bollati, Nereo Bresolin, Giacomo Pietro Comi, Philip Van Damme, Monica Nizzardo, Stefania Corti

المصدر: Cellular and Molecular Life Sciences. 79

مصطلحات موضوعية: EXPRESSION, Biochemistry & Molecular Biology, STRESS, TDP-43, Induced Pluripotent Stem Cells, BIOMARKERS, C9ORF72, CSF, Cell Communication, Exosomes, Cellular and Molecular Neuroscience, Humans, Molecular Biology, Cells, Cultured, miRNA, Motor neurons, Motor Neurons, Pharmacology, Science & Technology, HEXANUCLEOTIDE REPEAT, MIRNA BIOGENESIS, MUTATIONS, Amyotrophic Lateral Sclerosis, Cell Biology, GENE, MicroRNAs, DIFFERENTIATION, Gene Expression Regulation, Case-Control Studies, Molecular Medicine, ALS, Life Sciences & Biomedicine

وصف الملف: Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084db4bbcc1c27ce9ee6db47bda2fc6a
https://doi.org/10.1007/s00018-022-04217-1

المؤلفون: Sebastian Munck, Ludo Van Den Bosch, Georg von Jonquires, Matthias Klugmann, Matthew Holt, Laura Rué, Axelle Kerstens, Philip Van Damme, André Bento-Abreu, Annette Lenaerts, Caroline Eykens, Elisabeth Rossaert, Nicole Hersmus, Sandra I Duque, Nikky Corthout, Wim Robberecht

المصدر: Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 508-519 (2021)

مصطلحات موضوعية: 0301 basic medicine, amyotrophic lateral sclerosis, lcsh:QH426-470, Transgene, oligodendrocytes, adeno-associated virus, Biology, Gene delivery, medicine.disease_cause, 03 medical and health sciences, 0302 clinical medicine, Genetics, medicine, lcsh:QH573-671, Amyotrophic lateral sclerosis, Molecular Biology, Adeno-associated virus, lcsh:Cytology, Survival of motor neuron, monocarboxylate transporter 1, Motor neuron, medicine.disease, gene therapy, Oligodendrocyte, lcsh:Genetics, 030104 developmental biology, Monocarboxylate transporter 1, medicine.anatomical_structure, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Original Article, Neuroscience

وصف الملف: Electronic-eCollection

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7389a5159086b6f59c20f4329f5fa18a
http://europepmc.org/articles/PMC7878966

المؤلفون: Robert Prior, Stijn Verschoren, Katlijn Vints, Tom Jaspers, Elisabeth Rossaert, Yvonne E. Klingl, Alessio Silva, Nicole Hersmus, Philip Van Damme, Ludo Van Den Bosch

المصدر: Molecular neurobiologyReferences. 59(6)

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, SCHWANN-CELLS, Neuroscience (miscellaneous), RGFP966, Histone Deacetylases, ACTIVATION, PATHWAY, Cellular and Molecular Neuroscience, Myelination, Mice, Phosphatidylinositol 3-Kinases, Charcot-Marie-Tooth Disease, HISTONE DEACETYLASE 3, HDAC3 inhibition, Animals, MACROPHAGES, MARIE-TOOTH-DISEASE, Inflammation, Science & Technology, COMPLEX, Neurosciences, MAPK, Schwann cell, DUPLICATION, Rats, Disease Models, Animal, Neurology, CMT1A, GROWTH, Neurosciences & Neurology, Schwann Cells, Life Sciences & Biomedicine, Demyelinating Diseases

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6502b89e7d05bb11871924ebaef4d78
https://pubmed.ncbi.nlm.nih.gov/35320455