المؤلفون: Sumitra Ramachandran, Angela A. Dunne, Neil Derek Miller, Laiq Chaudry, Vincent Jaquet, Craig Allan, Aleksandra Filippova, Jean Lim, Ceri H. Davies, Agnes B. Ong, May Thu Ma, Shabina Nasir, Woei Shin Chen, Nicole Y. Ye, Edward R. Browne, Kiew Ching K Lee, Shihua Liao, Douglas G. Johns, Angela Bridges, Yasuji Matsuoka, Chiu Cheong Aw, A. Richard Rutter, Adeline L.W. Chueng, Dizheng Li, Deborah W. Chen, Sri Mulyanidewi, Sarah Duncan, Tamara Seredenina, Gary Pettman, Kazufumi Hirano, Pamela P. Oon

المصدر: Antioxidants & redox signaling, Vol. 23, No 5 (2015) pp. 358-374

مصطلحات موضوعية: Male, Physiology, Clinical Biochemistry, Aminopyridines, ddc:616.07, medicine.disease_cause, Biochemistry, Rats, Sprague-Dawley, Enzyme Inhibitors / therapeutic use, Membrane Glycoproteins / metabolism, Drug Discovery, Enzyme Inhibitors, Pancreatitis / drug therapy, Cells, Cultured, General Environmental Science, chemistry.chemical_classification, Sulfonamides, Membrane Glycoproteins, NADPH oxidase, biology, Chemistry, Enzyme Inhibitors / pharmacology, respiratory system, Small molecule, 3. Good health, Aminopyridines / chemistry, NADPH Oxidase 2, cardiovascular system, Sulfonamides / chemistry, circulatory and respiratory physiology, inorganic chemicals, In vivo, Forum Original Research Communication, medicine, Animals, NADPH Oxidases / metabolism, Molecular Biology, NOx, Sulfonamides / pharmacology, Reactive oxygen species, Aminopyridines / pharmacology, NADPH Oxidases / antagonists & inhibitors, Reactive Oxygen Species / metabolism, NADPH Oxidases, Cell Biology, In vitro, Mice, Inbred C57BL, Enzyme, Pancreatitis, Membrane Glycoproteins / antagonists & inhibitors, biology.protein, General Earth and Planetary Sciences, Reactive Oxygen Species, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7ea3e136424a97ddab898f120e2665
https://europepmc.org/articles/PMC4545375/

المؤلفون: Chun Li, Véronique Dartois, Jeanette Wu, Suzanne Skolnik, Thierry T. Diagana, Thomas H. Keller, Advait Nagle, David Plouffe, Maria Tan, Matthias Rottmann, Xuena Lin, Arnab K. Chatterjee, Jonathan Chang, Elizabeth A. Winzeler, Suresh B. Lakshminarayana, Fenghua Liu, Kerstin Gagaring, John Isbell, Tao Wu, William Tan, Christopher Caldwell, Richard Glynne, Zhong Chen, Christoph Fischli, David C. Tully, Anne Goh, Tove Tuntland, Min Low Kang, Nicole Y. Ye, Jared Ek, Reto Brun, Hui Qing Ang, Rachel Borboa, Thomas Hollenbeck, Jianling Wang, Peiting Zeng, Kelli L. Kuhen, Caroline Francek

المصدر: Journal of medicinal chemistry. 54(14)

مصطلحات موضوعية: Plasmodium berghei, Plasmodium falciparum, Drug Resistance, Parasitemia, Pharmacology, Piperazines, Cell Line, chemistry.chemical_compound, Antimalarials, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, In vivo, Drug Discovery, parasitic diseases, medicine, Benzene Derivatives, Potency, Animals, Humans, Amino Acids, Mice, Inbred BALB C, Aniline Compounds, biology, Chemistry, Imidazoles, Hit to lead, medicine.disease, biology.organism_classification, Malaria, Rats, Drug development, Molecular Medicine, Female, Lead compound

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d868962b7620c4673d34cdecd094cd
https://pubmed.ncbi.nlm.nih.gov/21644570