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المؤلفون: Astrid L. Basse, Karen N. Nielsen, Iuliia Karavaeva, Lars R. Ingerslev, Tao Ma, Jesper F. Havelund, Thomas S. Nielsen, Mikkel Frost, Julia Peics, Emilie Dalbram, Morten Dall, Juleen R. Zierath, Romain Barrès, Nils J. Færgeman, Jonas T. Treebak, Zachary Gerhart-Hines
المصدر: Basse, A L, Nielsen, K N, Karavaeva, I, Ingerslev, L R, Ma, T, Havelund, J F, Nielsen, T S, Frost, M, Peics, J, Dalbram, E, Dall, M, Zierath, J R, Barrès, R, Færgeman, N J, Treebak, J T & Gerhart-Hines, Z 2023, ' NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner ', Proceedings of the National Academy of Sciences of the United States of America, vol. 120, no. 14, e2220102120 . https://doi.org/10.1073/pnas.2220102120
مصطلحات موضوعية: Multidisciplinary, Adipose Tissue, Brown/metabolism, Obesity/metabolism, Nicotinamide Phosphoribosyltransferase/genetics, Cytokines/metabolism, Animals, Circadian Rhythm/physiology, NAD/metabolism
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c273dfdf97b93fab97fdc623e5cb7f38
https://doi.org/10.1073/pnas.2220102120 -
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المؤلفون: Carmen Sonntag, Laura A. Galvis, Phong D. Nguyen, Fernando J. Rossello, Jeroen Bakkers, Christophe Marcelle, Kelly L. Rogers, Verena C. Wimmer, Ziad Julier, Abdulsalam I. Isiaku, Thomas Boudier, Mikaël M. Martino, Dhanushika Ratnayake, Silke Berger, Jean Tan, Graham J. Lieschke, A.J. Wood, Peter D. Currie, Viola Oorschot
المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research
المصدر: Nature, 591(7849), 281-287. Nature Publishing Group
مصطلحات موضوعية: 0301 basic medicine, Male, Nicotinamide phosphoribosyltransferase, Inbred C57BL, Myoblasts, chemistry.chemical_compound, Mice, 0302 clinical medicine, Single-cell analysis, Receptors, Myocyte, Macrophage, PAX7 Transcription Factor/metabolism, RNA-Seq, Stem Cell Niche, Nicotinamide Phosphoribosyltransferase, Zebrafish, Receptors, CCR5/genetics, Multidisciplinary, PAX7 Transcription Factor, Matrix Metalloproteinase 9/genetics, Cell biology, medicine.anatomical_structure, Matrix Metalloproteinase 9, Skeletal/cytology, 030220 oncology & carcinogenesis, Muscle, Zebrafish/immunology, Stem cell, Single-Cell Analysis, Regeneration/physiology, Receptors, CCR5, Nicotinamide Phosphoribosyltransferase/genetics, Biology, 03 medical and health sciences, medicine, Regeneration, Animals, Humans, Progenitor cell, Muscle, Skeletal, Cell Proliferation, Innate immune system, Animal, Macrophages, Skeletal muscle, Macrophages/cytology, CCR5/genetics, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, chemistry, Muscle, Skeletal/cytology, Disease Models, Myoblasts/cytology
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المؤلفون: Joffrey Zoll, Jean-François Decaux, Mathias Mericskay, Marie Breton, Anne Garnier, Boris Manoury, Mélanie Gressette, Cynthia Tannous, Jérôme Piquereau, Charles Brenner, Nicolas Diguet, István Baczkó, Samuel A.J. Trammell, Jocelyne Blanc, Zhenlin Li, Anne Gouge, Nathalie Mougenot, Gareth G. Lavery, Robin Deloux
المساهمون: Adaptation Biologique et Vieillissement = Biological Adaptation and Ageing (B2A), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Signalisation et physiopathologie cardiovasculaire (UMRS1180), Institut National de la Santé et de la Recherche Médicale (INSERM), Phénotypage du petit animal (UMS28), Université Pierre et Marie Curie - Paris 6 (UPMC), Détoxication et réparation tissulaire, Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de Photophysique et Photochimie Supramoléculaires et Macromoléculaires (PPSM), École normale supérieure - Cachan (ENS Cachan)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche Cardiovasculaire de Lariboisiere, Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), This study was supported by the Association Française contre les Myopathies (AFM N 16282), the Agence Nationale de la Recherche (ANR) grant NAD-Heart ANR-17-CE17-0015-01 and ANR-08-GENOPAT-038, Fondation de France grant 00075811 and fundings from Institut National pour la Santé Et la Recherche Médicale (INSERM), Center National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie Paris 6, and University Paris Sud. Drs Diguet and Tannous, and Mr Deloux were supported by a PhD fellowship of French Ministère de la Recherche et de l’Enseignement Supérieur. Dr Diguet was further supported by a 1-year PhD fellowship from AFM. Dr Brenner is supported by the Roy J. Carver Trust. GGL is supported by a Wellcome Trust Senior Fellowship (104612/Z/14/Z)., The authors thank V. Veksler and R. Ventura-Clapier (Inserm UMR-S 1180) for expert advice on respiration assays, Luc Bertrand (UCL, Belgium) for expert advice on AMPK detection, A. Angelini (UMR 8256) for technical help in these assays, A. Grosfeld (UMR 8256) for preliminary setup experiments for Nmrk2 cloning, Florence Lefebvre for adult rat cardiomyocyte isolation., ANR-17-CE17-0015,NAD-HEART,Supplémentation en précurseur du NAD+ pour le traitement de l'insuffisance cardiaque(2017), ANR-08-GENO-0038,REMODEL-SRF,Remodelage des organes creux musculaires et dilatations: établir un lien avec le Facteur de Réponse au Sérum(2008), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM), SIGNALISATION ET PHYSIOPATHOLOGIE CARDIOVASCULAIRE (UMRS1180, LabEx LERMIT), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-IFR140-Institut National de la Santé et de la Recherche Médicale (INSERM), École normale supérieure - Cachan (ENS Cachan)-Centre National de la Recherche Scientifique (CNRS), ANR-17-CE17-0015,NAD-HEART,Supplémentation en précurseur du NAD+ pour le traitement de l’insuffisance cardiaque(2017), DECAUX, Jean-François, Supplémentation en précurseur du NAD+ pour le traitement de l'insuffisance cardiaque - - NAD-HEART2017 - ANR-17-CE17-0015 - AAPG2017 - VALID, Du gène à la physiopathologie, des maladies rares aux maladies communes - Remodelage des organes creux musculaires et dilatations: établir un lien avec le Facteur de Réponse au Sérum - - REMODEL-SRF2008 - ANR-08-GENO-0038 - GENOPAT - VALID
المصدر: Circulation
Circulation, 2018, 137 (21), pp.2256-2273. ⟨10.1161/CIRCULATIONAHA.116.026099⟩
Circulation, American Heart Association, 2018, 137 (21), pp.2256-2273. ⟨10.1161/CIRCULATIONAHA.116.026099⟩مصطلحات موضوعية: 0301 basic medicine, MESH: Niacinamide/analogs & derivatives, Serum Response Factor, MESH: Cytokines/genetics, Cardiomyopathy, MESH: Dietary Supplements, Pyridinium Compounds, Pharmacology, MESH: Acrylamides/therapeutic use, MESH: Myocytes, Cardiac/cytology, AMP-Activated Protein Kinases, [SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, nicotinamide-beta-riboside, MESH: Cardiomyopathy, Dilated/drug therapy, chemistry.chemical_compound, Mice, Piperidines, energy metabolism, Glycolysis, MESH: Animals, MESH: PPAR alpha/metabolism, Myocytes, Cardiac, MESH: Piperidines/therapeutic use, Nicotinamide Phosphoribosyltransferase, Dilated cardiomyopathy, glycolysis, MESH: Myocytes, Cardiac/metabolism, MESH: Phosphotransferases (Alcohol Group Acceptor)/metabolism, Phosphotransferases (Alcohol Group Acceptor), MESH: Heart Failure/prevention & control, Metabolome, Cytokines, MESH: NAD/metabolism, Cardiology and Cardiovascular Medicine, dilated, acetyl coenzyme A, Cardiac function curve, Cardiomyopathy, Dilated, Niacinamide, MESH: Rats, MESH: Mice, Transgenic, Mice, Transgenic, Oxidative phosphorylation, MESH: Serum Response Factor/genetics, Citric Acid, MESH: Metabolome/drug effects, MESH: Nicotinamide Phosphoribosyltransferase/metabolism, 03 medical and health sciences, MESH: Gene Expression Profiling, MESH: Citric Acid/metabolism, Physiology (medical), medicine, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, MESH: Niacinamide/therapeutic use, Animals, MESH: Serum Response Factor/deficiency, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, PPAR alpha, MESH: Myocytes, Cardiac/drug effects, MESH: Mice, Heart Failure, Acrylamides, business.industry, MESH: Phosphotransferases (Alcohol Group Acceptor)/genetics, Gene Expression Profiling, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, MESH: Nicotinamide Phosphoribosyltransferase/genetics, medicine.disease, NAD, Rats, MESH: AMP-Activated Protein Kinases/metabolism, Disease Models, Animal, 030104 developmental biology, chemistry, Heart failure, Nicotinamide riboside, Dietary Supplements, NAD+ kinase, MESH: Cytokines/metabolism, MESH: Disease Models, Animal, business, cardiomyopathy, MESH: Phosphotransferases (Alcohol Group Acceptor)/antagonists & inhibitors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff8c9d79a5527d8a72b3544c248b40d
https://pubmed.ncbi.nlm.nih.gov/29784693 -
4مورد إلكتروني
المصدر: Basse , A L , Nielsen , K N , Karavaeva , I , Ingerslev , L R , Ma , T , Havelund , J F , Nielsen , T S , Frost , M , Peics , J , Dalbram , E , Dall , M , Zierath , J R , Barrès , R , Færgeman , N J , Treebak , J T & Gerhart-Hines , Z 2023 , ' NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner ' , Proceedings of the National Academy of Sciences of the United States of America , vol. 120 , no. 14 , e2220102120 .
مصطلحات الفهرس: Animals, NAD/metabolism, Nicotinamide Phosphoribosyltransferase/genetics, Circadian Rhythm/physiology, Adipose Tissue, Brown/metabolism, Obesity/metabolism, Cytokines/metabolism, article
URL:
https://curis.ku.dk/portal/da/publications/namptdependent-nad-biosynthesis-controls-circadian-metabolism-in-a-tissuespecific-manner(206774ee-4c30-449a-908b-736c34e75b81).html https://doi.org/10.1073/pnas.2220102120 https://curis.ku.dk/ws/files/342093937/pnas.2220102120.pdf -
5مورد إلكتروني
المصدر: Basse , A L , Nielsen , K N , Karavaeva , I , Ingerslev , L R , Ma , T , Havelund , J F , Nielsen , T S , Frost , M , Peics , J , Dalbram , E , Dall , M , Zierath , J R , Barrès , R , Færgeman , N J , Treebak , J T & Gerhart-Hines , Z 2023 , ' NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner ' , Proceedings of the National Academy of Sciences of the United States of America , vol. 120 , no. 14 , e2220102120 .
مصطلحات الفهرس: Animals, NAD/metabolism, Nicotinamide Phosphoribosyltransferase/genetics, Circadian Rhythm/physiology, Adipose Tissue, Brown/metabolism, Obesity/metabolism, Cytokines/metabolism, article
URL:
https://curis.ku.dk/portal/da/publications/namptdependent-nad-biosynthesis-controls-circadian-metabolism-in-a-tissuespecific-manner(206774ee-4c30-449a-908b-736c34e75b81).html https://doi.org/10.1073/pnas.2220102120 https://curis.ku.dk/ws/files/342093937/pnas.2220102120.pdf -
6مورد إلكتروني
المصدر: Nature vol.591 (2021) nr.7849 p.281-287 [ISSN 0028-0836]
مصطلحات الفهرس: Animals, Cell Proliferation, Disease Models, Animal, Humans, Macrophages/cytology, Male, Matrix Metalloproteinase 9/genetics, Mice, Mice, Inbred C57BL, Muscle, Skeletal/cytology, Myoblasts/cytology, Nicotinamide Phosphoribosyltransferase/genetics, PAX7 Transcription Factor/metabolism, RNA-Seq, Receptors, CCR5/genetics, Regeneration/physiology, Single-Cell Analysis, Stem Cell Niche, Zebrafish/immunology, Artikel, Article
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7مورد إلكتروني
المصدر: Nature vol.591 (2021) nr.7849 p.281-287 [ISSN 0028-0836]
مصطلحات الفهرس: Animals, Cell Proliferation, Disease Models, Animal, Humans, Macrophages/cytology, Male, Matrix Metalloproteinase 9/genetics, Mice, Mice, Inbred C57BL, Muscle, Skeletal/cytology, Myoblasts/cytology, Nicotinamide Phosphoribosyltransferase/genetics, PAX7 Transcription Factor/metabolism, RNA-Seq, Receptors, CCR5/genetics, Regeneration/physiology, Single-Cell Analysis, Stem Cell Niche, Zebrafish/immunology, Artikel, Article