-
1
المؤلفون: James E. Vath, Thomas Edward Hughes, Margaret Wyman, Niel C. Hoglen, Bryan Burkey, Philip Inskeep
المصدر: Journal of Pharmacology and Experimental Therapeutics. 365:301-313
مصطلحات موضوعية: Male, 0301 basic medicine, Drug, Morpholines, medicine.medical_treatment, media_common.quotation_subject, 030209 endocrinology & metabolism, Pharmacology, Aminopeptidases, Mice, 03 medical and health sciences, chemistry.chemical_compound, Dogs, 0302 clinical medicine, Cyclohexanes, In vivo, Diabetes mellitus, medicine, Animals, Humans, Hypoglycemic Agents, Tissue Distribution, Obesity, Enzyme Inhibitors, Adverse effect, Blood Coagulation, media_common, business.industry, Insulin, Beloranib, Metalloendopeptidases, Hep G2 Cells, medicine.disease, In vitro, Rats, Mice, Inbred C57BL, 030104 developmental biology, chemistry, Cinnamates, Pharmacodynamics, Azetidines, Epoxy Compounds, Molecular Medicine, Female, Safety, business, Sesquiterpenes
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75178b1c01e7f175da71410ab91ce16f
https://doi.org/10.1124/jpet.117.246272 -
2
المؤلفون: Niel C. Hoglen, Scott A. Mobley, Glenn Sipes, John Michael Sauer, R. Clark Lantz, David L. Earnest, Robert S. McCuskey, Edward A. Abril
المصدر: Liver. 17:157-165
مصطلحات موضوعية: Male, Vitamin, medicine.medical_specialty, Kupffer Cells, Biology, Peripheral blood mononuclear cell, Dinoprostone, Monocytes, Rats, Sprague-Dawley, chemistry.chemical_compound, Phagocytosis, Superoxides, Internal medicine, medicine, Animals, All trans retinol, Vitamin A, Cells, Cultured, Liver injury, Hepatology, Tumor Necrosis Factor-alpha, Monocyte, Kupffer cell, Zymosan, Retinol, medicine.disease, Rats, medicine.anatomical_structure, Endocrinology, chemistry, Luminescent Measurements, Reactive Oxygen Species
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8bb7e77b238bb2ff0f43b9b08419f9d
https://doi.org/10.1111/j.1600-0676.1997.tb00799.x -
3
المؤلفون: Karen L. Valentino, Ronald W. Busuttil, Douglas G. Farmer, Marian Kaldas, Charles Lassman, Niel C. Hoglen, Jerzy W. Kupiec-Weglinski, Masamichi Katori, Xiu-Da Shen, Dean M. Anselmo
المصدر: Liver Transplantation. 13:361-366
مصطلحات موضوعية: Male, medicine.medical_specialty, Necrosis, medicine.medical_treatment, Organ Preservation Solutions, Cold storage, Apoptosis, Liver transplantation, Rats, Sprague-Dawley, Internal medicine, medicine, Animals, Viaspan, Enzyme Inhibitors, Pentanoic Acids, Liver injury, Transplantation, TUNEL assay, Hepatology, business.industry, Temperature, Organ Preservation, medicine.disease, Caspase Inhibitors, Rats, Treatment Outcome, medicine.anatomical_structure, Endocrinology, Reperfusion Injury, Hepatocyte, Models, Animal, Immunology, Surgery, medicine.symptom, business, Reperfusion injury
-
4
المؤلفون: Kevin J. Tomaselli, Julia Herrmann, Robert O. Sayers, Joe C. Wu, Lalitha Kodandapani, Kathy G. Jahangiri, Craig D. Fisher, David T. Winn, Edward D. Robinson, Steven P. Meduna, Robert J. Ternansky, Pauline Yeo, Karen L. Valentino, Jose-Luis Diaz, Vincent J. Kalish, Steven D. Linton, Kristen Sebring, Robert A. Armstrong, Joseph F. Krebs, Niel C. Hoglen, Alfred P. Spada, Brad P. Hirakawa, Ning Chen, Brett R. Ullman, Brett Weylan Ching, Cheng-zhi Zhang, Xu Bai, Xin Gu, Kip Nalley, Long-Shiuh Chen, Patricia L. Gladstone, Jeff McQuiston, Teresa Aja, Todd Groessl, Donald S. Karanewsky, Suzanne Weeks, Lawrence C. Fritz, Patricia C. Contreras
المصدر: Journal of Medicinal Chemistry. 48:6779-6782
مصطلحات موضوعية: Adult, Biological Availability, Phases of clinical research, Apoptosis, Pharmacology, Jurkat Cells, Mice, Structure-Activity Relationship, Liver disease, Pharmacokinetics, In vivo, Drug Discovery, medicine, Animals, Humans, Aspartate Aminotransferases, Pentanoic Acids, Caspase, Liver injury, Cholestasis, Clinical Trials, Phase I as Topic, biology, Caspase 3, Chemistry, Liver Diseases, Alanine Transaminase, Hepatitis C, Chronic, medicine.disease, Caspase Inhibitors, In vitro, Rats, Liver, Biochemistry, Enzyme inhibitor, Hepatocytes, biology.protein, Molecular Medicine, Half-Life
-
5
المؤلفون: Niel C. Hoglen, Patricia C. Contreras, Brad P. Hirakawa, Long-Shiuh Chen, Todd Groessl, Craig D. Fisher
المصدر: Journal of Pharmacology and Experimental Therapeutics. 309:634-640
مصطلحات موضوعية: Male, Pharmacology, Rats, Sprague-Dawley, Mice, Liver disease, Pharmacokinetics, In vivo, Oral administration, medicine, Animals, Potency, Enzyme Inhibitors, Pentanoic Acids, Caspase, Liver injury, Mice, Inbred BALB C, biology, business.industry, medicine.disease, Caspase Inhibitors, Rats, Apoptosis, Models, Animal, biology.protein, Molecular Medicine, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78cd6072fda815132c80b024022dc888
https://doi.org/10.1124/jpet.103.062034 -
6
المؤلفون: L Gunawardhana, Niel C. Hoglen, I. G. Sipes, Husam S. Younis, R. K. Kuester
المصدر: Toxicology and Applied Pharmacology. 163:141-148
مصطلحات موضوعية: Male, medicine.medical_specialty, Time Factors, Kupffer Cells, Gadolinium, Cell Separation, Oxidative phosphorylation, Chlorobenzenes, Toxicology, medicine.disease_cause, Rats, Sprague-Dawley, Lipid peroxidation, chemistry.chemical_compound, Internal medicine, medicine, Animals, Bile, Pharmacology, Liver injury, Ethane, Glutathione Disulfide, Glutathione, medicine.disease, Rats, Inbred F344, Rats, Oxidative Stress, medicine.anatomical_structure, Endocrinology, Breath Tests, Liver, chemistry, Hepatocyte, Toxicity, Glutathione disulfide, Biomarkers, Oxidative stress
-
7
المؤلفون: R. Clark Lantz, Niel C. Hoglen, I. Glenn Sipes, Husam S. Younis, L Gunawardhana, Dylan P. Hartley
المصدر: Toxicological Sciences. 46:376-385
مصطلحات موضوعية: Male, Insecticides, medicine.medical_specialty, Kupffer Cells, Anti-Inflammatory Agents, Gadolinium, Cysteine Proteinase Inhibitors, Chlorobenzenes, Toxicology, Lipid peroxidation, Necrosis, chemistry.chemical_compound, Internal medicine, medicine, Animals, chemistry.chemical_classification, Aldehydes, Reactive oxygen species, Superoxide, Kupffer cell, Alanine Transaminase, Immunohistochemistry, Rats, Inbred F344, Rats, medicine.anatomical_structure, Endocrinology, Liver, Mechanism of action, chemistry, Biochemistry, Vacuoles, Toxicity, Lipid Peroxidation, medicine.symptom, Reactive Oxygen Species, Corn oil
-
8
المؤلفون: Niel C. Hoglen, Husam S. Younis, J M Sauer, L E Twerdok, I. G. Sipes, M J Miller, J L Hensel, D R Steup, S P Regan, S J Waterman
المصدر: Toxicological Sciences. 46:176-184
مصطلحات موضوعية: medicine.medical_specialty, Necrosis, Kupffer Cells, Vacuole, Biology, Toxicology, Leukotriene B4, Nitric oxide, Rats, Sprague-Dawley, Leukocyte Count, chemistry.chemical_compound, Phagocytosis, Species Specificity, Superoxides, Internal medicine, medicine, Animals, Nitrites, Tumor Necrosis Factor-alpha, Superoxide, Body Weight, Kupffer cell, medicine.disease, Rats, Inbred F344, Enzymes, Rats, Endocrinology, medicine.anatomical_structure, Liver, Biochemistry, chemistry, Paraffin, Granuloma, Toxicity, Female, Tumor necrosis factor alpha, medicine.symptom
-
9
المؤلفون: Niel C. Hoglen, Husam S. Younis, Dylan P. Hartley, Lhanoo Gunawardhana, R. Clark Lantz, I. Glenn Sipes
المصدر: Toxicological Sciences. 46:376-385
مصطلحات موضوعية: Toxicology
-
10
المصدر: Chemical Research in Toxicology. 10:401-407
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Nitrates, Chemistry, Diastereomer, General Medicine, Buffer solution, Toxicology, Medicinal chemistry, Quinone, chemistry.chemical_compound, Potassium phosphate, Molsidomine, Nitration, Vitamin E, Organic chemistry, Spectrophotometry, Ultraviolet, Methanol, Acetonitrile, Oxidation-Reduction, Peroxynitrite