المؤلفون: Barbara H Stokes, Satish K Dhingra, Kelly Rubiano, Sachel Mok, Judith Straimer, Nina F Gnädig, Ioanna Deni, Kyra A Schindler, Jade R Bath, Kurt E Ward, Josefine Striepen, Tomas Yeo, Leila S Ross, Eric Legrand, Frédéric Ariey, Clark H Cunningham, Issa M Souleymane, Adama Gansané, Romaric Nzoumbou-Boko, Claudette Ndayikunda, Abdunoor M Kabanywanyi, Aline Uwimana, Samuel J Smith, Olimatou Kolley, Mathieu Ndounga, Marian Warsame, Rithea Leang, François Nosten, Timothy JC Anderson, Philip J Rosenthal, Didier Ménard, David A Fidock

المصدر: eLife, Vol 10 (2021)

مصطلحات موضوعية: Plasmodium falciparum, malaria, artemisinin resistance, CRISPR/Cas9, ring-stage survival, fitness, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/66277; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/3358baaa1cad40f3a6991b0106481a5a

المؤلفون: Nina F Gnädig, Barbara H Stokes, Rachel L Edwards, Gavreel F Kalantarov, Kim C Heimsch, Michal Kuderjavy, Audrey Crane, Marcus C S Lee, Judith Straimer, Katja Becker, Ilya N Trakht, Audrey R Odom John, Sachel Mok, David A Fidock

المصدر: PLoS Pathogens, Vol 16, Iss 4, p e1008482 (2020)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/63f0cf7a413247b28ca9b575fa65febb

المؤلفون: Stanislaw J Gabryszewski, Satish K Dhingra, Jill M Combrinck, Ian A Lewis, Paul S Callaghan, Matthew R Hassett, Amila Siriwardana, Philipp P Henrich, Andrew H Lee, Nina F Gnädig, Lise Musset, Manuel Llinás, Timothy J Egan, Paul D Roepe, David A Fidock

المصدر: PLoS Pathogens, Vol 12, Iss 11, p e1005976 (2016)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5104409?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/bab670c229784bbdbbf53c730e617d2b

المؤلفون: Amélie Le Bihan, Ruben de Kanter, Iñigo Angulo-Barturen, Christoph Binkert, Christoph Boss, Reto Brun, Ralf Brunner, Stephan Buchmann, Jeremy Burrows, Koen J Dechering, Michael Delves, Sonja Ewerling, Santiago Ferrer, Christoph Fischli, Francisco Javier Gamo-Benito, Nina F Gnädig, Bibia Heidmann, María Belén Jiménez-Díaz, Didier Leroy, Maria Santos Martínez, Solange Meyer, Joerg J Moehrle, Caroline L Ng, Rintis Noviyanti, Andrea Ruecker, Laura María Sanz, Robert W Sauerwein, Christian Scheurer, Sarah Schleiferboeck, Robert Sinden, Christopher Snyder, Judith Straimer, Grennady Wirjanata, Jutta Marfurt, Ric N Price, Thomas Weller, Walter Fischli, David A Fidock, Martine Clozel, Sergio Wittlin

المصدر: PLoS Medicine, Vol 13, Iss 10, p e1002138 (2016)

مصطلحات موضوعية: Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

URL الوصول: https://doaj.org/article/c760742987d34859b710bc8b89e29d3c

المؤلفون: Antonio V Bordería, Ofer Isakov, Gonzalo Moratorio, Rasmus Henningsson, Sonia Agüera-González, Lindsey Organtini, Nina F Gnädig, Hervé Blanc, Andrés Alcover, Susan Hafenstein, Magnus Fontes, Noam Shomron, Marco Vignuzzi

المصدر: PLoS Pathogens, Vol 11, Iss 5, p e1004838 (2015)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4420505?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/12bf3c4d8949455489cae1b59f70dc80

المؤلفون: Laura I Levi, Nina F Gnädig, Stéphanie Beaucourt, Malia J McPherson, Bruno Baron, Jamie J Arnold, Marco Vignuzzi

المصدر: PLoS Pathogens, Vol 6, Iss 10, p e1001163 (2010)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC2965762?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/b8763665235e41dca5c8d5331893504c

المؤلفون: Sachel Mok, David A. Fidock, Barbara H. Stokes, Nina F. Gnädig, Chanaki Amaratunga, Zbynek Bozdech, Erik L. Allman, Andrew R. Bottrill, Jaishree Tripathi, Lev Solyakov, Tomas Yeo, Leila S. Ross, Manuel Llinás, Rick M. Fairhurst, Andrew B. Tobin

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Proteomics, Erythrocytes, Science, 030106 microbiology, Mutant, Plasmodium falciparum, Drug Resistance, Protozoan Proteins, General Physics and Astronomy, Biology, Protein degradation, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Antimalarials, parasitic diseases, medicine, Humans, Metabolomics, Artemisinin, Atovaquone, Mutation, Multidisciplinary, Models, Genetic, Gene Expression Profiling, General Chemistry, Cell Cycle Checkpoints, biology.organism_classification, Virology, Artemisinins, Mitochondria, Parasite biology, 030104 developmental biology, Unfolded protein response, Parasite development, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe06626fa6cba8e7742fa6fc309c6721
https://doaj.org/article/bc2f468af6fd4c64bd1c2706fa3f4ce6

المؤلفون: Nina F. Gnädig, Françoise Benoit-Vical, Romain Coppée, Jérôme Clain, David A. Fidock, Karamoko Niaré, Jean-Michel Augereau, Barbara H. Stokes, Lucie Paloque

المساهمون: Laboratoire de chimie de coordination (LCC), Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), New Antimalarial Molecules and Pharmacological Approaches (ERL1289), Centre d'investigation clinique de Toulouse (CIC 1436), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Pôle Santé publique et médecine publique [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Université Toulouse III - Paul Sabatier (UT3), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Institut de pharmacologie et de biologie structurale (IPBS), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Mère et enfant en milieu tropical : pathogènes, système de santé et transition épidémiologique (MERIT - UMR_D 261), Institut de Recherche pour le Développement (IRD)-Université Paris Cité (UPCité), Columbia University Irving Medical Center (CUIMC), Malaria Research and Training Center [Bamako, Mali], Université de Bamako, AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre National de la Recherche Scientifique (CNRS), NIH (R01 AI109023), WorldWide Antimalarial Resistance Network (WWARN), ANR-17-CE15-0013,PlasmoPrim,Elucider les mécanismes d'action de deux agents redox antipaludiques aux propriétés gametocytocides et bloquant la transmission -- de la levure aux parasites du paludisme(2017), Institut de Chimie de Toulouse (ICT-FR 2599), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Pôle Santé publique et médecine publique [CHU Toulouse], Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Mère et enfant en milieu tropical : pathogènes, système de santé et transition épidémiologique (MERIT - UMR_D 216), Gulli, Marie-Hélène, Elucider les mécanismes d'action de deux agents redox antipaludiques aux propriétés gametocytocides et bloquant la transmission -- de la levure aux parasites du paludisme - - PlasmoPrim2017 - ANR-17-CE15-0013 - AAPG2017 - VALID

المصدر: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 2022, 66 (1), pp.e01320-21. ⟨10.1128/AAC.01320-21⟩

مصطلحات موضوعية: medicine.medical_treatment, Plasmodium falciparum, Drug Resistance, Protozoan Proteins, Dihydroartemisinin, medicine.disease_cause, Epidemiology and Surveillance, Antimalarials, parasitic diseases, medicine, Coding region, CRISPR, [CHIM.COOR]Chemical Sciences/Coordination chemistry, Pharmacology (medical), Artemisinin, BTB/POZ domain, Gene, Pharmacology, Mutation, biology, K13 mutation, [CHIM.COOR] Chemical Sciences/Coordination chemistry, Editor's Pick, biology.organism_classification, Virology, Artemisinins, Malaria, Infectious Diseases, Artemisinin resistance, BTB-POZ Domain, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa70ff64915a7d8f74890e13f65a4174
https://doi.org/10.1128/aac.01320-21

المؤلفون: Sachel Mok, Adama Gansané, Rithea Leang, Clark H. Cunningham, Romaric Nzoumbou-Boko, David A. Fidock, Aline Uwimana, Ioanna Deni, Nina F. Gnädig, Barbara H. Stokes, Marian Warsame, Kelly Rubiano, Leila S. Ross, Olimatou Kolley, Kurt E. Ward, Issa M. Souleymane, Eric Legrand, Frédéric Ariey, Philip J. Rosenthal, Josefine Striepen, Samuel J. Smith, Abdunoor M. Kabanywanyi, Judith Straimer, Jade Bath, Kyra A Schindler, Didier Menard, Mathieu Ndounga, Tim J. Anderson, François Nosten, Claudette Ndayikunda, Tomas Yeo, Satish K. Dhingra

المساهمون: Columbia University Irving Medical Center (CUIMC), Washington University in Saint Louis (WUSTL), Génétique du paludisme et résistance - Malaria Genetics and Resistance, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), INSERM U1201 (U1201), Unité de Biologie des interactions hôte-parasite (U1201), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Programme National de Lutte Contre le Paludisme au Tchad, Centre National de Recherche et de Formation sur le Paludisme [Ouagadougou, Burkina Faso] (CNRFP), Laboratoire de parasitologie - Laboratory of Parasitology [Bangui], Institut Pasteur de Bangui, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Centre Hospitalo-Universitaire de Kamenge [Bujumbura, Burundi] (CHUK), Ifakara Health Institute [Dar-es-Salaam, Tanzania], Rwanda Biomedical Center (RBC), National Malaria Control Programme [Sierra Leone], National Malaria Control Programme [Banjul, Gambia], Programme National de Lutte Contre le Paludisme [Brazzaville, Democratic Republic of the Congo], University of Gothenburg (GU), National Center for Parasitology, Entomology and Malaria Control [Phnom Penh, Cambodia] (CNM), Mahidol University [Bangkok], Texas Biomedical Research Institute [San Antonio, TX], University of California [San Francisco] (UCSF), University of California, Columbia University Medical Center (CUMC), Columbia University [New York], DAF gratefully acknowledges the US National Institutes of Health (R01 AI109023), the Department of Defense (W81XWH1910086) and the Bill & Melinda Gates Foundation (OPP1201387) for their financial support. BHS was funded in part by T32 AI106711 (PD: D. Fidock). SM is a recipient of a Human Frontiers of Science Program Long-Term Fellowship. CHC was supported in part by the NIH (R01 AI121558, PI: Jonathan Juliano). FN is supported by the Wellcome Trust of Great Britain (Grant ID: 106698). TJCA acknowledges funding support from the NIH (R37 AI048071). DAF and DM gratefully acknowledge the World Health Organization for their funding., Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Biologie des Interactions Hôte-Parasite - Biology of Host-Parasite Interactions, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), University of California [San Francisco] (UC San Francisco), University of California (UC), Menard, Didier

المصدر: eLife, Vol 10 (2021)
eLife
eLife, eLife Sciences Publication, 2021, 10, pp.e66277. ⟨10.7554/eLife.66277⟩
eLife, 2021, 10, pp.e66277. ⟨10.7554/eLife.66277⟩

مصطلحات موضوعية: 0301 basic medicine, QH301-705.5, infectious disease, Science, 030106 microbiology, Plasmodium falciparum, malaria, global health, P. falciparum, Biology, artemisinin resistance, medicine.disease_cause, Southeast asian, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, parasitic diseases, medicine, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, Artemisinin, Biology (General), Genotyping, CRISPR/Cas9, Genetics, Microbiology and Infectious Disease, Mutation, General Immunology and Microbiology, General Neuroscience, Point mutation, microbiology, General Medicine, medicine.disease, biology.organism_classification, 3. Good health, fitness, Epidemiology and Global Health, 030104 developmental biology, Infectious disease (medical specialty), [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Medicine, epidemiology, ring-stage survival, [SDV.MP.PAR] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, Malaria, Research Article, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d4652f8546d77e0464272dc94dc4b6
https://ora.ox.ac.uk/objects/uuid:24d02c06-c99a-469c-92f8-1d3ccb074394

المؤلفون: Jennifer A. Yang, Bing Yu Zou, Frances Rocamora, Edgar Vigil, Prianka Kumar, Nina F. Gnädig, Alan F. Cowman, David A. Fidock, Roy Williams, Trevor Johnson, Madeline R. Luth, Danushka S. Marapana, Dylan Hutson, Marcus C. S. Lee, Tilla S. Worgall, Jianbo Huang, Gregory M. Goldgof, Gregory LaMonte, T. R. Santha Kumar, Jennifer K. Thompson, Timothy J. Egan, Roxanne Mohunlal, Sabine Ottilie, Dionicio Siegel, Elizabeth A. Winzeler, Andrea L. Cheung

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature communications, vol 11, iss 1

مصطلحات موضوعية: 0301 basic medicine, ved/biology.organism_classification_rank.species, Protozoan Proteins, General Physics and Astronomy, Synthetic lethality, Endoplasmic Reticulum, Plasmodium, Mass Spectrometry, chemistry.chemical_compound, 2.1 Biological and endogenous factors, 2.2 Factors relating to the physical environment, Aetiology, lcsh:Science, Chromatography, High Pressure Liquid, Chromatography, Multidisciplinary, Secretory Pathway, biology, Brefeldin A, Cell biology, Infectious Diseases, 5.1 Pharmaceuticals, High Pressure Liquid, HIV/AIDS, Development of treatments and therapeutic interventions, medicine.symptom, Infection, Science, 030106 microbiology, Saccharomyces cerevisiae, Plasmodium falciparum, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Antimalarials, Inhibitory Concentration 50, Rare Diseases, Target identification, parasitic diseases, medicine, Secretion, Model organism, Gene, Secretory pathway, ved/biology, Endoplasmic reticulum, Autophagy, General Chemistry, biology.organism_classification, Malaria, Vector-Borne Diseases, Good Health and Well Being, 030104 developmental biology, chemistry, Mechanism of action, Pyrazoles, lcsh:Q

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b18290350407667761814a3f37b90a3
https://doaj.org/article/30325ebc8f1440eb95a7ef787cbdca69