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1
المؤلفون: Matthew D. Hill, Haiquan Fang, Derek Norris, George V. Delucca, Hong Huang, Mikkel DeBenedetto, Claude Quesnelle, William D. Schmitz, John S. Tokarski, Steven Sheriff, Chunhong Yan, Caroline Fanslau, Zuzana Haarhoff, Christine Huang, Melissa Kramer, Shilpa Madari, Krista Menard, Laura Monereau, John Morrison, Nirmala Raghavan, Eric E. Shields, Jean Simmermacher-Mayer, Michael Sinz, Ching Kim Tye, Richard Westhouse, Chunshan Xie, Haiying Zhang, Lisa Zhang, Tatyana Zvyaga, Francis Lee, Ashvinikumar V. Gavai, Andrew P. Degnan
المصدر: ACS Medicinal Chemistry Letters. 13:1165-1171
مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry
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2
المؤلفون: Ching Kim Tye, Chunhong Yan, Sarah C. Traeger, Wayne Vaccaro, Yingru Zhang, Gerry Everlof, Jianqing Li, Henry Yip, Peng Li, John T. Hunt, Michael A. Poss, Gregory D. Vite, Mussari Christopher P, Steven Sheriff, Asoka Ranasinghe, Haiying Zhang, Richard A. Westhouse, Dharmpal S. Dodd, Richard Rampulla, Zheng Yang, Frank Marsilio, Derek J. Norris, Wen-Ching Han, Tram N. Huynh, Yufen Zhao, Patrice Gill, Nirmala Raghavan, Lalgudi S. Harikrishnan, Ashvinikumar V. Gavai, Susan Wee, John S. Tokarski, Dauh-Rurng Wu, Arvind Mathur, Mei-Li Wen, Huiping Zhang, David R. Tortolani, George V. Delucca, Krista Menard, Francis Y. Lee, Claude A. Quesnelle, Dawn Sun, Vijay T. Ahuja, Daniel O'malley, Christine Huang, Muthoni G. Kamau
المصدر: Journal of Medicinal Chemistry. 64:14247-14265
مصطلحات موضوعية: Drug, Proline, Phenylalanine, media_common.quotation_subject, Carbazoles, Administration, Oral, Antineoplastic Agents, Cell Cycle Proteins, Computational biology, BET inhibitor, Structure-Activity Relationship, Pharmacokinetics, In vivo, Drug Discovery, Transcriptional regulation, Humans, Potency, media_common, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Tryptophan, Signal transducing adaptor protein, Bromodomain, Molecular Medicine, Transcription Factors
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3
المؤلفون: Nirmala Raghavan, S. Panboli
المصدر: Indian Journal of Public Health Research & Development. 10:819
مصطلحات موضوعية: Coping (psychology), media_common.quotation_subject, Emotion focused, Emotional intelligence, Human life, Applied psychology, Public Health, Environmental and Occupational Health, Positive coping, Research studies, Problem focused, Anger, media_common, Mathematics
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bcf411a6c05ab3026bd7e0ab81590316
https://doi.org/10.5958/0976-5506.2019.01993.4 -
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المؤلفون: Richard A. Westhouse, Nirmala Raghavan, Donglu Zhang, Weiping Zhao, Alban Allentoff, Ashok Kumar Gupta, W. Griffith Humphreys, Jinping Gan, Guoxiang Shen, Yueping Zhang, Robert M. Borzilleri, Oliver P. Flint, Jonathan L. Josephs, Punit Marathe, Janet Caceres-Cortes, Lifei Wang
المصدر: Chemical Research in Toxicology. 25:556-571
مصطلحات موضوعية: Male, medicine.medical_specialty, Necrosis, Pyridines, Pharmacology, Toxicology, Cell Line, Rats, Sprague-Dawley, Mice, In vivo, Oral administration, Internal medicine, Adrenal Glands, medicine, Animals, Humans, Tissue Distribution, Carbon Radioisotopes, Cholesterol Side-Chain Cleavage Enzyme, Protein Kinase Inhibitors, biology, Adrenal gland, Adrenal cortex, Cytochrome P450, General Medicine, Metabolism, Rats, Endocrinology, medicine.anatomical_structure, Toxicity, biology.protein, medicine.symptom
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5A low flow ionization technique to integrate quantitative and qualitative small molecule bioanalysis
المصدر: International Journal of Mass Spectrometry. 301:127-135
مصطلحات موضوعية: Bioanalysis, Chromatography, Chemistry, Condensed Matter Physics, Mass spectrometry, Small molecule, High-performance liquid chromatography, Quantitative determination, Highly sensitive, Human plasma, Ionization, Physical and Theoretical Chemistry, Instrumentation, Spectroscopy
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6
المؤلفون: Dauh-Rurng Wu, Zheng Yang, Steven Sheriff, Muthoni G. Kamau, Lalgudi S. Harikrishnan, Dharmpal S. Dodd, Henry Yip, Christine Huang, Yingru Zhang, Yufen Zhao, Jianqing Li, Richard A. Westhouse, Richard Rampulla, Ashvinikumar V. Gavai, Haiying Zhang, Susan Wee, Dawn Sun, Gerry Everlof, Tram N. Huynh, Ching Su, Derek J. Norris, Arvind Mathur, Wayne Vaccaro, Peng Li, Huiping Zhang, Gregory D. Vite, Mussari Christopher P, John T. Hunt, Asoka Ranasinghe, David R. Tortolani, Nirmala Raghavan, Celia D’Arienzo, Daniel O'malley, Vijay T. Ahuja, Patrice Gill, Lisa Zhang, Claude A. Quesnelle, Tokarski John S, Michael A. Poss
المصدر: Cancer Research. 78:5789-5789
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Thermal shift assay, BRD4, Oncogene, Chemistry, Cancer, medicine.disease, Bromodomain, BET inhibitor, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, In vivo, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ad3948219544cdcb29d5e3baea4000aa
https://doi.org/10.1158/1538-7445.am2018-5789 -
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المؤلفون: Lifei, Wang, Donglu, Zhang, Nirmala, Raghavan, Ming, Yao, Li, Ma, Charles E, Frost, Charles A, Frost, Brad D, Maxwell, Shiang-yuan, Chen, Kan, He, Theunis C, Goosen, W Griffith, Humphreys, Scott J, Grossman
المصدر: Drug Metabolism and Disposition. 38:448-458
مصطلحات موضوعية: Aging, Pyridones, Drug Evaluation, Preclinical, Pharmaceutical Science, Pharmacology, Hydroxylation, CYP2J2, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Microsomes, medicine, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme Inhibitors, Humans, Drug Interactions, RNA, Messenger, Cells, Cultured, biology, CYP3A4, CYP1A2, Anticoagulants, Cytochrome P450, Recombinant Proteins, Isoenzymes, Kinetics, Biochemistry, chemistry, Organ Specificity, Hepatocytes, biology.protein, Microsome, Cytochrome P-450 CYP3A Inhibitors, Pyrazoles, Metabolic Detoxication, Phase I, Apixaban, Factor Xa Inhibitors, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6977bb8aff132b87ff4229b31e388c
https://doi.org/10.1124/dmd.109.029694 -
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المؤلفون: Kan He, Nirmala Raghavan, Lifei Wang, Robert M. Knabb, Joseph M. Luettgen, W. Griffith Humphreys, Donglu Zhang, Donald J. P. Pinto
المصدر: Drug Metabolism and Disposition. 37:802-808
مصطلحات موضوعية: medicine.drug_mechanism_of_action, Pyridones, Metabolite, Factor Xa Inhibitor, Pharmaceutical Science, Estrone, Pharmacology, Methylation, Mass Spectrometry, chemistry.chemical_compound, Sulfation, Species Specificity, medicine, Animals, Humans, Enzyme Inhibitors, Sulfate, Biotransformation, Chromatography, High Pressure Liquid, chemistry.chemical_classification, biology, Sulfates, Chemistry, Cytochrome P450, Enzyme, Biocatalysis, biology.protein, Pyrazoles, Apixaban, Sulfotransferases, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba26d18b217bbb361455fde1f131cb60
https://doi.org/10.1124/dmd.108.025593 -
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المؤلفون: Yongjun Xue, Donglu Zhang, J. Billy Akinsanya, Nirmala Raghavan
المصدر: Rapid Communications in Mass Spectrometry. 22:109-120
مصطلحات موضوعية: Anomer, Chromatography, Organic Chemistry, Selected reaction monitoring, Glucuronic acid, High-performance liquid chromatography, Analytical Chemistry, Standard curve, chemistry.chemical_compound, Aglycone, chemistry, Moiety, Glucuronide, Spectroscopy
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10
المؤلفون: Lloyd Lecureux, Samuel J. Bonacorsi, Robert M. Knabb, Kan He, Patrick Y.S. Lam, Mimi Quan, Gary L. Skiles, Laura M. Patrone, Nirmala Raghavan, Haiying Zhang, Shiang-Yuan Chen, Donglu Zhang
المصدر: Drug Metabolism and Disposition. 36:303-315
مصطلحات موضوعية: Male, medicine.medical_specialty, Metabolite, Pharmaceutical Science, Biology, Reductase, Benzamidine, Rats, Sprague-Dawley, Feces, chemistry.chemical_compound, Dogs, Pharmacokinetics, In vivo, Internal medicine, medicine, Animals, Bile, Biotransformation, Cells, Cultured, Pharmacology, Anticoagulants, Primary metabolite, Isoxazoles, Metabolism, Benzamidines, Rats, Metabolic pathway, Endocrinology, Liver, chemistry, Hepatocytes, Pyrazoles, Oxidation-Reduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2359f882100949bd6ec236be087b2f59
https://doi.org/10.1124/dmd.107.018416