المؤلفون: Shokat, Kevan, Novotny, CJ, Pollari, S, Park, JH, Lemmon, MA, Shen, W, Shokat, KM

URL الوصول: https://escholarship.org/uc/item/8k2990xj

المؤلفون: Shokat, Kevan, Rodrik-Outmezguine, VS, Okaniwa, M, Yao, Z, Novotny, CJ, McWhirter, C, Banaji, A, Won, H, Wong, W, Berger, M, de, E

URL الوصول: https://escholarship.org/uc/item/5jc6g00z

المؤلفون: Shokat, Kevan, Lazarus, MB, Novotny, CJ, Shokat, KM

URL الوصول: https://escholarship.org/uc/item/3268q4d8

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المؤلفون: Yang G; University of Sydney, School of life and Environmental Sciences, Charles Perkins Centre, Sydney, New South Wales 2006, Australia., Francis D; University of Sydney, School of life and Environmental Sciences, Charles Perkins Centre, Sydney, New South Wales 2006, Australia., Krycer JR; University of Sydney, School of life and Environmental Sciences, Charles Perkins Centre, Sydney, New South Wales 2006, Australia., Larance M; University of Sydney, School of life and Environmental Sciences, Charles Perkins Centre, Sydney, New South Wales 2006, Australia., Zhang Z; Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, University of California, San Francisco, 600 16th Street, San Francisco, CA 94143, USA., Novotny CJ; Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, University of California, San Francisco, 600 16th Street, San Francisco, CA 94143, USA., Diaz-Vegas A; University of Sydney, School of life and Environmental Sciences, Charles Perkins Centre, Sydney, New South Wales 2006, Australia., Shokat KM; Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, University of California, San Francisco, 600 16th Street, San Francisco, CA 94143, USA., James DE; University of Sydney, School of life and Environmental Sciences, Charles Perkins Centre, Sydney, New South Wales 2006, Australia.; University of Sydney, Sydney Medical School, Sydney, New South Wales 2006, Australia.

المصدر: Science signaling [Sci Signal] 2021 Sep 21; Vol. 14 (701), pp. eabe0161. Date of Electronic Publication: 2021 Sep 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

مواضيع طبية MeSH: Sirolimus*/pharmacology , TOR Serine-Threonine Kinases*, Biology ; Mechanistic Target of Rapamycin Complex 1

المؤلفون: Morisot N; Department of Neurology, University of California, San Francisco, CA, USA., Novotny CJ; Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA., Shokat KM; Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA., Ron D; Department of Neurology, University of California, San Francisco, CA, USA.

المصدر: Addiction biology [Addict Biol] 2018 Mar; Vol. 23 (2), pp. 713-722. Date of Electronic Publication: 2017 Jul 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 9604935 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1369-1600 (Electronic) Linking ISSN: 13556215 NLM ISO Abbreviation: Addict Biol Subsets: MEDLINE

مواضيع طبية MeSH: Benzoxazoles/*pharmacology , Central Nervous System Depressants/*administration & dosage , Ethanol/*administration & dosage , Mechanistic Target of Rapamycin Complex 1/*antagonists & inhibitors , Oxazoles/*pharmacology , Protein Kinase Inhibitors/*pharmacology , Pyrimidines/*pharmacology , Sirolimus/*analogs & derivatives , Sirolimus/*pharmacology, Alcohol Drinking ; Animals ; Behavior, Animal/drug effects ; Binge Drinking ; Choice Behavior/drug effects ; Mice ; Reward

المؤلفون: Novotny CJ; Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California San Francisco , San Francisco, California 94158, United States., Hamilton GL; Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California San Francisco , San Francisco, California 94158, United States., McCormick F; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc. , Frederick, Maryland 21701, United States.; Diller Family Comprehensive Cancer Center, University of California , San Francisco, California 94158, United States., Shokat KM; Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California San Francisco , San Francisco, California 94158, United States.

المصدر: ACS chemical biology [ACS Chem Biol] 2017 Jul 21; Vol. 12 (7), pp. 1956-1962. Date of Electronic Publication: 2017 Jun 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Drug Delivery Systems*, Enzyme Inhibitors/*pharmacology , Farnesyltranstransferase/*metabolism , Protein Transport/*drug effects , ras Proteins/*metabolism, Cells, Cultured ; Enzyme Inhibitors/chemistry ; Models, Biological ; Protein Prenylation ; Signal Transduction/drug effects

المؤلفون: Fan Q; Department of Neurology, University of California, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94158, USA., Aksoy O; Department of Neurology, University of California, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94158, USA., Wong RA; Department of Neurology, University of California, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94158, USA., Ilkhanizadeh S; Department of Neurology, University of California, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94158, USA., Novotny CJ; Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA., Gustafson WC; Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94158, USA; Department of Pediatrics, University of California, San Francisco, CA 94158, USA., Truong AY; Department of Pediatrics, University of California, San Francisco, CA 94158, USA; Department of Neurological Surgery, University of California, San Francisco, CA 94158, USA., Cayanan G; Department of Neurology, University of California, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94158, USA., Simonds EF; Department of Neurology, University of California, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94158, USA., Haas-Kogan D; Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02215, USA., Phillips JJ; Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94158, USA; Department of Neurological Surgery, University of California, San Francisco, CA 94158, USA., Nicolaides T; Department of Pediatrics, University of California, San Francisco, CA 94158, USA; Department of Neurological Surgery, University of California, San Francisco, CA 94158, USA., Okaniwa M; Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA., Shokat KM; Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA., Weiss WA; Department of Neurology, University of California, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94158, USA; Department of Pediatrics, University of California, San Francisco, CA 94158, USA; Department of Neurological Surgery, University of California, San Francisco, CA 94158, USA. Electronic address: waweiss@gmail.com.

المصدر: Cancer cell [Cancer Cell] 2017 Mar 13; Vol. 31 (3), pp. 424-435.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: Brain Neoplasms/*drug therapy , Glioblastoma/*drug therapy , Multiprotein Complexes/*antagonists & inhibitors , Protein Kinase Inhibitors/*therapeutic use , TOR Serine-Threonine Kinases/*antagonists & inhibitors, Animals ; Cell Line, Tumor ; Female ; Humans ; Mechanistic Target of Rapamycin Complex 1 ; Mice ; Mice, Inbred BALB C ; Sirolimus/therapeutic use ; Tacrolimus Binding Protein 1A/physiology