المؤلفون: Jing Wang, M. Merve Susam, Changpei Gan, Rolf W. Sparidans, Maria C. Lebre, Jos H. Beijnen, Alfred H. Schinkel

المصدر: Pharmaceuticals, Vol 15, Iss 9, p 1124 (2022)

مصطلحات موضوعية: EAI045, ABCB1, ABCG2, brain accumulation, elacridar, Oatp1a/1b, Medicine, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1424-8247/15/9/1124; https://doaj.org/toc/1424-8247

URL الوصول: https://doaj.org/article/f35d28b40b0d4d2c8e00a50b67705a13

مصطلحات موضوعية: geneesmiddeltransporterende, muismodellen, ABCG2, OATP1A/1B, CYP3A, ABCB1, drug transporters, mouse models, ontgiftende enzymen, detoxification enzymes, farmacokinetiek, pharmacokinetics, Carboxylesterase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___00893::fbf71568e24e7148e67ab3de0fc19f1a
https://doi.org/10.33540/1317

المؤلفون: WANG, YAOGENG

المساهمون: Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Beijnen, Jos, Schinkel, A.H.

مصطلحات موضوعية: geneesmiddeltransporterende, muismodellen, ABCG2, OATP1A/1B, CYP3A, ABCB1, drug transporters, mouse models, ontgiftende enzymen, detoxification enzymes, farmacokinetiek, pharmacokinetics, Carboxylesterase

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______101::29580bef738ea097650f6fb10f05bf1b
https://dspace.library.uu.nl/handle/1874/420794

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المؤلفون: Li, Wenlong, Tibben, Matthijs, Wang, Yaogeng, Lebre, Maria C, Rosing, Hilde, Beijnen, Jos H, Schinkel, Alfred H, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology

المصدر: International Journal of Cancer, 146(6), 1631. Wiley-Liss Inc.

مصطلحات موضوعية: Genetically modified mouse, Cancer Research, ATP Binding Cassette Transporter, Subfamily B, Abcg2, CYP3A, Herb-Drug Interactions, Organic Anion Transporters, P-glycoprotein, Pharmacology, Madin Darby Canine Kidney Cells, Mice, 03 medical and health sciences, Dogs, 0302 clinical medicine, Pharmacokinetics, Transforming Growth Factor beta, Tetrahydroisoquinolines, ATP Binding Cassette Transporter, Subfamily G, Member 2, Animals, Cytochrome P-450 CYP3A, Humans, Galunisertib, Tissue Distribution, cytochrome P450-3A, Receptor, biology, CYP3A4, Chemistry, Brain, Oatp1a/1b, Neoplasm Proteins, brain accumulation, galunisertib, Oncology, oral availability, 030220 oncology & carcinogenesis, Quinolines, biology.protein, Acridines, Pyrazoles, Female, intestinal disposition, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce90e3ddebbd0e2bc1b7872e31bd5917
https://doi.org/10.1002/ijc.32568

المؤلفون: Li, Wenlong, Tibben, Matthijs, Wang, Yaogeng, Lebre, Maria C, Rosing, Hilde, Beijnen, Jos H, Schinkel, Alfred H

المساهمون: Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology

مصطلحات موضوعية: brain accumulation, galunisertib, oral availability, intestinal disposition, cytochrome P450-3A, P-glycoprotein, Oatp1a/1b

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______101::0ce757aa7128ed40489d273e65870d47
https://dspace.library.uu.nl/handle/1874/390157

المؤلفون: Wang, Jing, Bruin, Maaike A C, Gan, Changpei, Lebre, Maria C, Rosing, Hilde, Beijnen, Jos H, Schinkel, Alfred H, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology

المساهمون: Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology

المصدر: International Journal of Pharmaceutics, 581. Elsevier bedrijfsinformatie b.v.

مصطلحات موضوعية: Genetically modified mouse, Tivozanib, Abcg2, CYP3A, ABCG2, Administration, Oral, Pharmaceutical Science, Mice, Transgenic, 02 engineering and technology, Pharmacology, 030226 pharmacology & pharmacy, Madin Darby Canine Kidney Cells, Mice, 03 medical and health sciences, Dogs, 0302 clinical medicine, Pharmacokinetics, Oral administration, CYP3A enzymes, medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, Animals, Humans, Distribution (pharmacology), ATP Binding Cassette Transporter, Subfamily B, Member 1, Mice, Knockout, Brain penetration, biology, Chemistry, Phenylurea Compounds, Brain, ABCB1, Transporter, 021001 nanoscience & nanotechnology, Oatp1a/1b, Quinolines, biology.protein, Female, 0210 nano-technology, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754611a4da0d0591e2d9aa0336db7008
https://doi.org/10.1016/j.ijpharm.2020.119277

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