المؤلفون: Ciriello G; Swiss Cancer Center Leman, Lausanne, Switzerland.; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland., Magnani L; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, United Kingdom.; Breast Epigenetic Plasticity and Evolution Laboratory, Division of Breast Cancer Research, The Institute of Cancer Research, London, United Kingdom.; Department of Surgery and Cancer, Imperial College London, London, United Kingdom., Aitken SJ; Medical Research Council Toxicology Unit, University of Cambridge, Cambridge, United Kingdom.; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom., Akkari L; Division of Tumor Biology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Behjati S; Wellcome Sanger Institute, Hinxton, United Kingdom.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.; Department of Paediatrics, University of Cambridge, Cambridge, United Kingdom., Hanahan D; Swiss Cancer Center Leman, Lausanne, Switzerland.; Ludwig Institute for Cancer Research, Lausanne, Switzerland., Landau DA; New York Genome Center, New York, New York.; Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, New York.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, New York., Lopez-Bigas N; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Cáncer (CIBERONC), Instituto de Salud Carlos III, Madrid, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., Lupiáñez DG; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin Institute for Medical Systems Biology, Berlin, Germany., Marine JC; Laboratory for Molecular Cancer Biology, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory for Molecular Cancer Biology, Department of Oncology, KULeuven, Leuven, Belgium., Martin-Villalba A; Department of Molecular Neurobiology, German Cancer Research Center (DFKZ), Heidelberg, Germany., Natoli G; Department of Experimental Onco-logy, European Institute of Oncology IRCCS, Milan, Italy., Obenauf AC; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria., Oricchio E; Swiss Cancer Center Leman, Lausanne, Switzerland.; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland., Scaffidi P; Department of Experimental Onco-logy, European Institute of Oncology IRCCS, Milan, Italy.; Cancer Epigenetic Laboratory, The Francis Crick Institute, London, United Kingdom., Sottoriva A; Computational Biology Research Centre, Human Technopole, Milan, Italy., Swarbrick A; Cancer Ecosystems Program, Garvan Institute of Medical Research, Darlinghurst, Australia.; School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, Australia., Tonon G; Vita-Salute San Raffaele University, Milan, Italy.; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy., Vanharanta S; Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Biochemistry and Developmental Biology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Zuber J; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria.; Medical University of Vienna, Vienna BioCenter (VBC), Vienna, Austria.

المصدر: Cancer discovery [Cancer Discov] 2024 Jan 12; Vol. 14 (1), pp. 36-48.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/genetics , Neoplasms*/pathology, Humans ; Epigenomics ; Precision Medicine ; Tumor Microenvironment/genetics

المؤلفون: Bayerl F; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany., Meiser P; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany., Donakonda S; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany; German Center for Infection Research, Munich, Germany., Hirschberger A; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany., Lacher SB; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany., Pedde AM; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany., Hermann CD; Institute of Experimental Oncology, School of Medicine, Technical University of Munich, Munich, Germany., Elewaut A; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria., Knolle M; Institute for Artificial Intelligence in Medicine & Healthcare, School of Medicine, Technical University of Munich, Munich, Germany., Ramsauer L; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany., Rudolph TJ; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany., Grassmann S; Institute for Medical Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich, Munich, Germany., Öllinger R; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technical University of Munich, Munich, Germany., Kirchhammer N; Cancer Immunology, Department of Biomedicine, University and University Hospital Basel, Basel, Switzerland., Trefny M; Cancer Immunology, Department of Biomedicine, University and University Hospital Basel, Basel, Switzerland., Anton M; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany., Wohlleber D; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany., Höchst B; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany., Zaremba A; Department for Dermatology, University Hospital Essen, Essen, Germany., Krüger A; Institute of Experimental Oncology, School of Medicine, Technical University of Munich, Munich, Germany., Rad R; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technical University of Munich, Munich, Germany., Obenauf AC; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria., Schadendorf D; Department for Dermatology, University Hospital Essen, Essen, Germany., Zippelius A; Cancer Immunology, Department of Biomedicine, University and University Hospital Basel, Basel, Switzerland., Buchholz VR; Institute for Medical Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich, Munich, Germany., Schraml BU; Walter-Brendel Center for Experimental Medicine, LMU Munich, Planegg-Martinsried, Germany; Biomedical Center, Institute for Cardiovascular Physiology and Pathophysiology, LMU Munich, Planegg-Martinsried, Germany., Böttcher JP; Institute of Molecular Immunology, School of Medicine, Technical University of Munich, Munich, Germany. Electronic address: j.boettcher@tum.de.

المصدر: Immunity [Immunity] 2023 Jun 13; Vol. 56 (6), pp. 1341-1358.e11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE

مواضيع طبية MeSH: Dinoprostone* , Neoplasms*, Humans ; Antibodies ; CD8-Positive T-Lymphocytes ; Dendritic Cells ; Receptors, Prostaglandin E

المؤلفون: Leiendecker L; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University at Vienna and Medical University of Vienna, Vienna BioCenter (VBC), Vienna, Austria., Neumann T; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University at Vienna and Medical University of Vienna, Vienna BioCenter (VBC), Vienna, Austria.; Quantro Therapeutics, Vienna, Austria., Jung PS; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University at Vienna and Medical University of Vienna, Vienna BioCenter (VBC), Vienna, Austria.; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Cronin SM; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University at Vienna and Medical University of Vienna, Vienna BioCenter (VBC), Vienna, Austria., Steinacker TL; Institute of Molecular Biotechnology (IMBA), Vienna BioCenter (VBC), Vienna, Austria., Schleiffer A; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Schutzbier M; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Institute of Molecular Biotechnology (IMBA), Vienna BioCenter (VBC), Vienna, Austria.; The Gregor Mendel Institute of Molecular Plant Biology of the Austrian Academy of Sciences (GMI), Vienna BioCenter (VBC), Vienna, Austria., Mechtler K; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Institute of Molecular Biotechnology (IMBA), Vienna BioCenter (VBC), Vienna, Austria.; The Gregor Mendel Institute of Molecular Plant Biology of the Austrian Academy of Sciences (GMI), Vienna BioCenter (VBC), Vienna, Austria., Kervarrec T; Department of Pathology, University Hospital Center of Tours, University of Tours, Tours, France., Laurent E; PRISM INSERM U1192, Université de Lille, Villeneuve d'Ascq, France., Bachiri K; PRISM INSERM U1192, Université de Lille, Villeneuve d'Ascq, France., Coyaud E; PRISM INSERM U1192, Université de Lille, Villeneuve d'Ascq, France., Murali R; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York., Busam KJ; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York., Itzinger-Monshi B; Department of Dermatology, Hospital Rudolfstiftung, Vienna, Austria., Kirnbauer R; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Cerroni L; Department of Dermatology, Medical University of Graz, Graz, Austria., Calonje E; Department of Dermatopathology, St John's Institute of Dermatology, St Thomas' Hospital, London, United Kingdom., Rütten A; Dermatopathology Friedrichshafen, Friedrichshafen, Germany., Stubenrauch F; University Hospital Tuebingen, Institute for Medical Virology and Epidemiology of Viral Diseases, Tuebingen, Germany., Griewank KG; Department of Dermatology, University Hospital Essen, University of Duisburg, German Cancer Consortium (DKTK), Partner Site, Essen, Germany., Wiesner T; Department of Dermatology, Medical University of Vienna, Vienna, Austria.; Department of Pathology, Medical University of Vienna, Vienna, Austria., Obenauf AC; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.

المصدر: Cancer discovery [Cancer Discov] 2023 Jan 09; Vol. 13 (1), pp. 70-84.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Papillomavirus Infections*/complications , Uterine Cervical Neoplasms* , Skin Neoplasms* , Bone Neoplasms* , Breast Neoplasms* , Adenocarcinoma, Clear Cell* , Adenocarcinoma, Papillary*, Female ; Humans ; Human Papillomavirus Viruses ; Papillomaviridae/genetics ; Germ Cells/pathology

المؤلفون: Obenauf AC; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria. Email: anna.obenauf@imp.ac.at.

المصدر: Science translational medicine [Sci Transl Med] 2022 Jul 27; Vol. 14 (655), pp. eadd0887. Date of Electronic Publication: 2022 Jul 27.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/therapy, Combined Modality Therapy ; Humans

المؤلفون: Leiendecker L; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Campus-Vienna-BioCenter 1, Vienna, 1030, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, Vienna, 1030, Austria., Jung PS; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Campus-Vienna-BioCenter 1, Vienna, 1030, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, Vienna, 1030, Austria.; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Obenauf AC; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Campus-Vienna-BioCenter 1, Vienna, 1030, Austria.

المصدر: The British journal of dermatology [Br J Dermatol] 2022 Feb; Vol. 186 (2), pp. 209-210. Date of Electronic Publication: 2021 Nov 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Comment

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0004041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2133 (Electronic) Linking ISSN: 00070963 NLM ISO Abbreviation: Br J Dermatol Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Merkel Cell*/drug therapy , Carcinoma, Merkel Cell*/pathology , Immunoconjugates*/therapeutic use , Skin Neoplasms*/drug therapy , Skin Neoplasms*/pathology, Biomarkers, Tumor ; Humans

المؤلفون: Breitenecker K; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, AT-1090 Vienna, Austria.; Institute of Cancer Research, Medical University of Vienna, AT-1090 Vienna, Austria.; Comprehensive Cancer Center (CCC), Medical University of Vienna, AT-1090 Vienna, Austria., Homolya M; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, AT-1090 Vienna, Austria., Luca AC; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, AT-1090 Vienna, Austria., Lang V; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, AT-1090 Vienna, Austria., Trenk C; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, AT-1090 Vienna, Austria., Petroczi G; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, AT-1090 Vienna, Austria., Mohrherr J; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, AT-1090 Vienna, Austria., Horvath J; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, AT-1090 Vienna, Austria., Moritsch S; Institute of Cancer Research, Medical University of Vienna, AT-1090 Vienna, Austria.; Comprehensive Cancer Center (CCC), Medical University of Vienna, AT-1090 Vienna, Austria., Haas L; Research Institute of Molecular Pathology, Vienna Biocenter, AT-1030 Vienna, Austria., Kurnaeva M; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, AT-1090 Vienna, Austria., Eferl R; Institute of Cancer Research, Medical University of Vienna, AT-1090 Vienna, Austria.; Comprehensive Cancer Center (CCC), Medical University of Vienna, AT-1090 Vienna, Austria., Stoiber D; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, AT-1090 Vienna, Austria.; Division Pharmacology, Department of Pharmacology, Physiology and Microbiology, Karl Landsteiner University of Health Sciences, AT-3500 Krems, Austria., Moriggl R; Institute of Animal Breeding and Genetics, University of Veterinary Medicine, AT-1210 Vienna, Austria., Bilban M; Department of Laboratory Medicine, Medical University of Vienna, AT-1090 Vienna, Austria.; Core Facilities, Medical University of Vienna, AT-1090 Vienna, Austria., Obenauf AC; Research Institute of Molecular Pathology, Vienna Biocenter, AT-1030 Vienna, Austria., Ferran C; Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.; Transplant Institute and the Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Dome B; Division of Thoracic Surgery, Department of Surgery, and Comprehensive Cancer Center (CCC), Medical University of Vienna, AT-1090 Vienna, Austria.; 1st Department of Tumor Biology, National Korányi Institute of Pulmonology, Semmelweis University, HU-1121 Budapest, Hungary.; Department of Thoracic Surgery, National Institute of Oncology and Semmelweis University, HU-1122 Budapest, Hungary., Laszlo V; Division of Thoracic Surgery, Department of Surgery, and Comprehensive Cancer Center (CCC), Medical University of Vienna, AT-1090 Vienna, Austria.; 1st Department of Tumor Biology, National Korányi Institute of Pulmonology, Semmelweis University, HU-1121 Budapest, Hungary., Győrffy B; MTA TTK Lendület Cancer Biomarker Research Group, Institute of Enzymology, and 2nd Department of Pediatrics, Semmelweis University, HU-1117 Budapest, Hungary.; Department of Bioinformatics, Semmelweis University, HU-1094 Budapest, Hungary.; 2nd Department of Pediatrics, Semmelweis University, HU-1094 Budapest, Hungary., Dezso K; 1st Department of Pathology and Experimental Cancer Research, Semmelweis University, HU-1085 Budapest, Hungary., Moldvay J; 1st Department of Pulmonology, National Korányi Institute of Pulmonology, HU-1121 Budapest, Hungary.; SE-NAP Brain Metastasis Research Group, 2nd Department of Pathology, Semmelweis University, HU-1122 Budapest, Hungary., Casanova E; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, AT-1090 Vienna, Austria.; Comprehensive Cancer Center (CCC), Medical University of Vienna, AT-1090 Vienna, Austria., Moll HP; Institute of Pharmacology, Center of Physiology and Pharmacology, Medical University of Vienna, AT-1090 Vienna, Austria. herwig.moll@meduniwien.ac.at.; Comprehensive Cancer Center (CCC), Medical University of Vienna, AT-1090 Vienna, Austria.

المصدر: Science translational medicine [Sci Transl Med] 2021 Jul 07; Vol. 13 (601).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Adenocarcinoma of Lung*/genetics , Lung Neoplasms*/genetics, Tumor Necrosis Factor alpha-Induced Protein 3/*genetics, Animals ; B7-H1 Antigen/genetics ; B7-H1 Antigen/metabolism ; Down-Regulation ; Humans ; Interferon-gamma/metabolism ; Mice ; Signal Transduction

المؤلفون: Haas L; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria., Elewaut A; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria., Gerard CL; Department of Oncology, Lausanne University Hospital, Lausanne, Switzerland., Umkehrer C; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria., Leiendecker L; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria., Pedersen M; Institute of Cancer Research, London, UK., Krecioch I; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria., Hoffmann D; Institute of Molecular Biotechnology, Vienna Biocenter, Vienna, Austria., Novatchkova M; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria., Kuttke M; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria.; Institute of Vascular Biology and Thrombosis Research, Medical University of Vienna, Vienna, Austria., Neumann T; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria., da Silva IP; Melanoma Institute Australia, University of Sydney, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia., Witthock H; Institute of Cancer Research, London, UK., Cuendet MA; Department of Oncology, Lausanne University Hospital, Lausanne, Switzerland.; Molecular Modeling Group, Swiss Institute of Bioinformatics, UNIL Sorge, Lausanne, Switzerland.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA., Carotta S; Boehringer Ingelheim RCV GmBH & Co KG, Vienna, Austria., Harrington KJ; Institute of Cancer Research, London, UK., Zuber J; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria., Scolyer RA; Melanoma Institute Australia, University of Sydney, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.; Royal Prince Alfred Hospital & NSW Health Pathology, Sydney, New South Wales, Australia., Long GV; Melanoma Institute Australia, University of Sydney, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.; Royal North Shore Hospital, Sydney, New South Wales, Australia.; Mater Hospital, North Sydney, New South Wales, Australia., Wilmott JS; Melanoma Institute Australia, University of Sydney, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.; Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia., Michielin O; Department of Oncology, Lausanne University Hospital, Lausanne, Switzerland.; Molecular Modeling Group, Swiss Institute of Bioinformatics, UNIL Sorge, Lausanne, Switzerland., Vanharanta S; MRC Cancer Unit, University of Cambridge, Cambridge, UK., Wiesner T; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Obenauf AC; Research Institute of Molecular Pathology, Vienna Biocenter, Vienna, Austria. anna.obenauf@imp.ac.at.

المصدر: Nature cancer [Nat Cancer] 2021 Jul; Vol. 2 (7), pp. 693-708. Date of Electronic Publication: 2021 Jul 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Melanoma*/drug therapy , Tumor Microenvironment*, Animals ; Humans ; Immune Evasion ; Immunologic Factors/therapeutic use ; Immunotherapy ; Mice ; Neoplasm Recurrence, Local ; Protein Kinase Inhibitors/pharmacology

المؤلفون: Umkehrer C; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Holstein F; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Formenti L; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Jude J; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Froussios K; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Neumann T; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Cronin SM; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Haas L; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Lipp JJ; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Boehringer Ingelheim RCV GmbH & Co. KG, Vienna, Austria., Burkard TR; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Fellner M; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Wiesner T; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Zuber J; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Medical University of Vienna, Vienna BioCenter (VBC), Vienna, Austria., Obenauf AC; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria. anna.obenauf@imp.ac.at.

المصدر: Nature biotechnology [Nat Biotechnol] 2021 Feb; Vol. 39 (2), pp. 174-178. Date of Electronic Publication: 2020 Jul 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Cell Separation* , Genes, Reporter*, CRISPR-Cas Systems/*genetics , Clone Cells/*metabolism, Animals ; Cell Line ; Female ; Humans ; Melanoma/pathology ; Mice, Inbred C57BL ; Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors ; Protein Kinase Inhibitors/pharmacology ; raf Kinases/antagonists & inhibitors ; Mice

المؤلفون: Leiendecker L; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Jung PS; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Krecioch I; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Neumann T; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Schleiffer A; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Mechtler K; Institute of Molecular Biotechnology (IMBA), Vienna BioCenter (VBC), Vienna, Austria., Wiesner T; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Obenauf AC; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.

المصدر: EMBO molecular medicine [EMBO Mol Med] 2020 Nov 06; Vol. 12 (11), pp. e12525. Date of Electronic Publication: 2020 Oct 07.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: EMBO Press Country of Publication: England NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Merkel Cell*/drug therapy , Carcinoma, Merkel Cell*/genetics , Skin Neoplasms*/drug therapy, Cell Death ; Cell Differentiation ; Histone Demethylases/genetics ; Humans

المؤلفون: Haas L; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria., Obenauf AC; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria.

المصدر: Frontiers in immunology [Front Immunol] 2019 Nov 28; Vol. 10, pp. 2746. Date of Electronic Publication: 2019 Nov 28 (Print Publication: 2019).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Tumor Microenvironment*/genetics , Tumor Microenvironment*/immunology, Myeloid Cells/*immunology , Myeloid Cells/*metabolism , Neoplasms/*etiology , Neoplasms/*metabolism, Animals ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Humans ; Immunity ; Immunotherapy ; Lymphocytes, Tumor-Infiltrating/immunology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Lymphocytes, Tumor-Infiltrating/pathology ; Macrophages/immunology ; Macrophages/metabolism ; Myeloid Cells/pathology ; Neoplasms/pathology ; Neoplasms/therapy ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; T-Lymphocytes/pathology ; Tumor Escape