المؤلفون: Céline Prévost, Eric Brohan, Odile Angouillant-Boniface, G.Andrees Böhme, Sylvie Houtmann, Céline Chantoiseau, Thierry Carriot, Veronique Ballet, Sophie Fouconnier, Laurent Schio, Michel Partiseti, Rachid Boukaiba, Jean-Marie Chambard, Brigitte Schombert

المصدر: European Journal of Pharmacology. 915:174670

مصطلحات موضوعية: Patch-Clamp Techniques, Purkinje fibers, hERG, Action Potentials, Pharmacology, Ion Channels, Membrane Potentials, Afterdepolarization, Purkinje Fibers, Antimalarials, Electrocardiography, medicine, Animals, Humans, Ion channel, biology, Chemistry, Arrhythmias, Cardiac, Heart, Stereoisomerism, Cardiac action potential, Resting potential, Ether-A-Go-Go Potassium Channels, Potassium channel, Electrophysiology, medicine.anatomical_structure, biology.protein, Rabbits, Electrophysiologic Techniques, Cardiac, Hydroxychloroquine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2889049ef9d687d5261e5fde9ce6f50
https://doi.org/10.1016/j.ejphar.2021.174670

المؤلفون: Jean Christophe Carry, Youssef El-Ahmad, Bruno Filoche-Romme, Frank Halley, Loic Vincent, Andreas Karlsson, Thomas Bertrand, Christoph Lengauer, Tsiala Benard, Pierre Yves Abecassis, Peter Below, Alexey Rak, Jean Paul Nicolas, Gilles Lebourg, Audrey Louboutin, Victor Certal, Laurent Schio, Cécile Delorme, Nadine Michot, Fabienne Pilorge, Fabienne Chatreaux, Pascale Lejeune, Fabienne Thompson, Angela Virone-Oddos, Isabelle Vade, Hélène Bonnevaux, Jean Pierre Marquette, Odile Angouillant-Boniface

المصدر: Journal of Medicinal Chemistry. 55:4788-4805

مصطلحات موضوعية: Models, Molecular, Gene isoform, Benzimidazole, Class I Phosphatidylinositol 3-Kinases, Antineoplastic Agents, Mice, SCID, Pyrimidinones, Pharmacology, Crystallography, X-Ray, medicine.disease_cause, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, PTEN, Tensin, Pyrimidone, Phosphorylation, PI3K/AKT/mTOR pathway, Benzoxazoles, Molecular Structure, biology, Kinase, Chemistry, Macrophages, PTEN Phosphohydrolase, Neoplasms, Experimental, Fibroblasts, Xenograft Model Antitumor Assays, Isoenzymes, biology.protein, Molecular Medicine, Benzimidazoles, Carcinogenesis, Proto-Oncogene Proteins c-akt, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da44cb5e3b90d40fe34a0bb8a89c84d
https://doi.org/10.1021/jm300241b

المؤلفون: Kirsten Bjergarde, Cécile Delorme, Pierre-Yves Abecassis, Alain Krick, Jean-Paul Nicolas, Gilles Doerflinger, Sébastien Perron, Michel Murer, Houlfa Guizani, Bruno Filoche-Romme, Sylvette Lachaud, Ronan Le Moigne, Céline Prévost, Cécile Combeau, Jacques Mauger, Jean-Christophe Carry, Stéphanie Pouzieux, Laure Delarbre, Laurent Schio, Francois Clerc, Marie-Line Monteiro, Hervé Minoux, Sylvie Monget, Thomas Bertrand, Véronique Crocq-Stuerga, Ma Nina, Francis Gasse, Odile Angouillant-Boniface, Rémi Lebel, Sébastien Maignan, Sylvie Gontier, Anil Nair, Eric Parmantier

المصدر: Journal of medicinal chemistry. 58(1)

مصطلحات موضوعية: Models, Molecular, Aurora inhibitor, Antineoplastic Agents, Mice, SCID, Quinolones, Serine, Small Molecule Libraries, Aurora Kinases, Neoplasms, Drug Discovery, Sf9 Cells, Animals, Aurora Kinase B, Humans, Aurora Kinase C, Mitosis, Protein Kinase Inhibitors, Aurora Kinase A, Molecular Structure, Kinase, Chemistry, HCT116 Cells, Small molecule, Xenograft Model Antitumor Assays, Cell biology, Protein Structure, Tertiary, Models, Chemical, Molecular Medicine, Benzimidazoles, Female, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3efa98d742ac08ebfaa138362d1053b5
https://pubmed.ncbi.nlm.nih.gov/25369539