المؤلفون: Metibemu DS; Chemistry and Biotechnology Science and Engineering Programs, The University of Alabama in Huntsville, 301 Sparkman Drive, Huntsville, Alabama 35899, United States., Adeyinka OS; Chemistry and Biotechnology Science and Engineering Programs, The University of Alabama in Huntsville, 301 Sparkman Drive, Huntsville, Alabama 35899, United States., Falode J; Chemistry and Biotechnology Science and Engineering Programs, The University of Alabama in Huntsville, 301 Sparkman Drive, Huntsville, Alabama 35899, United States., Crown O; Chemistry and Biotechnology Science and Engineering Programs, The University of Alabama in Huntsville, 301 Sparkman Drive, Huntsville, Alabama 35899, United States., Ogungbe IV; Chemistry and Biotechnology Science and Engineering Programs, The University of Alabama in Huntsville, 301 Sparkman Drive, Huntsville, Alabama 35899, United States.

المصدر: ACS infectious diseases [ACS Infect Dis] 2024 Aug 09; Vol. 10 (8), pp. 2507-2524. Date of Electronic Publication: 2024 Jul 11.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Alphavirus*/drug effects , Alphavirus*/chemistry , Antiviral Agents*/pharmacology , Antiviral Agents*/chemistry , Viral Nonstructural Proteins*/antagonists & inhibitors , Viral Nonstructural Proteins*/chemistry, Humans ; Alphavirus Infections/drug therapy ; Alphavirus Infections/virology ; Animals ; Viral Structural Proteins/chemistry ; Viral Structural Proteins/antagonists & inhibitors

المؤلفون: Metibemu DS; Chemistry and Biotechnology Science and Engineering Program, College of Science, The University of Alabama in Huntsville, Huntsville, AL, 35899, USA., Adeyinka OS; Chemistry and Biotechnology Science and Engineering Program, College of Science, The University of Alabama in Huntsville, Huntsville, AL, 35899, USA., Falode J; Chemistry and Biotechnology Science and Engineering Program, College of Science, The University of Alabama in Huntsville, Huntsville, AL, 35899, USA., Hampton T; Chemistry and Biotechnology Science and Engineering Program, College of Science, The University of Alabama in Huntsville, Huntsville, AL, 35899, USA., Crown O; Chemistry and Biotechnology Science and Engineering Program, College of Science, The University of Alabama in Huntsville, Huntsville, AL, 35899, USA., Ojobor JC; Chemistry and Biotechnology Science and Engineering Program, College of Science, The University of Alabama in Huntsville, Huntsville, AL, 35899, USA., Narayanan A; Department of Biology, College of Science, George Mason University, Fairfax, VA, 22030, USA., Julander J; Institute for Antiviral Research and the Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT, 84322, USA., Ogungbe IV; Chemistry and Biotechnology Science and Engineering Program, College of Science, The University of Alabama in Huntsville, Huntsville, AL, 35899, USA. Electronic address: victor.ogungbe@uah.edu.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2024 Nov 15; Vol. 278, pp. 116808. Date of Electronic Publication: 2024 Aug 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Chikungunya virus*/drug effects , Chikungunya Fever*/drug therapy , Antiviral Agents*/pharmacology , Antiviral Agents*/chemistry , Antiviral Agents*/chemical synthesis , Disease Models, Animal*, Animals ; Mice ; Humans ; Protease Inhibitors/pharmacology ; Protease Inhibitors/chemistry ; Protease Inhibitors/chemical synthesis ; Structure-Activity Relationship ; Dose-Response Relationship, Drug ; Molecular Structure ; Cysteine Endopeptidases/metabolism ; Microsomes, Liver/metabolism ; Virus Replication/drug effects

المؤلفون: Ajayi O; Department of Chemistry, Physics, and Atmospheric Sciences, Jackson State University, Jackson, MS, 39217, USA., Metibemu DS; Department of Chemistry, Physics, and Atmospheric Sciences, Jackson State University, Jackson, MS, 39217, USA; Department of Chemistry, The University of Alabama in Huntsville, Huntsville, AL, 35899, USA., Crown O; Department of Chemistry, Physics, and Atmospheric Sciences, Jackson State University, Jackson, MS, 39217, USA; Department of Chemistry, The University of Alabama in Huntsville, Huntsville, AL, 35899, USA., Adeyinka OS; Department of Chemistry, Physics, and Atmospheric Sciences, Jackson State University, Jackson, MS, 39217, USA; Department of Chemistry, The University of Alabama in Huntsville, Huntsville, AL, 35899, USA., Kaiser M; Swiss Tropical and Public Health Institute, Kreuzstrasse 2, 4123, Allschwil, Switzerland; University of Basel, 4001, Basel, Switzerland., Shoji N; Department of Microbiology, New York University Grossman School of Medicine, New York, NY, 10010, USA., Silva M; University of Basel, 4001, Basel, Switzerland., Rodriguez A; Department of Microbiology, New York University Grossman School of Medicine, New York, NY, 10010, USA., Ogungbe IV; Department of Chemistry, Physics, and Atmospheric Sciences, Jackson State University, Jackson, MS, 39217, USA; Department of Chemistry, The University of Alabama in Huntsville, Huntsville, AL, 35899, USA. Electronic address: victor.ogungbe@uah.edu.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2024 Jan 05; Vol. 263, pp. 115954. Date of Electronic Publication: 2023 Nov 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Trypanocidal Agents*/pharmacology , Trypanocidal Agents*/therapeutic use , Trypanosomiasis, African*/drug therapy , Trypanosomiasis, African*/parasitology , Trypanosoma brucei brucei*, Animals ; Mice ; Humans ; Trypanosoma brucei rhodesiense ; Trypanosoma brucei gambiense

المؤلفون: Kim PY; Department of Biological Sciences, Grambling State University, Grambling, LA, United States of America., Kim AY; Department of Biological Sciences, Grambling State University, Grambling, LA, United States of America., Newman JJ; School of Biological Sciences, Louisiana Tech University, Ruston, LA, United States of America., Cella E; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, United States of America., Bishop TC; Physics and Chemistry Programs, Louisiana Tech University, Ruston, LA, United States of America., Huwe PJ; Mercer University School of Medicine, Macon, GA, United States of America., Uchakina ON; Mercer University School of Medicine, Macon, GA, United States of America., McKallip RJ; Mercer University School of Medicine, Macon, GA, United States of America., Mack VL; Mercer Medicine, Macon, GA, United States of America., Hill MP; Mercer Medicine, Macon, GA, United States of America., Ogungbe IV; Department of Chemistry, Jackson State University, Jackson, MS, United States of America., Adeyinka O; Department of Chemistry, Jackson State University, Jackson, MS, United States of America., Jones S; Health Services Center, Jackson State University, Jackson, MS, United States of America., Ware G; Center of Excellence for Emerging Viral Threats, Louisiana State University Health Shreveport, Shreveport, LA, United States of America., Carroll J; Center of Excellence for Emerging Viral Threats, Louisiana State University Health Shreveport, Shreveport, LA, United States of America., Sawyer JF; Center of Excellence for Emerging Viral Threats, Louisiana State University Health Shreveport, Shreveport, LA, United States of America., Densmore KH; Center of Excellence for Emerging Viral Threats, Louisiana State University Health Shreveport, Shreveport, LA, United States of America., Foster M; School of Biological Sciences, Louisiana Tech University, Ruston, LA, United States of America., Valmond L; Department of Biological Sciences, Grambling State University, Grambling, LA, United States of America., Thomas J; Department of Biological Sciences, Grambling State University, Grambling, LA, United States of America., Azarian T; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, United States of America., Queen K; Center of Excellence for Emerging Viral Threats, Louisiana State University Health Shreveport, Shreveport, LA, United States of America., Kamil JP; Center of Excellence for Emerging Viral Threats, Louisiana State University Health Shreveport, Shreveport, LA, United States of America.; Department of Microbiology and Immunology, Louisiana State University Health Shreveport, Shreveport, LA, United States of America.

المصدر: PLOS global public health [PLOS Glob Public Health] 2023 Jul 19; Vol. 3 (7), pp. e0001935. Date of Electronic Publication: 2023 Jul 19 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 9918283779606676 Publication Model: eCollection Cited Medium: Internet ISSN: 2767-3375 (Electronic) Linking ISSN: 27673375 NLM ISO Abbreviation: PLOS Glob Public Health Subsets: PubMed not MEDLINE

المؤلفون: Coy-Barrera E; Bioorganic Chemistry Laboratory, Military University Nueva Granada, Nueva Granada Campus, Cajicá 250247, Colombia., Ogungbe IV; Department of Chemistry, Jackson State University, Jackson, MS 39217-0095, USA., Schmidt TJ; Institute of Pharmaceutical Biology and Phytochemistry (IPBP), University of Münster, PharmaCampus-Corrensstrasse 48, D-48149 Münster, Germany.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2023 Apr 25; Vol. 28 (9). Date of Electronic Publication: 2023 Apr 25.

نوع المنشور: Editorial

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Biological Products*/pharmacology , Biological Products*/therapeutic use, Animals ; Drug Discovery ; Fungi ; Plants

المؤلفون: Adeyinka OS; Department of Chemistry, Physics and Atmospheric Sciences Jackson State University, Jackson, MS, 39217, USA. adeyinka.olawale@gmail.com., Tabassum B; School of Biological Sciences, University of the Punjab, Lahore, Pakistan., Koloko BL; University Institute of Technology, University of Douala, Douala, Cameroon., Ogungbe IV; Department of Chemistry, Physics and Atmospheric Sciences Jackson State University, Jackson, MS, 39217, USA.

المصدر: Planta [Planta] 2023 Mar 13; Vol. 257 (4), pp. 78. Date of Electronic Publication: 2023 Mar 13.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Springer-Verlag [etc.] Country of Publication: Germany NLM ID: 1250576 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-2048 (Electronic) Linking ISSN: 00320935 NLM ISO Abbreviation: Planta Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems*/genetics , Crops, Agricultural*/genetics , Plant Breeding*, Gene Editing ; Genome, Plant/genetics ; Mutagenesis, Site-Directed ; Plants, Genetically Modified/genetics

المؤلفون: Boghdeh NA; Biomedical Research Laboratory, George Mason University, Manassas, VA 20110, USA., McGraw B; School of Systems Biology, College of Science, George Mason University, Manassas, VA 20110, USA., Barrera MD; Biomedical Research Laboratory, George Mason University, Manassas, VA 20110, USA.; School of Systems Biology, College of Science, George Mason University, Manassas, VA 20110, USA., Anderson C; Biomedical Research Laboratory, George Mason University, Manassas, VA 20110, USA.; School of Systems Biology, College of Science, George Mason University, Manassas, VA 20110, USA., Baha H; Biomedical Research Laboratory, George Mason University, Manassas, VA 20110, USA.; School of Systems Biology, College of Science, George Mason University, Manassas, VA 20110, USA., Risner KH; Biomedical Research Laboratory, George Mason University, Manassas, VA 20110, USA.; School of Systems Biology, College of Science, George Mason University, Manassas, VA 20110, USA., Ogungbe IV; Department of Chemistry, Physics and Atmospheric Sciences, Jackson State University, Jackson, MS 39217, USA., Alem F; Biomedical Research Laboratory, George Mason University, Manassas, VA 20110, USA.; School of Systems Biology, College of Science, George Mason University, Manassas, VA 20110, USA., Narayanan A; Biomedical Research Laboratory, George Mason University, Manassas, VA 20110, USA.; Department of Biology, College of Science, George Mason University, Fairfax, VA 22030, USA.

المصدر: Viruses [Viruses] 2023 Feb 28; Vol. 15 (3). Date of Electronic Publication: 2023 Feb 28.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: Alphavirus* , Encephalitis Virus, Venezuelan Equine*, Humans ; Horses ; Animals ; Antiviral Agents/pharmacology ; Ubiquitin ; Signal Transduction

المؤلفون: Kim PY; Department of Biological Sciences, Grambling State University, Grambling, LA., Kim AY; Department of Biological Sciences, Grambling State University, Grambling, LA., Newman JJ; School of Biological Sciences, Louisiana Tech University, Ruston, LA., Cella E; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL., Bishop TC; Physics and Chemistry Programs, Louisiana Tech University, Ruston, LA., Huwe PJ; Mercer University School of Medicine, Macon, GA., Uchakina ON; Mercer University School of Medicine, Macon, GA., McKallip RJ; Mercer University School of Medicine, Macon, GA., Mack VL; Mercer Medicine, Macon, GA., Hill MP; Mercer Medicine, Macon, GA., Ogungbe IV; Department of Chemistry, Jackson State University, Jackson, MS., Adeyinka O; Department of Chemistry, Jackson State University, Jackson, MS., Jones S; Health Services Center, Jackson State University, Jackson, MS., Ware G; Center of Excellence for Emerging Viral Threats, Louisiana State University Health Shreveport, Shreveport, LA., Carroll J; Center of Excellence for Emerging Viral Threats, Louisiana State University Health Shreveport, Shreveport, LA., Sawyer JF; Center of Excellence for Emerging Viral Threats, Louisiana State University Health Shreveport, Shreveport, LA., Densmore KH; Center of Excellence for Emerging Viral Threats, Louisiana State University Health Shreveport, Shreveport, LA., Foster M; School of Biological Sciences, Louisiana Tech University, Ruston, LA., Valmond L; Department of Biological Sciences, Grambling State University, Grambling, LA., Thomas J; Department of Biological Sciences, Grambling State University, Grambling, LA., Azarian T; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL., Queen K; Center of Excellence for Emerging Viral Threats, Louisiana State University Health Shreveport, Shreveport, LA., Kamil JP; Center of Excellence for Emerging Viral Threats, Louisiana State University Health Shreveport, Shreveport, LA.; Department of Microbiology and Immunology, Louisiana State University Health Shreveport, Shreveport, LA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2022 Oct 20. Date of Electronic Publication: 2022 Oct 20.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Metibemu DS; Department of Chemistry, Physics, and Atmospheric Sciences, Jackson State University, Jackson, MS 39217-0095, USA., Ogungbe IV; Department of Chemistry, Physics, and Atmospheric Sciences, Jackson State University, Jackson, MS 39217-0095, USA.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2022 Sep 15; Vol. 27 (18). Date of Electronic Publication: 2022 Sep 15.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Biological Products*/pharmacology , Carotenoids*/metabolism, Animals ; Cholesterol ; Diphosphates/metabolism ; Drug Discovery ; Humans ; Kelch-Like ECH-Associated Protein 1/metabolism ; NF-E2-Related Factor 2/metabolism ; NF-kappa B/metabolism ; Plants/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Solvents ; TOR Serine-Threonine Kinases/metabolism ; Terpenes/metabolism

المؤلفون: Nyamwihura RJ; Department of Chemistry, Jackson State University 1400 John R. Lynch Street Jackson MS 39217 USA Ifedayo.v.ogungbe@jsums.edu +1-601-979-3719., Ogungbe IV; Department of Chemistry, Jackson State University 1400 John R. Lynch Street Jackson MS 39217 USA Ifedayo.v.ogungbe@jsums.edu +1-601-979-3719.

المصدر: RSC advances [RSC Adv] 2022 Apr 12; Vol. 12 (18), pp. 11346-11375. Date of Electronic Publication: 2022 Apr 12 (Print Publication: 2022).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101581657 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-2069 (Electronic) Linking ISSN: 20462069 NLM ISO Abbreviation: RSC Adv Subsets: PubMed not MEDLINE