نتائج البحث - "Olaf Brouwers"

المساهمون: Interne Geneeskunde, Ondersteunend personeel CD, Promovendi CD, RS: CARIM - R3.08 - Regenerative and reconstructive medicine for vascular disease, Fysiologie, RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, Beeldvorming, MUMC+: DA BV Klinisch Fysicus (9), MUMC+: HVC Pieken Maastricht Studie (9), RS: CARIM - R3.01 - Vascular complications of diabetes and the metabolic syndrome, MUMC+: MA Interne Geneeskunde (3)

المصدر: Glycoconjugate Journal, 33(4), 627-630. Springer
Glycoconjugate Journal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a8f49cd82329dd67bfc601afb71de3
https://doi.org/10.1007/s10719-016-9681-3

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4

Delayed Intervention With Pyridoxamine Improves Metabolic Function and Prevents Adipose Tissue Inflammation and Insulin Resistance in High-Fat Diet–Induced Obese Mice

المؤلفون: Ben J. A. Janssen, Coen D.A. Stehouwer, Olaf Brouwers, Katrien H.J. Gaens, Kristiaan Wouters, Casper G. Schalkwijk, Toshio Miyata, Jack P.M. Cleutjens, Dionne E. Maessen

المساهمون: Promovendi CD, Interne Geneeskunde, RS: CARIM - R3.01 - Vascular complications of diabetes and the metabolic syndrome, Pathologie, RS: CARIM - R3.06 - The vulnerable plaque: makers and markers, Farmacologie en Toxicologie, RS: CARIM - R2.03 - ECM + Wnt signaling, MUMC+: MA Interne Geneeskunde (3)

المصدر: Diabetes, 65(4), 956-966. American Diabetes Association

مصطلحات موضوعية: Heart Defects, Congenital, Male, 0301 basic medicine, medicine.medical_specialty, Panniculitis, Endocrinology, Diabetes and Metabolism, Mice, Obese, Adipose tissue, 030209 endocrinology & metabolism, Inflammation, Type 2 diabetes, Biology, Carbohydrate metabolism, Diet, High-Fat, Drug Administration Schedule, Gigantism, Time-to-Treatment, Proinflammatory cytokine, Mice, 03 medical and health sciences, 0302 clinical medicine, Insulin resistance, 3T3-L1 Cells, Intellectual Disability, Internal medicine, Internal Medicine, medicine, Animals, Humans, Obesity, Cells, Cultured, Arrhythmias, Cardiac, Genetic Diseases, X-Linked, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Adipose Tissue, Adipogenesis, Insulin Resistance, Adipocyte hypertrophy, medicine.symptom, Pyridoxamine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea215cb1573086c7a12daf254d0f18a
https://doi.org/10.2337/db15-1390

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Glyoxalase 1 overexpression does not affect atherosclerotic lesion size and severity in ApoE(-/-) mice with or without diabetes

المؤلفون: Jack P.M. Cleutjens, Erwin Wijnands, Marion J.J. Gijbels, Jo G. R. De Mey, Erik A.L. Biessen, Kristiaan Wouters, Toshio Miyata, Olaf Brouwers, Coen D.A. Stehouwer, Casper G. Schalkwijk, Nordin M J Hanssen

المساهمون: MUMC+: MA Med Staf Artsass Interne Geneeskunde (9), Interne Geneeskunde, Pathologie, Moleculaire Genetica, MUMC+: MA Interne Geneeskunde (3), RS: CARIM - R3 - Vascular biology, Genetica & Celbiologie, Farmacologie en Toxicologie, Medical Biochemistry

المصدر: Cardiovascular Research, 104(1), 160-170. Oxford University Press
Cardiovascular research, 104(1), 160-170. Oxford University Press
Hanssen, N M J, Brouwers, O, Gijbels, M J, Wouters, K, Wijnands, E, Cleutjens, J P M, De Mey, J G, Miyata, T, Biessen, E A, Stehouwer, C D A & Schalkwijk, C G 2014, ' Glyoxalase 1 overexpression does not affect atherosclerotic lesion size and severity in ApoE-/-mice with or without diabetes ', Cardiovascular Research, vol. 104, no. 1, pp. 160-170 . https://doi.org/10.1093/cvr/cvu189

مصطلحات موضوعية: Apolipoprotein E, Glycation End Products, Advanced, medicine.medical_specialty, Physiology, Aortic Diseases, Inflammation, Aorta, Thoracic, Mice, Transgenic, Systemic inflammation, Severity of Illness Index, Streptozocin, Diabetes Mellitus, Experimental, Lesion, Lactoylglutathione lyase, Apolipoproteins E, Glycation, Physiology (medical), Internal medicine, medicine.artery, medicine, Animals, Humans, RNA, Messenger, Advanced glycation end-products, Cells, Cultured, Mice, Knockout, Aorta, biology, Chemistry, Macrophages, Diabetes, Lactoylglutathione Lyase, Streptozotocin, Atherosclerosis, Plaque, Atherosclerotic, Up-Regulation, Lipoproteins, LDL, Mice, Inbred C57BL, Oxidative Stress, Endocrinology, biology.protein, Cytokines, Endothelium, Vascular, medicine.symptom, Inflammation Mediators, Cardiology and Cardiovascular Medicine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d06d9f40622543323ab73aec14ba02
https://cris.maastrichtuniversity.nl/en/publications/172193de-7599-40a7-88ee-f3237dbc8b89

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Overexpression of Glyoxalase-I Reduces Hyperglycemia-induced Levels of Advanced Glycation End Products and Oxidative Stress in Diabetic Rats

المؤلفون: Olaf Brouwers, Tom Teerlink, Toshio Miyata, Petra Niessen, Peter G. Scheffer, Casper G. Schalkwijk, Michael Brownlee, Coen D.A. Stehouwer, Isabel Ferreira, Patrick Schrauwen

المساهمون: Laboratory Medicine, ICaR - Ischemia and repair, RS: CAPHRI School for Public Health and Primary Care, RS: NUTRIM - R1 - Metabolic Syndrome, Interne Geneeskunde, Epidemiologie, Humane Biologie, MUMC+: KIO Kemta (9), RS: CARIM School for Cardiovascular Diseases

المصدر: Journal of Biological Chemistry, 286(2), 1374-1380. American Society for Biochemistry and Molecular Biology Inc.
Journal of Biological Chemistry, 286(2), 1374-1380. American Society for Biochemistry and Molecular Biology, Inc.
Brouwers, O, Niessen, P M, Ferreira, I, Miyata, T, Scheffer, P G, Teerlink, T, Schrauwen, P, Brownlee, M, Stehouwer, C D A & Schalkwijk, C G 2011, ' Overexpression of Glyoxalase-I Reduces Hyperglycemia-induced Levels of Advanced Glycation End Products and Oxidative Stress in Diabetic Rats ', Journal of Biological Chemistry, vol. 286, no. 2, pp. 1374-1380 . https://doi.org/10.1074/jbc.M110.144097

مصطلحات موضوعية: Glycation End Products, Advanced, medicine.medical_specialty, medicine.disease_cause, Biochemistry, Gene Expression Regulation, Enzymologic, Oxidative Phosphorylation, Diabetes Mellitus, Experimental, Lipid peroxidation, chemistry.chemical_compound, Pregnancy, Glycation, Internal medicine, medicine, Animals, Humans, Rats, Wistar, Molecular Biology, Chemistry, Nitrotyrosine, Methylglyoxal, Lactoylglutathione Lyase, Glyoxal, Cell Biology, Pyruvaldehyde, Malondialdehyde, Streptozotocin, Mitochondria, Rats, Disease Models, Animal, Oxidative Stress, Metabolism, Endocrinology, Hyperglycemia, Advanced glycation end-product, Female, Rats, Transgenic, Biomarkers, Oxidative stress, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9913ae595f6a196b30f4aa1569d367
https://doi.org/10.1074/jbc.M110.144097

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Polymorphisms in glyoxalase 1 gene are not associated with vascular complications: the Hoorn and CoDAM studies

المؤلفون: Giel Nijpels, Carla J.H. van der Kallen, Ellen E. Blaak, L. Engelen, Olaf Brouwers, Ronald M.A. Henry, Robert J. Heine, Marleen M.J. van Greevenbroek, Casper G. Schalkwijk, Hugo ten Cate, Edith J. M. Feskens, Coen D.A. Stehouwer, Isabel Ferreira, Jacqueline M. Dekker

المساهمون: Epidemiology and Data Science, General practice, EMGO - Lifestyle, overweight and diabetes, ICaR - Ischemia and repair

المصدر: Journal of Hypertension 27 (2009) 7
Journal of Hypertension, 27(7), 1399-1403
Engelen, L, Ferreira, I, Brouwers, O, Henry, R M A, Dekker, J M, Nijpels, M G A A M, Heine, R J, van Greevenbroek, M M J, van der Kallen, C J H, Blaak, E E, Feskens, E J M, Ten Cate, H, Stehouwer, C D A & Schalkwijk, C 2009, ' Polymorphisms in glyoxalase 1 gene are not associated with vascular complications: the Hoorn and CoDAM studies ', Journal of Hypertension, vol. 27, no. 7, pp. 1399-1403 . https://doi.org/10.1097/HJH.0b013e32832af6ba
Journal of Hypertension, 27(7), 1399-1403. Lippincott Williams and Wilkins

مصطلحات موضوعية: Glycation End Products, Advanced, medicine.medical_specialty, hypertension, Nutrition and Disease, Physiology, Renal function, Blood Pressure, Single-nucleotide polymorphism, Polymorphism, Single Nucleotide, Cohort Studies, chemistry.chemical_compound, Voeding en Ziekte, Diabetes mellitus, Internal medicine, Internal Medicine, diabetic complications, methylglyoxal, Humans, Medicine, biochemistry, Vascular Diseases, increases, Aged, VLAG, business.industry, Methylglyoxal, Lactoylglutathione Lyase, Type 2 Diabetes Mellitus, Middle Aged, medicine.disease, Pulse pressure, Cross-Sectional Studies, Endocrinology, Blood pressure, chemistry, Arterial stiffness, glycation, cells, Cardiology and Cardiovascular Medicine, business

وصف الملف: application/pdf; application/octet-stream

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b05a9f5bece2d8e9bd882890ee791d
https://hdl.handle.net/1871/27880

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PS1 - 6. Pyridoxamine improves adiposity and insulin resistance in high-fed diet induced obese mice

المؤلفون: Coen D.A. Stehouwer, Olaf Brouwers, Katrien H.J. Gaens, Toshio Miyata, Casper G. Schalkwijk

المصدر: Nederlands Tijdschrift voor Diabetologie. 11:145-146

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Adipokine, Adipose tissue, Type 2 diabetes, medicine.disease, RAGE (receptor), Insulin resistance, Endocrinology, Glycation, hemic and lymphatic diseases, Diabetes mellitus, Internal medicine, Medicine, business, Diet-induced obese

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8e41d171db6f5303ccee5e8f3d5431f9
https://doi.org/10.1007/s12467-013-0084-9

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9

PS3 - 14. Glyoxalase-I overexpression partially prevents diabetes-induced impaired arteriogenesis in a rat hind limb ischemia model

المؤلفون: Coen D.A. Stehouwer, Casper G. Schalkwijk, Mark J. Post, Walter H. Backes, Liang Yu, Jos Slenter, Allard Wagenaar, Olaf Brouwers, Maya S. P. Huijberts, Petra Niessen

المصدر: Nederlands Tijdschrift voor Diabetologie. 9:99-100

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d632366f2f12e3abb8e6d97bb366aeb8
https://doi.org/10.1007/s12467-011-0039-y

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10

Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress

المؤلفون: Michael Brownlee, J. G. R. De Mey, Casper G. Schalkwijk, Olaf Brouwers, Petra Niessen, Toshio Miyata, Guido R.M.M. Haenen, Coen D.A. Stehouwer

المساهمون: Interne Geneeskunde, Moleculaire Genetica, Farmacologie & Toxicologie, RS: NUTRIM - R3 - Chronic inflammatory disease and wasting, RS: NUTRIM - R1 - Metabolic Syndrome, RS: CARIM School for Cardiovascular Diseases

المصدر: Diabetologia, 53(5), 989-1000. Springer, Cham
Diabetologia

مصطلحات موضوعية: GLYOXALASE SYSTEM, Endocrinology, Diabetes and Metabolism, Cell Count, Vasodilation, medicine.disease_cause, chemistry.chemical_compound, Lactoylglutathione lyase, Mesenteric arteries, Cells, Cultured, Glycation, biology, Methylglyoxal, Lactoylglutathione Lyase, INCREASED SERUM-LEVELS, Pyruvaldehyde, Immunohistochemistry, Mesenteric Arteries, Microvascular disease, medicine.anatomical_structure, Rats, Transgenic, GLYCATION END-PRODUCTS, medicine.medical_specialty, Endothelium, Nitric Oxide, Article, Cell Line, Nitric oxide, AGE, Internal medicine, PLASMA-PROTEIN, medicine, Internal Medicine, Animals, Humans, SPONTANEOUSLY HYPERTENSIVE-RATS, TYPE-2 DIABETIC MICE, Analysis of Variance, NITRIC-OXIDE, business.industry, IN-VITRO, Rats, Endocrinology, chemistry, Oxidative stress, Hyperglycemia, CELLS, biology.protein, Rat, Endothelium, Vascular, Reactive Oxygen Species, business, RESISTANCE ARTERY, Glyoxalase system

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c224166b4f1e8c10b0412d3b3e2660

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